{"id":"https://openalex.org/W4383620182","doi":"https://doi.org/10.1038/s41522-023-00415-2","title":"Alleviation of Limosilactobacillus reuteri in polycystic ovary syndrome protects against circadian dysrhythmia-induced dyslipidemia via capric acid and GALR1 signaling","display_name":"Alleviation of Limosilactobacillus reuteri in polycystic ovary syndrome protects against circadian dysrhythmia-induced dyslipidemia via capric acid and GALR1 signaling","publication_year":2023,"publication_date":"2023-07-08","ids":{"openalex":"https://openalex.org/W4383620182","doi":"https://doi.org/10.1038/s41522-023-00415-2","pmid":"https://pubmed.ncbi.nlm.nih.gov/37422471","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/10329655"},"language":"en","primary_location":{"id":"doi:10.1038/s41522-023-00415-2","doi":"https://doi.org/10.1038/s41522-023-00415-2","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41522-023-00415-2","pdf_url":"https://www.nature.com/articles/s41522-023-00415-2.pdf","source":{"id":"https://openalex.org/S4210229179","display_name":"npj Biofilms and Microbiomes","issn_l":"2055-5008","issn":["2055-5008"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"npj Biofilms and Microbiomes","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.nature.com/articles/s41522-023-00415-2.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100735525","display_name":"Shang Li","orcid":"https://orcid.org/0000-0003-4363-0902","observed_orcids":["https://orcid.org/0000-0003-4363-0902"]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I2800570007","display_name":"Renji Hospital","ror":"https://ror.org/03ypbx660","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2800570007"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shang Li","raw_affiliation_strings":["Center for Reproductive Medicine, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200135, China","Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Shanghai, 200135, China"],"raw_orcid":"https://orcid.org/0000-0003-4363-0902","affiliations":[{"raw_affiliation_string":"Center for Reproductive Medicine, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200135, China","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I2800570007"]},{"raw_affiliation_string":"Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Shanghai, 200135, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065250635","display_name":"Junyu Zhai","orcid":"https://orcid.org/0000-0003-3129-8084","observed_orcids":["https://orcid.org/0000-0003-3129-8084"]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I2800570007","display_name":"Renji Hospital","ror":"https://ror.org/03ypbx660","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2800570007"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Junyu Zhai","raw_affiliation_strings":["Center for Reproductive Medicine, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200135, China","Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Shanghai, 200135, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Reproductive Medicine, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200135, China","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I2800570007"]},{"raw_affiliation_string":"Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Shanghai, 200135, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049593540","display_name":"Weiwei Chu","orcid":"https://orcid.org/0000-0002-9050-8136","observed_orcids":["https://orcid.org/0000-0002-9050-8136","https://orcid.org/0009-0002-0376-2337","https://orcid.org/0009-0006-0544-5393"]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I2800570007","display_name":"Renji Hospital","ror":"https://ror.org/03ypbx660","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2800570007"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Weiwei Chu","raw_affiliation_strings":["Center for Reproductive Medicine, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200135, China","Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Shanghai, 200135, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Reproductive Medicine, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200135, China","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I2800570007"]},{"raw_affiliation_string":"Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Shanghai, 200135, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102504377","display_name":"Xueying Geng","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I2800570007","display_name":"Renji Hospital","ror":"https://ror.org/03ypbx660","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2800570007"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xueying Geng","raw_affiliation_strings":["Center for Reproductive Medicine, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200135, China","Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Shanghai, 200135, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Reproductive Medicine, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200135, China","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I2800570007"]},{"raw_affiliation_string":"Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Shanghai, 