{"id":"https://openalex.org/W4382289149","doi":"https://doi.org/10.2174/9789815123043123010009","title":"Activity Methods for Polycystic Ovary Syndrome","display_name":"Activity Methods for Polycystic Ovary Syndrome","publication_year":2023,"publication_date":"2023-06-25","ids":{"openalex":"https://openalex.org/W4382289149","doi":"https://doi.org/10.2174/9789815123043123010009"},"language":"en","primary_location":{"id":"doi:10.2174/9789815123043123010009","doi":"https://doi.org/10.2174/9789815123043123010009","is_oa":false,"landing_page_url":"http://dx.doi.org/10.2174/9789815123043123010009","pdf_url":null,"source":{"id":"https://openalex.org/S4306462908","display_name":"BENTHAM SCIENCE PUBLISHERS eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Methods for Preclinical Evaluation of Bioactive Natural Products","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W4382284786","display_name":"Methods for Preclinical Evaluation of Bioactive Natural Products"},"type":"book-chapter","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5076736413","display_name":"M\u00fcr\u015fide Ay\u015fe Demirel","orcid":"https://orcid.org/0000-0002-7082-8976","observed_orcids":["https://orcid.org/0000-0002-7082-8976"]},"institutions":[{"id":"https://openalex.org/I95634034","display_name":"Gazi University","ror":"https://ror.org/054xkpr46","country_code":"TR","type":"education","lineage":["https://openalex.org/I95634034"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Murside Ayse Demirel","raw_affiliation_strings":["Department of Pharmaceutical Basic Sciences, Faculty of Pharmacy, Gazi University, Etiler, Ankara, T\u00fcrkiye"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmaceutical Basic Sciences, Faculty of Pharmacy, Gazi University, Etiler, Ankara, T\u00fcrkiye","institution_ids":["https://openalex.org/I95634034"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071459453","display_name":"Kevser Taban Ak\u00e7a","orcid":"https://orcid.org/0000-0001-8620-6402","observed_orcids":["https://orcid.org/0000-0001-8620-6402"]},"institutions":[{"id":"https://openalex.org/I95634034","display_name":"Gazi University","ror":"https://ror.org/054xkpr46","country_code":"TR","type":"education","lineage":["https://openalex.org/I95634034"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Kevser Taban Ak\u00e7a","raw_affiliation_strings":["Department of Pharmacognosy, Faculty of Pharmacy, Gazi University, Etiler, Ankara, T\u00fcrkiye"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacognosy, Faculty of Pharmacy, Gazi University, Etiler, Ankara, T\u00fcrkiye","institution_ids":["https://openalex.org/I95634034"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048604040","display_name":"S\u00fcmeyra \u00c7etinkaya","orcid":"https://orcid.org/0000-0002-5811-8832","observed_orcids":["https://orcid.org/0000-0002-5811-8832"]},"institutions":[{"id":"https://openalex.org/I4405262973","display_name":"Ministry of Agriculture and Forestry","ror":"https://ror.org/00tmg5839","country_code":"TR","type":"government","lineage":["https://openalex.org/I4405262973"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"S\u00fcmeyra \u00c7etinkaya","raw_affiliation_strings":["Biotechnology Research Center of Ministry of Agriculture and Forestry, 06330, Yenimahalle, Ankara, T\u00fcrkiye"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biotechnology Research Center of Ministry of Agriculture and Forestry, 06330, Yenimahalle, Ankara, T\u00fcrkiye","institution_ids":["https://openalex.org/I4405262973"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5063989693","display_name":"Ipek Pe\u015fin S\u00fcntar","orcid":"https://orcid.org/0000-0003-4201-1325","observed_orcids":["https://orcid.org/0000-0003-4201-1325"]},"institutions":[{"id":"https://openalex.org/I95634034","display_name":"Gazi University","ror":"https://ror.org/054xkpr46","country_code":"TR","type":"education","lineage":["https://openalex.org/I95634034"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Ipek S\u00fcntar","raw_affiliation_strings":["Department of Pharmacognosy, Faculty of Pharmacy, Gazi