{"id":"https://openalex.org/W4384025716","doi":"https://doi.org/10.1016/j.jaac.2023.05.034","title":"Effects of Pre- and Postnatal Early-Life Stress on Internalizing, Adiposity, and Their Comorbidity","display_name":"Effects of Pre- and Postnatal Early-Life Stress on Internalizing, Adiposity, and Their Comorbidity","publication_year":2023,"publication_date":"2023-07-12","ids":{"openalex":"https://openalex.org/W4384025716","doi":"https://doi.org/10.1016/j.jaac.2023.05.034","pmid":"https://pubmed.ncbi.nlm.nih.gov/37453606"},"language":"en","primary_location":{"id":"doi:10.1016/j.jaac.2023.05.034","doi":"https://doi.org/10.1016/j.jaac.2023.05.034","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jaac.2023.05.034","pdf_url":"http://www.jaacap.org/article/S0890856723003830/pdf","source":{"id":"https://openalex.org/S60711021","display_name":"Journal of the American Academy of Child & Adolescent Psychiatry","issn_l":"0890-8567","issn":["0890-8567","1527-5418"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American Academy of Child & Adolescent Psychiatry","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"http://www.jaacap.org/article/S0890856723003830/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5083208603","display_name":"Serena Defina","orcid":"https://orcid.org/0000-0003-3344-6597","observed_orcids":["https://orcid.org/0000-0003-3344-6597"]},"institutions":[{"id":"https://openalex.org/I2801952686","display_name":"Erasmus MC","ror":"https://ror.org/018906e22","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I2801952686"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Serena Defina","raw_affiliation_strings":["Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands"],"raw_orcid":"https://orcid.org/0000-0003-3344-6597","affiliations":[{"raw_affiliation_string":"Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands","institution_ids":["https://openalex.org/I2801952686"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025051531","display_name":"Tom Woofenden","orcid":"https://orcid.org/0009-0001-2203-7985","observed_orcids":["https://orcid.org/0009-0001-2203-7985"]},"institutions":[{"id":"https://openalex.org/I51601045","display_name":"University of Bath","ror":"https://ror.org/002h8g185","country_code":"GB","type":"education","lineage":["https://openalex.org/I51601045"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Tom Woofenden","raw_affiliation_strings":["University of Bath, Bath, United Kingdom"],"raw_orcid":"https://orcid.org/0009-0001-2203-7985","affiliations":[{"raw_affiliation_string":"University of Bath, Bath, United Kingdom","institution_ids":["https://openalex.org/I51601045"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018218384","display_name":"Vilte Baltramonaityte","orcid":"https://orcid.org/0000-0002-9776-735X","observed_orcids":["https://orcid.org/0000-0002-9776-735X"]},"institutions":[{"id":"https://openalex.org/I51601045","display_name":"University of Bath","ror":"https://ror.org/002h8g185","country_code":"GB","type":"education","lineage":["https://openalex.org/I51601045"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Vilte Baltramonaityte","raw_affiliation_strings":["University of Bath, Bath, United Kingdom"],"raw_orcid":"https://orcid.org/0000-0002-9776-735X","affiliations":[{"raw_affiliation_string":"University of Bath, Bath, United Kingdom","institution_ids":["https://openalex.org/I51601045"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085756728","display_name":"Carmine Maria Pariante","orcid":"https://orcid.org/0000-0002-9132-5091","observed_orcids":["https://orcid.org/0000-0002-9132-5091"]},"institutions":[{"id":"https://openalex.org/I183935753","display_name":"King's College London","ror":"https://ror.org/0220mzb33","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I183935753"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Carmine M. Pariante","raw_affiliation_strings":["King's College London, London, United Kingdom"],"raw_orcid":"https://orcid.org/0000-0002-9132-5091","affiliations":[{"raw_affiliation_string":"King's College London, London, United