{"id":"https://openalex.org/W4383040541","doi":"https://doi.org/10.34172/jpe.2023.35205","title":"Association between seizure susceptibility with type and optimal dose of antihistamine in patients with a febrile seizure; A retrospective cohort study in Gorgan, Iran","display_name":"Association between seizure susceptibility with type and optimal dose of antihistamine in patients with a febrile seizure; A retrospective cohort study in Gorgan, Iran","publication_year":2023,"publication_date":"2023-07-04","ids":{"openalex":"https://openalex.org/W4383040541","doi":"https://doi.org/10.34172/jpe.2023.35205"},"language":"en","primary_location":{"id":"doi:10.34172/jpe.2023.35205","doi":"https://doi.org/10.34172/jpe.2023.35205","is_oa":true,"landing_page_url":"https://doi.org/10.34172/jpe.2023.35205","pdf_url":"https://jprevepi.com/Inpress/jpe-35205.pdf","source":{"id":"https://openalex.org/S4210220719","display_name":"Journal of Preventive Epidemiology","issn_l":"2476-3934","issn":["2476-3934"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj"],"host_organization":"https://openalex.org/P4310319026","host_organization_name":"Society of Diabetic Nephropathy Prevention","host_organization_lineage":["https://openalex.org/P4310319026"],"host_organization_lineage_names":["Society of Diabetic Nephropathy Prevention"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Preventive Epidemiology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://jprevepi.com/Inpress/jpe-35205.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5092391685","display_name":"Hossein Gorzin","orcid":"https://orcid.org/0000-0003-1588-5596","observed_orcids":["https://orcid.org/0000-0003-1588-5596"]},"institutions":[{"id":"https://openalex.org/I4210127922","display_name":"Golestan University of Medical Sciences","ror":"https://ror.org/03mcx2558","country_code":"IR","type":"education","lineage":["https://openalex.org/I4210127922"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Hossein Gorzin","raw_affiliation_strings":["Neonatal and Children\u2019s Health Research Center, Golestan University of Medical Sciences, Gorgan, Iran"],"raw_orcid":"https://orcid.org/0000-0003-1588-5596","affiliations":[{"raw_affiliation_string":"Neonatal and Children\u2019s Health Research Center, Golestan University of Medical Sciences, Gorgan, Iran","institution_ids":["https://openalex.org/I4210127922"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085677059","display_name":"Seyed Ahmad Hosseini","orcid":"https://orcid.org/0000-0001-6191-682X","observed_orcids":["https://orcid.org/0000-0001-6191-682X"]},"institutions":[{"id":"https://openalex.org/I4210127922","display_name":"Golestan University of Medical Sciences","ror":"https://ror.org/03mcx2558","country_code":"IR","type":"education","lineage":["https://openalex.org/I4210127922"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Seyed Ahmad Hosseini","raw_affiliation_strings":["Neonatal and Children\u2019s Health Research Center, Golestan University of Medical Sciences, Gorgan, Iran"],"raw_orcid":"https://orcid.org/0000-0001-6191-682X","affiliations":[{"raw_affiliation_string":"Neonatal and Children\u2019s Health Research Center, Golestan University of Medical Sciences, Gorgan, Iran","institution_ids":["https://openalex.org/I4210127922"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005485422","display_name":"Mousa Ghelichi-Ghojogh","orcid":"https://orcid.org/0000-0002-0726-5509","observed_orcids":["https://orcid.org/0000-0002-0726-5509"]},"institutions":[{"id":"https://openalex.org/I4210127922","display_name":"Golestan University of Medical Sciences","ror":"https://ror.org/03mcx2558","country_code":"IR","type":"education","lineage":["https://openalex.org/I4210127922"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Mousa Ghelichi-Ghojogh","raw_affiliation_strings":["Neonatal and Children\u2019s Health Research Center, Golestan University of Medical Sciences, Gorgan, Iran"],"raw_orcid":"https://orcid.org/0000-0002-0726-5509","affiliations":[{"raw_affiliation_string":"Neonatal and Children\u2019s Health Research Center, Golestan University of Medical Sciences, Gorgan, Iran","institution_ids":["https://openalex.org/I4210127922"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5092391686","display_name":"Edris Ghezeljeh","orcid":"https://orcid.org/0000-0001-7591-6951","observed_orcids":["https://orcid.org/0000-0001-7591-6951"]},"institutions":[{"id":"https://openalex.org/I4210127922","display_name":"Golestan University of Medical Sciences","ror":"https://ror.org/03mcx2558","country_code":"IR","type":"education","lineage":["https://openalex.org/I4210127922"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Edris Ghezeljeh","raw_affiliation_strings":["Neonatal and Children\u2019s Health Research Center, Golestan University of Medical Sciences, Gorgan, Iran"],"raw_orcid":"https://orcid.org/0000-0001-7591-6951","affiliations":[{"raw_affiliation_string":"Neonatal