{"id":"https://openalex.org/W4382919370","doi":"https://doi.org/10.1097/hc9.0000000000000183","title":"Incidence of hepatocellular carcinoma in nonalcoholic fatty liver disease without cirrhosis or advanced liver fibrosis","display_name":"Incidence of hepatocellular carcinoma in nonalcoholic fatty liver disease without cirrhosis or advanced liver fibrosis","publication_year":2023,"publication_date":"2023-07-01","ids":{"openalex":"https://openalex.org/W4382919370","doi":"https://doi.org/10.1097/hc9.0000000000000183","pmid":"https://pubmed.ncbi.nlm.nih.gov/37395730","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/10319365"},"language":"en","primary_location":{"id":"doi:10.1097/hc9.0000000000000183","doi":"https://doi.org/10.1097/hc9.0000000000000183","is_oa":true,"landing_page_url":"https://doi.org/10.1097/hc9.0000000000000183","pdf_url":null,"source":{"id":"https://openalex.org/S4210228550","display_name":"Hepatology Communications","issn_l":"2471-254X","issn":["2471-254X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-20","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Hepatology Communications","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1097/hc9.0000000000000183","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5061941420","display_name":"Jaideep Behari","orcid":"https://orcid.org/0000-0001-8077-5137","observed_orcids":["https://orcid.org/0000-0001-8077-5137"]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]},{"id":"https://openalex.org/I4210128526","display_name":"UPMC Hillman Cancer Center","ror":"https://ror.org/03bw34a45","country_code":"US","type":"facility","lineage":["https://openalex.org/I170201317","https://openalex.org/I4210128526"]},{"id":"https://openalex.org/I4210134769","display_name":"University of Pittsburgh Medical Center","ror":"https://ror.org/04ehecz88","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210098814","https://openalex.org/I4210134769"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Jaideep Behari","raw_affiliation_strings":["Division of Cancer Control and Population Sciences, UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania, USA","Division of Gastroenterology, Department of Medicine, Hepatology and Nutrition, School of Medicine, Pittsburgh, Pennsylvania, USA","Pittsburgh Liver Research Center, University of Pittsburgh, Pittsburgh, Pennsylvania, USA"],"raw_orcid":"https://orcid.org/0000-0001-8077-5137","affiliations":[{"raw_affiliation_string":"Division of Cancer Control and Population Sciences, UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania, USA","institution_ids":["https://openalex.org/I4210128526","https://openalex.org/I4210134769"]},{"raw_affiliation_string":"Division of Gastroenterology, Department of Medicine, Hepatology and Nutrition, School of Medicine, Pittsburgh, Pennsylvania, USA","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"Pittsburgh Liver Research Center, University of Pittsburgh, Pittsburgh, Pennsylvania, USA","institution_ids":["https://openalex.org/I170201317"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084122008","display_name":"Amir Gougol","orcid":"https://orcid.org/0009-0001-7346-2121","observed_orcids":["https://orcid.org/0009-0001-7346-2121"]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Amir Gougol","raw_affiliation_strings":["Division of Gastroenterology, Department of Medicine, Hepatology and Nutrition, School of Medicine, Pittsburgh, Pennsylvania, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Gastroenterology, Department of Medicine, Hepatology and Nutrition, School of Medicine, Pittsburgh, Pennsylvania, USA","institution_ids":["https://openalex.org/I170201317"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063230233","display_name":"Renwei Wang","orcid":"https://orcid.org/0000-0001-8871-7054","observed_orcids":["https://orcid.org/0000-0001-8871-7054"]},"institutions":[{"id":"https://openalex.org/I4210128526","display_name":"UPMC Hillman Cancer Center","ror":"https://ror.org/03bw34a45","country_code":"US","type":"facility","lineage":["https://openalex.org/I170201317","https://openalex.org/I4210128526"]},{"id":"https://openalex.org/I4210134769","display_name":"University of Pittsburgh Medical Center","ror":"https://ror.org/04ehecz88","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210098814","https://openalex.org/I4210134769"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Renwei Wang","raw_affiliation_strings":["Division of Cancer Control and Population Sciences, UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cancer Control and Population Sciences, UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania, USA","institution_ids":["https://openalex.org/I4210128526","https://openalex.org/I4210134769"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072644863","display_name":"Hung Nguyen Luu","orcid":"https://orcid.org/0000-0002-2172-1849","observed_orcids":["https://orcid.org/0000-0002-2172-1849"]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]},{"id":"https://openalex.org/I4210128526","display_name":"UPMC