Kingdom","institution_ids":["https://openalex.org/I183935753"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078391768","display_name":"Karim Lekadir","orcid":"https://orcid.org/0000-0002-9456-1612","observed_orcids":["https://orcid.org/0000-0002-9456-1612"]},"institutions":[{"id":"https://openalex.org/I71999127","display_name":"Universitat de Barcelona","ror":"https://ror.org/021018s57","country_code":"ES","type":"education","lineage":["https://openalex.org/I71999127"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Karim Lekadir","raw_affiliation_strings":["University of Barcelona, Barcelona, Spain"],"raw_orcid":"https://orcid.org/0000-0002-9456-1612","affiliations":[{"raw_affiliation_string":"University of Barcelona, Barcelona, Spain","institution_ids":["https://openalex.org/I71999127"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012921360","display_name":"Vincent W. V. Jaddoe","orcid":"https://orcid.org/0000-0003-2939-0041","observed_orcids":["https://orcid.org/0000-0003-2939-0041"]},"institutions":[{"id":"https://openalex.org/I2801952686","display_name":"Erasmus MC","ror":"https://ror.org/018906e22","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I2801952686"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Vincent W.V. Jaddoe","raw_affiliation_strings":["Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands"],"raw_orcid":"https://orcid.org/0000-0003-2939-0041","affiliations":[{"raw_affiliation_string":"Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands","institution_ids":["https://openalex.org/I2801952686"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008568575","display_name":"Fadila Serdarevi\u0107","orcid":"https://orcid.org/0000-0002-5803-7979","observed_orcids":["https://orcid.org/0000-0002-5803-7979"]},"institutions":[{"id":"https://openalex.org/I2801952686","display_name":"Erasmus MC","ror":"https://ror.org/018906e22","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I2801952686"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Fadila Serdarevic","raw_affiliation_strings":["Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands"],"raw_orcid":"https://orcid.org/0000-0002-5803-7979","affiliations":[{"raw_affiliation_string":"Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands","institution_ids":["https://openalex.org/I2801952686"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076290987","display_name":"Henning W. Tiemeier","orcid":"https://orcid.org/0000-0002-4395-1397","observed_orcids":["https://orcid.org/0000-0002-4395-1397"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I2801952686","display_name":"Erasmus MC","ror":"https://ror.org/018906e22","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I2801952686"]}],"countries":["NL","US"],"is_corresponding":false,"raw_author_name":"Henning Tiemeier","raw_affiliation_strings":["Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands; Harvard T.H. Chan School of Public Health, Harvard University, Boston, Massachusetts","Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands","Harvard T.H. Chan School of Public Health, Harvard University, Boston, Massachusetts"],"raw_orcid":"https://orcid.org/0000-0002-4395-1397","affiliations":[{"raw_affiliation_string":"Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands; Harvard T.H. Chan School of Public Health, Harvard University, Boston, Massachusetts","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I2801952686"]},{"raw_affiliation_string":"Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands","institution_ids":["https://openalex.org/I2801952686"]},{"raw_affiliation_string":"Harvard T.H. Chan School of Public Health, Harvard University, Boston, Massachusetts","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021523749","display_name":"Esther Walton","orcid":"https://orcid.org/0000-0002-0935-2200","observed_orcids":["https://orcid.org/0000-0002-0935-2200"]},"institutions":[{"id":"https://openalex.org/I51601045","display_name":"University of Bath","ror":"https://ror.org/002h8g185","country_code":"GB","type":"education","lineage":["https://openalex.org/I51601045"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Esther