{"id":"https://openalex.org/W4382940804","doi":"https://doi.org/10.3390/jof9070722","title":"Development of an Imaging Flow Cytometry Method for Fungal Cytological Profiling and Its Potential Application in Antifungal Drug Development","display_name":"Development of an Imaging Flow Cytometry Method for Fungal Cytological Profiling and Its Potential Application in Antifungal Drug Development","publication_year":2023,"publication_date":"2023-06-30","ids":{"openalex":"https://openalex.org/W4382940804","doi":"https://doi.org/10.3390/jof9070722","pmid":"https://pubmed.ncbi.nlm.nih.gov/37504711","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/10381375"},"language":"en","primary_location":{"id":"doi:10.3390/jof9070722","doi":"https://doi.org/10.3390/jof9070722","is_oa":true,"landing_page_url":"https://doi.org/10.3390/jof9070722","pdf_url":"https://www.mdpi.com/2309-608X/9/7/722/pdf?version=1688386493","source":{"id":"https://openalex.org/S2737643958","display_name":"Journal of Fungi","issn_l":"2309-608X","issn":["2309-608X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-20","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Fungi","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/2309-608X/9/7/722/pdf?version=1688386493","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5082615438","display_name":"Courtney L. McMahon","orcid":"https://orcid.org/0000-0002-3523-6529","observed_orcids":["https://orcid.org/0000-0002-3523-6529"]},"institutions":[{"id":"https://openalex.org/I45438204","display_name":"The University of Texas at San Antonio","ror":"https://ror.org/01kd65564","country_code":"US","type":"education","lineage":["https://openalex.org/I45438204"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Courtney L. McMahon","raw_affiliation_strings":["Department of Molecular Microbiology and Immunology and South Texas Center for Emerging Infectious Diseases, The University of Texas at San Antonio, San Antonio, TX 78249, USA"],"raw_orcid":"https://orcid.org/0000-0002-3523-6529","affiliations":[{"raw_affiliation_string":"Department of Molecular Microbiology and Immunology and South Texas Center for Emerging Infectious Diseases, The University of Texas at San Antonio, San Antonio, TX 78249, USA","institution_ids":["https://openalex.org/I45438204"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082995197","display_name":"Marisol Esqueda","orcid":"https://orcid.org/0000-0002-2182-2105","observed_orcids":["https://orcid.org/0000-0002-2182-2105"]},"institutions":[{"id":"https://openalex.org/I45438204","display_name":"The University of Texas at San Antonio","ror":"https://ror.org/01kd65564","country_code":"US","type":"education","lineage":["https://openalex.org/I45438204"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Marisol Esqueda","raw_affiliation_strings":["Department of Molecular Microbiology and Immunology and South Texas Center for Emerging Infectious Diseases, The University of Texas at San Antonio, San Antonio, TX 78249, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Microbiology and Immunology and South Texas Center for Emerging Infectious Diseases, The University of Texas at San Antonio, San Antonio, TX 78249, USA","institution_ids":["https://openalex.org/I45438204"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050645487","display_name":"Jieh\u2010Juen Yu","orcid":"https://orcid.org/0000-0001-8901-3366","observed_orcids":["https://orcid.org/0000-0001-8901-3366"]},"institutions":[{"id":"https://openalex.org/I45438204","display_name":"The University of Texas at San Antonio","ror":"https://ror.org/01kd65564","country_code":"US","type":"education","lineage":["https://openalex.org/I45438204"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jieh-Juen Yu","raw_affiliation_strings":["Department of Molecular Microbiology and Immunology and South Texas Center for Emerging Infectious Diseases, The University of Texas at San Antonio, San Antonio, TX 78249, USA"],"raw_orcid":"https://orcid.org/0000-0001-8901-3366","affiliations":[{"raw_affiliation_string":"Department of Molecular Microbiology and Immunology and South Texas Center for Emerging Infectious Diseases, The University of Texas at San Antonio, San Antonio, TX 78249, USA","institution_ids":["https://openalex.org/I45438204"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012467609","display_name":"Gina Wall","orcid":"https://orcid.org/0000-0002-0573-149X","observed_orcids":["https://orcid.org/0000-0002-0573-149X"]},"institutions":[{"id":"https://openalex.org/I45438204","display_name":"The University of Texas at San Antonio","ror":"https://ror.org/01kd65564","country_code":"US","type":"education","lineage":["https://openalex.org/I45438204"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gina Wall","raw_affiliation_strings":["Department