{"id":"https://openalex.org/W4383703962","doi":"https://doi.org/10.17826/cumj.1239938","title":"Monitoring of cytomegalovirus, Epstein-Barr virus and adenovirus infections in hematopoietic stem cell transplant recipients","display_name":"Monitoring of cytomegalovirus, Epstein-Barr virus and adenovirus infections in hematopoietic stem cell transplant recipients","publication_year":2023,"publication_date":"2023-07-02","ids":{"openalex":"https://openalex.org/W4383703962","doi":"https://doi.org/10.17826/cumj.1239938"},"language":"en","primary_location":{"id":"doi:10.17826/cumj.1239938","doi":"https://doi.org/10.17826/cumj.1239938","is_oa":true,"landing_page_url":"http://dx.doi.org/10.17826/cumj.1239938","pdf_url":"https://dergipark.org.tr/en/download/article-file/2907199","source":{"id":"https://openalex.org/S2736940880","display_name":"C\u0327ukurova medical journal (Online)/C\u0327ukurova medical journal","issn_l":"2602-3032","issn":["2602-3032","2602-3040"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":["dongbi-d","poland-20","russia-white-list-4","tr-dizin"],"host_organization":"https://openalex.org/P4310318373","host_organization_name":"\u00c7ukurova University","host_organization_lineage":["https://openalex.org/P4310318373"],"host_organization_lineage_names":["\u00c7ukurova University"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cukurova Medical Journal","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://dergipark.org.tr/en/download/article-file/2907199","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5018685015","display_name":"Buket \u015eeflek","orcid":"https://orcid.org/0000-0002-0923-4407","observed_orcids":["https://orcid.org/0000-0002-0923-4407"]},"institutions":[{"id":"https://openalex.org/I55931168","display_name":"Cukurova University","ror":"https://ror.org/05wxkj555","country_code":"TR","type":"education","lineage":["https://openalex.org/I55931168"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Buket \u015eEFLEK","raw_affiliation_strings":["\u00c7UKUROVA \u00dcN\u0130VERS\u0130TES\u0130"],"raw_orcid":"https://orcid.org/0000-0002-0923-4407","affiliations":[{"raw_affiliation_string":"\u00c7UKUROVA \u00dcN\u0130VERS\u0130TES\u0130","institution_ids":["https://openalex.org/I55931168"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Hale G\u00dcM\u00dc\u015e","orcid":"https://orcid.org/0000-0001-9071-9606","observed_orcids":["https://orcid.org/0000-0001-9071-9606"]},"institutions":[{"id":"https://openalex.org/I55931168","display_name":"Cukurova University","ror":"https://ror.org/05wxkj555","country_code":"TR","type":"education","lineage":["https://openalex.org/I55931168"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Hale G\u00dcM\u00dc\u015e","raw_affiliation_strings":["\u00c7UKUROVA \u00dcN\u0130VERS\u0130TES\u0130"],"raw_orcid":"https://orcid.org/0000-0001-9071-9606","affiliations":[{"raw_affiliation_string":"\u00c7UKUROVA \u00dcN\u0130VERS\u0130TES\u0130","institution_ids":["https://openalex.org/I55931168"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002089320","display_name":"Mehmet \u00c7imentepe","orcid":"https://orcid.org/0000-0002-3563-2468","observed_orcids":["https://orcid.org/0000-0002-3563-2468"]},"institutions":[{"id":"https://openalex.org/I55931168","display_name":"Cukurova University","ror":"https://ror.org/05wxkj555","country_code":"TR","type":"education","lineage":["https://openalex.org/I55931168"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Mehmet \u00c7\u0130MENTEPE","raw_affiliation_strings":["\u00c7UKUROVA \u00dcN\u0130VERS\u0130TES\u0130"],"raw_orcid":"https://orcid.org/0000-0002-3563-2468","affiliations":[{"raw_affiliation_string":"\u00c7UKUROVA \u00dcN\u0130VERS\u0130TES\u0130","institution_ids":["https://openalex.org/I55931168"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021869952","display_name":"Serhan K\u00fcpeli","orcid":"https://orcid.org/0000-0001-7271-1803","observed_orcids":["https://orcid.org/0000-0001-7271-1803"]},"institutions":[{"id":"https://openalex.org/I55931168","display_name":"Cukurova University","ror":"https://ror.org/05wxkj555","country_code":"TR","type":"education","lineage":["https://openalex.org/I55931168"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Serhan