{"id":"https://openalex.org/W4382011844","doi":"https://doi.org/10.1002/j.2040-4603.2023.tb00272.x","title":"Serotonergic Control of Gastrointestinal Development, Motility, and Inflammation","display_name":"Serotonergic Control of Gastrointestinal Development, Motility, and Inflammation","publication_year":2023,"publication_date":"2023-06-26","ids":{"openalex":"https://openalex.org/W4382011844","doi":"https://doi.org/10.1002/j.2040-4603.2023.tb00272.x","pmid":"https://pubmed.ncbi.nlm.nih.gov/37358510","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/10373054"},"language":"en","primary_location":{"id":"doi:10.1002/j.2040-4603.2023.tb00272.x","doi":"https://doi.org/10.1002/j.2040-4603.2023.tb00272.x","is_oa":false,"landing_page_url":"https://doi.org/10.1002/j.2040-4603.2023.tb00272.x","pdf_url":null,"source":{"id":"https://openalex.org/S18747983","display_name":"Comprehensive physiology","issn_l":"2040-4603","issn":["2040-4603"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","norway-1","poland-200","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Comprehensive Physiology","raw_type":"journal-article"},"volume":{"id":"https://openalex.org/W2787983500","display_name":"Comprehensive Physiology"},"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/cphy.c220024","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5071821499","display_name":"Sarah A. Najjar","orcid":"https://orcid.org/0000-0003-1959-8658","observed_orcids":["https://orcid.org/0000-0003-1959-8658"]},"institutions":[{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sarah A. Najjar","raw_affiliation_strings":["Department of Molecular Pathobiology, NYU College of Dentistry, New York, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Pathobiology, NYU College of Dentistry, New York, New York, USA","institution_ids":["https://openalex.org/I57206974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067760423","display_name":"Lin Yung Hung","orcid":"https://orcid.org/0000-0002-5670-3907","observed_orcids":["https://orcid.org/0000-0002-5670-3907"]},"institutions":[{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lin Y. Hung","raw_affiliation_strings":["Department of Molecular Pathobiology, NYU College of Dentistry, New York, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Pathobiology, NYU College of Dentistry, New York, New York, USA","institution_ids":["https://openalex.org/I57206974"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5040278204","display_name":"Kara Gross Margolis","orcid":"https://orcid.org/0000-0002-5795-0758","observed_orcids":["https://orcid.org/0000-0002-5795-0758"]},"institutions":[{"id":"https://openalex.org/I4210086933","display_name":"NYU Langone Health","ror":"https://ror.org/005dvqh91","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210086933"]},{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Kara Gross Margolis","raw_affiliation_strings":["Department of Molecular Pathobiology, NYU College of Dentistry, New York, New York, USA","Department of Pediatrics, NYU Langone Medical Center, New York, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Pathobiology, NYU College of Dentistry, New York, New York, USA","institution_ids":["https://openalex.org/I57206974"]},{"raw_affiliation_string":"Department of Pediatrics, NYU Langone Medical Center, New York, New York, USA","institution_ids":["https://openalex.org/I4210086933"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5040278204"],"corresponding_institution_ids":["https://openalex.org/I4210086933","https://openalex.org/I57206974"],"apc_list":null,"apc_paid":null,"fwci":9.7992,"has_fulltext":true,"cited_by_count":53,"citation_normalized_percentile":{"value":0.98881858,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":93,"max":100},"biblio":{"volume":"13","issue":"3","first_page":"4851","last_page":"4868"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10365","display_name":"Gastrointestinal motility and disorders","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10365","display_name":"Gastrointestinal motility and disorders","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10814","display_name":"Neuropeptides and Animal Physiology","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12237","display_name":"Congenital