{"id":"https://openalex.org/W4382727136","doi":"https://doi.org/10.1117/1.jbo.28.6.065006","title":"Monitoring optoporated process on mammalian cells by real-time measurement of membrane resealing time","display_name":"Monitoring optoporated process on mammalian cells by real-time measurement of membrane resealing time","publication_year":2023,"publication_date":"2023-06-29","ids":{"openalex":"https://openalex.org/W4382727136","doi":"https://doi.org/10.1117/1.jbo.28.6.065006","pmid":"https://pubmed.ncbi.nlm.nih.gov/37396684","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/10308995"},"language":"en","primary_location":{"id":"doi:10.1117/1.jbo.28.6.065006","doi":"https://doi.org/10.1117/1.jbo.28.6.065006","is_oa":true,"landing_page_url":"https://doi.org/10.1117/1.jbo.28.6.065006","pdf_url":"https://www.spiedigitallibrary.org/journals/journal-of-biomedical-optics/volume-28/issue-6/065006/Monitoring-optoporated-process-on-mammalian-cells-by-real-time-measurement/10.1117/1.JBO.28.6.065006.pdf","source":{"id":"https://openalex.org/S117354312","display_name":"Journal of Biomedical Optics","issn_l":"1083-3668","issn":["1083-3668","1560-2281"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315543","host_organization_name":"SPIE","host_organization_lineage":["https://openalex.org/P4310315543"],"host_organization_lineage_names":["SPIE"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biomedical Optics","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.spiedigitallibrary.org/journals/journal-of-biomedical-optics/volume-28/issue-6/065006/Monitoring-optoporated-process-on-mammalian-cells-by-real-time-measurement/10.1117/1.JBO.28.6.065006.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5041920497","display_name":"Xiaofan Du","orcid":"https://orcid.org/0000-0002-7415-6791","observed_orcids":["https://orcid.org/0000-0002-7415-6791","https://orcid.org/0000-0002-6011-6318"]},"institutions":[{"id":"https://openalex.org/I87445476","display_name":"Xi'an Jiaotong University","ror":"https://ror.org/017zhmm22","country_code":"CN","type":"education","lineage":["https://openalex.org/I87445476"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Xiaofan Du","raw_affiliation_strings":["Xi'an Jiaotong Univ","These authors contributed equally to this work","Xi'an Jiaotong Univ. (China)","Xi\u2019an Jiaotong University, Institute of Biomedical Photonics and Sensing, School of Life Science and Technology, Key Laboratory of Biomedical Information Engineering of Ministry of Education, Xi\u2019an, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Xi'an Jiaotong Univ","institution_ids":["https://openalex.org/I87445476"]},{"raw_affiliation_string":"These authors contributed equally to this work","institution_ids":[]},{"raw_affiliation_string":"Xi'an Jiaotong Univ. (China)","institution_ids":["https://openalex.org/I87445476"]},{"raw_affiliation_string":"Xi\u2019an Jiaotong University, Institute of Biomedical Photonics and Sensing, School of Life Science and Technology, Key Laboratory of Biomedical Information Engineering of Ministry of Education, Xi\u2019an, China","institution_ids":["https://openalex.org/I87445476"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024991590","display_name":"Lei Fu","orcid":"https://orcid.org/0000-0002-5593-4180","observed_orcids":["https://orcid.org/0000-0002-5593-4180","https://orcid.org/0000-0003-3443-2453"]},"institutions":[{"id":"https://openalex.org/I87445476","display_name":"Xi'an Jiaotong University","ror":"https://ror.org/017zhmm22","country_code":"CN","type":"education","lineage":["https://openalex.org/I87445476"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Lei Fu","raw_affiliation_strings":["Xi'an Jiaotong Univ","These authors contributed equally to this work","Xi\u2019an Jiaotong University, Institute of Biomedical Photonics and Sensing, School of Life Science and Technology, Key Laboratory of Biomedical Information Engineering of Ministry of Education, Xi\u2019an, China"],"raw_orcid":"https://orcid.org/0000-0002-5593-4180","affiliations":[{"raw_affiliation_string":"Xi'an Jiaotong Univ","institution_ids":["https://openalex.org/I87445476"]},{"raw_affiliation_string":"These authors contributed equally to this work","institution_ids":[]},{"raw_affiliation_string":"Xi\u2019an Jiaotong University, Institute of Biomedical Photonics and Sensing, School of Life Science and Technology, Key Laboratory of Biomedical