200135, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023008577","display_name":"Dongshuang Wang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I2800570007","display_name":"Renji Hospital","ror":"https://ror.org/03ypbx660","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2800570007"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Dongshuang Wang","raw_affiliation_strings":["Center for Reproductive Medicine, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200135, China","Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Shanghai, 200135, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Reproductive Medicine, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200135, China","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I2800570007"]},{"raw_affiliation_string":"Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Shanghai, 200135, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027335348","display_name":"Luwei Jiao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I2800570007","display_name":"Renji Hospital","ror":"https://ror.org/03ypbx660","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2800570007"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Luwei Jiao","raw_affiliation_strings":["Center for Reproductive Medicine, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200135, China","Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Shanghai, 200135, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Reproductive Medicine, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200135, China","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I2800570007"]},{"raw_affiliation_string":"Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Shanghai, 200135, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057444662","display_name":"Gang L\u00fc","orcid":"https://orcid.org/0000-0001-5921-1839","observed_orcids":["https://orcid.org/0000-0001-5921-1839"]},"institutions":[{"id":"https://openalex.org/I154099455","display_name":"Shandong University","ror":"https://ror.org/0207yh398","country_code":"CN","type":"education","lineage":["https://openalex.org/I154099455"]},{"id":"https://openalex.org/I177725633","display_name":"Chinese University of Hong Kong","ror":"https://ror.org/00t33hh48","country_code":"HK","type":"education","lineage":["https://openalex.org/I177725633"]}],"countries":["CN","HK"],"is_corresponding":false,"raw_author_name":"Gang Lu","raw_affiliation_strings":["The Chinese University of Hong Kong-Shandong University Joint Laboratory on Reproductive Genetics, School of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Chinese University of Hong Kong-Shandong University Joint Laboratory on Reproductive Genetics, School of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China","institution_ids":["https://openalex.org/I154099455","https://openalex.org/I177725633"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002812618","display_name":"Wai\u2010Yee Chan","orcid":"https://orcid.org/0000-0002-9714-0936","observed_orcids":["https://orcid.org/0000-0002-9714-0936"]},"institutions":[{"id":"https://openalex.org/I154099455","display_name":"Shandong University","ror":"https://ror.org/0207yh398","country_code":"CN","type":"education","lineage":["https://openalex.org/I154099455"]},{"id":"https://openalex.org/I177725633","display_name":"Chinese University of Hong Kong","ror":"https://ror.org/00t33hh48","country_code":"HK","type":"education","lineage":["https://openalex.org/I177725633"]}],"countries":["CN","HK"],"is_corresponding":false,"raw_author_name":"Wai-Yee Chan","raw_affiliation_strings":["The Chinese University of Hong Kong-Shandong University Joint Laboratory on Reproductive Genetics, School of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Chinese University of Hong Kong-Shandong University Joint Laboratory on Reproductive Genetics, School of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong SAR, China","institution_ids":["https://openalex.org/I154099455","https://openalex.org/I177725633"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074427178","display_name":"Kang Sun","orcid":"https://orcid.org/0000-0003-2727-141X","observed_orcids":["https://orcid.org/0000-0003-2727-141X"]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I2800570007","display_name":"Renji Hospital","ror":"https://ror.org/03ypbx660","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2800570007"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Kang Sun","raw_affiliation_strings":["Center for Reproductive Medicine, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200135, China","Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Shanghai, 200135, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Reproductive Medicine, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200135, China","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I2800570007"]},{"raw_affiliation_string":"Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Shanghai, 