gastrointestinal and neural anomalies","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/serotonin","display_name":"serotonin","score":0.9959999918937683},{"id":"https://openalex.org/keywords/gastrointestinal-development","display_name":"gastrointestinal development","score":0.7229999899864197},{"id":"https://openalex.org/keywords/gastrointestinal-motility","display_name":"gastrointestinal motility","score":0.9789999723434448},{"id":"https://openalex.org/keywords/intestinal-inflammation","display_name":"intestinal inflammation","score":0.6489999890327454},{"id":"https://openalex.org/keywords/enterochromaffin-cells","display_name":"enterochromaffin cells","score":0.9819999933242798},{"id":"https://openalex.org/keywords/enteric-nervous-system","display_name":"enteric nervous system","score":0.9710000157356262},{"id":"https://openalex.org/keywords/serotonin-receptors","display_name":"serotonin receptors","score":0.9779999852180481},{"id":"https://openalex.org/keywords/gut-brain-axis","display_name":"gut-brain axis","score":0.7369999885559082},{"id":"https://openalex.org/keywords/functional-gastrointestinal-disorders","display_name":"functional gastrointestinal disorders","score":0.8949999809265137},{"id":"https://openalex.org/keywords/inflammatory-bowel-disease","display_name":"inflammatory bowel disease","score":0.7960000038146973},{"id":"https://openalex.org/keywords/neurogenesis","display_name":"neurogenesis","score":0.5389999747276306}],"concepts":[{"id":"https://openalex.org/C90423213","wikidata":"https://www.wikidata.org/wiki/Q568290","display_name":"Enterochromaffin cell","level":4,"score":0.9028099775314331},{"id":"https://openalex.org/C37000724","wikidata":"https://www.wikidata.org/wiki/Q50430226","display_name":"Serotonergic","level":4,"score":0.8492811918258667},{"id":"https://openalex.org/C2777439022","wikidata":"https://www.wikidata.org/wiki/Q586582","display_name":"Enteric nervous system","level":2,"score":0.7468008399009705},{"id":"https://openalex.org/C58207958","wikidata":"https://www.wikidata.org/wiki/Q33596","display_name":"Motility","level":2,"score":0.658617377281189},{"id":"https://openalex.org/C2775864247","wikidata":"https://www.wikidata.org/wiki/Q167934","display_name":"Serotonin","level":3,"score":0.642440140247345},{"id":"https://openalex.org/C2780512811","wikidata":"https://www.wikidata.org/wiki/Q11829360","display_name":"Gastrointestinal tract","level":2,"score":0.6343157291412354},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.633608877658844},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.5249911546707153},{"id":"https://openalex.org/C4746552","wikidata":"https://www.wikidata.org/wiki/Q1456827","display_name":"Neurogenesis","level":2,"score":0.5194670557975769},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.47658368945121765},{"id":"https://openalex.org/C10162356","wikidata":"https://www.wikidata.org/wiki/Q1135939","display_name":"Pathophysiology","level":2,"score":0.4401463568210602},{"id":"https://openalex.org/C529278444","wikidata":"https://www.wikidata.org/wiki/Q47273","display_name":"Central nervous system","level":2,"score":0.4241976737976074},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.414591908454895},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.32815465331077576},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3065264821052551},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.2806367874145508},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.23906159400939941},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.18969225883483887}],"mesh":[{"descriptor_ui":"D005769","descriptor_name":"Gastrointestinal Motility","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007249","descriptor_name":"Inflammation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011985","descriptor_name":"Receptors, Serotonin","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012701","descriptor_name":"Serotonin","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D041981","descriptor_name":"Gastrointestinal Tract","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1002/j.2040-4603.2023.tb00272.x","doi":"https://doi.org/10.1002/j.2040-4603.2023.tb00272.x","is_oa":false,"landing_page_url":"https://doi.org/10.1002/j.2040-4603.2023.tb00272.x","pdf_url":null,"source":{"id":"https://openalex.org/S18747983","display_name":"Comprehensive