and Children\u2019s Health Research Center, Golestan University of Medical Sciences, Gorgan, Iran","institution_ids":["https://openalex.org/I4210127922"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5078426906","display_name":"Seyed Ali Aghapour","orcid":"https://orcid.org/0000-0002-8320-3414","observed_orcids":["https://orcid.org/0000-0002-8320-3414"]},"institutions":[{"id":"https://openalex.org/I4210127922","display_name":"Golestan University of Medical Sciences","ror":"https://ror.org/03mcx2558","country_code":"IR","type":"education","lineage":["https://openalex.org/I4210127922"]}],"countries":["IR"],"is_corresponding":true,"raw_author_name":"Seyed Ali Aghapour","raw_affiliation_strings":["Neonatal and Children\u2019s Health Research Center, Golestan University of Medical Sciences, Gorgan, Iran"],"raw_orcid":"https://orcid.org/0000-0002-8320-3414","affiliations":[{"raw_affiliation_string":"Neonatal and Children\u2019s Health Research Center, Golestan University of Medical Sciences, Gorgan, Iran","institution_ids":["https://openalex.org/I4210127922"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5078426906"],"corresponding_institution_ids":["https://openalex.org/I4210127922"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.11760412,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"9","issue":"2","first_page":"e35205","last_page":"e35205"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10094","display_name":"Epilepsy research and treatment","score":0.9854000210762024,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10094","display_name":"Epilepsy research and treatment","score":0.9854000210762024,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11117","display_name":"Drug-Induced Adverse Reactions","score":0.0032999999821186066,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11943","display_name":"Pharmacovigilance and Adverse Drug Reactions","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/3005","display_name":"Toxicology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/febrile-seizures","display_name":"febrile seizures","score":0.9919999837875366},{"id":"https://openalex.org/keywords/antihistamines","display_name":"antihistamines","score":0.9779999852180481},{"id":"https://openalex.org/keywords/first-generation-antihistamines","display_name":"first-generation antihistamines","score":0.9900000095367432},{"id":"https://openalex.org/keywords/second-generation-antihistamines","display_name":"second-generation antihistamines","score":1.0},{"id":"https://openalex.org/keywords/seizure-duration","display_name":"seizure duration","score":0.7350000143051147},{"id":"https://openalex.org/keywords/seizure-susceptibility","display_name":"seizure susceptibility","score":0.8679999709129333},{"id":"https://openalex.org/keywords/pediatric-fever","display_name":"pediatric fever","score":0.44999998807907104}],"concepts":[{"id":"https://openalex.org/C2776880894","wikidata":"https://www.wikidata.org/wiki/Q324089","display_name":"Antihistamine","level":2,"score":0.9775486588478088},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7934232950210571},{"id":"https://openalex.org/C167135981","wikidata":"https://www.wikidata.org/wiki/Q2146302","display_name":"Retrospective cohort study","level":2,"score":0.6164477467536926},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.5679574608802795},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.4958227574825287},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.37216755747795105},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3125872015953064}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.34172/jpe.2023.35205","doi":"https://doi.org/10.34172/jpe.2023.35205","is_oa":true,"landing_page_url":"https://doi.org/10.34172/jpe.2023.35205","pdf_url":"https://jprevepi.com/Inpress/jpe-35205.pdf","source":{"id":"https://openalex.org/S4210220719","display_name":"Journal of Preventive Epidemiology","issn_l":"2476-3934","issn":["2476-3934"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj"],"host_organization":"https://openalex.org/P4310319026","host_organization_name":"Society of Diabetic Nephropathy Prevention","host_organization_lineage":["https://openalex.org/P4310319026"],"host_organization_lineage_names":["Society of Diabetic Nephropathy Prevention"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Preventive Epidemiology","raw_type":"journal-article"},{"id":"pmh:oai:doaj.org/article:5c0fb7bf269b432e876887bc267c8901","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/5c0fb7bf269b432e876887bc267c8901","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of Preventive Epidemiology, Vol 9, Iss 2, Pp e35205-e35205 (2024)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.34172/jpe.2023.35205","doi":"https://doi.org/10.34172/jpe.2023.35205","is_oa":true,"landing_page_url":"https://doi.org/10.34172/jpe.2023.35205","pdf_url":"https://jprevepi.com/Inpress/jpe-35205.pdf","source":{"id":"https://openalex.org/S4210220719","display_name":"Journal