{"id":"https://openalex.org/W4383872025","doi":"https://doi.org/10.1007/s00285-023-01962-0","title":"Algorithmic criteria for the validity of quasi-steady state and partial equilibrium models: the Michaelis\u2013Menten reaction mechanism","display_name":"Algorithmic criteria for the validity of quasi-steady state and partial equilibrium models: the Michaelis\u2013Menten reaction mechanism","publication_year":2023,"publication_date":"2023-07-11","ids":{"openalex":"https://openalex.org/W4383872025","doi":"https://doi.org/10.1007/s00285-023-01962-0","pmid":"https://pubmed.ncbi.nlm.nih.gov/37432484"},"language":"en","primary_location":{"id":"doi:10.1007/s00285-023-01962-0","doi":"https://doi.org/10.1007/s00285-023-01962-0","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s00285-023-01962-0","pdf_url":null,"source":{"id":"https://openalex.org/S171842551","display_name":"Journal of Mathematical Biology","issn_l":"0303-6812","issn":["0303-6812","1432-1416"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-1","medline","norway-2","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Mathematical Biology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5050060748","display_name":"Dimitrios G. Patsatzis","orcid":"https://orcid.org/0000-0001-9840-0018","observed_orcids":["https://orcid.org/0000-0001-9840-0018"]},"institutions":[{"id":"https://openalex.org/I174458059","display_name":"National Technical University of Athens","ror":"https://ror.org/03cx6bg69","country_code":"GR","type":"education","lineage":["https://openalex.org/I174458059"]},{"id":"https://openalex.org/I4210155236","display_name":"National Research Council","ror":"https://ror.org/04zaypm56","country_code":"IT","type":"nonprofit","lineage":["https://openalex.org/I4210155236"]}],"countries":["GR","IT"],"is_corresponding":false,"raw_author_name":"Dimitris G. Patsatzis","raw_affiliation_strings":["Department of Applied Mathematics and Physical Sciences, National Technical University of Athens, 15773, Athens, Greece","Department of Science and Technology for Energy and Sustainable Mobility, Consiglio Nazionale delle Ricerche, 80125, Naples, Italy"],"raw_orcid":"https://orcid.org/0000-0001-9840-0018","affiliations":[{"raw_affiliation_string":"Department of Applied Mathematics and Physical Sciences, National Technical University of Athens, 15773, Athens, Greece","institution_ids":["https://openalex.org/I174458059"]},{"raw_affiliation_string":"Department of Science and Technology for Energy and Sustainable Mobility, Consiglio Nazionale delle Ricerche, 80125, Naples, Italy","institution_ids":["https://openalex.org/I4210155236"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5030085333","display_name":"Dimitris A. Goussis","orcid":"https://orcid.org/0000-0002-9674-9491","observed_orcids":["https://orcid.org/0000-0002-9674-9491"]},"institutions":[{"id":"https://openalex.org/I176601375","display_name":"Khalifa University of Science and Technology","ror":"https://ror.org/05hffr360","country_code":"AE","type":"education","lineage":["https://openalex.org/I176601375"]}],"countries":["AE"],"is_corresponding":true,"raw_author_name":"Dimitris A. Goussis","raw_affiliation_strings":["Department of Mechanical Engineering, Khalifa University of Science and Technology, 127788, Abu Dhabi, UAE. dimitris.goussis@ku.ac.ae","Department of Mechanical Engineering, Khalifa University of Science and Technology, 127788, Abu Dhabi, UAE"],"raw_orcid":"https://orcid.org/0000-0002-9674-9491","affiliations":[{"raw_affiliation_string":"Department of Mechanical Engineering, Khalifa University of Science and Technology, 127788, Abu Dhabi, UAE. dimitris.goussis@ku.ac.ae","institution_ids":["https://openalex.org/I176601375"]},{"raw_affiliation_string":"Department of Mechanical Engineering, Khalifa University of Science and Technology, 127788, Abu Dhabi, UAE","institution_ids":["https://openalex.org/I176601375"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5030085333"],"corresponding_institution_ids":["https://openalex.org/I176601375"],"apc_list":{"value":2790,"currency":"USD","value_usd":2790},"apc_paid":null,"fwci":2.0996,"has_fulltext":false,"cited_by_count":11,"citation_normalized_percentile":{"value":0.86619933,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"87","issue":"2","first_page":"27","last_page":"27"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12727","display_name":"Singular