{"id":"https://openalex.org/W4384699994","doi":"https://doi.org/10.1016/j.clinthera.2023.06.023","title":"Clinical Performance and Safety of Vaginal Ovules in the Local Treatment of Nonspecific Vaginitis: A National, Multicentric Clinical Investigation","display_name":"Clinical Performance and Safety of Vaginal Ovules in the Local Treatment of Nonspecific Vaginitis: A National, Multicentric Clinical Investigation","publication_year":2023,"publication_date":"2023-07-18","ids":{"openalex":"https://openalex.org/W4384699994","doi":"https://doi.org/10.1016/j.clinthera.2023.06.023","pmid":"https://pubmed.ncbi.nlm.nih.gov/37474354"},"language":"en","primary_location":{"id":"doi:10.1016/j.clinthera.2023.06.023","doi":"https://doi.org/10.1016/j.clinthera.2023.06.023","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.clinthera.2023.06.023","pdf_url":"http://www.clinicaltherapeutics.com/article/S0149291823002308/pdf","source":{"id":"https://openalex.org/S185879095","display_name":"Clinical Therapeutics","issn_l":"0149-2918","issn":["0149-2918","1879-114X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Therapeutics","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"http://www.clinicaltherapeutics.com/article/S0149291823002308/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5050392626","display_name":"Daniela Oana Toader","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I162051807","display_name":"Carol Davila University of Medicine and Pharmacy","ror":"https://ror.org/04fm87419","country_code":"RO","type":"education","lineage":["https://openalex.org/I162051807"]},{"id":"https://openalex.org/I4210119198","display_name":"Institutul National pentru Sanatatea Mamei si Copilului \"Alessandrescu-Rusescu\"","ror":"https://ror.org/01tc53f14","country_code":"RO","type":"healthcare","lineage":["https://openalex.org/I4210119198"]}],"countries":["RO"],"is_corresponding":false,"raw_author_name":"Daniela Oana Toader","raw_affiliation_strings":["Department of Obstetrics and Gynecology III, Institutul National pentru Sanatatea Mamei si Copilului Alessandrescu Rusescu, Clinic of Obstetrics and Gynecology Polizu, Bucharest, Romania; Discipline of Obstetrics, Gynecology, and Neonatology, Spitalul Clinic Polizu \"Carol Davila,\" University of Medicine and Pharmacy Bucharest, Bucharest, Romania","Department of Obstetrics and Gynecology III, Institutul National pentru Sanatatea Mamei si Copilului Alessandrescu Rusescu, Clinic of Obstetrics and Gynecology Polizu, Bucharest, Romania","Discipline of Obstetrics, Gynecology, and Neonatology, Spitalul Clinic Polizu \"Carol Davila,\" University of Medicine and Pharmacy Bucharest, Bucharest, Romania"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology III, Institutul National pentru Sanatatea Mamei si Copilului Alessandrescu Rusescu, Clinic of Obstetrics and Gynecology Polizu, Bucharest, Romania; Discipline of Obstetrics, Gynecology, and Neonatology, Spitalul Clinic Polizu \"Carol Davila,\" University of Medicine and Pharmacy Bucharest, Bucharest, Romania","institution_ids":["https://openalex.org/I162051807","https://openalex.org/I4210119198"]},{"raw_affiliation_string":"Department of Obstetrics and Gynecology III, Institutul National pentru Sanatatea Mamei si Copilului Alessandrescu Rusescu, Clinic of Obstetrics and Gynecology Polizu, Bucharest, Romania","institution_ids":["https://openalex.org/I4210119198"]},{"raw_affiliation_string":"Discipline of Obstetrics, Gynecology, and Neonatology, Spitalul Clinic Polizu \"Carol Davila,\" University of Medicine and Pharmacy Bucharest, Bucharest, Romania","institution_ids":["https://openalex.org/I162051807"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021700850","display_name":"Raluca Alexandra Olaru","orcid":"https://orcid.org/0000-0002-0115-9107","observed_orcids":["https://orcid.org/0000-0002-0115-9107"]},"institutions":[{"id":"https://openalex.org/I162051807","display_name":"Carol Davila University of Medicine and