Information Engineering of Ministry of Education, Xi\u2019an, China","institution_ids":["https://openalex.org/I87445476"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024900044","display_name":"Zhuqu Wang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I87445476","display_name":"Xi'an Jiaotong University","ror":"https://ror.org/017zhmm22","country_code":"CN","type":"education","lineage":["https://openalex.org/I87445476"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhuqu Wang","raw_affiliation_strings":["Xi'an Jiaotong Univ","Xi\u2019an Jiaotong University, Institute of Biomedical Photonics and Sensing, School of Life Science and Technology, Key Laboratory of Biomedical Information Engineering of Ministry of Education, Xi\u2019an, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Xi'an Jiaotong Univ","institution_ids":["https://openalex.org/I87445476"]},{"raw_affiliation_string":"Xi\u2019an Jiaotong University, Institute of Biomedical Photonics and Sensing, School of Life Science and Technology, Key Laboratory of Biomedical Information Engineering of Ministry of Education, Xi\u2019an, China","institution_ids":["https://openalex.org/I87445476"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040281616","display_name":"Zhenxi Zhang","orcid":"https://orcid.org/0000-0001-7881-7270","observed_orcids":["https://orcid.org/0000-0001-7881-7270"]},"institutions":[{"id":"https://openalex.org/I87445476","display_name":"Xi'an Jiaotong University","ror":"https://ror.org/017zhmm22","country_code":"CN","type":"education","lineage":["https://openalex.org/I87445476"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhenxi Zhang","raw_affiliation_strings":["Xi'an Jiaotong Univ","Xi\u2019an Jiaotong University, Institute of Biomedical Photonics and Sensing, School of Life Science and Technology, Key Laboratory of Biomedical Information Engineering of Ministry of Education, Xi\u2019an, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Xi'an Jiaotong Univ","institution_ids":["https://openalex.org/I87445476"]},{"raw_affiliation_string":"Xi\u2019an Jiaotong University, Institute of Biomedical Photonics and Sensing, School of Life Science and Technology, Key Laboratory of Biomedical Information Engineering of Ministry of Education, Xi\u2019an, China","institution_ids":["https://openalex.org/I87445476"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029267193","display_name":"Shudong Jiang","orcid":"https://orcid.org/0000-0001-7396-7886","observed_orcids":["https://orcid.org/0000-0001-7396-7886"]},"institutions":[{"id":"https://openalex.org/I107672454","display_name":"Dartmouth College","ror":"https://ror.org/049s0rh22","country_code":"US","type":"education","lineage":["https://openalex.org/I107672454"]},{"id":"https://openalex.org/I1289422878","display_name":"Dartmouth\u2013Hitchcock Medical Center","ror":"https://ror.org/00d1dhh09","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I107672454","https://openalex.org/I1289422878","https://openalex.org/I4390039337"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shudong Jiang","raw_affiliation_strings":["Thayer School of Engineering at Dartmouth","Dartmouth College, Thayer School of Engineering, Hanover, New Hampshire, United States","Dartmouth-Hitchcock Medical Ctr. (Lebanon)"],"raw_orcid":"https://orcid.org/0000-0001-7396-7886","affiliations":[{"raw_affiliation_string":"Thayer School of Engineering at Dartmouth","institution_ids":["https://openalex.org/I107672454"]},{"raw_affiliation_string":"Dartmouth College, Thayer School of Engineering, Hanover, New Hampshire, United States","institution_ids":["https://openalex.org/I107672454"]},{"raw_affiliation_string":"Dartmouth-Hitchcock Medical Ctr. (Lebanon)","institution_ids":["https://openalex.org/I1289422878"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100378403","display_name":"Jing Wang","orcid":"https://orcid.org/0000-0001-9413-2378","observed_orcids":["https://orcid.org/0000-0001-9413-2378","https://orcid.org/0009-0009-1626-6667"]},"institutions":[{"id":"https://openalex.org/I87445476","display_name":"Xi'an Jiaotong University","ror":"https://ror.org/017zhmm22","country_code":"CN","type":"education","lineage":["https://openalex.org/I87445476"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Jing Wang","raw_affiliation_strings":["Xi'an Jiaotong Univ","These authors contributed equally to this work","Xi\u2019an Jiaotong