200135, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028603894","display_name":"Yun Wei Sun","orcid":"https://orcid.org/0000-0002-9073-8142","observed_orcids":["https://orcid.org/0000-0002-9073-8142"]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I2800570007","display_name":"Renji Hospital","ror":"https://ror.org/03ypbx660","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2800570007"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yun Sun","raw_affiliation_strings":["Center for Reproductive Medicine, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200135, China","Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Shanghai, 200135, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Reproductive Medicine, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200135, China","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I2800570007"]},{"raw_affiliation_string":"Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Shanghai, 200135, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108064842","display_name":"Zi\u2010Jiang Chen","orcid":"https://orcid.org/0000-0001-6637-6631","observed_orcids":["https://orcid.org/0000-0001-6637-6631"]},"institutions":[{"id":"https://openalex.org/I154099455","display_name":"Shandong University","ror":"https://ror.org/0207yh398","country_code":"CN","type":"education","lineage":["https://openalex.org/I154099455"]},{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I2800570007","display_name":"Renji Hospital","ror":"https://ror.org/03ypbx660","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2800570007"]},{"id":"https://openalex.org/I4405277027","display_name":"Hospital for Reproductive Medicine Affiliated to Shandong University","ror":"https://ror.org/0168ksk34","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4405277027"]},{"id":"https://openalex.org/I83519826","display_name":"Nanjing Medical University","ror":"https://ror.org/059gcgy73","country_code":"CN","type":"education","lineage":["https://openalex.org/I83519826"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Zi-Jiang Chen","raw_affiliation_strings":["Center for Reproductive Medicine, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200135, China. chenzijiang@hotmail.com","Center for Reproductive Medicine, Shandong University, National Research Center for Assisted Reproductive Technology and Reproductive Genetics, Key Laboratory of Reproductive Endocrinology of Ministry of Education, Shandong Provincial Key Laboratory of Reproductive Medicine, Jinan, Shandong, 250012, China. chenzijiang@hotmail.com","NMU-SD Suzhou Collaborative Innovation Center for Reproductive Medicine, Suzhou, Jiangsu, China. chenzijiang@hotmail.com","Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Shanghai, 200135, China. chenzijiang@hotmail.com","Center for Reproductive Medicine, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200135, China"],"raw_orcid":"https://orcid.org/0000-0001-6637-6631","affiliations":[{"raw_affiliation_string":"Center for Reproductive Medicine, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200135, China. chenzijiang@hotmail.com","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I2800570007"]},{"raw_affiliation_string":"Center for Reproductive Medicine, Shandong University, National Research Center for Assisted Reproductive Technology and Reproductive Genetics, Key Laboratory of Reproductive Endocrinology of Ministry of Education, Shandong Provincial Key Laboratory of Reproductive Medicine, Jinan, Shandong, 250012, China. chenzijiang@hotmail.com","institution_ids":["https://openalex.org/I154099455","https://openalex.org/I4405277027"]},{"raw_affiliation_string":"NMU-SD Suzhou Collaborative Innovation Center for Reproductive Medicine, Suzhou, Jiangsu, China. chenzijiang@hotmail.com","institution_ids":["https://openalex.org/I83519826"]},{"raw_affiliation_string":"Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Shanghai, 200135, China. chenzijiang@hotmail.com","institution_ids":[]},{"raw_affiliation_string":"Center for Reproductive Medicine, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200135, China","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I2800570007"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5078856013","display_name":"Yanzhi Du","orcid":"https://orcid.org/0000-0002-7322-3390","observed_orcids":["https://orcid.org/0000-0002-7322-3390"]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I2800570007","display_name":"Renji Hospital","ror":"https://ror.org/03ypbx660","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2800570007"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Yanzhi Du","raw_affiliation_strings":["Center for Reproductive Medicine, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200135, China. duyz@sjtu.edu.cn","Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Shanghai, 200135, China. duyz@sjtu.edu.cn","Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Shanghai, 200135, China"],"raw_orcid":"https://orcid.org/0000-0002-7322-3390","affiliations":[{"raw_affiliation_string":"Center for Reproductive