{"id":"https://openalex.org/W4383422044","doi":"https://doi.org/10.1016/s0016-5085(23)01743-2","title":"Sa1210 IFN-GAMMA INCREASES THE EXPRESSION OF CLAUDIN-2 THROUGH WNT/B-CATENIN DEPENDENT SIRT2 REPRESSION","display_name":"Sa1210 IFN-GAMMA INCREASES THE EXPRESSION OF CLAUDIN-2 THROUGH WNT/B-CATENIN DEPENDENT SIRT2 REPRESSION","publication_year":2023,"publication_date":"2023-05-01","ids":{"openalex":"https://openalex.org/W4383422044","doi":"https://doi.org/10.1016/s0016-5085(23)01743-2"},"language":"en","primary_location":{"id":"doi:10.1016/s0016-5085(23)01743-2","doi":"https://doi.org/10.1016/s0016-5085(23)01743-2","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0016-5085(23)01743-2","pdf_url":"http://www.gastrojournal.org/article/S0016508523017432/pdf","source":{"id":"https://openalex.org/S143352558","display_name":"Gastroenterology","issn_l":"0016-5085","issn":["0016-5085","1528-0012"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gastroenterology","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"http://www.gastrojournal.org/article/S0016508523017432/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100429511","display_name":"Chang Li","orcid":"https://orcid.org/0000-0001-8019-3794","observed_orcids":["https://orcid.org/0000-0001-8019-3794"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Chang Li","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100701640","display_name":"Yuning Zhou","orcid":"https://orcid.org/0000-0001-8173-1718","observed_orcids":["https://orcid.org/0000-0001-8173-1718"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yuning Zhou","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023436882","display_name":"Heidi L. Weiss","orcid":"https://orcid.org/0009-0002-0980-7778","observed_orcids":["https://orcid.org/0009-0002-0980-7778"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Heidi L. Weiss","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020109340","display_name":"Qingding Wang","orcid":"https://orcid.org/0000-0001-5566-7054","observed_orcids":["https://orcid.org/0000-0001-5566-7054","https://orcid.org/0009-0002-4797-4876"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Qingding Wang","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5066347342","display_name":"Bernard Mark Evers","orcid":"https://orcid.org/0000-0002-9425-2342","observed_orcids":["https://orcid.org/0000-0002-9425-2342"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"B. Mark Evers","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3800,"currency":"USD","value_usd":3800},"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"164","issue":"6","first_page":"S","last_page":"327"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11872","display_name":"Barrier Structure and Function Studies","score":0.4027999937534332,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11872","display_name":"Barrier Structure and Function Studies","score":0.4027999937534332,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10929","display_name":"Wnt/\u03b2-catenin signaling in development and cancer","score":0.14970000088214874,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11051","display_name":"Sirtuins and Resveratrol in Medicine","score":0.09520000219345093,"subfield":{"id":"https://openalex.org/subfields/2717","display_name":"Geriatrics and Gerontology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/interferon-gamma","display_name":"interferon-gamma","score":0.972000002861023},{"id":"https://openalex.org/keywords/claudin-2","display_name":"claudin-2","score":0.9940000176429749},{"id":"https://openalex.org/keywords/wnt-beta-catenin-signaling","display_name":"Wnt/\u03b2-catenin signaling","score":0.953000009059906},{"id":"https://openalex.org/keywords/sirt2","display_name":"SIRT2","score":0.9580000042915344},{"id":"https://openalex.org/keywords/gene-expression-regulation","display_name":"gene expression regulation","score":0.6320000290870667},{"id":"https://openalex.org/keywords/intestinal-permeability","display_name":"intestinal permeability","score":0.5509999990463257},{"id":"https://openalex.org/keywords/tight-junctions","display_name":"tight junctions","score":0.7509999871253967}],"concepts":[{"id":"https://openalex.org/C186310378","wikidata":"https://www.wikidata.org/wiki/Q941796","display_name":"Psychological repression","level":4,"score":0.7795939445495605},{"id":"https://openalex.org/C51872919","wikidata":"https://www.wikidata.org/wiki/Q420863","display_name":"Claudin","level":3,"score":0.6229085922241211},{"id":"https://openalex.org/C199848840","wikidata":"https://www.wikidata.org/wiki/Q18036605","display_name":"SIRT2","level":5,"score":0.6130761504173279},{"id":"https://openalex.org/C30145163","wikidata":"https://www.wikidata.org/wiki/Q384104","display_name":"Catenin","level":4,"score":0.5978518724441528},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.486301988363266},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.47959792613983154},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.3484794795513153},{"id":"https://openalex.org/C137620995","wikidata":"https://www.wikidata.org/wiki/Q155769","display_name":"Wnt signaling pathway","level":3,"score":0.3448488414287567},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2683500647544861},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.18175950646400452},{"id":"https://openalex.org/C2780561631","wikidata":"https://www.wikidata.org/wiki/Q421331","display_name":"Sirtuin","level":4,"score":0.14028653502464294},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.10864213109016418},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.09377682209014893},{"id":"https://openalex.org/C177779419","wikidata":"https://www.wikidata.org/wiki/Q1053832","display_name":"Tight junction","level":2,"score":0.08876669406890869},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.057136327028274536},{"id":"https://openalex.org/C119157956","wikidata":"https://www.wikidata.org/wiki/Q796604","display_name":"Acetylation","level":3,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/s0016-5085(23)01743-2","doi":"https://doi.org/10.1016/s0016-5085(23)01743-2","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0016-5085(23)01743-2","pdf_url":"http://www.gastrojournal.org/article/S0016508523017432/pdf","source":{"id":"https://openalex.org/S143352558","display_name":"Gastroenterology","issn_l":"0016-5085","issn":["0016-5085","1528-0012"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gastroenterology","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1016/s0016-5085(23)01743-2","doi":"https://doi.org/10.1016/s0016-5085(23)01743-2","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0016-5085(23)01743-2","pdf_url":"http://www.gastrojournal.org/article/S0016508523017432/pdf","source":{"id":"https://openalex.org/S143352558","display_name":"Gastroenterology","issn_l":"0016-5085","issn":["0016-5085","1528-0012"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gastroenterology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8048999905586243}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4383422044.pdf","grobid_xml":"https://content.openalex.org/works/W4383422044.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4383340711","https://openalex.org/W2944084760","https://openalex.org/W2006748881","https://openalex.org/W4283020100","https://openalex.org/W2323018114","https://openalex.org/W4383379467","https://openalex.org/W7056989614","https://openalex.org/W4411998519","https://openalex.org/W2109972126","https://openalex.org/W4411998856"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-11-01T11:40:01.658920","created_date":"2023-07-07T00:00:00"}