{"id":"https://openalex.org/W4384829187","doi":"https://doi.org/10.1158/2767-9764.23713982.v1","title":"FIGURE 1 from Salvage Ipilimumab plus Nivolumab after Anti-PD-1/PD-L1 Therapy in Advanced Hepatocellular Carcinoma","display_name":"FIGURE 1 from Salvage Ipilimumab plus Nivolumab after Anti-PD-1/PD-L1 Therapy in Advanced Hepatocellular Carcinoma","publication_year":2023,"publication_date":"2023-07-20","ids":{"openalex":"https://openalex.org/W4384829187","doi":"https://doi.org/10.1158/2767-9764.23713982.v1"},"language":"en","primary_location":{"id":"doi:10.1158/2767-9764.23713982.v1","doi":"https://doi.org/10.1158/2767-9764.23713982.v1","is_oa":true,"landing_page_url":"https://doi.org/10.1158/2767-9764.23713982.v1","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"volume":null,"type":"other","is_traditional":false,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1158/2767-9764.23713982.v1","any_repository_has_fulltext":null},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5037518890","display_name":"Stephanie Leigh Alden","orcid":"https://orcid.org/0000-0003-0500-8696","observed_orcids":["https://orcid.org/0000-0003-0500-8696"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Stephanie L. Alden","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-0500-8696","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069227296","display_name":"Mir Lim","orcid":"https://orcid.org/0000-0002-6102-0887","observed_orcids":["https://orcid.org/0000-0002-6102-0887"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mir Lim","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-6102-0887","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030296076","display_name":"Chester Kao","orcid":"https://orcid.org/0000-0003-2568-2071","observed_orcids":["https://orcid.org/0000-0003-2568-2071"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Chester Kao","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-2568-2071","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024888979","display_name":"Daniel H. Shu","orcid":"https://orcid.org/0000-0003-1348-5556","observed_orcids":["https://orcid.org/0000-0003-1348-5556"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Daniel Shu","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-1348-5556","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014214683","display_name":"Amit G. Singal","orcid":"https://orcid.org/0000-0002-1172-3971","observed_orcids":["https://orcid.org/0000-0002-1172-3971"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Amit G. Singal","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-1172-3971","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009849305","display_name":"Anne M. Noonan","orcid":"https://orcid.org/0000-0001-8083-8492","observed_orcids":["https://orcid.org/0000-0001-8083-8492"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Anne Noonan","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-8083-8492","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069728610","display_name":"Paige Griffith","orcid":"https://orcid.org/0009-0008-9854-8950","observed_orcids":["https://orcid.org/0009-0008-9854-8950"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Paige Griffith","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0009-0008-9854-8950","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027525899","display_name":"Marina Baretti","orcid":"https://orcid.org/0000-0003-0125-2405","observed_orcids":["https://orcid.org/0000-0003-0125-2405"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Marina Baretti","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-0125-2405","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048843293","display_name":"Won Jin Ho","orcid":"https://orcid.org/0000-0003-2644-5086","observed_orcids":["https://orcid.org/0000-0003-2644-5086"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Won Jin Ho","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-2644-5086","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067085754","display_name":"Ihab R. Kamel","orcid":"https://orcid.org/0000-0003-0511-7796","observed_orcids":["https://orcid.org/0000-0003-0511-7796"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ihab Kamel","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-0511-7796","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076456783","display_name":"Mark M. Yarchoan","orcid":"https://orcid.org/0000-0003-4401-0748","observed_orcids":["https://orcid.org/0000-0003-4401-0748"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mark Yarchoan","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-4401-0748","affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5071411184","display_name":"David Hsiehchen","orcid":"https://orcid.org/0000-0001-9139-302X","observed_orcids":["https://orcid.org/0000-0001-9139-302X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"David Hsiehchen","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-9139-302X","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10158","display_name":"Cancer Immunotherapy and