physiology","issn_l":"2040-4603","issn":["2040-4603"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","norway-1","poland-200","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Comprehensive Physiology","raw_type":"journal-article"},{"id":"doi:10.1002/cphy.c220024","doi":"https://doi.org/10.1002/cphy.c220024","is_oa":true,"landing_page_url":"https://doi.org/10.1002/cphy.c220024","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/cphy.c220024","source":{"id":"https://openalex.org/S18747983","display_name":"Comprehensive physiology","issn_l":"2040-4603","issn":["2040-4603"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","norway-1","poland-200","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Comprehensive Physiology","raw_type":"other"},{"id":"pmid:37358510","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37358510","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Comprehensive Physiology","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:10373054","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10373054","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10373054/pdf/nihms-1916082.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Compr Physiol","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1002/cphy.c220024","doi":"https://doi.org/10.1002/cphy.c220024","is_oa":true,"landing_page_url":"https://doi.org/10.1002/cphy.c220024","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/cphy.c220024","source":{"id":"https://openalex.org/S18747983","display_name":"Comprehensive physiology","issn_l":"2040-4603","issn":["2040-4603"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","norway-1","poland-200","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Comprehensive Physiology","raw_type":"other"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8371999859809875}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2281486809","display_name":null,"funder_award_id":"R01-NS015547","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G3508353688","display_name":null,"funder_award_id":"PR160365","funder_id":"https://openalex.org/F4320306078","funder_display_name":"U.S. Department of Defense"},{"id":"https://openalex.org/G4000206592","display_name":"MICROENVIRONMENT IN ENTERIC NEURON DEVELOPMENT","funder_award_id":"5r01ns015547-39","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G410083633","display_name":"The role of mucosal serotonin in visceral nociception and gut motility","funder_award_id":"F32DK132810","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G6252877636","display_name":"Linkage of s100a10 (p11) to enteric 5-HT4-mediated serotonergic signaling roles in GI motility, enteric nervous system development, and co-morbid dysfunction of gut and brain","funder_award_id":"R01DK126644","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G7004882305","display_name":null,"funder_award_id":"L40 DK134006","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G807963871","display_name":"A Prospective Study Examining the Role of Gestational SSRI Exposure in the Development of Functional Gastrointestinal Disorders","funder_award_id":"R01DK130517","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G991970852","display_name":"Vitamin D Receptor Regulation of Microbiota in Intestinal Epithelia","funder_award_id":"R01DK105118","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"}],"funders":[{"id":"https://openalex.org/F4320306078","display_name":"U.S. Department of Defense","ror":"https://ror.org/0447fe631"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"},{"id":"https://openalex.org/F4320337359","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4382011844.pdf","grobid_xml":"https://content.openalex.org/works/W4382011844.grobid-xml"},"referenced_works_count":242,"referenced_works":["https://openalex.org/W15783726","https://openalex.org/W1454893841","https://openalex.org/W1487053105","https://openalex.org/W1501397556","https://openalex.org/W1517389358","https://openalex.org/W1519724934","https://openalex.org/W1522776071","https://openalex.org/W1537465253","https://openalex.org/W1547288529","https://openalex.org/W1548254511","https://