Walton","raw_affiliation_strings":["University of Bath, Bath, United Kingdom"],"raw_orcid":"https://orcid.org/0000-0002-0935-2200","affiliations":[{"raw_affiliation_string":"University of Bath, Bath, United Kingdom","institution_ids":["https://openalex.org/I51601045"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044611532","display_name":"Janine F. Felix","orcid":"https://orcid.org/0000-0002-9801-5774","observed_orcids":["https://orcid.org/0000-0002-9801-5774"]},"institutions":[{"id":"https://openalex.org/I2801952686","display_name":"Erasmus MC","ror":"https://ror.org/018906e22","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I2801952686"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Janine F. Felix","raw_affiliation_strings":["Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands","institution_ids":["https://openalex.org/I2801952686"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5047142862","display_name":"Charlotte A. M. Cecil","orcid":"https://orcid.org/0000-0002-2389-5922","observed_orcids":["https://orcid.org/0000-0002-2389-5922"]},"institutions":[{"id":"https://openalex.org/I2800006345","display_name":"Leiden University Medical Center","ror":"https://ror.org/05xvt9f17","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2800006345"]},{"id":"https://openalex.org/I2801952686","display_name":"Erasmus MC","ror":"https://ror.org/018906e22","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I2801952686"]}],"countries":["NL"],"is_corresponding":true,"raw_author_name":"Charlotte A.M. Cecil","raw_affiliation_strings":["Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands; Leiden University Medical Center, Leiden, the Netherlands. Electronic address: c.cecil@erasmusmc.nl","Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands","Leiden University Medical Center, Leiden, the Netherlands"],"raw_orcid":"https://orcid.org/0000-0002-2389-5922","affiliations":[{"raw_affiliation_string":"Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands; Leiden University Medical Center, Leiden, the Netherlands. Electronic address: c.cecil@erasmusmc.nl","institution_ids":["https://openalex.org/I2800006345","https://openalex.org/I2801952686"]},{"raw_affiliation_string":"Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands","institution_ids":["https://openalex.org/I2801952686"]},{"raw_affiliation_string":"Leiden University Medical Center, Leiden, the Netherlands","institution_ids":["https://openalex.org/I2800006345"]}]}],"institutions":[],"countries_distinct_count":4,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5047142862"],"corresponding_institution_ids":["https://openalex.org/I2800006345","https://openalex.org/I2801952686"],"apc_list":{"value":3000,"currency":"USD","value_usd":3000},"apc_paid":{"value":3000,"currency":"USD","value_usd":3000},"fwci":3.9316,"has_fulltext":true,"cited_by_count":16,"citation_normalized_percentile":{"value":0.94006122,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":95,"max":99},"biblio":{"volume":"63","issue":"2","first_page":"255","last_page":"265"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10786","display_name":"Maternal Mental Health During Pregnancy and Postpartum","score":0.5067999958992004,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10786","display_name":"Maternal Mental Health During Pregnancy and Postpartum","score":0.5067999958992004,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10426","display_name":"Child Abuse and Trauma","score":0.25,"subfield":{"id":"https://openalex.org/subfields/3203","display_name":"Clinical Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10182","display_name":"Child and Adolescent Psychosocial and Emotional Development","score":0.09470000118017197,"subfield":{"id":"https://openalex.org/subfields/3203","display_name":"Clinical Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/early-life-stress","display_name":"early life stress","score":0.9800000190734863},{"id":"https://openalex.org/keywords/prenatal-stress","display_name":"prenatal stress","score":0.9879999756813049},{"id":"https://openalex.org/keywords/postpartum-stress","display_name":"postpartum