{"id":"https://openalex.org/W4382677472","doi":"https://doi.org/10.1016/j.jstrokecerebrovasdis.2023.107240","title":"Improved cardiorespiratory fitness is associated with lower incident ischemic stroke risk: Henry Ford FIT project","display_name":"Improved cardiorespiratory fitness is associated with lower incident ischemic stroke risk: Henry Ford FIT project","publication_year":2023,"publication_date":"2023-06-30","ids":{"openalex":"https://openalex.org/W4382677472","doi":"https://doi.org/10.1016/j.jstrokecerebrovasdis.2023.107240","pmid":"https://pubmed.ncbi.nlm.nih.gov/37393688"},"language":"en","primary_location":{"id":"doi:10.1016/j.jstrokecerebrovasdis.2023.107240","doi":"https://doi.org/10.1016/j.jstrokecerebrovasdis.2023.107240","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jstrokecerebrovasdis.2023.107240","pdf_url":null,"source":{"id":"https://openalex.org/S4210174059","display_name":"Journal of Stroke and Cerebrovascular Diseases","issn_l":"1052-3057","issn":["1052-3057","1532-8511"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Stroke and Cerebrovascular Diseases","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5079680570","display_name":"Jonathan K. Ehrman","orcid":"https://orcid.org/0000-0003-0717-0670","observed_orcids":["https://orcid.org/0000-0003-0717-0670"]},"institutions":[{"id":"https://openalex.org/I154057602","display_name":"Henry Ford Health","ror":"https://ror.org/02kwnkm68","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I154057602"]},{"id":"https://openalex.org/I2803043754","display_name":"Henry Ford Hospital","ror":"https://ror.org/0193sb042","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I154057602","https://openalex.org/I2803043754"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Jonathan K. Ehrman","raw_affiliation_strings":["Division of Cardiovascular Medicine, Henry Ford Hospital, Detroit, MI, USA. Electronic address: Jehrman1@hfhs.org","Division of Cardiovascular Medicine, Henry Ford Hospital, Detroit, MI, USA"],"raw_orcid":"https://orcid.org/0000-0003-0717-0670","affiliations":[{"raw_affiliation_string":"Division of Cardiovascular Medicine, Henry Ford Hospital, Detroit, MI, USA. Electronic address: Jehrman1@hfhs.org","institution_ids":["https://openalex.org/I154057602","https://openalex.org/I2803043754"]},{"raw_affiliation_string":"Division of Cardiovascular Medicine, Henry Ford Hospital, Detroit, MI, USA","institution_ids":["https://openalex.org/I154057602","https://openalex.org/I2803043754"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065605818","display_name":"Steven J. Keteyian","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154057602","display_name":"Henry Ford Health","ror":"https://ror.org/02kwnkm68","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I154057602"]},{"id":"https://openalex.org/I2803043754","display_name":"Henry Ford Hospital","ror":"https://ror.org/0193sb042","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I154057602","https://openalex.org/I2803043754"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Steven J. Keteyian","raw_affiliation_strings":["Division of Cardiovascular Medicine, Henry Ford Hospital, Detroit, MI, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiovascular Medicine, Henry Ford Hospital, Detroit, MI, USA","institution_ids":["https://openalex.org/I154057602","https://openalex.org/I2803043754"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075996094","display_name":"Michelle C. Johansen","orcid":"https://orcid.org/0000-0003-0393-3589","observed_orcids":["https://orcid.org/0000-0003-0393-3589"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I2799853436","display_name":"Johns Hopkins Medicine","ror":"https://ror.org/037zgn354","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michelle C. Johansen","raw_affiliation_strings":["Cerebrovascular Division, Department of Neurology, The Johns Hopkins School of Medicine, Baltimore, MD, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cerebrovascular Division, Department of Neurology, The Johns Hopkins School of Medicine, Baltimore, MD, USA","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I2799853436"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008531984","display_name":"Michael Joseph Blaha","orcid":"https://orcid.org/0000-0001-5138-9683","observed_orcids":["https://orcid.org/0000-0001-5138-9683"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I2799853436","display_name":"Johns Hopkins Medicine","ror":"https://ror.org/037zgn354","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael J. Blaha","raw_affiliation_strings":["Ciccarone Center for the Prevention of Heart Disease, Johns Hopkins Medicine, Lutherville, MD, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ciccarone Center for the Prevention of Heart Disease, Johns Hopkins Medicine, Lutherville, MD, USA","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I2799853436"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023253601","display_name":"Mouaz Husayn Al-Mallah","orcid":"https://orcid.org/0000-0003-2348-0484","observed_orcids":["https://orcid.org/0000-0003-2348-0484"]},"institutions":[{"id":"https://openalex.org/I1295876152","display_name":"Houston Methodist","ror":"https://ror.org/027zt9171","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1295876152"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mouaz H. Al-Mallah","raw_affiliation_strings":["Houston Methodist DeBakey Heart & Vascular Center, Houston, TX, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Houston Methodist DeBakey Heart & Vascular Center, Houston, TX, USA","institution_ids":["https://openalex.org/I1295876152"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5022578470","display_name":"Clinton A. Brawner","orcid":"https://orcid.org/0000-0002-1705-6620","observed_orcids":["https://orcid.org/0000-0002-1705-6620"]},"institutions":[{"id":"https://openalex.org/I154057602","display_name":"Henry Ford Health","ror":"https://ror.org/02kwnkm68","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I154057602"]},{"id":"https://openalex.org/I2803043754","display_name":"Henry Ford