K\u00dcPEL\u0130","raw_affiliation_strings":["\u00c7UKUROVA \u00dcN\u0130VERS\u0130TES\u0130"],"raw_orcid":"https://orcid.org/0000-0001-7271-1803","affiliations":[{"raw_affiliation_string":"\u00c7UKUROVA \u00dcN\u0130VERS\u0130TES\u0130","institution_ids":["https://openalex.org/I55931168"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5076298248","display_name":"F\u00fcgen Yark\u0131n","orcid":"https://orcid.org/0000-0002-6012-2320","observed_orcids":["https://orcid.org/0000-0002-6012-2320"]},"institutions":[{"id":"https://openalex.org/I55931168","display_name":"Cukurova University","ror":"https://ror.org/05wxkj555","country_code":"TR","type":"education","lineage":["https://openalex.org/I55931168"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"F\u00fcgen YARKIN","raw_affiliation_strings":["\u00c7UKUROVA \u00dcN\u0130VERS\u0130TES\u0130"],"raw_orcid":"https://orcid.org/0000-0002-6012-2320","affiliations":[{"raw_affiliation_string":"\u00c7UKUROVA \u00dcN\u0130VERS\u0130TES\u0130","institution_ids":["https://openalex.org/I55931168"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I55931168"],"apc_list":null,"apc_paid":null,"fwci":0.3887,"has_fulltext":true,"cited_by_count":2,"citation_normalized_percentile":{"value":0.57593953,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":95},"biblio":{"volume":"48","issue":"2","first_page":"432","last_page":"440"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10981","display_name":"Cytomegalovirus and herpesvirus research","score":0.9926999807357788,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10981","display_name":"Cytomegalovirus and herpesvirus research","score":0.9926999807357788,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10685","display_name":"Viral-associated cancers and disorders","score":0.005400000140070915,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10345","display_name":"Hematopoietic Stem Cell Transplantation","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cytomegalovirus-infection","display_name":"cytomegalovirus infection","score":0.9509999752044678},{"id":"https://openalex.org/keywords/epstein-barr-virus-infection","display_name":"Epstein-Barr virus infection","score":0.9940000176429749},{"id":"https://openalex.org/keywords/adenovirus-infection","display_name":"adenovirus infection","score":1.0},{"id":"https://openalex.org/keywords/hematopoietic-stem-cell-transplantation","display_name":"hematopoietic stem cell transplantation","score":0.9829999804496765},{"id":"https://openalex.org/keywords/viral-infection-surveillance","display_name":"viral infection surveillance","score":0.5130000114440918},{"id":"https://openalex.org/keywords/preemptive-antiviral-therapy","display_name":"preemptive antiviral therapy","score":0.8399999737739563},{"id":"https://openalex.org/keywords/allogeneic-transplantation","display_name":"allogeneic transplantation","score":0.7099999785423279},{"id":"https://openalex.org/keywords/autologous-transplantation","display_name":"autologous transplantation","score":0.9980000257492065},{"id":"https://openalex.org/keywords/pediatric-transplant-recipients","display_name":"pediatric transplant recipients","score":0.7110000252723694},{"id":"https://openalex.org/keywords/viral-load","display_name":"viral load","score":0.5379999876022339},{"id":"https://openalex.org/keywords/seroprevalence","display_name":"seroprevalence","score":0.722000002861023},{"id":"https://openalex.org/keywords/immunosuppression","display_name":"immunosuppression","score":0.7670000195503235}],"concepts":[{"id":"https://openalex.org/C2777408962","wikidata":"https://www.wikidata.org/wiki/Q1128050","display_name":"Hematopoietic stem cell transplantation","level":3,"score":0.7140921354293823},{"id":"https://openalex.org/C2777732132","wikidata":"https://www.wikidata.org/wiki/Q6946","display_name":"Cytomegalovirus","level":5,"score":0.7106429934501648},{"id":"https://openalex.org/C2780252810","wikidata":"https://www.wikidata.org/wiki/Q1455316","display_name":"Immunosuppression","level":2,"score":0.6384093761444092},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6381031274795532},{"id":"https://openalex.org/C2911091166","wikidata":"https://www.wikidata.org/wiki/Q106419912","display_name":"Transplantation","level":2,"score":0.5127938389778137},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.5019140243530273},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.4612087309360504},{"id":"https://openalex.org/C142462285","wikidata":"https://www.wikidata.org/wiki/Q2528140","display_name":"Viral