Pharmacy","ror":"https://ror.org/04fm87419","country_code":"RO","type":"education","lineage":["https://openalex.org/I162051807"]},{"id":"https://openalex.org/I4210119198","display_name":"Institutul National pentru Sanatatea Mamei si Copilului \"Alessandrescu-Rusescu\"","ror":"https://ror.org/01tc53f14","country_code":"RO","type":"healthcare","lineage":["https://openalex.org/I4210119198"]}],"countries":["RO"],"is_corresponding":false,"raw_author_name":"Raluca Alexandra Olaru","raw_affiliation_strings":["Department of Obstetrics and Gynecology III, Institutul National pentru Sanatatea Mamei si Copilului Alessandrescu Rusescu, Clinic of Obstetrics and Gynecology Polizu, Bucharest, Romania; Discipline of Obstetrics, Gynecology, and Neonatology, Spitalul Clinic Polizu \"Carol Davila,\" University of Medicine and Pharmacy Bucharest, Bucharest, Romania","Department of Obstetrics and Gynecology III, Institutul National pentru Sanatatea Mamei si Copilului Alessandrescu Rusescu, Clinic of Obstetrics and Gynecology Polizu, Bucharest, Romania","Discipline of Obstetrics, Gynecology, and Neonatology, Spitalul Clinic Polizu \"Carol Davila,\" University of Medicine and Pharmacy Bucharest, Bucharest, Romania"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology III, Institutul National pentru Sanatatea Mamei si Copilului Alessandrescu Rusescu, Clinic of Obstetrics and Gynecology Polizu, Bucharest, Romania; Discipline of Obstetrics, Gynecology, and Neonatology, Spitalul Clinic Polizu \"Carol Davila,\" University of Medicine and Pharmacy Bucharest, Bucharest, Romania","institution_ids":["https://openalex.org/I162051807","https://openalex.org/I4210119198"]},{"raw_affiliation_string":"Department of Obstetrics and Gynecology III, Institutul National pentru Sanatatea Mamei si Copilului Alessandrescu Rusescu, Clinic of Obstetrics and Gynecology Polizu, Bucharest, Romania","institution_ids":["https://openalex.org/I4210119198"]},{"raw_affiliation_string":"Discipline of Obstetrics, Gynecology, and Neonatology, Spitalul Clinic Polizu \"Carol Davila,\" University of Medicine and Pharmacy Bucharest, Bucharest, Romania","institution_ids":["https://openalex.org/I162051807"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053224290","display_name":"Dominic Gabriel Iliescu","orcid":"https://orcid.org/0000-0002-7823-3387","observed_orcids":["https://orcid.org/0000-0002-7823-3387"]},"institutions":[{"id":"https://openalex.org/I28109999","display_name":"University of Medicine and Pharmacy of Craiova","ror":"https://ror.org/031d5vw30","country_code":"RO","type":"education","lineage":["https://openalex.org/I28109999"]}],"countries":["RO"],"is_corresponding":false,"raw_author_name":"Dominic-Gabriel Iliescu","raw_affiliation_strings":["Discipline of Obstetrics and Gynecology VIII, University of Medicine and Pharmacy Craiova, Craiova, Romania"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Discipline of Obstetrics and Gynecology VIII, University of Medicine and Pharmacy Craiova, Craiova, Romania","institution_ids":["https://openalex.org/I28109999"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041826913","display_name":"Ramona Petrita","orcid":"https://orcid.org/0000-0002-8626-1222","observed_orcids":["https://orcid.org/0000-0002-8626-1222"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Ramona Petrita","raw_affiliation_strings":["Biometrics Unit, MDX Research, Timisoara, Romania. Electronic address: ramona.petrita@mdxresearch.eu","Biometrics Unit, MDX Research, Timisoara, Romania"],"raw_orcid":"https://orcid.org/0000-0002-8626-1222","affiliations":[{"raw_affiliation_string":"Biometrics Unit, MDX Research, Timisoara, Romania. Electronic address: ramona.petrita@mdxresearch.eu","institution_ids":[]},{"raw_affiliation_string":"Biometrics Unit, MDX Research, Timisoara, Romania","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091949841","display_name":"Florentina Liliana Calancea","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Florentina