of Molecular Microbiology and Immunology and South Texas Center for Emerging Infectious Diseases, The University of Texas at San Antonio, San Antonio, TX 78249, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Microbiology and Immunology and South Texas Center for Emerging Infectious Diseases, The University of Texas at San Antonio, San Antonio, TX 78249, USA","institution_ids":["https://openalex.org/I45438204"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033304717","display_name":"Jes\u00fas A. Romo","orcid":"https://orcid.org/0000-0002-1683-2288","observed_orcids":["https://orcid.org/0000-0002-1683-2288"]},"institutions":[{"id":"https://openalex.org/I45438204","display_name":"The University of Texas at San Antonio","ror":"https://ror.org/01kd65564","country_code":"US","type":"education","lineage":["https://openalex.org/I45438204"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jesus A. Romo","raw_affiliation_strings":["Department of Molecular Microbiology and Immunology and South Texas Center for Emerging Infectious Diseases, The University of Texas at San Antonio, San Antonio, TX 78249, USA"],"raw_orcid":"https://orcid.org/0000-0002-1683-2288","affiliations":[{"raw_affiliation_string":"Department of Molecular Microbiology and Immunology and South Texas Center for Emerging Infectious Diseases, The University of Texas at San Antonio, San Antonio, TX 78249, USA","institution_ids":["https://openalex.org/I45438204"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030104677","display_name":"Taissa Vieira Machado Vila","orcid":"https://orcid.org/0000-0001-5600-4367","observed_orcids":["https://orcid.org/0000-0001-5600-4367"]},"institutions":[{"id":"https://openalex.org/I45438204","display_name":"The University of Texas at San Antonio","ror":"https://ror.org/01kd65564","country_code":"US","type":"education","lineage":["https://openalex.org/I45438204"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Taissa Vila","raw_affiliation_strings":["Department of Molecular Microbiology and Immunology and South Texas Center for Emerging Infectious Diseases, The University of Texas at San Antonio, San Antonio, TX 78249, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Microbiology and Immunology and South Texas Center for Emerging Infectious Diseases, The University of Texas at San Antonio, San Antonio, TX 78249, USA","institution_ids":["https://openalex.org/I45438204"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102166080","display_name":"Ashok Kumar Chaturvedi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I45438204","display_name":"The University of Texas at San Antonio","ror":"https://ror.org/01kd65564","country_code":"US","type":"education","lineage":["https://openalex.org/I45438204"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ashok Chaturvedi","raw_affiliation_strings":["Department of Molecular Microbiology and Immunology and South Texas Center for Emerging Infectious Diseases, The University of Texas at San Antonio, San Antonio, TX 78249, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Microbiology and Immunology and South Texas Center for Emerging Infectious Diseases, The University of Texas at San Antonio, San Antonio, TX 78249, USA","institution_ids":["https://openalex.org/I45438204"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022852723","display_name":"Jose Luis Lopez-Ribot","orcid":"https://orcid.org/0000-0003-1992-3270","observed_orcids":["https://orcid.org/0000-0003-1992-3270"]},"institutions":[{"id":"https://openalex.org/I45438204","display_name":"The University of Texas at San Antonio","ror":"https://ror.org/01kd65564","country_code":"US","type":"education","lineage":["https://openalex.org/I45438204"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jose L. Lopez-Ribot","raw_affiliation_strings":["Department of Molecular Microbiology and Immunology and South Texas Center for Emerging Infectious Diseases, The University of Texas at San Antonio, San Antonio, TX 78249, USA"],"raw_orcid":"https://orcid.org/0000-0003-1992-3270","affiliations":[{"raw_affiliation_string":"Department of Molecular Microbiology and Immunology and South Texas Center for Emerging Infectious Diseases, The University of Texas at San Antonio, San Antonio, TX 78249, USA","institution_ids":["https://openalex.org/I45438204"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068233995","display_name":"Floyd L. Wormley","orcid":"https://orcid.org/0000-0001-9290-3925","observed_orcids":["https://orcid.org/0000-0001-9290-3925"]},"institutions":[{"id":"https://openalex.org/I45438204","display_name":"The University of Texas at San Antonio","ror":"https://ror.org/01kd65564","country_code":"US","type":"education","lineage":["https://openalex.org/I45438204"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Floyd