University, Institute of Biomedical Photonics and Sensing, School of Life Science and Technology, Key Laboratory of Biomedical Information Engineering of Ministry of Education, Xi\u2019an, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Xi'an Jiaotong Univ","institution_ids":["https://openalex.org/I87445476"]},{"raw_affiliation_string":"These authors contributed equally to this work","institution_ids":[]},{"raw_affiliation_string":"Xi\u2019an Jiaotong University, Institute of Biomedical Photonics and Sensing, School of Life Science and Technology, Key Laboratory of Biomedical Information Engineering of Ministry of Education, Xi\u2019an, China","institution_ids":["https://openalex.org/I87445476"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5040679141","display_name":"Cuiping Yao","orcid":"https://orcid.org/0000-0002-7110-0696","observed_orcids":["https://orcid.org/0000-0002-7110-0696"]},"institutions":[{"id":"https://openalex.org/I87445476","display_name":"Xi'an Jiaotong University","ror":"https://ror.org/017zhmm22","country_code":"CN","type":"education","lineage":["https://openalex.org/I87445476"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Cuiping Yao","raw_affiliation_strings":["Xi'an Jiaotong Univ","These authors contributed equally to this work","Xi\u2019an Jiaotong University, Institute of Biomedical Photonics and Sensing, School of Life Science and Technology, Key Laboratory of Biomedical Information Engineering of Ministry of Education, Xi\u2019an, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Xi'an Jiaotong Univ","institution_ids":["https://openalex.org/I87445476"]},{"raw_affiliation_string":"These authors contributed equally to this work","institution_ids":[]},{"raw_affiliation_string":"Xi\u2019an Jiaotong University, Institute of Biomedical Photonics and Sensing, School of Life Science and Technology, Key Laboratory of Biomedical Information Engineering of Ministry of Education, Xi\u2019an, China","institution_ids":["https://openalex.org/I87445476"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5024991590","https://openalex.org/A5040679141","https://openalex.org/A5041920497","https://openalex.org/A5100378403"],"corresponding_institution_ids":["https://openalex.org/I87445476"],"apc_list":{"value":1675,"currency":"USD","value_usd":1675},"apc_paid":{"value":1675,"currency":"USD","value_usd":1675},"fwci":1.2833,"has_fulltext":true,"cited_by_count":7,"citation_normalized_percentile":{"value":0.80286773,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":98},"biblio":{"volume":"28","issue":"06","first_page":"1","last_page":"13"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10957","display_name":"Photodynamic Therapy Research Studies","score":0.7407000064849854,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10957","display_name":"Photodynamic Therapy Research Studies","score":0.7407000064849854,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11455","display_name":"Microbial Inactivation Methods","score":0.09589999914169312,"subfield":{"id":"https://openalex.org/subfields/1305","display_name":"Biotechnology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10725","display_name":"RNA Interference and Gene Delivery","score":0.04360000044107437,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/optoporation","display_name":"optoporation","score":0.8289999961853027},{"id":"https://openalex.org/keywords/photoporation","display_name":"photoporation","score":0.8709999918937683},{"id":"https://openalex.org/keywords/gold-nanoparticles","display_name":"gold nanoparticles","score":0.9380000233650208},{"id":"https://openalex.org/keywords/voltage-sensitive-dyes","display_name":"voltage-sensitive dyes","score":0.6980000138282776},{"id":"https://openalex.org/keywords/membrane-potential","display_name":"membrane potential","score":0.6370000243186951},{"id":"https://openalex.org/keywords/drug-delivery","display_name":"drug delivery","score":0.5339999794960022},{"id":"https://openalex.org/keywords/gene-delivery","display_name":"gene delivery","score":0.9890000224113464},{"id":"https://openalex.org/keywords/intracellular-diffusion","display_name":"intracellular diffusion","score":0.5929999947547913},{"id":"https://openalex.org/keywords/loading-efficiency","display_name":"loading efficiency","score":0.6150000095367432},{"id":"https://openalex.org/keywords/hela-cells","display_name":"HeLa