load","level":3,"score":0.4382932782173157},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4128355085849762},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.4014943838119507},{"id":"https://openalex.org/C2776409557","wikidata":"https://www.wikidata.org/wiki/Q149348","display_name":"Herpesviridae","level":4,"score":0.37533432245254517},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.3322165012359619},{"id":"https://openalex.org/C2780727368","wikidata":"https://www.wikidata.org/wiki/Q1928978","display_name":"Viral disease","level":3,"score":0.2377578616142273}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.17826/cumj.1239938","doi":"https://doi.org/10.17826/cumj.1239938","is_oa":true,"landing_page_url":"http://dx.doi.org/10.17826/cumj.1239938","pdf_url":"https://dergipark.org.tr/en/download/article-file/2907199","source":{"id":"https://openalex.org/S2736940880","display_name":"C\u0327ukurova medical journal (Online)/C\u0327ukurova medical journal","issn_l":"2602-3032","issn":["2602-3032","2602-3040"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":["dongbi-d","poland-20","russia-white-list-4","tr-dizin"],"host_organization":"https://openalex.org/P4310318373","host_organization_name":"\u00c7ukurova University","host_organization_lineage":["https://openalex.org/P4310318373"],"host_organization_lineage_names":["\u00c7ukurova University"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cukurova Medical Journal","raw_type":"journal-article"},{"id":"pmh:oai:dergipark.org.tr:article/1239938","doi":null,"is_oa":true,"landing_page_url":"https://dergipark.org.tr/tr/pub/cumj/issue/76399/1239938","pdf_url":"https://dergipark.org.tr/tr/download/article-file/2907199","source":{"id":"https://openalex.org/S4306401840","display_name":"DergiPark (Istanbul University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I67581229","host_organization_name":"Istanbul University","host_organization_lineage":["https://openalex.org/I67581229"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Cukurova Medical Journal","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.17826/cumj.1239938","doi":"https://doi.org/10.17826/cumj.1239938","is_oa":true,"landing_page_url":"http://dx.doi.org/10.17826/cumj.1239938","pdf_url":"https://dergipark.org.tr/en/download/article-file/2907199","source":{"id":"https://openalex.org/S2736940880","display_name":"C\u0327ukurova medical journal (Online)/C\u0327ukurova medical journal","issn_l":"2602-3032","issn":["2602-3032","2602-3040"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":["dongbi-d","poland-20","russia-white-list-4","tr-dizin"],"host_organization":"https://openalex.org/P4310318373","host_organization_name":"\u00c7ukurova University","host_organization_lineage":["https://openalex.org/P4310318373"],"host_organization_lineage_names":["\u00c7ukurova University"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cukurova Medical Journal","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[{"id":"https://openalex.org/G7039450079","display_name":null,"funder_award_id":"TF2013D4","funder_id":"https://openalex.org/F4320321619","funder_display_name":"\u00c7ukurova \u00dcniversitesi"}],"funders":[{"id":"https://openalex.org/F4320321619","display_name":"\u00c7ukurova \u00dcniversitesi","ror":"https://ror.org/05wxkj555"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4383703962.pdf","grobid_xml":"https://content.openalex.org/works/W4383703962.grobid-xml"},"referenced_works_count":22,"referenced_works":["https://openalex.org/W129120702","https://openalex.org/W1634615148","https://openalex.org/W1978481681","https://openalex.org/W2045604259","https://openalex.org/W2104600694","https://openalex.org/W2158138034","https://openalex.org/W2552258289","https://openalex.org/W2572190179","https://openalex.org/W2939764681","https://openalex.org/W2951105925","https://openalex.org/W2971171470","https://openalex.org/W3005426886","https://openalex.org/W3093106731","https://openalex.org/W3104992153","https://openalex.org/W3121570388","https://openalex.org/W3135864954","https://openalex.org/W3164903470","https://openalex.org/W3169095078","https://openalex.org/W3174633785","https://openalex.org/W4205422762","https://openalex.org/W4211131502","https://openalex.org/W4292582459"],"related_works":["https://openalex.org/W2809669846","https://openalex.org/W2939764681","https://openalex.org/W2025896312","https://openalex.org/W2036200124","https://openalex.org/W1994128668","https://openalex.org/W2564521859","https://openalex.org/W2597003838","https://openalex.org/W2378628585","https://openalex.org/W1991654780","https://openalex.org/W2007631295"],"abstract_inverted_index":{"Purpose:":[0],"Haematopoietic":[1],"stem":[2],"cell":[3],"transplant":[4],"(HSCT)":[5],"recipients":[6,131],"with":[7,188,194],"iatrogenic":[8],"immunosuppression":[9],"are":[10],"high-risk":[11],"patients":[12,46,116,301],"for":[13,65,80,97,205],"viral":[14,177,259,285,291,297],"infections.":[15],"The":[16,70],"aim":[17],"of":[18,26,183,252,258,290,296,314],"this":[19,173],"study":[20],"was":[21,72,99,141,197,203,215,231,261],"to":[22,89,134,233,284],"investigate":[23],"the":[24,81,256,271],"incidence":[25],"cytomegalovirus":[27],"(CMV),":[28],"Epstein-Barr":[29],"virus":[30],"(EBV),":[31],"and":[32,40,54,68,78,159,191,224,248,308],"adenovirus":[33],"(ADV)":[34],"infections":[35,292],"in":[36,143,152,162,179,217,222,227,263,299,305],"HSCT":[37,57,77,119,130,170,211,300],"recipients.":[38],"Materials":[39],"Methods:":[41],"We":[42],"prospectively":[43],"monitored":[44],"35":[45,114,253,273],"aged":[47],"0-17":[48],"years":[49],"who":[50,117],"had":[51],"allogeneic":[52,169],"(n=30)":[53],"autologous":[55,210],"(n=5)":[56],"by":[58,101,293,310],"quantitative":[59],"real-time":[60],"polymerase":[61],"chain":[62],"reaction":[63],"tests":[64],"CMV,":[66,241],"EBV,":[67,243],"ADV.":[69],"monitoring":[71,295],"performed":[73],"one":[74,90,185,192],"week":[75,107],"before":[76,108],"weekly":[79],"first":[82],"100":[83],"days,":[84],"once":[85],"a":[86,106],"month":[87],"up":[88],"year":[91],"after":[92],"HSCT.":[93],"In":[94,172],"addition,":[95],"seropositivity":[96],"viruses":[98],"analysed":[100],"Enzyme-Linked":[102],"Immuno":[103],"Sorbent":[104],"Assay":[105],"transplantation.":[109],"Results:":[110],"Before":[111],"transplantation,":[112],"all":[113],"(100%)":[115],"underwent":[118],"were":[120,132],"CMV":[121,139,175,213],"IgG":[122,137],"positive,":[123],"30":[124],"(85.7%":[125],"-":[126,146,155,165,236,266,278],"95%":[127,147,156,166,237,267,279],"CI:":[128,148,157,167,238,268,280],"74.1%-97.3%)":[129],"found":[133,142],"be":[135,303],"EBV":[136,160,189,220],"positive.":[138],"infection":[140,151,161],"24":[144],"(80%":[145],"65.7%-94.3%),":[149],"ADV":[150,195,225],"11":[153,234],"(36.7%":[154],"19.4%-53.9%)":[158],"8":[163,180],"(26.7%":[164],"10.8%-42.5%)":[168],"patients.":[171,254],"group,":[174],"DNA":[176,190,214,221,226],"load":[178],"(26.7%)":[181],"patients,":[182,219,274],"which":[184,202],"(3.3%)":[186,193],"coinfected":[187],"DNA,":[196],"higher":[198],"than":[199],"1000":[200],"copies/mL":[201],"required":[204],"pre-emptive":[206,315],"treatment.":[207],"Among":[208],"5":[209,223],"recipients,":[212],"detected":[216],"2":[218,242,276],"2.":[228],"Pre-emptive":[229],"treatment":[230],"given":[232],"(%31.4":[235],"16%-46.8%;":[239],"6":[240],"1":[244,246,249],"ADV,":[245],"CMV-EBV":[247],"CMV-ADV":[250],"infection)":[251],"Thus,":[255],"development":[257],"disease":[260],"prevented":[262],"7":[264],"(63.6%":[265],"35.2%-92.1%).":[269],"Of":[270],"total":[272],"only":[275],"(5.7%":[277],"0.0%-13.4%)":[281],"died":[282],"due":[283],"infection.":[286],"Conclusion:":[287],"Early":[288],"diagnosis":[289],"prospective":[294],"loads":[298],"would":[302],"effective":[304],"preventing":[306],"morbidity":[307],"mortality":[309],"ensuring":[311],"timely":[312],"initiation":[313],"therapy.":[316]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":1}],"updated_date":"2026-09-29T14:09:16.559479","created_date":"2023-07-10T00:00:00"}