Wormley","raw_affiliation_strings":["Department of Molecular Microbiology and Immunology and South Texas Center for Emerging Infectious Diseases, The University of Texas at San Antonio, San Antonio, TX 78249, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Microbiology and Immunology and South Texas Center for Emerging Infectious Diseases, The University of Texas at San Antonio, San Antonio, TX 78249, USA","institution_ids":["https://openalex.org/I45438204"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5003041501","display_name":"Chiung-Yu Hung","orcid":"https://orcid.org/0000-0003-1091-3420","observed_orcids":["https://orcid.org/0000-0003-1091-3420"]},"institutions":[{"id":"https://openalex.org/I45438204","display_name":"The University of Texas at San Antonio","ror":"https://ror.org/01kd65564","country_code":"US","type":"education","lineage":["https://openalex.org/I45438204"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Chiung-Yu Hung","raw_affiliation_strings":["Department of Molecular Microbiology and Immunology and South Texas Center for Emerging Infectious Diseases, The University of Texas at San Antonio, San Antonio, TX 78249, USA"],"raw_orcid":"https://orcid.org/0000-0003-1091-3420","affiliations":[{"raw_affiliation_string":"Department of Molecular Microbiology and Immunology and South Texas Center for Emerging Infectious Diseases, The University of Texas at San Antonio, San Antonio, TX 78249, USA","institution_ids":["https://openalex.org/I45438204"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5003041501"],"corresponding_institution_ids":["https://openalex.org/I45438204"],"apc_list":{"value":2200,"currency":"CHF","value_usd":2447},"apc_paid":{"value":2200,"currency":"CHF","value_usd":2447},"fwci":1.5713,"has_fulltext":true,"cited_by_count":13,"citation_normalized_percentile":{"value":0.82110499,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":97,"max":98},"biblio":{"volume":"9","issue":"7","first_page":"722","last_page":"722"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.5820000171661377,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.5820000171661377,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10150","display_name":"Antifungal resistance and susceptibility","score":0.4113999903202057,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10497","display_name":"Fungal and yeast genetics research","score":0.001500000013038516,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/imaging-flow-cytometry","display_name":"imaging flow cytometry","score":0.984000027179718},{"id":"https://openalex.org/keywords/antifungal-drug-development","display_name":"antifungal drug development","score":0.9369999766349792},{"id":"https://openalex.org/keywords/antifungal-screening","display_name":"antifungal screening","score":0.699999988079071},{"id":"https://openalex.org/keywords/candida-albicans","display_name":"Candida albicans","score":0.8949999809265137},{"id":"https://openalex.org/keywords/cryptococcus-neoformans","display_name":"Cryptococcus neoformans","score":0.9980000257492065},{"id":"https://openalex.org/keywords/calcofluor-white","display_name":"calcofluor white","score":0.8920000195503235},{"id":"https://openalex.org/keywords/fluconazole","display_name":"fluconazole","score":0.8270000219345093},{"id":"https://openalex.org/keywords/amphotericin-b","display_name":"amphotericin B","score":0.9940000176429749},{"id":"https://openalex.org/keywords/caspofungin","display_name":"caspofungin","score":0.9990000128746033},{"id":"https://openalex.org/keywords/fungal-cell-wall","display_name":"fungal cell wall","score":0.5699999928474426},{"id":"https://openalex.org/keywords/fungal-membranes","display_name":"fungal membranes","score":0.6539999842643738},{"id":"https://openalex.org/keywords/phenotypic-profiling","display_name":"phenotypic profiling","score":0.6240000128746033}],"concepts":[{"id":"https://openalex.org/C2777893358","wikidata":"https://www.wikidata.org/wiki/Q131924","display_name":"Cryptococcus neoformans","level":2,"score":0.8454227447509766},{"id":"https://openalex.org/C2780402444","wikidata":"https://www.wikidata.org/wiki/Q420875","display_name":"Caspofungin","level":4,"score":0.7765709757804871},{"id":"https://openalex.org/C2991737395","wikidata":"https://www.wikidata.org/wiki/Q578726","display_name":"Antifungal drug","level":3,"score":0.6605751514434814},{"id":"https://openalex.org/C6555983","wikidata":"https://www.wikidata.org/wiki/Q7181398","display_name":"Phenotypic screening","level":4,"score":0.5975292325019836},{"id":"https://openalex.org/C2780917455","wikidata":"https://www.wikidata.org/wiki/Q310443","display_name":"Candida