cells","score":0.7900000214576721},{"id":"https://openalex.org/keywords/monte-carlo-simulation","display_name":"Monte Carlo simulation","score":0.6240000128746033},{"id":"https://openalex.org/keywords/fluorescence-imaging","display_name":"fluorescence imaging","score":0.36399999260902405}],"concepts":[{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.6736759543418884},{"id":"https://openalex.org/C22078206","wikidata":"https://www.wikidata.org/wiki/Q1418023","display_name":"Fluence","level":3,"score":0.5710093975067139},{"id":"https://openalex.org/C155672457","wikidata":"https://www.wikidata.org/wiki/Q61231","display_name":"Nanoparticle","level":2,"score":0.44406160712242126},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.41772350668907166},{"id":"https://openalex.org/C520434653","wikidata":"https://www.wikidata.org/wiki/Q38867","display_name":"Laser","level":2,"score":0.3668256402015686},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.3382822573184967},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.3051328659057617},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.2787255346775055},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002462","descriptor_name":"Cell Membrane","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004364","descriptor_name":"Pharmaceutical Preparations","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006046","descriptor_name":"Gold","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006367","descriptor_name":"HeLa Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008322","descriptor_name":"Mammals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053768","descriptor_name":"Metal Nanoparticles","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1117/1.jbo.28.6.065006","doi":"https://doi.org/10.1117/1.jbo.28.6.065006","is_oa":true,"landing_page_url":"https://doi.org/10.1117/1.jbo.28.6.065006","pdf_url":"https://www.spiedigitallibrary.org/journals/journal-of-biomedical-optics/volume-28/issue-6/065006/Monitoring-optoporated-process-on-mammalian-cells-by-real-time-measurement/10.1117/1.JBO.28.6.065006.pdf","source":{"id":"https://openalex.org/S117354312","display_name":"Journal of Biomedical Optics","issn_l":"1083-3668","issn":["1083-3668","1560-2281"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315543","host_organization_name":"SPIE","host_organization_lineage":["https://openalex.org/P4310315543"],"host_organization_lineage_names":["SPIE"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biomedical Optics","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:10308995","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10308995","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10308995/pdf/JBO-028-065006.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Biomed Opt","raw_type":"Text"},{"id":"pmid:37396684","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37396684","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of biomedical optics","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1117/1.jbo.28.6.065006","doi":"https://doi.org/10.1117/1.jbo.28.6.065006","is_oa":true,"landing_page_url":"https://doi.org/10.1117/1.jbo.28.6.065006","pdf_url":"https://www.spiedigitallibrary.org/journals/journal-of-biomedical-optics/volume-28/issue-6/065006/Monitoring-optoporated-process-on-mammalian-cells-by-real-time-measurement/10.1117/1.JBO.28.6.065006.pdf","source":{"id":"https://openalex.org/S117354312","display_name":"Journal of Biomedical Optics","issn_l":"1083-3668","issn":["1083-3668","1560-2281"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315543","host_organization_name":"SPIE","host_organization_lineage":["https://openalex.org/P4310315543"],"host_organization_lineage_names":["SPIE"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biomedical Optics","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G2677882634","display_name":null,"funder_award_id":"2022ZDLSF04-09","funder_id":"https://openalex.org/F4320336350","funder_display_name":"Key Research and Development Projects of Shaanxi Province"},{"id":"https://openalex.org/G4134325585","display_name":null,"funder_award_id":"62005210","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G6901514510","display_name":null,"funder_award_id":"82272048","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G7353716728","display_name":null,"funder_award_id":"62175198","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320336350","display_name":"Key