Hillman Cancer Center","ror":"https://ror.org/03bw34a45","country_code":"US","type":"facility","lineage":["https://openalex.org/I170201317","https://openalex.org/I4210128526"]},{"id":"https://openalex.org/I4210134769","display_name":"University of Pittsburgh Medical Center","ror":"https://ror.org/04ehecz88","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210098814","https://openalex.org/I4210134769"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hung N. Luu","raw_affiliation_strings":["Department of Epidemiology, School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA","Division of Cancer Control and Population Sciences, UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Epidemiology, School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"Division of Cancer Control and Population Sciences, UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania, USA","institution_ids":["https://openalex.org/I4210128526","https://openalex.org/I4210134769"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004659680","display_name":"Pedram Paragomi","orcid":"https://orcid.org/0000-0002-5471-4979","observed_orcids":["https://orcid.org/0000-0002-5471-4979"]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]},{"id":"https://openalex.org/I4210128526","display_name":"UPMC Hillman Cancer Center","ror":"https://ror.org/03bw34a45","country_code":"US","type":"facility","lineage":["https://openalex.org/I170201317","https://openalex.org/I4210128526"]},{"id":"https://openalex.org/I4210134769","display_name":"University of Pittsburgh Medical Center","ror":"https://ror.org/04ehecz88","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210098814","https://openalex.org/I4210134769"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Pedram Paragomi","raw_affiliation_strings":["Department of Epidemiology, School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA","Division of Cancer Control and Population Sciences, UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Epidemiology, School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"Division of Cancer Control and Population Sciences, UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania, USA","institution_ids":["https://openalex.org/I4210128526","https://openalex.org/I4210134769"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035258974","display_name":"Yi\u2010Chuan Yu","orcid":"https://orcid.org/0000-0002-8215-3144","observed_orcids":["https://orcid.org/0000-0002-8215-3144"]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]},{"id":"https://openalex.org/I4210128526","display_name":"UPMC Hillman Cancer Center","ror":"https://ror.org/03bw34a45","country_code":"US","type":"facility","lineage":["https://openalex.org/I170201317","https://openalex.org/I4210128526"]},{"id":"https://openalex.org/I4210134769","display_name":"University of Pittsburgh Medical Center","ror":"https://ror.org/04ehecz88","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210098814","https://openalex.org/I4210134769"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Yi-Chuan Yu","raw_affiliation_strings":["Department of Epidemiology, School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA","Division of Cancer Control and Population Sciences, UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Epidemiology, School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"Division of Cancer Control and Population Sciences, UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania, USA","institution_ids":["https://openalex.org/I4210128526","https://openalex.org/I4210134769"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086527996","display_name":"Michele Molinari","orcid":"https://orcid.org/0000-0002-9763-6253","observed_orcids":["https://orcid.org/0000-0002-9763-6253"]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michele Molinari","raw_affiliation_strings":["Department of Surgery, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA"],"raw_orcid":"https://orcid.org/0000-0002-9763-6253","affiliations":[{"raw_affiliation_string":"Department of Surgery, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA","institution_ids":["https://openalex.org/I170201317"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042823258","display_name":"Kapil B. Chopra","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kapil Chopra","raw_affiliation_strings":["Division of Gastroenterology, Department of Medicine, Hepatology and Nutrition, School of Medicine, Pittsburgh, Pennsylvania, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Gastroenterology, Department of Medicine, Hepatology and Nutrition, School of Medicine, Pittsburgh, Pennsylvania, USA","institution_ids":["https://openalex.org/I170201317"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004401265","display_name":"Shahid M. Malik","orcid":"https://orcid.org/0009-0007-9274-999X","observed_orcids":["https://orcid.org/0009-0007-9274-999X"]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shahid