{"id":"https://openalex.org/W4383558877","doi":"https://doi.org/10.1016/j.bios.2023.115506","title":"Microneedle coupled epidermal sensor for multiplexed electrochemical detection of kidney disease biomarkers","display_name":"Microneedle coupled epidermal sensor for multiplexed electrochemical detection of kidney disease biomarkers","publication_year":2023,"publication_date":"2023-07-07","ids":{"openalex":"https://openalex.org/W4383558877","doi":"https://doi.org/10.1016/j.bios.2023.115506","pmid":"https://pubmed.ncbi.nlm.nih.gov/37473548"},"language":"en","primary_location":{"id":"doi:10.1016/j.bios.2023.115506","doi":"https://doi.org/10.1016/j.bios.2023.115506","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.bios.2023.115506","pdf_url":null,"source":{"id":"https://openalex.org/S156181945","display_name":"Biosensors and Bioelectronics","issn_l":"0956-5663","issn":["0956-5663","1873-4235"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","jufo-3","medline","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biosensors and Bioelectronics","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5025510038","display_name":"Lewen Zheng","orcid":"https://orcid.org/0000-0002-0685-3253","observed_orcids":["https://orcid.org/0000-0002-0685-3253"]},"institutions":[{"id":"https://openalex.org/I172675005","display_name":"Nanyang Technological University","ror":"https://ror.org/02e7b5302","country_code":"SG","type":"education","lineage":["https://openalex.org/I172675005"]}],"countries":["SG"],"is_corresponding":true,"raw_author_name":"Lewen Zheng","raw_affiliation_strings":["School of Chemistry, Chemical Engineering and Biotechnology, Nanyang Technological University, 637457, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Chemistry, Chemical Engineering and Biotechnology, Nanyang Technological University, 637457, Singapore","institution_ids":["https://openalex.org/I172675005"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100559650","display_name":"Dandan Zhu","orcid":"https://orcid.org/0009-0005-8830-7481","observed_orcids":["https://orcid.org/0009-0005-8830-7481"]},"institutions":[{"id":"https://openalex.org/I172675005","display_name":"Nanyang Technological University","ror":"https://ror.org/02e7b5302","country_code":"SG","type":"education","lineage":["https://openalex.org/I172675005"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Dandan Zhu","raw_affiliation_strings":["School of Chemistry, Chemical Engineering and Biotechnology, Nanyang Technological University, 637457, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Chemistry, Chemical Engineering and Biotechnology, Nanyang Technological University, 637457, Singapore","institution_ids":["https://openalex.org/I172675005"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101787310","display_name":"Yi Xiao","orcid":"https://orcid.org/0000-0002-1389-3106","observed_orcids":["https://orcid.org/0000-0002-1389-3106"]},"institutions":[{"id":"https://openalex.org/I172675005","display_name":"Nanyang Technological University","ror":"https://ror.org/02e7b5302","country_code":"SG","type":"education","lineage":["https://openalex.org/I172675005"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Yi Xiao","raw_affiliation_strings":["School of Chemistry, Chemical Engineering and Biotechnology, Nanyang Technological University, 637457, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Chemistry, Chemical Engineering and Biotechnology, Nanyang Technological University, 637457, Singapore","institution_ids":["https://openalex.org/I172675005"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Xinting Zheng","orcid":"https://orcid.org/0000-0002-1431-0929","observed_orcids":["https://orcid.org/0000-0002-1431-0929"]},"institutions":[{"id":"https://openalex.org/I115228651","display_name":"Agency for Science, Technology and Research","ror":"https://ror.org/036wvzt09","country_code":"SG","type":"government","lineage":["https://openalex.org/I115228651"]},{"id":"https://openalex.org/I4210123095","display_name":"Institute of Materials Research and Engineering","ror":"https://ror.org/02sepg748","country_code":"SG","type":"facility","lineage":["https://openalex.org/I115228651","https://openalex.org/I4210123095","https://openalex.org/I91275662"]}],"countries":["SG"],"is_corresponding":true,"raw_author_name":"Xinting Zheng","raw_affiliation_strings":["Institute of Materials Research and Engineering (IMRE), Agency for Science, Technology and Research (A*STAR), 2 Fusionopolis Way, Innovis #08-03, 138634, Singapore. Electronic address: zhengxt@imre.a-star.edu.sg","Institute of Materials Research and Engineering (IMRE), Agency for Science, Technology and Research (A*STAR), 2 Fusionopolis Way, Innovis #08-03, 138634, Singapore"],"raw_orcid":"https://orcid.org/0000-0002-1431-0929","affiliations":[{"raw_affiliation_string":"Institute of Materials Research and Engineering (IMRE), Agency for Science, Technology and Research (A*STAR), 2 Fusionopolis Way, Innovis #08-03, 138634, Singapore. Electronic address: zhengxt@imre.a-star.edu.sg","institution_ids":["https://openalex.org/I115228651","https://openalex.org/I4210123095"]},{"raw_affiliation_string":"Institute of Materials Research and Engineering (IMRE), Agency for Science, Technology and Research (A*STAR), 2 Fusionopolis Way, Innovis #08-03, 138634, Singapore","institution_ids":["https://openalex.org/I115228651","https://openalex.org/I4210123095"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5037511088","display_name":"Peng