Research and Development Projects of Shaanxi Province","ror":null}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4382727136.pdf","grobid_xml":"https://content.openalex.org/works/W4382727136.grobid-xml"},"referenced_works_count":40,"referenced_works":["https://openalex.org/W1182310137","https://openalex.org/W1847673137","https://openalex.org/W1962226522","https://openalex.org/W1963580598","https://openalex.org/W1969899774","https://openalex.org/W1975643595","https://openalex.org/W2004330004","https://openalex.org/W2033790066","https://openalex.org/W2062863320","https://openalex.org/W2072792798","https://openalex.org/W2080496437","https://openalex.org/W2104430478","https://openalex.org/W2111837159","https://openalex.org/W2120908183","https://openalex.org/W2128683755","https://openalex.org/W2128705181","https://openalex.org/W2133870746","https://openalex.org/W2138392728","https://openalex.org/W2157703710","https://openalex.org/W2313075323","https://openalex.org/W2320221937","https://openalex.org/W2473033301","https://openalex.org/W2574124881","https://openalex.org/W2744185888","https://openalex.org/W2875025015","https://openalex.org/W2886088980","https://openalex.org/W2890777036","https://openalex.org/W2895261006","https://openalex.org/W2895572419","https://openalex.org/W2898384787","https://openalex.org/W2900640966","https://openalex.org/W2905252116","https://openalex.org/W2922709849","https://openalex.org/W2959307148","https://openalex.org/W2970981456","https://openalex.org/W2998307242","https://openalex.org/W3013635432","https://openalex.org/W3140183458","https://openalex.org/W3205007261","https://openalex.org/W4224255841"],"related_works":["https://openalex.org/W1963580598","https://openalex.org/W2015404555","https://openalex.org/W998681907","https://openalex.org/W2080496437","https://openalex.org/W2104430478","https://openalex.org/W4244207260","https://openalex.org/W2074228227","https://openalex.org/W2041662303","https://openalex.org/W2283101411","https://openalex.org/W1996569510"],"abstract_inverted_index":{"Significance:":[0],"Resealing":[1],"time":[2,32,56,81,139,185],"based":[3,109],"loading":[4,193],"efficiency":[5,155,194],"of":[6,33,54,57,129,142,156,186,199],"optoporation":[7],"is":[8,133],"the":[9,28,34,58,70,79,85,90,106,118,137,160,192,197],"key":[10],"parameter":[11],"for":[12,189],"drug":[13],"or":[14],"gene":[15],"delivery.":[16],"This":[17,131],"work":[18],"describes":[19],"a":[20,42,51,123],"comparatively":[21],"simple":[22],"optical":[23,46],"approach":[24,101],"to":[25,68,89,181],"directly":[26,182],"measure":[27,183],"cell":[29,74],"membrane":[30,43],"resealing":[31,55,80,138,184],"gold":[35,71],"nanoparticle":[36,72],"mediated":[37],"photoporation.":[38],"Aim:":[39],"To":[40],"establish":[41],"potential":[44],"detection":[45],"system,":[47],"which":[48],"can":[49,178],"provide":[50],"direct":[52],"measurement":[53],"optoporated":[59,187],"cells.":[60],"Approach:":[61],"Voltage":[62],"sensitive":[63],"dye":[64],"has":[65,102],"been":[66,103],"used":[67,180],"label":[69],"covered":[73],"before":[75,95],"laser":[76,98],"activation":[77],"and":[78,96,113,117],"was":[82],"estimated":[83],"from":[84,122],"voltage":[86],"change":[87,94],"due":[88],"fluorescence":[91],"light":[92],"intensity":[93],"after":[97],"activation.":[99],"The":[100,152,174],"validated":[104],"by":[105,148],"simulated":[107],"data":[108,120],"on":[110,166,195],"diffusion":[111,167],"model":[112],"Monte":[114],"Carlo":[115],"simulation":[116],"experimental":[119],"obtained":[121],"flow":[124],"cytometry":[125],"analysis.":[126],"Results:":[127],")":[128],"0.9938.":[130],"result":[132],"in":[134],"agreement":[135],"with":[136],"(1-2":[140],"min)":[141],"photothermal":[143],"porated":[144],"Hela":[145],"cells":[146,188],"measured":[147],"electrical":[149],"impedance":[150],"method.":[151],"intracellular":[153],"delivery":[154],"extracellular":[157],"macromolecular":[158],"under":[159],"same":[161],"irradiation":[162],"fluence":[163],"depends":[164],"mainly":[165],"velocity":[168],"rather":[169],"than":[170],"pore":[171],"size.":[172],"Conclusion:":[173],"method":[175],"described":[176],"here":[177],"be":[179],"accurately":[190],"estimating":[191],"discovering":[196],"mechanism":[198],"optoporation.":[200]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":5}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2023-07-01T00:00:00"}