openalex.org/W1576727246","https://openalex.org/W1586749756","https://openalex.org/W1593049722","https://openalex.org/W1595141034","https://openalex.org/W1644261241","https://openalex.org/W1717626108","https://openalex.org/W1839541123","https://openalex.org/W1858131570","https://openalex.org/W1859201630","https://openalex.org/W1869902845","https://openalex.org/W1894142717","https://openalex.org/W1897119081","https://openalex.org/W1907864108","https://openalex.org/W1909691032","https://openalex.org/W1943555183","https://openalex.org/W1963579052","https://openalex.org/W1968211000","https://openalex.org/W1969144895","https://openalex.org/W1969426171","https://openalex.org/W1972348334","https://openalex.org/W1973001367","https://openalex.org/W1974267427","https://openalex.org/W1974584320","https://openalex.org/W1976114760","https://openalex.org/W1976200262","https://openalex.org/W1976476429","https://openalex.org/W1978362426","https://openalex.org/W1979264182","https://openalex.org/W1980710038","https://openalex.org/W1985025206","https://openalex.org/W1987488421","https://openalex.org/W1990427136","https://openalex.org/W1993351522","https://openalex.org/W1993725963","https://openalex.org/W1993951693","https://openalex.org/W1995030215","https://openalex.org/W1995909110","https://openalex.org/W1997066133","https://openalex.org/W1997242740","https://openalex.org/W1997311974","https://openalex.org/W1997608252","https://openalex.org/W1999720993","https://openalex.org/W2002456808","https://openalex.org/W2002569475","https://openalex.org/W2002852335","https://openalex.org/W2004862250","https://openalex.org/W2005575554","https://openalex.org/W2007486557","https://openalex.org/W2008019573","https://openalex.org/W2008709508","https://openalex.org/W2010749425","https://openalex.org/W2012574771","https://openalex.org/W2014001501","https://openalex.org/W2014162693","https://openalex.org/W2014814979","https://openalex.org/W2020248944","https://openalex.org/W2021959823","https://openalex.org/W2022461628","https://openalex.org/W2022783819","https://openalex.org/W2026424285","https://openalex.org/W2026987288","https://openalex.org/W2027425813","https://openalex.org/W2028164506","https://openalex.org/W2029067814","https://openalex.org/W2029963792","https://openalex.org/W2032197145","https://openalex.org/W2032409964","https://openalex.org/W2032962966","https://openalex.org/W2033028213","https://openalex.org/W2033386838","https://openalex.org/W2035663126","https://openalex.org/W2039658386","https://openalex.org/W2041055188","https://openalex.org/W2041228343","https://openalex.org/W2042335480","https://openalex.org/W2042615016","https://openalex.org/W2043428150","https://openalex.org/W2045323481","https://openalex.org/W2048727351","https://openalex.org/W2049943730","https://openalex.org/W2051692635","https://openalex.org/W2052554443","https://openalex.org/W2052694209","https://openalex.org/W2053195651","https://openalex.org/W2053468878","https://openalex.org/W2053810512","https://openalex.org/W2053908167","https://openalex.org/W2054199244","https://openalex.org/W2060266012","https://openalex.org/W2063601395","https://openalex.org/W2064201279","https://openalex.org/W2066504739","https://openalex.org/W2066859126","https://openalex.org/W2067086485","https://openalex.org/W2068454300","https://openalex.org/W2069142753","https://openalex.org/W2069643295","https://openalex.org/W2070872078","https://openalex.org/W2071150481","https://openalex.org/W2071327709","https://openalex.org/W2071385796","https://openalex.org/W2072553133","https://openalex.org/W2073056198","https://openalex.org/W2073519139","https://openalex.org/W2074992169","https://openalex.org/W2075335843","https://openalex.org/W2075583206","https://openalex.org/W2078233092","https://openalex.org/W2079961396","https://openalex.org/W2080733464","https://openalex.org/W2082752112","https://openalex.org/W2083824794","https://openalex.org/W2085139899","https://openalex.org/W2086075088","https://openalex.org/W2087048554","https://openalex.org/W2087244895","https://openalex.org/W2088684629","https://openalex.org/W2090377492","https://openalex.org/W2092446347","https://openalex.org/W2093666272","https://openalex.org/W2095139743","https://openalex.org/W2097566770","https://openalex.org/W2097