University, Etiler, Ankara, T\u00fcrkiye"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacognosy, Faculty of Pharmacy, Gazi University, Etiler, Ankara, T\u00fcrkiye","institution_ids":["https://openalex.org/I95634034"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"200","last_page":"228"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10390","display_name":"Ovarian function and disorders","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10390","display_name":"Ovarian function and disorders","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14521","display_name":"Medicinal Plant Research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10364","display_name":"Reproductive Biology and Fertility","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/polycystic-ovary-syndrome","display_name":"polycystic ovary syndrome","score":1.0},{"id":"https://openalex.org/keywords/plant-extracts","display_name":"plant extracts","score":0.8199999928474426},{"id":"https://openalex.org/keywords/phytochemicals","display_name":"phytochemicals","score":0.9980000257492065},{"id":"https://openalex.org/keywords/plant-based-treatment","display_name":"plant-based treatment","score":0.7839999794960022},{"id":"https://openalex.org/keywords/pcos-pathophysiology","display_name":"PCOS pathophysiology","score":0.7839999794960022},{"id":"https://openalex.org/keywords/hyperinsulinemia","display_name":"hyperinsulinemia","score":0.8080000281333923},{"id":"https://openalex.org/keywords/hyperandrogenism","display_name":"hyperandrogenism","score":0.9929999709129333},{"id":"https://openalex.org/keywords/systemic-inflammation","display_name":"systemic inflammation","score":0.7020000219345093}],"concepts":[{"id":"https://openalex.org/C3018442814","wikidata":"https://www.wikidata.org/wiki/Q500816","display_name":"Polycystic ovary","level":4,"score":0.9698325395584106},{"id":"https://openalex.org/C2780186808","wikidata":"https://www.wikidata.org/wiki/Q10529545","display_name":"Hyperandrogenism","level":5,"score":0.9097224473953247},{"id":"https://openalex.org/C2780988686","wikidata":"https://www.wikidata.org/wiki/Q14375936","display_name":"Hyperinsulinemia","level":4,"score":0.7582192420959473},{"id":"https://openalex.org/C2778324911","wikidata":"https://www.wikidata.org/wiki/Q9631","display_name":"Ovary","level":2,"score":0.5196974873542786},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4813714623451233},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.47314393520355225},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.47074609994888306},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.45502927899360657},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.35505300760269165},{"id":"https://openalex.org/C2777391703","wikidata":"https://www.wikidata.org/wiki/Q1053470","display_name":"Insulin resistance","level":3,"score":0.13183489441871643},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.10406488180160522}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.2174/9789815123043123010009","doi":"https://doi.org/10.2174/9789815123043123010009","is_oa":false,"landing_page_url":"http://dx.doi.org/10.2174/9789815123043123010009","pdf_url":null,"source":{"id":"https://openalex.org/S4306462908","display_name":"BENTHAM SCIENCE PUBLISHERS eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Methods for Preclinical Evaluation of Bioactive Natural Products","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9476000070571899,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":87,"referenced_works":["https://openalex.org/W1561098029","https://openalex.org/W1925133947","https://openalex.org/W1970586482","https://openalex.org/W1972677934","https://openalex.org/W1977302926","https://openalex.org/W1990054947","https://openalex.org/W2004724302","https://openalex.org/W2037342776","https://openalex.org/W2043550460","https://openalex.org/W2077717013","https://openalex.org/W2078104256","https://openalex.org/W2084300141","https://openalex.org/W2087004090","https://openalex.org/W2087417442","https://openalex.org/W2088482185","https://openalex.org/W2089082910","https://openalex.org/W2095002885","https://openalex.org/W2098825239","https://openalex