stress","score":0.9990000128746033},{"id":"https://openalex.org/keywords/internalizing-problems","display_name":"internalizing problems","score":0.9449999928474426},{"id":"https://openalex.org/keywords/depression","display_name":"depression","score":0.6159999966621399},{"id":"https://openalex.org/keywords/childhood-obesity","display_name":"childhood obesity","score":0.7329999804496765},{"id":"https://openalex.org/keywords/adiposity","display_name":"adiposity","score":0.9559999704360962},{"id":"https://openalex.org/keywords/adolescent-mental-health","display_name":"adolescent mental health","score":0.5680000185966492},{"id":"https://openalex.org/keywords/cardiometabolic-health","display_name":"cardiometabolic health","score":0.7910000085830688},{"id":"https://openalex.org/keywords/avon-longitudinal-study-of-parents-and-children","display_name":"Avon Longitudinal Study of Parents and Children","score":0.6669999957084656},{"id":"https://openalex.org/keywords/sex-differences","display_name":"sex differences","score":0.6359999775886536},{"id":"https://openalex.org/keywords/ethnic-differences","display_name":"ethnic differences","score":0.3840000033378601},{"id":"https://openalex.org/keywords/socioeconomic-status","display_name":"socioeconomic status","score":0.4779999852180481},{"id":"https://openalex.org/keywords/maternal-education","display_name":"maternal education","score":0.3580000102519989},{"id":"https://openalex.org/keywords/maternal-depression","display_name":"maternal depression","score":0.41200000047683716},{"id":"https://openalex.org/keywords/smoking-during-pregnancy","display_name":"smoking during pregnancy","score":0.46700000762939453}],"concepts":[{"id":"https://openalex.org/C2779159551","wikidata":"https://www.wikidata.org/wiki/Q1414874","display_name":"Comorbidity","level":2,"score":0.8180865049362183},{"id":"https://openalex.org/C2776443723","wikidata":"https://www.wikidata.org/wiki/Q7240529","display_name":"Prenatal stress","level":4,"score":0.7493069171905518},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6356289386749268},{"id":"https://openalex.org/C2776867660","wikidata":"https://www.wikidata.org/wiki/Q1814941","display_name":"Depression (economics)","level":2,"score":0.5824986696243286},{"id":"https://openalex.org/C156957248","wikidata":"https://www.wikidata.org/wiki/Q1862216","display_name":"Odds ratio","level":2,"score":0.5342644453048706},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.5130085349082947},{"id":"https://openalex.org/C511355011","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Obesity","level":2,"score":0.5003941059112549},{"id":"https://openalex.org/C201614185","wikidata":"https://www.wikidata.org/wiki/Q396833","display_name":"In utero","level":4,"score":0.4530071020126343},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.44904860854148865},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.4222466051578522},{"id":"https://openalex.org/C172680121","wikidata":"https://www.wikidata.org/wiki/Q26513","display_name":"Fetus","level":3,"score":0.27288901805877686},{"id":"https://openalex.org/C46973012","wikidata":"https://www.wikidata.org/wiki/Q28627","display_name":"Gestation","level":3,"score":0.24968191981315613},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.07750290632247925},{"id":"https://openalex.org/C139719470","wikidata":"https://www.wikidata.org/wiki/Q39680","display_name":"Macroeconomics","level":1,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000076783","descriptor_name":"Adverse Childhood Experiences","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015897","descriptor_name":"Comorbidity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D050154","descriptor_name":"Adiposity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1016/j.jaac.2023.05.034","doi":"https://doi.org/10.1016/j.jaac.2023.05.034","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jaac.2023.05.034","pdf_url":"http://www.jaacap.org/article/S0890856723003830/pdf","source":{"id":"https://openalex.org/S60711021","display_name":"Journal of the American Academy of Child & Adolescent