M. Malik","raw_affiliation_strings":["Division of Gastroenterology, Department of Medicine, Hepatology and Nutrition, School of Medicine, Pittsburgh, Pennsylvania, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Gastroenterology, Department of Medicine, Hepatology and Nutrition, School of Medicine, Pittsburgh, Pennsylvania, USA","institution_ids":["https://openalex.org/I170201317"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051148693","display_name":"David A. Geller","orcid":"https://orcid.org/0000-0003-0735-1068","observed_orcids":["https://orcid.org/0000-0003-0735-1068"]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David Geller","raw_affiliation_strings":["Department of Surgery, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA","Pittsburgh Liver Research Center, University of Pittsburgh, Pittsburgh, Pennsylvania, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"Pittsburgh Liver Research Center, University of Pittsburgh, Pittsburgh, Pennsylvania, USA","institution_ids":["https://openalex.org/I170201317"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5101957215","display_name":"Jian\u2010Min Yuan","orcid":"https://orcid.org/0000-0002-7664-7084","observed_orcids":["https://orcid.org/0000-0002-7664-7084"]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]},{"id":"https://openalex.org/I4210128526","display_name":"UPMC Hillman Cancer Center","ror":"https://ror.org/03bw34a45","country_code":"US","type":"facility","lineage":["https://openalex.org/I170201317","https://openalex.org/I4210128526"]},{"id":"https://openalex.org/I4210134769","display_name":"University of Pittsburgh Medical Center","ror":"https://ror.org/04ehecz88","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210098814","https://openalex.org/I4210134769"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Jian-Min Yuan","raw_affiliation_strings":["Department of Epidemiology, School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA","Division of Cancer Control and Population Sciences, UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania, USA","Pittsburgh Liver Research Center, University of Pittsburgh, Pittsburgh, Pennsylvania, USA"],"raw_orcid":"https://orcid.org/0000-0002-7664-7084","affiliations":[{"raw_affiliation_string":"Department of Epidemiology, School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"Division of Cancer Control and Population Sciences, UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania, USA","institution_ids":["https://openalex.org/I4210128526","https://openalex.org/I4210134769"]},{"raw_affiliation_string":"Pittsburgh Liver Research Center, University of Pittsburgh, Pittsburgh, Pennsylvania, USA","institution_ids":["https://openalex.org/I170201317"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5035258974","https://openalex.org/A5061941420","https://openalex.org/A5101957215"],"corresponding_institution_ids":["https://openalex.org/I170201317","https://openalex.org/I4210128526","https://openalex.org/I4210134769"],"apc_list":{"value":2700,"currency":"USD","value_usd":2700},"apc_paid":{"value":2700,"currency":"USD","value_usd":2700},"fwci":4.6001,"has_fulltext":true,"cited_by_count":38,"citation_normalized_percentile":{"value":0.96536889,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"7","issue":"7","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10073","display_name":"Hepatocellular Carcinoma Treatment and Prognosis","score":0.4982999861240387,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10073","display_name":"Hepatocellular Carcinoma Treatment and Prognosis","score":0.4982999861240387,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10351","display_name":"Liver Disease Diagnosis and Treatment","score":0.48829999566078186,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10966","display_name":"Liver physiology and pathology","score":0.00139999995008111,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hepatocellular-carcinoma","display_name":"hepatocellular carcinoma","score":0.996999979019165},{"id":"https://openalex.org/keywords/non-alcoholic-fatty-liver-disease","display_name":"non-alcoholic fatty liver disease","score":0.9940000176429749},{"id":"https://openalex.org/keywords/liver-cirrhosis","display_name":"liver cirrhosis","score":0.796999990940094},{"id":"https://openalex.org/keywords/liver-fibrosis","display_name":"liver fibrosis","score":0.9020000100135803},{"id":"https://openalex.org/keywords/fib-4-index","display_name":"FIB-4","score":0.8500000238418579},{"id":"https://openalex.org/keywords/cancer-incidence","display_name":"cancer incidence","score":0.8700000047683716},{"id":"https://openalex.org/keywords/advanced-fibrosis","display_name":"advanced fibrosis","score":0.4860000014305115}],"concepts":[{"id":"https://openalex.org/C2777214474","wikidata":"https://www.wikidata.org/wiki/Q147778","display_name":"Cirrhosis","level":2,"score":0.8803365230560303},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8551499247550964},{"id":"https://openalex.org/C2778019345","wikidata":"https://www.wikidata.org/wiki/Q1148337","display_name":"Hepatocellular