.org/W2104549611","https://openalex.org/W2133118867","https://openalex.org/W2148399174","https://openalex.org/W2163699164","https://openalex.org/W2180887210","https://openalex.org/W2265398364","https://openalex.org/W2282353418","https://openalex.org/W2286230419","https://openalex.org/W2299308265","https://openalex.org/W2470829143","https://openalex.org/W2497635877","https://openalex.org/W2503951330","https://openalex.org/W2523733243","https://openalex.org/W2547748974","https://openalex.org/W2559894203","https://openalex.org/W2560430754","https://openalex.org/W2606086333","https://openalex.org/W2615666262","https://openalex.org/W2623220743","https://openalex.org/W2735516365","https://openalex.org/W2778921065","https://openalex.org/W2780093861","https://openalex.org/W2782656910","https://openalex.org/W2792351428","https://openalex.org/W2800251215","https://openalex.org/W2800354086","https://openalex.org/W2811423579","https://openalex.org/W2873868291","https://openalex.org/W2884700479","https://openalex.org/W2897678356","https://openalex.org/W2907508697","https://openalex.org/W2907764597","https://openalex.org/W2910919923","https://openalex.org/W2911053275","https://openalex.org/W2921161416","https://openalex.org/W2941727047","https://openalex.org/W2947541011","https://openalex.org/W2949336662","https://openalex.org/W2958156059","https://openalex.org/W2972258394","https://openalex.org/W2982343068","https://openalex.org/W2989789584","https://openalex.org/W2991620808","https://openalex.org/W2992296851","https://openalex.org/W2997089400","https://openalex.org/W3000023256","https://openalex.org/W3001783841","https://openalex.org/W3012576903","https://openalex.org/W3019427062","https://openalex.org/W3081543501","https://openalex.org/W3086101576","https://openalex.org/W3092292178","https://openalex.org/W3096236959","https://openalex.org/W3109739180","https://openalex.org/W3116976053","https://openalex.org/W3118554437","https://openalex.org/W3126322081","https://openalex.org/W3126507070","https://openalex.org/W3139477823","https://openalex.org/W3141366213","https://openalex.org/W3149662961","https://openalex.org/W3166481595","https://openalex.org/W3186322568","https://openalex.org/W3198390820","https://openalex.org/W3204818213","https://openalex.org/W3205223132","https://openalex.org/W3209823613","https://openalex.org/W3214465556","https://openalex.org/W3215317959"],"related_works":["https://openalex.org/W4394898571","https://openalex.org/W4384035832","https://openalex.org/W4412546224","https://openalex.org/W2802210773","https://openalex.org/W4387520810","https://openalex.org/W1534669251","https://openalex.org/W4396814399","https://openalex.org/W4412368873","https://openalex.org/W4323662591","https://openalex.org/W4403846837"],"abstract_inverted_index":{"Polycystic":[0],"ovary":[1],"syndrome":[2],"(PCOS)":[3],"is":[4],"one":[5],"of":[6,14,22,52,62],"the":[7,50,60],"most":[8],"common":[9],"gynecological":[10],"disorders":[11],"among":[12],"women":[13],"reproductive":[15],"age.":[16],"The":[17],"secretion":[18],"rate":[19],"and":[20,24,38,47,64,71,95],"metabolism":[21],"estrogens":[23],"androgens":[25],"are":[26,76,98],"disrupted":[27],"in":[28,83,100],"patients":[29],"with":[30],"PCOS.":[31],"Patients":[32],"have":[33,44],"systemic":[34],"inflammation,":[35],"hyperinsulinemia,":[36],"hyperandrogenism,":[37],"polycystic":[39],"ovaries.":[40],"Several":[41],"experimental":[42],"models":[43],"been":[45],"developed":[46],"studied":[48],"for":[49],"investigation":[51],"this":[53,86],"disease.":[54],"These":[55],"studies":[56],"aim":[57],"to":[58,78],"explore":[59],"pathophysiology":[61],"PCOS":[63,82],"new":[65],"treatment":[66,93],"approaches.":[67],"Some":[68],"plant":[69],"extracts":[70],"phytochemicals":[72],"obtained":[73],"from":[74],"them":[75],"shown":[77],"be":[79],"effective":[80],"against":[81],"literature.":[84],"In":[85],"chapter,":[87],"general":[88],"information":[89],"about":[90],"PCOS,":[91],"plant-based":[92],"approaches,":[94],"activity":[96],"methods":[97],"explained":[99],"detail.":[101]},"counts_by_year":[],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2023-06-28T00:00:00"}