Medicine, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200135, China. duyz@sjtu.edu.cn","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I2800570007"]},{"raw_affiliation_string":"Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Shanghai, 200135, China. duyz@sjtu.edu.cn","institution_ids":["https://openalex.org/I183067930"]},{"raw_affiliation_string":"Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Shanghai, 200135, China","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5078856013","https://openalex.org/A5108064842"],"corresponding_institution_ids":["https://openalex.org/I154099455","https://openalex.org/I183067930","https://openalex.org/I2800570007","https://openalex.org/I4405277027","https://openalex.org/I83519826"],"apc_list":{"value":3690,"currency":"USD","value_usd":3690},"apc_paid":{"value":3690,"currency":"USD","value_usd":3690},"fwci":7.1889,"has_fulltext":true,"cited_by_count":30,"citation_normalized_percentile":{"value":0.9805979,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":93,"max":100},"biblio":{"volume":"9","issue":"1","first_page":"47","last_page":"47"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10390","display_name":"Ovarian function and disorders","score":0.8740000128746033,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10390","display_name":"Ovarian function and disorders","score":0.8740000128746033,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.08829999715089798,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10141","display_name":"Probiotics and Fermented Foods","score":0.012299999594688416,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/limosilactobacillus-reuteri","display_name":"Lactobacillus reuteri","score":0.9589999914169312},{"id":"https://openalex.org/keywords/polycystic-ovary-syndrome","display_name":"polycystic ovary syndrome","score":0.9990000128746033},{"id":"https://openalex.org/keywords/dyslipidemia","display_name":"dyslipidemia","score":0.8690000176429749},{"id":"https://openalex.org/keywords/decanoic-acid","display_name":"capric acid","score":0.9300000071525574},{"id":"https://openalex.org/keywords/galr1","display_name":"galanin receptor 1","score":0.7620000243186951},{"id":"https://openalex.org/keywords/rev-erbalpha","display_name":"NR1D1","score":0.8600000143051147},{"id":"https://openalex.org/keywords/srebp-1","display_name":"SREBP1","score":0.9990000128746033},{"id":"https://openalex.org/keywords/pi3k-akt-signaling","display_name":"PI3K/Akt signaling","score":0.8140000104904175},{"id":"https://openalex.org/keywords/hepatic-lipid-metabolism","display_name":"hepatic lipid metabolism","score":0.949999988079071},{"id":"https://openalex.org/keywords/gut-microbiota","display_name":"gut microbiota","score":0.7760000228881836},{"id":"https://openalex.org/keywords/darkness-exposure","display_name":"darkness exposure","score":0.6629999876022339},{"id":"https://openalex.org/keywords/clostridium-sensu-stricto-1","display_name":"Clostridium sensu stricto 1","score":0.9570000171661377}],"concepts":[{"id":"https://openalex.org/C3018442814","wikidata":"https://www.wikidata.org/wiki/Q500816","display_name":"Polycystic ovary","level":4,"score":0.672130823135376},{"id":"https://openalex.org/C2775898472","wikidata":"https://www.wikidata.org/wiki/Q597078","display_name":"Lactobacillus reuteri","level":4,"score":0.6316573023796082},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5840306878089905},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5685898661613464},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5394282341003418},{"id":"https://openalex.org/C39321552","wikidata":"https://www.wikidata.org/wiki/Q18052005","display_name":"G protein-coupled bile acid receptor","level":3,"score":0.4538092613220215},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.42853909730911255},{"id":"https://openalex.org/C2779399885","wikidata":"https://www.wikidata.org/wiki/Q413288","display_name":"Bile acid","level":2,"score":0.3323034346103668},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.219998300075531},{"id":"https://openalex.org/C2777391703","wikidata":"https://www.wikidata.org/wiki/Q1053470","display_name":"Insulin resistance","level":3,"score":0.2011559009552002},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.174818217754364},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.08294275403022766},{"id":"https://openalex.org/C100544194","wikidata":"https://www.wikidata.org/wiki/Q41760","display_name":"Fermentation","level":2,"score":0.0},{"id":"https://openalex.org/C2780206646","wikidata":"https://www.wikidata.org/wiki/Q1061596","display_name":"Lactobacillus","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003652","descriptor_name":"Decanoic Acids","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011085","descriptor_name":"Polycystic Ovary Syndrome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019869","descriptor_name":"Phosphatidylinositol 3-Kinases","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D044091","descriptor_name":"Receptor, Galanin, Type 