{"id":"https://openalex.org/W4383265185","doi":"https://doi.org/10.1158/1541-7786.23627422","title":"Supplementary Table 6 from Disruption of the MYC Superenhancer Complex by Dual Targeting of FLT3 and LSD1 in Acute Myeloid Leukemia","display_name":"Supplementary Table 6 from Disruption of the MYC Superenhancer Complex by Dual Targeting of FLT3 and LSD1 in Acute Myeloid Leukemia","publication_year":2023,"publication_date":"2023-07-05","ids":{"openalex":"https://openalex.org/W4383265185","doi":"https://doi.org/10.1158/1541-7786.23627422"},"language":"en","primary_location":{"id":"doi:10.1158/1541-7786.23627422","doi":"https://doi.org/10.1158/1541-7786.23627422","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1541-7786.23627422","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"volume":null,"type":"supplementary-materials","is_traditional":false,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1158/1541-7786.23627422","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5028626481","display_name":"William M. Yashar","orcid":"https://orcid.org/0000-0002-8850-9850","observed_orcids":["https://orcid.org/0000-0002-8850-9850"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"William M. Yashar","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-8850-9850","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060581274","display_name":"Brittany M. Curtiss","orcid":"https://orcid.org/0000-0002-5274-8323","observed_orcids":["https://orcid.org/0000-0002-5274-8323"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Brittany M. Curtiss","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-5274-8323","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068010590","display_name":"Daniel J. Coleman","orcid":"https://orcid.org/0000-0002-3414-3160","observed_orcids":["https://orcid.org/0000-0002-3414-3160"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Daniel J. Coleman","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-3414-3160","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032148008","display_name":"Jake VanCampen","orcid":"https://orcid.org/0000-0003-1361-0927","observed_orcids":["https://orcid.org/0000-0003-1361-0927"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jake VanCampen","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-1361-0927","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025186197","display_name":"Garth Kong","orcid":"https://orcid.org/0000-0001-5262-5406","observed_orcids":["https://orcid.org/0000-0001-5262-5406"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Garth Kong","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-5262-5406","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029691160","display_name":"Jommel Macaraeg","orcid":"https://orcid.org/0000-0002-6307-5056","observed_orcids":["https://orcid.org/0000-0002-6307-5056"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jommel Macaraeg","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-6307-5056","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069454150","display_name":"Joseph Estabrook","orcid":"https://orcid.org/0000-0002-1027-3315","observed_orcids":["https://orcid.org/0000-0002-1027-3315"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Joseph Estabrook","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-1027-3315","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037803004","display_name":"Emek Demir","orcid":"https://orcid.org/0000-0002-3663-7113","observed_orcids":["https://orcid.org/0000-0002-3663-7113"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Emek Demir","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-3663-7113","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046733014","display_name":"Nicola Long","orcid":"https://orcid.org/0000-0002-9010-8167","observed_orcids":["https://orcid.org/0000-0002-9010-8167"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Nicola Long","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-9010-8167","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061516412","display_name":"Daniel Bottomly","orcid":"https://orcid.org/0000-0001-7191-0990","observed_orcids":["https://orcid.org/0000-0001-7191-0990"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Daniel Bottomly","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-7191-0990","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066373576","display_name":"Shannon K. McWeeney","orcid":"https://orcid.org/0000-0001-8333-6607","observed_orcids":["https://orcid.org/0000-0001-8333-6607"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Shannon K. McWeeney","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-8333-6607","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5134831711","display_name":"Jeffrey W Tyner","orcid":"https://orcid.org/0000-0002-2133-0960","observed_orcids":["https://orcid.org/0000-0002-2133-0960"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jeffrey W. Tyner","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-2133-0960","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5125591963","display_name":"Brian J. Druker","orcid":"https://orcid.org/0000-0001-8331-8206","observed_orcids":["https://orcid.org/0000-0001-8331-8206"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Brian J. Druker","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-8331-8206","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073522080","display_name":"Julia E. Maxson","orcid":"https://orcid.org/0000-0002-3871-7221","observed_orcids":["https://orcid.org/0000-0002-3871-7221"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Julia