Psychiatry","issn_l":"0890-8567","issn":["0890-8567","1527-5418"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American Academy of Child & Adolescent Psychiatry","raw_type":"journal-article"},{"id":"pmid:37453606","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37453606","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American Academy of Child and Adolescent Psychiatry","raw_type":"Journal Article"},{"id":"pmh:oai:pure.eur.nl:openaire/ae3eaa7f-2596-4924-9c0b-2ef5cc27069a","doi":null,"is_oa":true,"landing_page_url":"https://pure.eur.nl/en/publications/ae3eaa7f-2596-4924-9c0b-2ef5cc27069a","pdf_url":null,"source":{"id":"https://openalex.org/S4306401266","display_name":"EUR Research Repository (Erasmus University Rotterdam)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I913958620","host_organization_name":"Erasmus University Rotterdam","host_organization_lineage":["https://openalex.org/I913958620"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"the EarlyCause Consortium, Defina, S, Woofenden, T, Baltramonaityte, V, Pariante, C M, Lekadir, K, Jaddoe, V W V, Serdarevic, F, Tiemeier, H, Walton, E, Felix, J F & Cecil, C A M 2024, 'Effects of Pre- and Postnatal Early-Life Stress on Internalizing, Adiposity, and Their Comorbidity', Journal of the American Academy of Child and Adolescent Psychiatry, vol. 63, no. 2, pp. 255-265. https://doi.org/10.1016/j.jaac.2023.05.034","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1016/j.jaac.2023.05.034","doi":"https://doi.org/10.1016/j.jaac.2023.05.034","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jaac.2023.05.034","pdf_url":"http://www.jaacap.org/article/S0890856723003830/pdf","source":{"id":"https://openalex.org/S60711021","display_name":"Journal of the American Academy of Child & Adolescent Psychiatry","issn_l":"0890-8567","issn":["0890-8567","1527-5418"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American Academy of Child & Adolescent Psychiatry","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G1067152967","display_name":null,"funder_award_id":"EP/Y015037/1","funder_id":"https://openalex.org/F4320314731","funder_display_name":"UK Research and Innovation"},{"id":"https://openalex.org/G133902920","display_name":null,"funder_award_id":"MR/J002739/1","funder_id":"https://openalex.org/F4320307758","funder_display_name":"Eli Lilly and Company"},{"id":"https://openalex.org/G1990791044","display_name":null,"funder_award_id":"MR/L014815/1","funder_id":"https://openalex.org/F4320311198","funder_display_name":"South London and Maudsley NHS Foundation Trust"},{"id":"https://openalex.org/G2014347438","display_name":"AMBROSIAC - A Menu for Brain Responses Opposing Stress-Induced Alterations in Cognition","funder_award_id":"MR/N029488/1","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G2094987202","display_name":"MICA: Immuno-psychiatry: a consortium to test the opportunity for immunotherapeutics in psychiatry","funder_award_id":"MR/L014815/1","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G2360703732","display_name":null,"funder_award_id":"MR/J002739/1","funder_id":"https://openalex.org/F4320319990","funder_display_name":"National Institute for Health and Care Research"},{"id":"https://openalex.org/G2632041694","display_name":null,"funder_award_id":"016.VICI.170.200","funder_id":"https://openalex.org/F4320321007","funder_display_name":"ZonMw"},{"id":"https://openalex.org/G297527364","display_name":"EU Patient- cEntric clinicAl tRial pLatform","funder_award_id":"853966","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G3181733518","display_name":"The Avon Longitudinal Study of Parents and Children (ALSPAC): A multi-generation, longitudinal resource","funder_award_id":"MC_PC_19009","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G3348134642","display_name":null,"funder_award_id":"MR/L014815/1","funder_id":"https://openalex.org/F4320319990","funder_display_name":"National Institute for Health and Care Research"},{"id":"https://openalex.org/G3535608949","display_name":"Consortium of Neuroimmunology of Mood Disorders and Alzheimer's Disease.","funder_award_id":"104025","funder_id":"https://openalex.org/F4320311904","funder_display_name":"Wellcome