1","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D050171","descriptor_name":"Dyslipidemias","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D050171","descriptor_name":"Dyslipidemias","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D052200","descriptor_name":"Limosilactobacillus reuteri","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1038/s41522-023-00415-2","doi":"https://doi.org/10.1038/s41522-023-00415-2","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41522-023-00415-2","pdf_url":"https://www.nature.com/articles/s41522-023-00415-2.pdf","source":{"id":"https://openalex.org/S4210229179","display_name":"npj Biofilms and Microbiomes","issn_l":"2055-5008","issn":["2055-5008"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"npj Biofilms and Microbiomes","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:10329655","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10329655","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10329655/pdf/41522_2023_Article_415.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"NPJ Biofilms Microbiomes","raw_type":"Text"},{"id":"pmid:37422471","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37422471","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"NPJ biofilms and microbiomes","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:3a0ec04d0532463ab4a68fe065b41ac4","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/3a0ec04d0532463ab4a68fe065b41ac4","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"npj Biofilms and Microbiomes, Vol 9, Iss 1, Pp 1-18 (2023)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1038/s41522-023-00415-2","doi":"https://doi.org/10.1038/s41522-023-00415-2","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41522-023-00415-2","pdf_url":"https://www.nature.com/articles/s41522-023-00415-2.pdf","source":{"id":"https://openalex.org/S4210229179","display_name":"npj Biofilms and Microbiomes","issn_l":"2055-5008","issn":["2055-5008"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"npj Biofilms and Microbiomes","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9940000176429749,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2290449032","display_name":null,"funder_award_id":"82171623","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G4572439582","display_name":null,"funder_award_id":"20DZ2270900","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G4824774712","display_name":"Functional Electrical Stimulation and Volitional Effort Training","funder_award_id":"R21HD085527","funder_id":"https://openalex.org/F4320337611","funder_display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development"},{"id":"https://openalex.org/G7655072741","display_name":null,"funder_award_id":"2021YFC2701104","funder_id":"https://openalex.org/F4320335777","funder_display_name":"National Key Research and Development Program of China"},{"id":"https://openalex.org/G7937518344","display_name":null,"funder_award_id":"20DZ2270900","funder_id":"https://openalex.org/F4320335777","funder_display_name":"National Key Research and Development Program of China"},{"id":"https://openalex.org/G8447029570","display_name":null,"funder_award_id":"81971343","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G8954423926","display_name":null,"funder_award_id":"2022YFC2703204","funder_id":"https://openalex.org/F4320335777","funder_display_name":"National Key Research and Development Program of China"}],"funders":[{"id":"https://openalex.org/F1831464670","display_name":"Innovative Research Team of High-level Local University in Shanghai","ror":null},{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320321543","display_name":"China Postdoctoral Science Foundation","ror":"https://ror.org/0426zh255"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320335777","display_name":"National Key Research and Development Program of China","ror":null},{"id":"https://openalex.org/F4320335796","display_name":"Program of Shanghai Academic Research Leader","ror":null},{"id":"https://openalex.org/F4320337611","display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","ror":"https://ror.org/04byxyr05"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4383620182.pdf","grobid_xml":"https://content.openalex.org/works/W4383620182.grobid-xml"},"referenced_works_count":63,"referenced_works":["https://openalex.org/W1577097214","https://openalex.org/W1817593152","https://openalex.org/W1979657192","https://openalex.org/W1992714654","https://openalex.org/W2038531680","https://openalex.org/W2065256407","https://openalex.org/W2095098889","https://openalex.org/W2113329249","https://openalex.org/W2115583552","https://openalex.org/W2124509857","https://openalex.org/W2125872854","https://openalex.org/W2128073839","https://openalex.org/W2133474627","https://openalex.org/W2136879851","https://openalex.org/W2159189181","https://openalex.org/W2289753669","https://openalex.org/W2339818293","https://openalex.org/W2428595929","https://openalex.org/W2491792625","https://openalex.org/W2519479884","https://openalex.org/W2763111141","https://openalex.org/W2764270648","https://openalex.org/W2774052104","https://openalex.org/W2801740840","https://openalex.org/W2802808126","https://openalex.org/W2807299193","https://openalex.org/W2883879320","https://openalex.org/W2895180682","https://openalex.org/W2904554634","https://openalex.org/W2910307871","https://openalex.org/W2925187227","https://openalex.org/W2943746255","https://openalex.org/W2948631669","https://openalex.org/W2961936017","https://openalex.org/W2963985015","https://openalex.org/W2974432944","https://openalex.org/W2982293051","https://openalex.org/W2999591185","https://openalex.org/W3000107600","https://openalex.org/W3005100840","https://openalex.org/W3006437411","https://openalex.org/W3010639002","https://openalex.org/W3021424776","https://openalex.org/W3088203083","https://openalex.org/W3094209736","https://openalex.org/W3094508051","https://openalex.org/W3095661830","https://openalex.org/W3096697675","https://openalex.org/W3099324828","https://openalex.org/W3104417093","https://openalex.org/W3109131936","https://openalex.org/W3110600404","https://openalex.org/W3117500392","https://openalex.org/W3126193027","https://openalex.org/W3127197816","https://openalex.org/W3128410459","https://openalex.org/W3158695921","https://openalex.org/W3163849157","https://openalex.org/W3165173988","https://openalex.org/W3193700421","https://openalex.org/W4220686162","https://openalex.org/W4221084275","https://openalex.org/W4283575264"],"related_works":["https://openalex.org/W3002034488","https://openalex.org/W6921187208","https://openalex.org/W4416937163","https://openalex.org/W3006437411","https://openalex.org/W4307274159","https://openalex.org/W2936949822","https://openalex.org/W2339818293","https://openalex.org/W4383533057","https://openalex.org/W4414923295","https://openalex.org/W7155064440"],"abstract_inverted_index":{"Knowledge":[0],"gaps":[1],"that":[2,17,75,219],"limit":[3],"the":[4,34,93,124,150,175,200],"development":[5],"of":[6,29,36,45,54,152,196,203,229],"therapies":[7],"for":[8,224,236],"polycystic":[9],"ovary":[10],"syndrome":[11],"(PCOS)":[12],"concern":[13],"various":[14],"environmental":[15],"factors":[16],"impact":[18],"clinical":[19,237],"characteristics.":[20],"Circadian":[21],"dysrhythmia":[22],"contributes":[23],"to":[24,62,83,100,138,189,240],"glycometabolic":[25],"and":[26,111,157],"reproductive":[27],"hallmarks":[28],"PCOS.":[30,66],"Here,":[31],"we":[32],"illustrated":[33],"amelioration":[35],"Limosilactobacillus":[37],"reuteri":[38,136,146,188,205,221],"(L.":[39],"reuteri)":[40],"on":[41],"biorhythm":[42,242],"disorder-ignited":[43,243],"dyslipidemia":[44,244],"PCOS":[46,209,246],"via":[47],"a":[48,88,130],"microbiota-metabolite-liver":[49],"axis.":[50],"A":[51],"rat":[52],"model":[53],"long-term":[55],"(8":[56],"weeks)":[57],"darkness":[58,84,140],"treatment":[59,195],"was":[60],"used":[61],"mimic":[63],"circadian":[64,207,225],"dysrhythmia-induced":[65],"Hepatic":[67],"transcriptomics":[68],"certified":[69],"by":[70],"in":[71,92,123,149,174,206,245],"vitro":[72],"experiments":[73],"demonstrated":[74],"increased":[76],"hepatic":[77,213],"galanin":[78],"receptor":[79],"1":[80,109,118,156],"(GALR1)":[81],"due":[82],"exposure":[85],"functioned":[86],"as":[87,160,162,186],"critical":[89],"upstream":[90],"factor":[91],"phosphoinositide":[94],"3-kinase":[95],"(PI3K)/protein":[96],"kinase":[97],"B":[98],"pathway":[99,173],"suppress":[101],"nuclear":[102],"receptors":[103],"subfamily":[104],"1,":[105],"group":[106],"D,":[107],"member":[108],"(NR1D1)":[110],"promoted":[112],"sterol":[113],"regulatory":[114],"element":[115],"binding":[116],"protein":[117],"(SREBP1),":[119],"inducing":[120],"lipid":[121,214],"accumulation":[122],"liver.":[125,176],"Further":[126],"investigations":[127],"figured":[128],"out":[129],"restructured":[131],"microbiome-metabolome":[132],"network":[133],"following":[134],"L.":[135,145,187,204,220,230],"administration":[137],"protect":[139,190],"rats":[141],"against":[142,191],"dyslipidemia.":[143,192,227],"Notably,":[144],"intervention":[147],"resulted":[148],"decrease":[151],"Clostridium":[153],"sensu":[154],"stricto":[155],"Ruminococcaceae":[158],"UCG-010":[159],"well":[161],"gut":[163],"microbiota-derived":[164],"metabolite":[165],"capric":[166,197],"acid,":[167],"which":[168],"could":[169,222],"further":[170],"inhibit":[171],"GALR1-NR1D1-SREBP1":[172],"In":[177],"addition,":[178],"GALR":[179],"antagonist":[180],"M40":[181],"reproduced":[182],"similar":[183],"ameliorative":[184],"effects":[185,202],"While":[193],"exogenous":[194],"acid":[198],"restrained":[199],"protective":[201],"disruption-induced":[208],"through":[210],"inhibiting":[211],"GALR1-dependent":[212],"metabolism.":[215],"These":[216],"findings":[217],"purport":[218],"serve":[223],"disruption-associated":[226],"Manipulation":[228],"reuteri-capric":[231],"acid-GALR1":[232],"axis":[233],"paves":[234],"way":[235],"therapeutic":[238],"strategies":[239],"prevent":[241],"women.":[247]},"counts_by_year":[{"year":2026,"cited_by_count":10},{"year":2025,"cited_by_count":12},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2023-07-09T00:00:00"}