E. Maxson","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-3871-7221","affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5032381895","display_name":"Theodore P. Braun","orcid":"https://orcid.org/0000-0002-6248-2143","observed_orcids":["https://orcid.org/0000-0002-6248-2143"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Theodore P. Braun","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-6248-2143","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10309","display_name":"Acute Myeloid Leukemia Research","score":0.9833999872207642,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10309","display_name":"Acute Myeloid Leukemia Research","score":0.9833999872207642,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12820","display_name":"Chromatin Remodeling and Cancer","score":0.005400000140070915,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.003100000089034438,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/myc-super-enhancer","display_name":"MYC superenhancer","score":0.8389999866485596},{"id":"https://openalex.org/keywords/flt3","display_name":"FLT3","score":0.6990000009536743},{"id":"https://openalex.org/keywords/lsd1","display_name":"LSD1","score":0.9990000128746033},{"id":"https://openalex.org/keywords/acute-myeloid-leukemia","display_name":"acute myeloid leukemia","score":0.9959999918937683},{"id":"https://openalex.org/keywords/h3k27-acetylation","display_name":"H3K27 acetylation","score":0.9089999794960022},{"id":"https://openalex.org/keywords/cut-tag","display_name":"CUT&Tag","score":0.8640000224113464},{"id":"https://openalex.org/keywords/enhancers","display_name":"enhancers","score":0.7889999747276306},{"id":"https://openalex.org/keywords/promoter","display_name":"promoter","score":0.9890000224113464},{"id":"https://openalex.org/keywords/chromatin-accessibility","display_name":"chromatin accessibility","score":0.6269999742507935},{"id":"https://openalex.org/keywords/dual-targeting","display_name":"dual targeting","score":0.38600000739097595}],"concepts":[{"id":"https://openalex.org/C2780980858","wikidata":"https://www.wikidata.org/wiki/Q110022","display_name":"Dual (grammatical number)","level":2,"score":0.6528114080429077},{"id":"https://openalex.org/C2778729363","wikidata":"https://www.wikidata.org/wiki/Q11688946","display_name":"Myeloid leukemia","level":2,"score":0.6376669406890869},{"id":"https://openalex.org/C111936080","wikidata":"https://www.wikidata.org/wiki/Q913367","display_name":"Enhancer","level":4,"score":0.605707049369812},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.5289048552513123},{"id":"https://openalex.org/C45235069","wikidata":"https://www.wikidata.org/wiki/Q278425","display_name":"Table (database)","level":2,"score":0.4385008215904236},{"id":"https://openalex.org/C101762097","wikidata":"https://www.wikidata.org/wiki/Q224093","display_name":"Promoter","level":4,"score":0.428561270236969},{"id":"https://openalex.org/C93226319","wikidata":"https://www.wikidata.org/wiki/Q193137","display_name":"Differential (mechanical device)","level":2,"score":0.41797682642936707},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.37501823902130127},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3534170985221863},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.31819793581962585},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.27741679549217224},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.16319602727890015},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.1482798457145691},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.09702590107917786},{"id":"https://openalex.org/C86339819","wikidata":"https://www.wikidata.org/wiki/Q407384","display_name":"Transcription factor","level":3,"score":0.08916032314300537},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.05656501650810242},{"id":"https://openalex.org/C97355855","wikidata":"https://www.wikidata.org/wiki/Q11473","display_name":"Thermodynamics","level":1,"score":0.0},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.0},{"id":"https://openalex.org/C124952713","wikidata":"https://www.wikidata.org/wiki/Q8242","display_name":"Literature","level":1,"score":0.0},{"id":"https://openalex.org/C142362112","wikidata":"https://www.wikidata.org/wiki/Q735","display_name":"Art","level":0,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1158/1541-7786.23627422","doi":"https://doi.org/10.1158/1541-7786.23627422","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1541-7786.23627422","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},{"id":"doi:10.1158/1541-7786.23627422.v1","doi":"https://doi.org/10.1158/1541-7786.23627422.v1","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1158/1541-7786.23627422.v1","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},{"id":"pmh:oai:figshare.com:article/23627422","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/dataset/Supplementary_Table_6_from_Disruption_of_the_MYC_Superenhancer_Complex_by_Dual_Targeting_of_FLT3_and_LSD1_in_Acute_Myeloid_Leukemia/23627422","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dataset"}],"best_oa_location":{"id":"doi:10.1158/1541-7786.23627422","doi":"https://doi.org/10.1158/1541-7786.23627422","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1541-7786.23627422","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.8560000061988831,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":[],"abstract_inverted_index":{"Normalized":[0],"Read":[1],"Pileup":[2],"and":[3,18],"Differential":[4],"Enrichment":[5],"Clusters":[6],"of":[7],"MOLM13":[8],"H3K27Ac":[9],"CUT&Tag":[10],"(6":[11],"Hours":[12],"After":[13],"Drug":[14],"Treatment)":[15],"at":[16],"Enhancers":[17],"Promoters":[19]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2023-07-06T00:00:00"}