{"id":"https://openalex.org/W4383378760","doi":"https://doi.org/10.1016/s0016-5085(23)01172-1","title":"460 BACTERIA-PRODUCED HYPOXANTHINE INCREASES SEROTONIN RELEASE AND ACCELERATES WHOLE GUT TRANSIT","display_name":"460 BACTERIA-PRODUCED HYPOXANTHINE INCREASES SEROTONIN RELEASE AND ACCELERATES WHOLE GUT TRANSIT","publication_year":2023,"publication_date":"2023-05-01","ids":{"openalex":"https://openalex.org/W4383378760","doi":"https://doi.org/10.1016/s0016-5085(23)01172-1"},"language":"en","primary_location":{"id":"doi:10.1016/s0016-5085(23)01172-1","doi":"https://doi.org/10.1016/s0016-5085(23)01172-1","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0016-5085(23)01172-1","pdf_url":"http://www.gastrojournal.org/article/S0016508523011721/pdf","source":{"id":"https://openalex.org/S143352558","display_name":"Gastroenterology","issn_l":"0016-5085","issn":["0016-5085","1528-0012"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gastroenterology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"http://www.gastrojournal.org/article/S0016508523011721/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100442759","display_name":"Yang Xiao","orcid":"https://orcid.org/0000-0002-0516-0543","observed_orcids":["https://orcid.org/0000-0002-0516-0543"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yang Xiao","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067528247","display_name":"Tijs Louwies","orcid":"https://orcid.org/0000-0003-4860-6100","observed_orcids":["https://orcid.org/0000-0003-4860-6100"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Tijs Louwies","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023913877","display_name":"Arnaldo Mercado\u2010Perez","orcid":"https://orcid.org/0000-0001-8036-6771","observed_orcids":["https://orcid.org/0000-0001-8036-6771"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Arnaldo Mercado-Perez","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016435481","display_name":"Meng Pu","orcid":"https://orcid.org/0000-0001-6092-8124","observed_orcids":["https://orcid.org/0000-0001-6092-8124"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Meng Pu","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Julia Willett","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Julia Willett","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030763440","display_name":"Lisa M. Till","orcid":"https://orcid.org/0000-0003-4943-3125","observed_orcids":["https://orcid.org/0000-0003-4943-3125"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Lisa Till","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079580565","display_name":"Y. S. Prakash","orcid":"https://orcid.org/0000-0002-2968-224X","observed_orcids":["https://orcid.org/0000-0002-2968-224X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Y.S. Prakash","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012218827","display_name":"Arthur Beyder","orcid":"https://orcid.org/0000-0002-9225-4854","observed_orcids":["https://orcid.org/0000-0002-9225-4854"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Arthur Beyder","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022334133","display_name":"Kristen Smith","orcid":"https://orcid.org/0000-0002-9330-4454","observed_orcids":["https://orcid.org/0000-0002-9330-4454"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kristen Smith-Edwards","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079952114","display_name":"Gianrico Farrugia","orcid":"https://orcid.org/0000-0003-3473-5235","observed_orcids":["https://orcid.org/0000-0003-3473-5235"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Gianrico Farrugia","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5065937262","display_name":"Purna Kashyap","orcid":"https://orcid.org/0000-0002-2851-2388","observed_orcids":["https://orcid.org/0000-0002-2851-2388"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Purna Kashyap","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3800,"currency":"USD","value_usd":3800},"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.16061232,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"164","issue":"6","first_page":"S","last_page":"87"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10365","display_name":"Gastrointestinal motility and disorders","score":0.9839000105857849,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10365","display_name":"Gastrointestinal motility and disorders","score":0.9839000105857849,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.008100000210106373,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11337","display_name":"Tryptophan and brain disorders","score":0.0012000000569969416,"subfield":{"id":"https://openalex.org/subfields/2803","display_name":"Biological Psychiatry"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hypoxanthine","display_name":"hypoxanthine","score":0.859000027179718},{"id":"https://openalex.org/keywords/serotonin-release","display_name":"serotonin release","score":0.7269999980926514},{"id":"https://openalex.org/keywords/gastrointestinal-transit","display_name":"gastrointestinal transit","score":0.8149999976158142},{"id":"https://openalex.org/keywords/intestinal-motility","display_name":"intestinal motility","score":0.6859999895095825},{"id":"https://openalex.org/keywords/gut-microbiota","display_name":"gut microbiota","score":0.6570000052452087},{"id":"https://openalex.org/keywords/gut-brain-axis","display_name":"gut-brain axis","score":0.5320000052452087}],"concepts":[{"id":"https://openalex.org/C2781116151","wikidata":"https://www.wikidata.org/wiki/Q410305","display_name":"Hypoxanthine","level":3,"score":0.7777556777000427},{"id":"https://openalex.org/C2775864247","wikidata":"https://www.wikidata.org/wiki/Q167934","display_name":"Serotonin","level":3,"score":0.5578532814979553},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5158633589744568},{"id":"https://openalex.org/C2778022998","wikidata":"https://www.wikidata.org/wiki/Q651136","display_name":"Transit (satellite)","level":3,"score":0.4682871699333191},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.4656413793563843},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.27761584520339966},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2058435082435608},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.04570150375366211},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.03212624788284302},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.0},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0},{"id":"https://openalex.org/C22212356","wikidata":"https://www.wikidata.org/wiki/Q775325","display_name":"Transport engineering","level":1,"score":0.0},{"id":"https://openalex.org/C539828613","wikidata":"https://www.wikidata.org/wiki/Q178512","display_name":"Public transport","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/s0016-5085(23)01172-1","doi":"https://doi.org/10.1016/s0016-5085(23)01172-1","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0016-5085(23)01172-1","pdf_url":"http://www.gastrojournal.org/article/S0016508523011721/pdf","source":{"id":"https://openalex.org/S143352558","display_name":"Gastroenterology","issn_l":"0016-5085","issn":["0016-5085","1528-0012"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gastroenterology","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1016/s0016-5085(23)01172-1","doi":"https://doi.org/10.1016/s0016-5085(23)01172-1","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0016-5085(23)01172-1","pdf_url":"http://www.gastrojournal.org/article/S0016508523011721/pdf","source":{"id":"https://openalex.org/S143352558","display_name":"Gastroenterology","issn_l":"0016-5085","issn":["0016-5085","1528-0012"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gastroenterology","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4383378760.pdf","grobid_xml":"https://content.openalex.org/works/W4383378760.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4382011138","https://openalex.org/W3125294206","https://openalex.org/W2067264963","https://openalex.org/W7055967614","https://openalex.org/W1996884324","https://openalex.org/W7025030309","https://openalex.org/W7037235397","https://openalex.org/W2033386838","https://openalex.org/W2605661583","https://openalex.org/W1530411393"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-29T09:56:32.521200","created_date":"2023-07-07T00:00:00"}