Chen","orcid":"https://orcid.org/0000-0003-3730-1846","observed_orcids":["https://orcid.org/0000-0003-3730-1846","https://orcid.org/0000-0002-8210-8562"]},"institutions":[{"id":"https://openalex.org/I172675005","display_name":"Nanyang Technological University","ror":"https://ror.org/02e7b5302","country_code":"SG","type":"education","lineage":["https://openalex.org/I172675005"]},{"id":"https://openalex.org/I4405254580","display_name":"Skin Research Institute of Singapore","ror":"https://ror.org/01ztxwq91","country_code":"SG","type":"government","lineage":["https://openalex.org/I4405254580"]},{"id":"https://openalex.org/I4405276784","display_name":"Institute for Digital Molecular Analytics and Science","ror":"https://ror.org/009xtw325","country_code":"SG","type":"facility","lineage":["https://openalex.org/I4405276784"]}],"countries":["SG"],"is_corresponding":true,"raw_author_name":"Peng Chen","raw_affiliation_strings":["School of Chemistry, Chemical Engineering and Biotechnology, Nanyang Technological University, 637457, Singapore; Skin Research Institute of Singapore, 308232, Singapore; Lee Kong Chian School of Medicine, Institute for Digital Molecular Analytics and Science, Nanyang Technological University, 636921, Singapore. Electronic address: chenpeng@ntu.edu.sg","Lee Kong Chian School of Medicine, Institute for Digital Molecular Analytics and Science, Nanyang Technological University, 636921, Singapore","School of Chemistry, Chemical Engineering and Biotechnology, Nanyang Technological University, 637457, Singapore","Skin Research Institute of Singapore, 308232, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Chemistry, Chemical Engineering and Biotechnology, Nanyang Technological University, 637457, Singapore; Skin Research Institute of Singapore, 308232, Singapore; Lee Kong Chian School of Medicine, Institute for Digital Molecular Analytics and Science, Nanyang Technological University, 636921, Singapore. Electronic address: chenpeng@ntu.edu.sg","institution_ids":["https://openalex.org/I172675005","https://openalex.org/I4405254580","https://openalex.org/I4405276784"]},{"raw_affiliation_string":"Lee Kong Chian School of Medicine, Institute for Digital Molecular Analytics and Science, Nanyang Technological University, 636921, Singapore","institution_ids":["https://openalex.org/I172675005","https://openalex.org/I4405276784"]},{"raw_affiliation_string":"School of Chemistry, Chemical Engineering and Biotechnology, Nanyang Technological University, 637457, Singapore","institution_ids":["https://openalex.org/I172675005"]},{"raw_affiliation_string":"Skin Research Institute of Singapore, 308232, Singapore","institution_ids":["https://openalex.org/I4405254580"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5025510038","https://openalex.org/A5037511088"],"corresponding_institution_ids":["https://openalex.org/I115228651","https://openalex.org/I172675005","https://openalex.org/I4210123095","https://openalex.org/I4405254580","https://openalex.org/I4405276784"],"apc_list":{"value":5090,"currency":"USD","value_usd":5090},"apc_paid":null,"fwci":7.1608,"has_fulltext":false,"cited_by_count":75,"citation_normalized_percentile":{"value":0.99168371,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":100},"biblio":{"volume":"237","issue":null,"first_page":"115506","last_page":"115506"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10212","display_name":"Electrochemical sensors and biosensors","score":0.9545999765396118,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10212","display_name":"Electrochemical sensors and biosensors","score":0.9545999765396118,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10704","display_name":"Advancements in Transdermal Drug Delivery","score":0.011900000274181366,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10338","display_name":"Advanced Sensor and Energy Harvesting Materials","score":0.006500000134110451,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/microneedles","display_name":"microneedles","score":0.8579999804496765},{"id":"https://openalex.org/keywords/electrochemical-sensor-array","display_name":"electrochemical sensor array","score":0.847000002861023},{"id":"https://openalex.org/keywords/chronic-kidney-disease","display_name":"chronic kidney disease","score":0.7279999852180481},{"id":"https://openalex.org/keywords/kidney-disease-biomarkers","display_name":"kidney disease biomarkers","score":0.878000020980835},{"id":"https://openalex.org/keywords/interstitial-fluid","display_name":"interstitial fluid","score":0.9459999799728394},{"id":"https://openalex.org/keywords/phosphate","display_name":"phosphate","score":0.6759999990463257},{"id":"https://openalex.org/keywords/uric-acid","display_name":"uric acid","score":0.996999979019165},{"id":"https://openalex.org/keywords/creatinine","display_name":"creatinine","score":1.0},{"id":"https://openalex.org/keywords/urea","display_name":"urea","score":1.0},{"id":"https://openalex.org/keywords/artificial-skin-model","display_name":"artificial skin model","score":0.7860000133514404},{"id":"https://openalex.org/keywords/multiplexed-detection","display_name":"multiplexed detection","score":0.7409999966621399}],"concepts":[{"id":"https://openalex.org/C2778653478","wikidata":"https://www.wikidata.org/wiki/Q1054718","display_name":"Kidney disease","level":2,"score":0.6289145350456238},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.5527363419532776},{"id":"https://openalex.org/C2779881121","wikidata":"https://www.wikidata.org/wiki/Q105522","display_name":"Uric