carcinoma","level":2,"score":0.8023021221160889},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7460957765579224},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.7304480075836182},{"id":"https://openalex.org/C2776954865","wikidata":"https://www.wikidata.org/wiki/Q1546498","display_name":"Nonalcoholic fatty liver disease","level":4,"score":0.7089081406593323},{"id":"https://openalex.org/C61511704","wikidata":"https://www.wikidata.org/wiki/Q1671857","display_name":"Incidence (geometry)","level":2,"score":0.6443428993225098},{"id":"https://openalex.org/C2780559512","wikidata":"https://www.wikidata.org/wiki/Q605709","display_name":"Fibrosis","level":2,"score":0.4354970455169678},{"id":"https://openalex.org/C2779102576","wikidata":"https://www.wikidata.org/wiki/Q5113984","display_name":"Chronic liver disease","level":3,"score":0.4288032650947571},{"id":"https://openalex.org/C2778772119","wikidata":"https://www.wikidata.org/wiki/Q6058862","display_name":"Fatty liver","level":3,"score":0.4004512131214142},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.26165616512298584},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D006528","descriptor_name":"Carcinoma, Hepatocellular","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D006528","descriptor_name":"Carcinoma, Hepatocellular","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D006528","descriptor_name":"Carcinoma, Hepatocellular","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008103","descriptor_name":"Liver Cirrhosis","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D008103","descriptor_name":"Liver Cirrhosis","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D008103","descriptor_name":"Liver Cirrhosis","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D008113","descriptor_name":"Liver Neoplasms","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D008113","descriptor_name":"Liver Neoplasms","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D008113","descriptor_name":"Liver Neoplasms","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015331","descriptor_name":"Cohort Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015994","descriptor_name":"Incidence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D065626","descriptor_name":"Non-alcoholic Fatty Liver Disease","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D065626","descriptor_name":"Non-alcoholic Fatty Liver Disease","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D065626","descriptor_name":"Non-alcoholic Fatty Liver Disease","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1097/hc9.0000000000000183","doi":"https://doi.org/10.1097/hc9.0000000000000183","is_oa":true,"landing_page_url":"https://doi.org/10.1097/hc9.0000000000000183","pdf_url":null,"source":{"id":"https://openalex.org/S4210228550","display_name":"Hepatology Communications","issn_l":"2471-254X","issn":["2471-254X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-20","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Hepatology Communications","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:10319365","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10319365","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10319365/pdf/hc9-7-e00183.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Hepatol Commun","raw_type":"Text"},{"id":"pmid:37395730","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37395730","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Hepatology communications","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1097/hc9.0000000000000183","doi":"https://doi.org/10.1097/hc9.0000000000000183","is_oa":true,"landing_page_url":"https://doi.org/10.1097/hc9.0000000000000183","pdf_url":null,"source":{"id":"https://openalex.org/S4210228550","display_name":"Hepatology Communications","issn_l":"2471-254X","issn":["2471-254X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-20","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Hepatology Communications","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[{"id":"https://openalex.org/G3684789995","display_name":"A vascularized patient-derived iPSC liver acinus microphysiology system as an innovative precision medicine platform for optimizing clinical trial design for nonalcoholic fatty liver disease","funder_award_id":"UH3TR003289","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G8110843413","display_name":"Alcoholic Hepatitis Consortia: an intramural/extramural collaboration to unravel genetic determinants","funder_award_id":"U01AA026264","funder_id":"https://openalex.org/F4320337330","funder_display_name":"National Institute on Alcohol Abuse and Alcoholism"},{"id":"https://openalex.org/G8124689304","display_name":"Alcoholic Hepatitis Clinical and Translational Network Late Phase Clinical Trials and Observational Studies 7/9","funder_award_id":"U01AA026978","funder_id":"https://openalex.org/F4320337330","funder_display_name":"National