albicans","level":2,"score":0.5839143991470337},{"id":"https://openalex.org/C2780651595","wikidata":"https://www.wikidata.org/wiki/Q411478","display_name":"Fluconazole","level":3,"score":0.5716386437416077},{"id":"https://openalex.org/C553184892","wikidata":"https://www.wikidata.org/wiki/Q1141429","display_name":"Flow cytometry","level":2,"score":0.533766508102417},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5280507206916809},{"id":"https://openalex.org/C2779629538","wikidata":"https://www.wikidata.org/wiki/Q412223","display_name":"Amphotericin B","level":3,"score":0.4794943928718567},{"id":"https://openalex.org/C187191949","wikidata":"https://www.wikidata.org/wiki/Q1138496","display_name":"Profiling (computer programming)","level":2,"score":0.443361759185791},{"id":"https://openalex.org/C2779413141","wikidata":"https://www.wikidata.org/wiki/Q1470140","display_name":"Cryptococcosis","level":2,"score":0.4289744794368744},{"id":"https://openalex.org/C64903051","wikidata":"https://www.wikidata.org/wiki/Q2198549","display_name":"Drug development","level":3,"score":0.42402833700180054},{"id":"https://openalex.org/C127716648","wikidata":"https://www.wikidata.org/wiki/Q104053","display_name":"Phenotype","level":3,"score":0.420849472284317},{"id":"https://openalex.org/C2779548794","wikidata":"https://www.wikidata.org/wiki/Q578726","display_name":"Antifungal","level":2,"score":0.387408971786499},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.3616163730621338},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3491206765174866},{"id":"https://openalex.org/C2780035454","wikidata":"https://www.wikidata.org/wiki/Q8386","display_name":"Drug","level":2,"score":0.3401852548122406},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.1541808843612671},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.1377871334552765},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.13541701436042786},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.08686131238937378},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.3390/jof9070722","doi":"https://doi.org/10.3390/jof9070722","is_oa":true,"landing_page_url":"https://doi.org/10.3390/jof9070722","pdf_url":"https://www.mdpi.com/2309-608X/9/7/722/pdf?version=1688386493","source":{"id":"https://openalex.org/S2737643958","display_name":"Journal of Fungi","issn_l":"2309-608X","issn":["2309-608X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-20","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Fungi","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:10381375","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10381375","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10381375/pdf/jof-09-00722.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Fungi (Basel)","raw_type":"Text"},{"id":"pmid:37504711","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37504711","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of fungi (Basel, Switzerland)","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:dc04aea201664b80b5df3b7b6389d2f9","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/dc04aea201664b80b5df3b7b6389d2f9","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of Fungi, Vol 9, Iss 7, p 722 (2023)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3390/jof9070722","doi":"https://doi.org/10.3390/jof9070722","is_oa":true,"landing_page_url":"https://doi.org/10.3390/jof9070722","pdf_url":"https://www.mdpi.com/2309-608X/9/7/722/pdf?version=1688386493","source":{"id":"https://openalex.org/S2737643958","display_name":"Journal of Fungi","issn_l":"2309-608X","issn":["2309-608X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-20","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Fungi","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.5683000087738037}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.7200000286102295}],"study_designs":[],"awards":[{"id":"https://openalex.org/G404318650","display_name":"Screening a Target-Based Repurposing Library for Activity against Fungal Pathogens and Subsequent Preclinical Development of Leading Candidates","funder_award_id":"R33AI140823","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G7304735917","display_name":"Development of a multivalent vaccine against Coccidioides infection","funder_award_id":"R01AI135005","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G7309172719","display_name":"Apply an imaging flow cytometry method to screen chemical libraries for identifying and repurposing novel drugs against coccidioidomycosis","funder_award_id":"R21AI149015","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G7393155948","display_name":"UTSA RISE Research Training Program","funder_award_id":"R25GM060655","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G9000887647","display_name":"SA-CCRC-Development of Therapeutics and Vaccines Against