Hospital","ror":"https://ror.org/0193sb042","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I154057602","https://openalex.org/I2803043754"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Clinton A. Brawner","raw_affiliation_strings":["Division of Cardiovascular Medicine, Henry Ford Hospital, Detroit, MI, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiovascular Medicine, Henry Ford Hospital, Detroit, MI, USA","institution_ids":["https://openalex.org/I154057602","https://openalex.org/I2803043754"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5079680570"],"corresponding_institution_ids":["https://openalex.org/I154057602","https://openalex.org/I2803043754"],"apc_list":{"value":3000,"currency":"USD","value_usd":3000},"apc_paid":null,"fwci":3.9501,"has_fulltext":false,"cited_by_count":13,"citation_normalized_percentile":{"value":0.92859259,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":93,"max":98},"biblio":{"volume":"32","issue":"8","first_page":"107240","last_page":"107240"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11209","display_name":"Cardiovascular and exercise physiology","score":0.5565999746322632,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11209","display_name":"Cardiovascular and exercise physiology","score":0.5565999746322632,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10352","display_name":"Physical Activity and Health","score":0.42160001397132874,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10227","display_name":"Acute Ischemic Stroke Management","score":0.009100000374019146,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cardiorespiratory-fitness","display_name":"cardiorespiratory fitness","score":0.9990000128746033},{"id":"https://openalex.org/keywords/ischemic-stroke","display_name":"ischemic stroke","score":0.9789999723434448},{"id":"https://openalex.org/keywords/exercise-testing","display_name":"exercise testing","score":0.7400000095367432},{"id":"https://openalex.org/keywords/mets","display_name":"METS","score":0.7480000257492065},{"id":"https://openalex.org/keywords/stroke-prevention","display_name":"stroke prevention","score":0.5569999814033508},{"id":"https://openalex.org/keywords/exercise-intervention","display_name":"exercise intervention","score":0.3970000147819519},{"id":"https://openalex.org/keywords/vascular-risk","display_name":"vascular risk","score":0.7990000247955322}],"concepts":[{"id":"https://openalex.org/C117437137","wikidata":"https://www.wikidata.org/wiki/Q5038720","display_name":"Cardiorespiratory fitness","level":2,"score":0.8948829174041748},{"id":"https://openalex.org/C2780645631","wikidata":"https://www.wikidata.org/wiki/Q671554","display_name":"Stroke (engine)","level":2,"score":0.5025882720947266},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4675648808479309},{"id":"https://openalex.org/C3020199598","wikidata":"https://www.wikidata.org/wiki/Q12202","display_name":"Ischemic stroke","level":3,"score":0.43797796964645386},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.34984657168388367},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.348061740398407},{"id":"https://openalex.org/C99508421","wikidata":"https://www.wikidata.org/wiki/Q2678675","display_name":"Physical medicine and rehabilitation","level":1,"score":0.34676313400268555},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.1710035800933838},{"id":"https://openalex.org/C541997718","wikidata":"https://www.wikidata.org/wiki/Q188151","display_name":"Ischemia","level":2,"score":0.08148521184921265},{"id":"https://openalex.org/C78519656","wikidata":"https://www.wikidata.org/wiki/Q101333","display_name":"Mechanical engineering","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000072599","descriptor_name":"Cardiorespiratory Fitness","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000083242","descriptor_name":"Ischemic Stroke","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005080","descriptor_name":"Exercise Test","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010809","descriptor_name":"Physical Fitness","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.jstrokecerebrovasdis.2023.107240","doi":"https://doi.org/10.1016/j.jstrokecerebrovasdis.2023.107240","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jstrokecerebrovasdis.2023.107240","pdf_url":null,"source":{"id":"https://openalex.org/S4210174059","display_name":"Journal of Stroke and Cerebrovascular Diseases","issn_l":"1052-3057","issn":["1052-3057","1532-8511"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Stroke and Cerebrovascular Diseases","raw_type":"journal-article"},{"id":"pmid:37393688","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37393688","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association","raw_type":"Observational Study"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":27,"referenced_works":["https://openalex.org/W1984207902","https://openalex.org/W1988364609","https://openalex.org/W2006315159","https://openalex.org/W2038981426","https://openalex.org/W2071099424","https://openalex.org/W2096205265","https://openalex.org/W2107258674","https://openalex.org/W2116623234","https://openalex.org/W2130661160","https://openalex.org/W2139219244","https://openalex.org/W2145173489","https://openalex.org/W2158248411","https://openalex.org/W2159012621","https://openalex.org/W2345689257","https://openalex.org/W2585605401","https://openalex.org/W2586574386","https://openalex.org/W2598024881","https://openalex.org/W2905429437","https://openalex.org/W3039103932","https://openalex.org/W3119924594","https://openalex.org/W3126240756","https://openalex.org/W3150386126","https://openalex.org/W3197944066","https://openalex.org/W4210242902","https://openalex.org/W4229014963","https://openalex.org/W4297157268","https://openalex.org/W4320300836"],"related_works":["https://openalex.org/W3039103932","https://openalex.org/W4387461252","https://openalex.org/W2987397256","https://openalex.org/W4399386157","https://openalex.org/W4379797650","https://openalex.org/W2914448149","https://openalex.org/W4407805896","https://openalex.org/W2794728575","https://openalex.org/W2617008763","https://openalex.org/W2918318742"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2023-07-01T00:00:00"}