Institute on Alcohol Abuse and Alcoholism"},{"id":"https://openalex.org/G9000889303","display_name":"Translational Research Training in Cancer Prevention and Control","funder_award_id":"T32CA186873","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G9000907138","display_name":"Novel Determinants for Progression of Non-Alcoholic Fatty Liver Disease to Hepatocellular Carcinoma and Other Health Outcomes","funder_award_id":"R01CA255809","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337330","display_name":"National Institute on Alcohol Abuse and Alcoholism","ror":"https://ror.org/02jzrsm59"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320337472","display_name":"National Center for Advancing Translational Sciences","ror":"https://ror.org/04pw6fb54"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4382919370.pdf","grobid_xml":"https://content.openalex.org/works/W4382919370.grobid-xml"},"referenced_works_count":34,"referenced_works":["https://openalex.org/W571628560","https://openalex.org/W1776128289","https://openalex.org/W1975567145","https://openalex.org/W2029691295","https://openalex.org/W2061326496","https://openalex.org/W2064387090","https://openalex.org/W2064890337","https://openalex.org/W2077433243","https://openalex.org/W2081324449","https://openalex.org/W2094791001","https://openalex.org/W2119190881","https://openalex.org/W2119415849","https://openalex.org/W2145954591","https://openalex.org/W2179591645","https://openalex.org/W2204688218","https://openalex.org/W2416151253","https://openalex.org/W2529917894","https://openalex.org/W2796067155","https://openalex.org/W2808368206","https://openalex.org/W2886906900","https://openalex.org/W2888259312","https://openalex.org/W2888434946","https://openalex.org/W2902537416","https://openalex.org/W2919921171","https://openalex.org/W2937538955","https://openalex.org/W2947312239","https://openalex.org/W2954348899","https://openalex.org/W2988945504","https://openalex.org/W3002581322","https://openalex.org/W3004644667","https://openalex.org/W3043014692","https://openalex.org/W3117083078","https://openalex.org/W3126086196","https://openalex.org/W3149682645"],"related_works":["https://openalex.org/W2888259312","https://openalex.org/W4389562496","https://openalex.org/W2117454090","https://openalex.org/W3207395005","https://openalex.org/W4309306328","https://openalex.org/W4282966811","https://openalex.org/W3170453251","https://openalex.org/W6946257817","https://openalex.org/W3158102012","https://openalex.org/W2541313084"],"abstract_inverted_index":{"BACKGROUND:":[0],"HCC":[1,20,44,76,96,110,133,160,185,217],"can":[2],"develop":[3,216],"in":[4,9,21,45,58,161],"the":[5,17,41,51,59,80,88,93,129,181],"absence":[6,83],"of":[7,19,43,54,63,75,84,95,159,184,244],"cirrhosis":[8,28,85,168,206,221,236],"patients":[10,22,46,101,116,131,162,178],"with":[11,23,25,47,102,117,132,163,165,191,199,203,233],"NAFLD.":[12],"We":[13,34],"aimed":[14],"to":[15,39,215],"estimate":[16],"incidence":[18,42,74,158,183,243],"NAFLD":[24,48,103,164,204,234],"and":[26,71,86,166,171,194,205,222,229],"without":[27,134,167,179,220,235],"or":[29,82],"advanced":[30,154,238],"liver":[31],"fibrosis.":[32],"METHODS:":[33],"performed":[35],"a":[36,64,241],"cohort":[37],"study":[38],"determine":[40],"identified":[49],"by":[50,79,87],"International":[52],"Classification":[53],"Diseases":[55],"9/10":[56],"codes":[57],"electronic":[60],"health":[61,66],"records":[62],"US":[65],"care":[67],"system":[68],"between":[69],"2004":[70],"2018.":[72],"The":[73,156],"was":[77,169,186],"stratified":[78],"presence":[81],"Fibrosis-4":[89],"index":[90],"(FIB-4)":[91],"at":[92],"time":[94],"diagnosis.":[97],"RESULTS:":[98],"Of":[99,128],"47,165":[100],"aged":[104],"40-89":[105],"years,":[106],"981":[107],"(2.1%)":[108],"developed":[109],"(mean":[111],"follow-up":[112],"3.4":[113],"y).":[114],"Among":[115,177],"HCC,":[118],"842":[119],"(85.8%)":[120],"had":[121,140,149],"cirrhosis,":[122,180],"while":[123],"139":[124,130],"(14.2%)":[125],"did":[126],"not.":[127],"cirrhosis-related":[135],"diagnostic":[136],"codes,":[137],"26":[138],"(2.7%)":[139],"FIB-4":[141,150,192,200,223],">2.67":[142,193],"(advanced":[143],"fibrosis":[144,239],"likely),":[145],"whereas":[146],"43":[147],"(4.4%)":[148],"<":[151],"1.30":[152],"(excluding":[153],"fibrosis).":[155],"annual":[157,182],"23.6":[170],"1.1":[172],"per":[173,188,196],"1000":[174,189,197],"person-years,":[175],"respectively.":[176],"2.8":[187],"person-years":[190,198],"0.7":[195],"<1.30.":[201],"Patients":[202,232],"were":[207],"31.8":[208],"times":[209],"(95%":[210],"CI,":[211],"23.3-43.4)":[212],"more":[213],"likely":[214],"than":[218],"those":[219],"<1.30,":[224],"after":[225],"adjustment":[226],"for":[227],"age":[228],"sex.":[230],"CONCLUSIONS:":[231],"nor":[237],"have":[240],"low":[242],"HCC.":[245]},"counts_by_year":[{"year":2026,"cited_by_count":10},{"year":2025,"cited_by_count":14},{"year":2024,"cited_by_count":13},{"year":2022,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2023-07-04T00:00:00"}