Coccidioidomycosis.","funder_award_id":"U19AI166761","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"},{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4382940804.pdf","grobid_xml":"https://content.openalex.org/works/W4382940804.grobid-xml"},"referenced_works_count":54,"referenced_works":["https://openalex.org/W246015746","https://openalex.org/W859864464","https://openalex.org/W1577270869","https://openalex.org/W1585072075","https://openalex.org/W1780057449","https://openalex.org/W1911734524","https://openalex.org/W1991149656","https://openalex.org/W1993669821","https://openalex.org/W2003969287","https://openalex.org/W2004389050","https://openalex.org/W2022159036","https://openalex.org/W2033887346","https://openalex.org/W2052931063","https://openalex.org/W2054323370","https://openalex.org/W2089846445","https://openalex.org/W2091708067","https://openalex.org/W2102739518","https://openalex.org/W2109092583","https://openalex.org/W2116830693","https://openalex.org/W2117206304","https://openalex.org/W2128575896","https://openalex.org/W2128917111","https://openalex.org/W2130118048","https://openalex.org/W2135182325","https://openalex.org/W2144963196","https://openalex.org/W2146698584","https://openalex.org/W2147187090","https://openalex.org/W2148427024","https://openalex.org/W2160204310","https://openalex.org/W2261930170","https://openalex.org/W2295918748","https://openalex.org/W2314322923","https://openalex.org/W2409377496","https://openalex.org/W2411610827","https://openalex.org/W2460598206","https://openalex.org/W2498090354","https://openalex.org/W2518684956","https://openalex.org/W2529198584","https://openalex.org/W2555013411","https://openalex.org/W2584251723","https://openalex.org/W2597632059","https://openalex.org/W2615277755","https://openalex.org/W2767753889","https://openalex.org/W2795884050","https://openalex.org/W2885698573","https://openalex.org/W2897675706","https://openalex.org/W2899359448","https://openalex.org/W2911738685","https://openalex.org/W2917702355","https://openalex.org/W2953152748","https://openalex.org/W2979054781","https://openalex.org/W2999574124","https://openalex.org/W3006793634","https://openalex.org/W3034781784"],"related_works":["https://openalex.org/W2750980561","https://openalex.org/W2018916418","https://openalex.org/W3130440929","https://openalex.org/W1891149729","https://openalex.org/W2028964971","https://openalex.org/W66648161","https://openalex.org/W2059303071","https://openalex.org/W3202769961","https://openalex.org/W4390411627","https://openalex.org/W7161048717"],"abstract_inverted_index":{"Automated":[0],"imaging":[1,56],"techniques":[2],"have":[3,42,161],"been":[4],"in":[5,181],"increasing":[6],"demand":[7],"for":[8,49,170],"the":[9,22,83,136,171],"more":[10],"advanced":[11],"analysis":[12],"and":[13,32,78,86,111,156,166],"efficient":[14],"characterization":[15,173],"of":[16,21,38,66,91,103,118,124,139,174],"cellular":[17],"phenotypes.":[18],"The":[19],"success":[20],"image-based":[23],"profiling":[24,52],"method":[25,48,169],"hinges":[26],"on":[27],"assays":[28],"that":[29,59],"can":[30,60],"rapidly":[31],"simultaneously":[33],"capture":[34],"a":[35,67,115,143,163],"wide":[36],"range":[37],"phenotypic":[39,172],"features.":[40],"We":[41,99],"developed":[43,162],"an":[44,55],"automated":[45],"image":[46],"acquisition":[47],"fungal":[50,69,104,175],"cytological":[51],"(FCP)":[53],"using":[54,96],"flow":[57],"cytometer":[58],"objectively":[61],"measure":[62],"over":[63],"250":[64],"features":[65],"single":[68,92],"cell.":[70],"Fungal":[71],"cells":[72,93,105],"were":[73,94],"labeled":[74],"with":[75,107,114,127,149,178],"calcofluor":[76],"white":[77],"FM4-64FX,":[79],"which":[80],"bind":[81],"to":[82,120,146],"cell":[84],"wall":[85],"lipophilic":[87],"membrane,":[88],"respectively.":[89],"Images":[90],"analyzed":[95],"IDEAS\u00ae":[97],"software.":[98],"first":[100],"acquired":[101],"FCPs":[102],"treated":[106],"fluconazole,":[108],"amphotericin":[109],"B,":[110],"caspofungin,":[112],"each":[113],"distinct":[116],"mode":[117],"action,":[119],"establish":[121],"FCP":[122],"databases":[123],"profiles":[125],"associated":[126],"specific":[128],"antifungal":[129,151,182],"treatment.":[130],"Once":[131],"fully":[132],"established,":[133],"we":[134,160],"investigated":[135],"potential":[137,179],"application":[138],"this":[140],"technique":[141],"as":[142],"screening":[144],"methodology":[145],"identify":[147],"compounds":[148],"novel":[150,167],"activity":[152],"against":[153],"Candida":[154],"albicans":[155],"Cryptococcus":[157],"neoformans.":[158],"Altogether,":[159],"rapid,":[164],"powerful,":[165],"image-profiling":[168],"cells,":[176],"also":[177],"applications":[180],"drug":[183],"development.":[184]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":4}],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2023-07-04T00:00:00"}