acid","level":2,"score":0.5233932137489319},{"id":"https://openalex.org/C2780091579","wikidata":"https://www.wikidata.org/wiki/Q9377","display_name":"Kidney","level":2,"score":0.47726529836654663},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.45749884843826294},{"id":"https://openalex.org/C2780306776","wikidata":"https://www.wikidata.org/wiki/Q426660","display_name":"Creatinine","level":2,"score":0.4556276500225067},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.355491042137146},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3501741886138916},{"id":"https://openalex.org/C126894567","wikidata":"https://www.wikidata.org/wiki/Q105650","display_name":"Urology","level":1,"score":0.3499218225479126},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.3452298641204834},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.306753933429718}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003404","descriptor_name":"Creatinine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004817","descriptor_name":"Epidermis","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D004867","descriptor_name":"Equipment Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009339","descriptor_name":"Needles","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014508","descriptor_name":"Urea","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014527","descriptor_name":"Uric Acid","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D014527","descriptor_name":"Uric Acid","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D015374","descriptor_name":"Biosensing Techniques","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":true},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D045604","descriptor_name":"Extracellular Fluid","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051436","descriptor_name":"Renal Insufficiency, Chronic","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D055664","descriptor_name":"Electrochemical Techniques","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1016/j.bios.2023.115506","doi":"https://doi.org/10.1016/j.bios.2023.115506","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.bios.2023.115506","pdf_url":null,"source":{"id":"https://openalex.org/S156181945","display_name":"Biosensors and Bioelectronics","issn_l":"0956-5663","issn":["0956-5663","1873-4235"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","jufo-3","medline","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biosensors and Bioelectronics","raw_type":"journal-article"},{"id":"pmid:37473548","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37473548","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biosensors & bioelectronics","raw_type":"Journal Article"},{"id":"pmh:oai:dr.ntu.edu.sg:10356/170241","doi":null,"is_oa":false,"landing_page_url":"https://hdl.handle.net/10356/170241","pdf_url":null,"source":{"id":"https://openalex.org/S4306402609","display_name":"DR-NTU (Nanyang Technological University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I172675005","host_organization_name":"Nanyang Technological University","host_organization_lineage":["https://openalex.org/I172675005"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9476000070571899,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":46,"referenced_works":["https://openalex.org/W99363107","https://openalex.org/W1511302815","https://openalex.org/W1937444536","https://openalex.org/W1983078009","https://openalex.org/W1988851807","https://openalex.org/W2005005197","https://openalex.org/W2027710937","https://openalex.org/W2032576629","https://openalex.org/W2037847893","https://openalex.org/W2054162828","https://openalex.org/W2064615698","https://openalex.org/W2075989661","https://openalex.org/W2098458611","https://openalex.org/W2116717349","https://openalex.org/W2139614876","https://openalex.org/W2140211254","https://openalex.org/W2162900617","https://openalex.org/W2164249826","https://openalex.org/W2171699178","https://openalex.org/W2515414172","https://openalex.org/W2734891260","https://openalex.org/W2753117113","https://openalex.org/W2764296511","https://openalex.org/W2786294615","https://openalex.org/W2823899845","https://openalex.org/W2885161568","https://openalex.org/W2896384067","https://openalex.org/W2903635237","https://openalex.org/W2921350205","https://openalex.org/W2949627837","https://openalex.org/W2954142086","https://openalex.org/W2964492478","https://openalex.org/W2968188421","https://openalex.org/W3001424928","https://openalex.org/W3087514203","https://openalex.org/W3107908824","https://openalex.org/W3159688892","https://openalex.org/W3198846821","https://openalex.org/W3208104288","https://openalex.org/W4206255511","https://openalex.org/W4213253511","https://openalex.org/W4221042169","https://openalex.org/W4281286285","https://openalex.org/W4282964533","https://openalex.org/W4292834101","https://openalex.org/W4311808686"],"related_works":["https://openalex.org/W7213457173","https://openalex.org/W4416731148","https://openalex.org/W4409717343","https://openalex.org/W2788766246","https://openalex.org/W4415430438","https://openalex.org/W7162296579","https://openalex.org/W4324129595","https://openalex.org/W4200074687","https://openalex.org/W4402404465","https://openalex.org/W4409787538"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":26},{"year":2025,"cited_by_count":28},{"year":2024,"cited_by_count":20},{"year":2023,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2023-07-08T00:00:00"}