Liliana Calancea","raw_affiliation_strings":["Biometrics Unit, MDX Research, Timisoara, Romania"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biometrics Unit, MDX Research, Timisoara, Romania","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5006938036","display_name":"Izabella Petre","orcid":"https://orcid.org/0000-0001-5835-5339","observed_orcids":["https://orcid.org/0000-0001-5835-5339"]},"institutions":[{"id":"https://openalex.org/I4210088791","display_name":"Victor Babe\u0219 University of Medicine and Pharmacy Timi\u0219oara","ror":"https://ror.org/00afdp487","country_code":"RO","type":"education","lineage":["https://openalex.org/I4210088791"]}],"countries":["RO"],"is_corresponding":false,"raw_author_name":"Izabella Petre","raw_affiliation_strings":["Discipline of Obstetrics and Gynecology XII, \"Victor Babes\" University of Medicine and Pharmacy, Timisoara, Romania"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Discipline of Obstetrics and Gynecology XII, \"Victor Babes\" University of Medicine and Pharmacy, Timisoara, Romania","institution_ids":["https://openalex.org/I4210088791"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5041826913"],"corresponding_institution_ids":[],"apc_list":{"value":4210,"currency":"USD","value_usd":4210},"apc_paid":{"value":4210,"currency":"USD","value_usd":4210},"fwci":0.6336,"has_fulltext":true,"cited_by_count":4,"citation_normalized_percentile":{"value":0.58104708,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"45","issue":"9","first_page":"873","last_page":"880"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10428","display_name":"Reproductive tract infections research","score":0.9932000041007996,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10428","display_name":"Reproductive tract infections research","score":0.9932000041007996,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11589","display_name":"Gynecological conditions and treatments","score":0.002899999963119626,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10694","display_name":"Menopause: Health Impacts and Treatments","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nonspecific-vaginitis","display_name":"nonspecific vaginitis","score":0.9950000047683716},{"id":"https://openalex.org/keywords/abnormal-vaginal-discharge","display_name":"abnormal vaginal discharge","score":0.8930000066757202},{"id":"https://openalex.org/keywords/vaginal-ph","display_name":"vaginal pH","score":0.9480000138282776},{"id":"https://openalex.org/keywords/vaginal-microbiota","display_name":"vaginal microbiota","score":0.8899999856948853},{"id":"https://openalex.org/keywords/vaginal-inflammation","display_name":"vaginal inflammation","score":0.9800000190734863},{"id":"https://openalex.org/keywords/vulvovaginitis","display_name":"vulvovaginitis","score":0.906000018119812}],"concepts":[{"id":"https://openalex.org/C2779952448","wikidata":"https://www.wikidata.org/wiki/Q804521","display_name":"Bacterial vaginosis","level":2,"score":0.9479905366897583},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9437898397445679},{"id":"https://openalex.org/C2777617518","wikidata":"https://www.wikidata.org/wiki/Q676191","display_name":"Vaginitis","level":2,"score":0.7981681823730469},{"id":"https://openalex.org/C2777700855","wikidata":"https://www.wikidata.org/wiki/Q18211693","display_name":"Vaginal disease","level":3,"score":0.6049138903617859},{"id":"https://openalex.org/C2776393945","wikidata":"https://www.wikidata.org/wiki/Q778502","display_name":"Vaginal discharge","level":2,"score":0.5543726682662964},{"id":"https://openalex.org/C2777744392","wikidata":"https://www.wikidata.org/wiki/Q5880","display_name":"Vagina","level":2,"score":0.47458624839782715},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.4682416021823883},{"id":"https://openalex.org/C2777023796","wikidata":"https://www.wikidata.org/wiki/Q745865","display_name":"Trichomoniasis","level":2,"score":0.45666295289993286},{"id":"https://openalex.org/C2910222780","wikidata":"https://www.wikidata.org/wiki/Q745865","display_name":"Trichomonas