Perturbation, Asymptotics and Difference Schemes","score":0.40549999475479126,"subfield":{"id":"https://openalex.org/subfields/2612","display_name":"Numerical Analysis"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T12727","display_name":"Singular Perturbation, Asymptotics and Difference Schemes","score":0.40549999475479126,"subfield":{"id":"https://openalex.org/subfields/2612","display_name":"Numerical Analysis"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11206","display_name":"Model Reduction and Neural Networks","score":0.3774000108242035,"subfield":{"id":"https://openalex.org/subfields/3109","display_name":"Statistical and Nonlinear Physics"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12100","display_name":"Advanced Mathematical Modeling in Engineering","score":0.04390000179409981,"subfield":{"id":"https://openalex.org/subfields/2604","display_name":"Applied Mathematics"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/quasi-steady-state-approximation","display_name":"quasi-steady-state approximation","score":0.968999981880188},{"id":"https://openalex.org/keywords/model-reduction","display_name":"model reduction","score":0.8569999933242798},{"id":"https://openalex.org/keywords/accuracy-criteria","display_name":"accuracy criteria","score":0.6570000052452087},{"id":"https://openalex.org/keywords/fast-time-scale","display_name":"fast time scale","score":0.8109999895095825},{"id":"https://openalex.org/keywords/tangent-space","display_name":"tangent space","score":0.593999981880188},{"id":"https://openalex.org/keywords/reaction-kinetics","display_name":"reaction kinetics","score":0.37599998712539673}],"concepts":[{"id":"https://openalex.org/C8171440","wikidata":"https://www.wikidata.org/wiki/Q903414","display_name":"Steady state (chemistry)","level":2,"score":0.5293237566947937},{"id":"https://openalex.org/C89611455","wikidata":"https://www.wikidata.org/wiki/Q6804646","display_name":"Mechanism (biology)","level":2,"score":0.5137796998023987},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.4977748692035675},{"id":"https://openalex.org/C28826006","wikidata":"https://www.wikidata.org/wiki/Q33521","display_name":"Applied mathematics","level":1,"score":0.48724666237831116},{"id":"https://openalex.org/C64915919","wikidata":"https://www.wikidata.org/wiki/Q613955","display_name":"Michaelis\u2013Menten kinetics","level":4,"score":0.4515310227870941},{"id":"https://openalex.org/C144237770","wikidata":"https://www.wikidata.org/wiki/Q747534","display_name":"Mathematical economics","level":1,"score":0.4329182207584381},{"id":"https://openalex.org/C121864883","wikidata":"https://www.wikidata.org/wiki/Q677916","display_name":"Statistical physics","level":1,"score":0.3967565894126892},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.22740381956100464},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.2213301658630371},{"id":"https://openalex.org/C147789679","wikidata":"https://www.wikidata.org/wiki/Q11372","display_name":"Physical chemistry","level":1,"score":0.10228732228279114},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C46141821","wikidata":"https://www.wikidata.org/wiki/Q209402","display_name":"Nuclear magnetic resonance","level":1,"score":0.0},{"id":"https://openalex.org/C28212737","wikidata":"https://www.wikidata.org/wiki/Q5381543","display_name":"Enzyme assay","level":3,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1007/s00285-023-01962-0","doi":"https://doi.org/10.1007/s00285-023-01962-0","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s00285-023-01962-0","pdf_url":null,"source":{"id":"https://openalex.org/S171842551","display_name":"Journal of Mathematical Biology","issn_l":"0303-6812","issn":["0303-6812","1432-1416"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-1","medline","norway-2","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Mathematical