Trust"},{"id":"https://openalex.org/G3639234831","display_name":null,"funder_award_id":"733206","funder_id":"https://openalex.org/F4320338335","funder_display_name":"H2020 European Research Council"},{"id":"https://openalex.org/G3653777572","display_name":"The Avon Longitudinal Study of Parents and Children (ALSPAC): A multi- generation, longitudinal resource focusing on life course health and well- being.","funder_award_id":"217065/Z/19/Z","funder_id":"https://openalex.org/F4320311904","funder_display_name":"Wellcome Trust"},{"id":"https://openalex.org/G3909006727","display_name":null,"funder_award_id":"874739","funder_id":"https://openalex.org/F4320332999","funder_display_name":"Horizon 2020 Framework Programme"},{"id":"https://openalex.org/G4250557856","display_name":null,"funder_award_id":"848158","funder_id":"https://openalex.org/F4320338335","funder_display_name":"H2020 European Research Council"},{"id":"https://openalex.org/G4342926802","display_name":null,"funder_award_id":"MR/J002739/1","funder_id":"https://openalex.org/F4320311198","funder_display_name":"South London and Maudsley NHS Foundation Trust"},{"id":"https://openalex.org/G4805497331","display_name":"The Avon Longitudinal Study of Parents and Children: An international resource for population\ngenomics and lifecourse epidemiology. Core Programme Support 2011-2015 and Core programme support 2014-2019","funder_award_id":"MC_PC_15018","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G4818068823","display_name":"NIHR Senior Investigator Award","funder_award_id":"NIHR201376","funder_id":"https://openalex.org/F4320319990","funder_display_name":"National Institute for Health and Care Research"},{"id":"https://openalex.org/G5231023664","display_name":null,"funder_award_id":"VICI.170.200","funder_id":"https://openalex.org/F4320321007","funder_display_name":"ZonMw"},{"id":"https://openalex.org/G5276953297","display_name":"NIHR Senior Investigator Award","funder_award_id":"NF-SI-0616-10074","funder_id":"https://openalex.org/F4320319990","funder_display_name":"National Institute for Health and Care Research"},{"id":"https://openalex.org/G5562631338","display_name":null,"funder_award_id":"102215/2/13/2","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G5632776011","display_name":null,"funder_award_id":"EP/Y015037/1","funder_id":"https://openalex.org/F4320334678","funder_display_name":"European Research Council"},{"id":"https://openalex.org/G5855629232","display_name":"Persistent Fatigue Induced by Interferon-alpha: A New Immunological Model for Chronic Fatigue Syndrome","funder_award_id":"MR/J002739/1","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G6082777387","display_name":"Scaling-up Health-Arts Programmes: Implementation and Effectiveness Research (SHAPER)","funder_award_id":"219425/Z/19/Z","funder_id":"https://openalex.org/F4320311904","funder_display_name":"Wellcome Trust"},{"id":"https://openalex.org/G792825315","display_name":null,"funder_award_id":"217065/Z/19/","funder_id":"https://openalex.org/F4320311904","funder_display_name":"Wellcome Trust"}],"funders":[{"id":"https://openalex.org/F4320307758","display_name":"Eli Lilly and Company","ror":"https://ror.org/01qat3289"},{"id":"https://openalex.org/F4320307765","display_name":"Pfizer","ror":"https://ror.org/01xdqrp08"},{"id":"https://openalex.org/F4320307773","display_name":"GlaxoSmithKline","ror":"https://ror.org/01xsqw823"},{"id":"https://openalex.org/F4320311198","display_name":"South London and Maudsley NHS Foundation Trust","ror":"https://ror.org/015803449"},{"id":"https://openalex.org/F4320311440","display_name":"National Alliance for Research on Schizophrenia and Depression","ror":"https://ror.org/03a63f080"},{"id":"https://openalex.org/F4320311904","display_name":"Wellcome Trust","ror":"https://ror.org/029chgv08"},{"id":"https://openalex.org/F4320314707","display_name":"Government of the United Kingdom","ror":"https://ror.org/05wnh3t63"},{"id":"https://openalex.org/F4320314731","display_name":"UK Research and Innovation","ror":"https://ror.org/001aqnf71"},{"id":"https://openalex.org/F4320316428","display_name":"Psychiatry