Vaginitis","level":3,"score":0.43427643179893494},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.4020211100578308},{"id":"https://openalex.org/C131872663","wikidata":"https://www.wikidata.org/wiki/Q5284418","display_name":"Obstetrics","level":1,"score":0.33419230580329895},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.22200754284858704},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007249","descriptor_name":"Inflammation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014247","descriptor_name":"Trichomonas Vaginitis","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D014247","descriptor_name":"Trichomonas Vaginitis","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D014627","descriptor_name":"Vaginitis","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D014627","descriptor_name":"Vaginitis","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D014627","descriptor_name":"Vaginitis","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":true},{"descriptor_ui":"D016585","descriptor_name":"Vaginosis, Bacterial","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D016585","descriptor_name":"Vaginosis, Bacterial","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D016585","descriptor_name":"Vaginosis, Bacterial","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D019522","descriptor_name":"Vaginal Discharge","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":true},{"descriptor_ui":"D056771","descriptor_name":"Ovule","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1016/j.clinthera.2023.06.023","doi":"https://doi.org/10.1016/j.clinthera.2023.06.023","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.clinthera.2023.06.023","pdf_url":"http://www.clinicaltherapeutics.com/article/S0149291823002308/pdf","source":{"id":"https://openalex.org/S185879095","display_name":"Clinical Therapeutics","issn_l":"0149-2918","issn":["0149-2918","1879-114X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Therapeutics","raw_type":"journal-article"},{"id":"doi:10.1101/2023.05.09.23289715","doi":"https://doi.org/10.1101/2023.05.09.23289715","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1101/2023.05.09.23289715","pdf_url":"https://www.medrxiv.org/content/medrxiv/early/2023/05/16/2023.05.09.23289715.full.pdf","source":{"id":"https://openalex.org/S3005729997","display_name":"medRxiv","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":["https://openalex.org/P4310315909"],"host_organization_lineage_names":["Cold Spring Harbor Laboratory Press"],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"medRxiv","raw_type":"posted-content"},{"id":"pmid:37474354","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37474354","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical therapeutics","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1016/j.clinthera.2023.06.023","doi":"https://doi.org/10.1016/j.clinthera.2023.06.023","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.clinthera.2023.06.023","pdf_url":"http://www.clinicaltherapeutics.com/article/S0149291823002308/pdf","source":{"id":"https://openalex.org/S185879095","display_name":"Clinical Therapeutics","issn_l":"0149-2918","issn":["0149-2918","1879-114X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Therapeutics","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9907000064849854,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Clinical