of Preventive Epidemiology","issn_l":"2476-3934","issn":["2476-3934"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj"],"host_organization":"https://openalex.org/P4310319026","host_organization_name":"Society of Diabetic Nephropathy Prevention","host_organization_lineage":["https://openalex.org/P4310319026"],"host_organization_lineage_names":["Society of Diabetic Nephropathy Prevention"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Preventive Epidemiology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4383040541.pdf","grobid_xml":"https://content.openalex.org/works/W4383040541.grobid-xml"},"referenced_works_count":26,"referenced_works":["https://openalex.org/W14568608","https://openalex.org/W15269077","https://openalex.org/W1915723859","https://openalex.org/W2002750003","https://openalex.org/W2005441904","https://openalex.org/W2008166345","https://openalex.org/W2026286446","https://openalex.org/W2053641545","https://openalex.org/W2084685420","https://openalex.org/W2088606798","https://openalex.org/W2091389909","https://openalex.org/W2106502577","https://openalex.org/W2128620035","https://openalex.org/W2135954101","https://openalex.org/W2142258454","https://openalex.org/W2358631735","https://openalex.org/W2592605464","https://openalex.org/W2803690187","https://openalex.org/W2883405111","https://openalex.org/W2987950811","https://openalex.org/W2993303754","https://openalex.org/W2999992591","https://openalex.org/W4248548485","https://openalex.org/W4248646554","https://openalex.org/W4254660188","https://openalex.org/W4288400169"],"related_works":["https://openalex.org/W2002750003","https://openalex.org/W2987950811","https://openalex.org/W7098505671","https://openalex.org/W2135954101","https://openalex.org/W2803690187","https://openalex.org/W2999992591","https://openalex.org/W4256321708","https://openalex.org/W2142258454","https://openalex.org/W2883405111","https://openalex.org/W4404886704"],"abstract_inverted_index":{"Introduction:":[0],"Febrile":[1],"seizures":[2,222],"(FSs)":[3],"are":[4],"caused":[5],"by":[6],"the":[7,17,29,110,119,129,132,143,148,151,159,178,184,191,193,202,219,228,235,240,255],"simultaneous":[8],"consumption":[9],"of":[10,36,77,109,118,128,165,198,210,221,242,245,257],"first-":[11],"and":[12,34,43,72,79,95,102,131,138,212,223],"second-generation":[13,185],"antihistamines,":[14],"which":[15],"prolong":[16],"process":[18],"in":[19,38,60,63,90,142,158,177,234,247],"some":[20],"cases.":[21],"Objectives:":[22],"The":[23,65,106,163],"present":[24],"study":[25,48],"aimed":[26],"to":[27,57,183,190,254],"evaluate":[28],"relationship":[30,215],"between":[31,135,218],"seizure":[32,139,153,167,230],"susceptibility":[33],"type":[35],"antihistamines":[37],"patients":[39,111,120,194],"with":[40,54,195],"FS.":[41],"Patients":[42],"Methods:":[44],"This":[45],"retrospective":[46],"cohort":[47],"was":[49,88,112,124,140,155,173,216,232],"conducted":[50],"on":[51,82],"364":[52],"children":[53],"FS":[55],"admitted":[56],"Taleghani":[58],"Hospital":[59],"Gorgan,":[61],"Iran":[62],"2020.":[64],"subjects":[66],"were":[67,121],"selected":[68],"via":[69],"convenience":[70],"sampling":[71],"divided":[73],"into":[74],"two":[75],"groups":[76],"antihistamine":[78,144,160,180,199,224,237],"non-users":[80],"based":[81],"their":[83],"medical":[84],"files.":[85],"Data":[86],"analysis":[87],"performed":[89],"SPSS16":[91],"using":[92],"descriptive":[93],"statistics":[94],"chi-square,":[96],"independent":[97],"t-test,":[98],"Mann-Whitney":[99],"U":[100],"test,":[101],"relative":[103],"risk.":[104],"Results:":[105],"mean":[107,133,152,229],"age":[108,249],"22.77\u00b114.91":[113],"months":[114],"(6-60":[115],"months).":[116],"56.1%":[117],"male.":[122],"Antihistamine":[123],"prescribed":[125],"for":[126],"15.6%":[127],"subjects,":[130],"interval":[134],"fever":[136],"onset":[137],"shorter":[141],"group":[145,161,181,186],"(P=0.37).":[146],"On":[147],"other":[149],"hand,":[150],"duration":[154,231],"significantly":[156,207],"longer":[157,208,233],"(P=0.049).":[162],"risk":[164],"a":[166,196,206,213,258],"lasting":[168],"more":[169],"than":[170],"five":[171],"minutes":[172],"1.14":[174],"times":[175],"higher":[176],"first-generation":[179,236],"compared":[182],"(P=0.078).":[187],"Conclusion:":[188],"According":[189],"results,":[192],"history":[197],"use":[200,241],"during":[201],"febrile":[203],"period":[204,209],"experienced":[205],"seizure,":[211],"significant":[214],"observed":[217],"severity":[220],"use.":[225],"In":[226],"addition,":[227],"group.":[238],"Therefore,":[239],"this":[243,248],"class":[244],"drugs":[246],"range":[250],"should":[251],"be":[252],"limited":[253],"prescription":[256],"specialist.":[259]},"counts_by_year":[],"updated_date":"2026-10-14T16:39:01.820549","created_date":"2023-07-04T00:00:00"}