Research Trust","ror":"https://ror.org/01ywejq18"},{"id":"https://openalex.org/F4320319990","display_name":"National Institute for Health and Care Research","ror":"https://ror.org/0187kwz08"},{"id":"https://openalex.org/F4320320285","display_name":"King's College London","ror":"https://ror.org/0220mzb33"},{"id":"https://openalex.org/F4320320300","display_name":"European Commission","ror":"https://ror.org/00k4n6c32"},{"id":"https://openalex.org/F4320320360","display_name":"University of Bristol","ror":"https://ror.org/0524sp257"},{"id":"https://openalex.org/F4320321007","display_name":"ZonMw","ror":"https://ror.org/01yaj9a77"},{"id":"https://openalex.org/F4320321009","display_name":"Erasmus Universiteit Rotterdam","ror":"https://ror.org/057w15z03"},{"id":"https://openalex.org/F4320321645","display_name":"Ministerie van Volksgezondheid, Welzijn en Sport","ror":"https://ror.org/041evnj42"},{"id":"https://openalex.org/F4320321687","display_name":"Erasmus Medisch Centrum","ror":"https://ror.org/018906e22"},{"id":"https://openalex.org/F4320327918","display_name":"H. Lundbeck A/S","ror":"https://ror.org/0564cd633"},{"id":"https://openalex.org/F4320332999","display_name":"Horizon 2020 Framework Programme","ror":"https://ror.org/00k4n6c32"},{"id":"https://openalex.org/F4320333687","display_name":"Manchester Biomedical Research Centre","ror":"https://ror.org/05njkjr15"},{"id":"https://openalex.org/F4320334322","display_name":"HORIZON EUROPE Framework Programme","ror":null},{"id":"https://openalex.org/F4320334626","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517"},{"id":"https://openalex.org/F4320334678","display_name":"European Research Council","ror":"https://ror.org/0472cxd90"},{"id":"https://openalex.org/F4320336039","display_name":"NIHR Imperial Biomedical Research Centre","ror":"https://ror.org/01kmhx639"},{"id":"https://openalex.org/F4320337601","display_name":"Janssen Pharmaceuticals","ror":"https://ror.org/03qd7mz70"},{"id":"https://openalex.org/F4320338335","display_name":"H2020 European Research Council","ror":"https://ror.org/0472cxd90"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4384025716.pdf","grobid_xml":"https://content.openalex.org/works/W4384025716.grobid-xml"},"referenced_works_count":40,"referenced_works":["https://openalex.org/W119439119","https://openalex.org/W1653360437","https://openalex.org/W1857560301","https://openalex.org/W1923413190","https://openalex.org/W1932148202","https://openalex.org/W2009311733","https://openalex.org/W2025802167","https://openalex.org/W2026340830","https://openalex.org/W2030983312","https://openalex.org/W2045383447","https://openalex.org/W2098045350","https://openalex.org/W2114949397","https://openalex.org/W2123263006","https://openalex.org/W2127484731","https://openalex.org/W2127960841","https://openalex.org/W2138884119","https://openalex.org/W2143509157","https://openalex.org/W2143625779","https://openalex.org/W2230117712","https://openalex.org/W2276786836","https://openalex.org/W2530860598","https://openalex.org/W2537951518","https://openalex.org/W2557643468","https://openalex.org/W2605192266","https://openalex.org/W2606173674","https://openalex.org/W2611955171","https://openalex.org/W2739853256","https://openalex.org/W2809993608","https://openalex.org/W2811190164","https://openalex.org/W2887580542","https://openalex.org/W2901500865","https://openalex.org/W2907476182","https://openalex.org/W2962724005","https://openalex.org/W3214856856","https://openalex.org/W4205629579","https://openalex.org/W4210761116","https://openalex.org/W4254913758","https://openalex.org/W4285085247","https://openalex.org/W4292229870","https://openalex.org/W6604788643"],"related_works":["https://openalex.org/W2534980785","https://openalex.org/W4401921103","https://openalex.org/W3135497764","https://openalex.org/W2491000634","https://openalex.org/W2982110472","https://openalex.org/W2612731643","https://openalex.org/W2773918219","https://openalex.org/W7061220311","https://openalex.org/W2039049656","https://openalex.org/W1990677879"],"abstract_inverted_index":{"OBJECTIVE:":[0],"Depression":[1],"and":[2,8,23,53,102,130,140