Biomarkers","score":0.6797000169754028,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10158","display_name":"Cancer Immunotherapy and Biomarkers","score":0.6797000169754028,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10073","display_name":"Hepatocellular Carcinoma Treatment and Prognosis","score":0.31790000200271606,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10340","display_name":"Hepatitis B Virus Studies","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ipilimumab","display_name":"ipilimumab","score":0.890999972820282},{"id":"https://openalex.org/keywords/nivolumab","display_name":"nivolumab","score":1.0},{"id":"https://openalex.org/keywords/salvage-therapy","display_name":"salvage therapy","score":0.6740000247955322},{"id":"https://openalex.org/keywords/pd-1-pd-l1-blockade","display_name":"PD-1/PD-L1 blockade","score":0.9399999976158142},{"id":"https://openalex.org/keywords/hepatocellular-carcinoma","display_name":"hepatocellular carcinoma","score":0.8970000147819519},{"id":"https://openalex.org/keywords/advanced-liver-cancer","display_name":"advanced liver cancer","score":0.7179999947547913},{"id":"https://openalex.org/keywords/objective-response","display_name":"objective response","score":0.8119999766349792},{"id":"https://openalex.org/keywords/recist-1-1","display_name":"RECIST 1.1","score":0.9120000004768372},{"id":"https://openalex.org/keywords/best-overall-response","display_name":"best overall response","score":0.6909999847412109}],"concepts":[{"id":"https://openalex.org/C2780030458","wikidata":"https://www.wikidata.org/wiki/Q7041828","display_name":"Nivolumab","level":4,"score":0.91312175989151},{"id":"https://openalex.org/C2781433595","wikidata":"https://www.wikidata.org/wiki/Q2459042","display_name":"Ipilimumab","level":4,"score":0.8353644609451294},{"id":"https://openalex.org/C2778019345","wikidata":"https://www.wikidata.org/wiki/Q1148337","display_name":"Hepatocellular carcinoma","level":2,"score":0.7545692920684814},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7339527010917664},{"id":"https://openalex.org/C2778822529","wikidata":"https://www.wikidata.org/wiki/Q1951525","display_name":"Progressive disease","level":3,"score":0.6219533681869507},{"id":"https://openalex.org/C3019096185","wikidata":"https://www.wikidata.org/wiki/Q1340863","display_name":"Complete response","level":3,"score":0.6178272366523743},{"id":"https://openalex.org/C2779984678","wikidata":"https://www.wikidata.org/wiki/Q2145898","display_name":"Response Evaluation Criteria in Solid Tumors","level":4,"score":0.5639082789421082},{"id":"https://openalex.org/C2781156865","wikidata":"https://www.wikidata.org/wiki/Q827023","display_name":"Lesion","level":2,"score":0.5426817536354065},{"id":"https://openalex.org/C2780775027","wikidata":"https://www.wikidata.org/wiki/Q17141389","display_name":"Salvage therapy","level":3,"score":0.491789847612381},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4364301562309265},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.43090376257896423},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.3017577528953552},{"id":"https://openalex.org/C2777701055","wikidata":"https://www.wikidata.org/wiki/Q1427096","display_name":"Immunotherapy","level":3,"score":0.2884058356285095},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.2047657072544098},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.13708531856536865},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.13320574164390564}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1158/2767-9764.23713982.v1","doi":"https://doi.org/10.1158/2767-9764.23713982.v1","is_oa":true,"landing_page_url":"https://doi.org/10.1158/2767-9764.23713982.v1","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"}],"best_oa_location":{"id":"doi:10.1158/2767-9764.23713982.v1","doi":"https://doi.org/10.1158/2767-9764.23713982.v1","is_oa":true,"landing_page_url":"https://doi.org/10.1158/2767-9764.23713982.v1","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9940000176429749}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4384818497","https://openalex.org/W4384818167","https://openalex.org/W4384829820","https://openalex.org/W4382538971","https://openalex.org/W4382726175","https://openalex.org/W4384829097","https://openalex.org/W4384818490","https://openalex.org/W4379330250","https://openalex.org/W7162650024","https://openalex.org/W4414380338"],"abstract_inverted_index":{"Target":[0],"lesion":[1],"change":[2,7],"and":[3,18],"objective":[4],"response.":[5],"Percent":[6],"in":[8],"patient":[9],"target":[10],"lesion(s),":[11],"determined":[12],"by":[13],"investigator":[14],"review":[15],"of":[16],"pretreatment":[17],"posttreatment":[19],"imaging,":[20],"with":[21],"BOR":[22],"using":[23],"criteria":[24],"from":[25],"RECIST":[26],"v1.1.":[27],"BOR,":[28],"best":[29],"overall":[30],"response;":[31,34,40],"CR,":[32],"complete":[33],"PD,":[35],"progressive":[36],"disease;":[37],"PR,":[38],"partial":[39],"SD,":[41],"stable":[42],"disease.":[43]},"counts_by_year":[],"updated_date":"2026-09-22T06:50:58.402377","created_date":"2023-07-21T00:00:00"}