Trial","id":"https://openalex.org/study-designs/clinical-trial"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4384699994.pdf","grobid_xml":"https://content.openalex.org/works/W4384699994.grobid-xml"},"referenced_works_count":33,"referenced_works":["https://openalex.org/W852680401","https://openalex.org/W1182335463","https://openalex.org/W1511839743","https://openalex.org/W1963810427","https://openalex.org/W1980591639","https://openalex.org/W2011569383","https://openalex.org/W2019006753","https://openalex.org/W2020049581","https://openalex.org/W2056793135","https://openalex.org/W2071746413","https://openalex.org/W2096314241","https://openalex.org/W2105178581","https://openalex.org/W2115597247","https://openalex.org/W2119670078","https://openalex.org/W2143163821","https://openalex.org/W2151169921","https://openalex.org/W2241030575","https://openalex.org/W2335809812","https://openalex.org/W2341945751","https://openalex.org/W2397511034","https://openalex.org/W2599064062","https://openalex.org/W2613491369","https://openalex.org/W2783722756","https://openalex.org/W2788489027","https://openalex.org/W2793653046","https://openalex.org/W2971673731","https://openalex.org/W3039739672","https://openalex.org/W3081155815","https://openalex.org/W3141383887","https://openalex.org/W3173466859","https://openalex.org/W3210042635","https://openalex.org/W4366392584","https://openalex.org/W6623699261"],"related_works":["https://openalex.org/W4376618521","https://openalex.org/W4391293010","https://openalex.org/W2599064062","https://openalex.org/W2026509949","https://openalex.org/W1578872099","https://openalex.org/W2089635226","https://openalex.org/W2901857470","https://openalex.org/W7111827348","https://openalex.org/W195429316","https://openalex.org/W52304730"],"abstract_inverted_index":{"PURPOSE:":[0],"Nonspecific":[1],"vaginitis":[2],"is":[3,15,199],"a":[4,142,187],"distinct":[5,98],"clinical":[6,68,197,204],"entity":[7],"with":[8,23,45,52,95,192],"particular":[9],"microscopic":[10,70],"and":[11,56,59,69,85,165,214],"immunologic":[12],"features.":[13],"There":[14],"currently":[16],"no":[17],"standard":[18],"of":[19,28,43,118,152,158,169,206,212],"care":[20,211],"for":[21,150],"women":[22,191],"nonspecific":[24,193],"vaginitis.":[25,194],"The":[26,89,105,114,129,137],"aim":[27],"our":[29],"study":[30,65,90,106,131,154,172],"was":[31,133],"to":[32,201,220],"assess":[33],"the":[34,64,146,153,159,203,207],"change":[35,77,81],"in":[36,50,78,82,190,209],"vaginal":[37,54,74,79,83,86,147,162,215],"symptoms":[38,148],"score":[39,149],"after":[40],"3":[41,134],"months":[42],"treatment":[44,115,189],"an":[46],"intravaginal":[47,138,176],"medical":[48,139,177],"device":[49,140,178,208],"participants":[51,94],"abnormal":[53],"discharge":[55,75],"specific":[57],"signs":[58,168],"symptoms.":[60],"As":[61],"secondary":[62,219],"objectives,":[63],"analyzed":[66],"other":[67],"features,":[71],"such":[72],"as":[73,186],"aspect,":[76],"pH,":[80],"microbiome,":[84],"inflammation.":[87],"METHODS:":[88],"population":[91],"included":[92,108],"47":[93],"symptomatic":[96],"vulvovaginitis,":[97],"from":[99,112],"candidiasis,":[100],"trichomoniasis,":[101],"or":[102,218],"bacterial":[103],"vaginosis.":[104],"design":[107],"2":[109],"research":[110],"sites":[111],"Romania.":[113],"protocol":[116],"consisted":[117],"1":[119],"ovule":[120],"per":[121],"day":[122],"inserted":[123],"intravaginally":[124],"during":[125],"15":[126],"consecutive":[127],"days.":[128],"total":[130],"duration":[132],"months.":[135],"FINDINGS:":[136],"had":[141,179],"positive":[143],"impact":[144],"on":[145],"72.34%":[151],"participants.":[155],"Topical":[156],"administration":[157],"ovules":[160],"balanced":[161],"pH":[163],"values":[164],"significantly":[166],"reduced":[167],"inflammation":[170],"between":[171],"visits.":[173],"IMPLICATIONS:":[174],"This":[175],"curative":[180],"effects":[181],"that":[182],"support":[183],"its":[184],"use":[185],"stand-alone":[188],"A":[195],"second":[196],"investigation":[198],"ongoing":[200],"evaluate":[202],"efficacy":[205],"postoperative":[210],"cervical":[213],"wounds":[216],"traumatic":[217],"surgical":[221],"interventions.":[222],"CLINICALTRIALS:":[223],"gov":[224],"identifier:":[225],"NCT04735705.":[226]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2}],"updated_date":"2026-11-09T13:22:03.289127","created_date":"2023-07-20T00:00:00"}