,154,191,210,231,265,361],"obesity":[3,24],"are":[4],"2":[5,67,73],"highly":[6],"prevalent":[7],"often":[9],"comorbid":[10],"conditions.":[11,68],"Exposure":[12],"to":[13,106,247,262,276,293,358],"early-life":[14],"stress":[15,48,156,190,215],"(ELS)":[16],"has":[17],"been":[18],"associated":[19,164,217],"with":[20,165,169,218],"both":[21],"depression":[22],"in":[25,240,268,285,301,328,353,364],"adulthood,":[26],"as":[27,29,134,315,340],"well":[28],"their":[30,131],"preclinical":[31],"manifestations":[32],"during":[33],"development.":[34],"However,":[35],"it":[36],"remains":[37],"unclear":[38],"whether":[39,54],"(1)":[40],"associations":[41,251],"differ":[42],"depending":[43],"on":[44,237],"the":[45,63,66,116,135,269,286,296,309,334],"timing":[46,230],"of":[47,98,137,171,176,222,229,235,271,283,288,308,311,318,333,336,343],"exposure":[49],"(prenatal":[50],"vs":[51],"postnatal),":[52],"(2)":[55],"ELS":[56,236],"is":[57,245],"a":[58,172,316,341],"shared":[59,232],"risk":[60,221],"factor":[61],"underlying":[62],"comorbidity":[64],"between":[65,189],"METHOD:":[69],"Leveraging":[70],"data":[71],"from":[72],"large":[74],"population-based":[75],"birth":[76,105],"cohorts":[77],"(ALSPAC:":[78],"n":[79,87],"=":[80,88,150,159,206],"8,428":[81],"[52%":[82],"male":[83,91],"participants];":[84],"Generation":[85],"R:":[86],"4,268":[89],"[48%":[90],"participants]),":[92],"we":[93,114],"constructed":[94],"comprehensive":[95],"cumulative":[96],"measures":[97],"prenatal":[99,145,185,202],"(in":[100],"utero)":[101],"postnatal":[103,155,177,211],"(from":[104],"10":[107],"years)":[108],"ELS.":[109],"At":[110],"age":[111],"13.5":[112],"years,":[113],"assessed":[115],"following:":[117],"internalizing":[118,139,167],"symptoms":[119],"(using":[120,126],"maternal":[121],"reports);":[122],"fat":[123],"mass":[124],"percentage":[125],"dual-energy":[127],"X-ray":[128],"absorptiometry);":[129],"comorbidity,":[132],"defined":[133],"co-occurrence":[136],"high":[138,141],"adiposity.":[142],"RESULTS:":[143],"Both":[144,201],"(total":[146],"effect":[147],"[95%":[148],"CI]":[149],"0.20":[151],"[0.16;":[152],"0.22])":[153],"(\u03b2":[157],"[95%CI]":[158,205],"0.22":[160],"[0.17;":[161],"0.25])":[162],"were":[163,216,299],"higher":[166],"symptoms,":[168],"evidence":[170,228],"more":[173,307,321,332,346],"prominent":[174],"role":[175],"stress.":[178],"A":[179],"weaker":[180],"association":[181],"(driven":[182],"primarily":[183],"by":[184],"stress)":[186],"was":[187],"observed":[188],"adiposity":[192],"(prenatal:":[193],"0.07":[194],"[0.05;":[195],"0.09];":[196],"postnatal:":[197],"0.04":[198],"[0.01;":[199],"0.07]).":[200],"(odds":[203],"ratio":[204],"1.70":[207],"[1.47;":[208],"1.97])":[209],"(1.87":[212],"[1.61;":[213],"2.17])":[214],"an":[219,302],"increased":[220],"developing":[223],"comorbidity.":[224],"CONCLUSION:":[225],"We":[226,260,274,291,355],"found":[227],"causal":[233],"effects":[234],"psycho-cardiometabolic":[238],"health":[239],"adolescence;":[241],"however,":[242],"future":[243],"research":[244],"warranted":[246],"clarify":[248],"how":[249],"these":[250],"may":[252],"unfold":[253],"over":[254],"time.":[255],"DIVERSITY":[256],"&":[257],"INCLUSION":[258],"STATEMENT:":[259],"worked":[261,275,292,357],"ensure":[263,277,294],"sex":[264,360],"gender":[266,351,362],"balance":[267,363],"recruitment":[270,287],"human":[272,289],"participants.":[273,290],"race,":[278],"ethnic,":[279],"and/or":[280,325,350],"other":[281],"types":[282],"diversity":[284],"that":[295],"study":[297],"questionnaires":[298],"prepared":[300],"inclusive":[303],"way.":[304],"One":[305,330],"or":[306,320,331,345],"authors":[310,335],"this":[312,337],"paper":[313,338],"self-identifies":[314,339],"member":[317,342],"one":[319,344],"historically":[322,347],"underrepresented":[323,348],"racial":[324],"ethnic":[326],"groups":[327,352],"science.":[329,354],"sexual":[349],"actively":[356],"promote":[359],"our":[365],"author":[366],"group.":[367]},"counts_by_year":[{"year":2026,"cited_by_count":5},{"year":2025,"cited_by_count":8},{"year":2024,"cited_by_count":3}],"updated_date":"2026-11-03T10:50:19.383937","created_date":"2023-07-13T00:00:00"}