Biology","raw_type":"journal-article"},{"id":"pmid:37432484","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37432484","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of mathematical biology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G8243796244","display_name":null,"funder_award_id":"2212/2016","funder_id":"https://openalex.org/F4320331138","funder_display_name":"Eugenides Foundation"}],"funders":[{"id":"https://openalex.org/F4320331138","display_name":"Eugenides Foundation","ror":"https://ror.org/014bb9017"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":86,"referenced_works":["https://openalex.org/W152317225","https://openalex.org/W179936242","https://openalex.org/W197577667","https://openalex.org/W200565028","https://openalex.org/W420509224","https://openalex.org/W587121583","https://openalex.org/W1581063030","https://openalex.org/W1608234917","https://openalex.org/W1869042642","https://openalex.org/W1884432551","https://openalex.org/W1959732153","https://openalex.org/W1966113499","https://openalex.org/W1975553365","https://openalex.org/W1980085157","https://openalex.org/W1984739430","https://openalex.org/W1991418841","https://openalex.org/W1992179397","https://openalex.org/W1994500037","https://openalex.org/W1996405985","https://openalex.org/W1997508985","https://openalex.org/W1997586090","https://openalex.org/W1998842497","https://openalex.org/W1999028875","https://openalex.org/W2001698066","https://openalex.org/W2002162541","https://openalex.org/W2002164453","https://openalex.org/W2004094140","https://openalex.org/W2006139156","https://openalex.org/W2008949725","https://openalex.org/W2015826854","https://openalex.org/W2016767879","https://openalex.org/W2019685954","https://openalex.org/W2021844372","https://openalex.org/W2024283669","https://openalex.org/W2027571621","https://openalex.org/W2030955594","https://openalex.org/W2032701031","https://openalex.org/W2034312218","https://openalex.org/W2037999126","https://openalex.org/W2041210714","https://openalex.org/W2044484168","https://openalex.org/W2049020763","https://openalex.org/W2050306906","https://openalex.org/W2056372659","https://openalex.org/W2058343991","https://openalex.org/W2062474993","https://openalex.org/W2062856462","https://openalex.org/W2066530583","https://openalex.org/W2067184822","https://openalex.org/W2072480667","https://openalex.org/W2073229378","https://openalex.org/W2075835338","https://openalex.org/W2077255563","https://openalex.org/W2084511933","https://openalex.org/W2086387602","https://openalex.org/W2089631607","https://openalex.org/W2091928541","https://openalex.org/W2095889937","https://openalex.org/W2096605014","https://openalex.org/W2105736780","https://openalex.org/W2125979692","https://openalex.org/W2129251513","https://openalex.org/W2138221986","https://openalex.org/W2138278836","https://openalex.org/W2139882086","https://openalex.org/W2153901189","https://openalex.org/W2154882140","https://openalex.org/W2155972438","https://openalex.org/W2159287491","https://openalex.org/W2161317287","https://openalex.org/W2167635580","https://openalex.org/W2324834169","https://openalex.org/W2591853258","https://openalex.org/W2802846012","https://openalex.org/W2808830890","https://openalex.org/W2949881672","https://openalex.org/W2952255773","https://openalex.org/W2956013039","https://openalex.org/W2995674602","https://openalex.org/W3181422811","https://openalex.org/W3184757832","https://openalex.org/W4214947946","https://openalex.org/W4224005609","https://openalex.org/W4236765228","https://openalex.org/W4239981491","https://openalex.org/W4252247111"],"related_works":["https://openalex.org/W4410430387","https://openalex.org/W4225856899","https://openalex.org/W4392190447","https://openalex.org/W4391923235","https://openalex.org/W2050306906","https://openalex.org/W3214775959","https://openalex.org/W3059301586","https://openalex.org/W4220713866","https://openalex.org/W2129251513","https://openalex.org/W2044431968"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":1}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2023-07-12T00:00:00"}