785193","https://openalex.org/W2098073452","https://openalex.org/W2098518381","https://openalex.org/W2099590846","https://openalex.org/W2104220482","https://openalex.org/W2104428938","https://openalex.org/W2107044225","https://openalex.org/W2107634021","https://openalex.org/W2108730634","https://openalex.org/W2110726089","https://openalex.org/W2116921598","https://openalex.org/W2117296179","https://openalex.org/W2118366970","https://openalex.org/W2118507010","https://openalex.org/W2118741643","https://openalex.org/W2121087428","https://openalex.org/W2123301163","https://openalex.org/W2124549431","https://openalex.org/W2124571312","https://openalex.org/W2128077096","https://openalex.org/W2128085120","https://openalex.org/W2130505437","https://openalex.org/W2132703507","https://openalex.org/W2132910924","https://openalex.org/W2134032226","https://openalex.org/W2136328934","https://openalex.org/W2136771602","https://openalex.org/W2139666900","https://openalex.org/W2141093120","https://openalex.org/W2141910384","https://openalex.org/W2143198897","https://openalex.org/W2143837967","https://openalex.org/W2145408858","https://openalex.org/W2145496597","https://openalex.org/W2147589751","https://openalex.org/W2147928251","https://openalex.org/W2148833844","https://openalex.org/W2152800208","https://openalex.org/W2153192132","https://openalex.org/W2153655311","https://openalex.org/W2153657359","https://openalex.org/W2154627001","https://openalex.org/W2155948158","https://openalex.org/W2156291426","https://openalex.org/W2156345396","https://openalex.org/W2156563701","https://openalex.org/W2158148601","https://openalex.org/W2160204304","https://openalex.org/W2160300693","https://openalex.org/W2161066198","https://openalex.org/W2161996137","https://openalex.org/W2163161835","https://openalex.org/W2167343594","https://openalex.org/W2168678503","https://openalex.org/W2168959836","https://openalex.org/W2168967776","https://openalex.org/W2171308890","https://openalex.org/W2180083287","https://openalex.org/W2182981659","https://openalex.org/W2231949275","https://openalex.org/W2264932050","https://openalex.org/W2274531174","https://openalex.org/W2279976006","https://openalex.org/W2284801858","https://openalex.org/W2287682542","https://openalex.org/W2290360434","https://openalex.org/W2294340540","https://openalex.org/W2301096710","https://openalex.org/W2305155199","https://openalex.org/W2317137223","https://openalex.org/W2319166398","https://openalex.org/W2334494022","https://openalex.org/W2343547480","https://openalex.org/W2376330683","https://openalex.org/W2412916341","https://openalex.org/W2418959002","https://openalex.org/W2460164747","https://openalex.org/W2485997503","https://openalex.org/W2517794688","https://openalex.org/W2540134543","https://openalex.org/W2564545009","https://openalex.org/W2601264620","https://openalex.org/W2607428872","https://openalex.org/W2658508676","https://openalex.org/W2738971267","https://openalex.org/W2765842447","https://openalex.org/W2788398310","https://openalex.org/W2789833028","https://openalex.org/W2804475579","https://openalex.org/W2806531878","https://openalex.org/W2883884554","https://openalex.org/W2943725638","https://openalex.org/W2949693884","https://openalex.org/W2971786247","https://openalex.org/W3011631449","https://openalex.org/W3080830477","https://openalex.org/W3081339611","https://openalex.org/W3082963850","https://openalex.org/W3088372348","https://openalex.org/W3111272930","https://openalex.org/W3122128474","https://openalex.org/W3135543011","https://openalex.org/W3156202411","https://openalex.org/W3198362280","https://openalex.org/W3206905653","https://openalex.org/W4213393192","https://openalex.org/W4214888288","https://openalex.org/W4220736919","https://openalex.org/W4221082819","https://openalex.org/W4224258094"],"related_works":["https://openalex.org/W7096411003","https://openalex.org/W2134737608","https://openalex.org/W2600368530","https://openalex.org/W1993759344","https://openalex.org/W2155948158","https://openalex.org/W2089922699","https://openalex.org/W79347276","https://openalex.org/W2033848049","https://openalex.org/W4214888288","https://openalex.org/W2564545009"],"abstract_inverted_index":{"Although":[0],"it":[1],"is":[2,22,30],"most":[3],"well-known":[4],"for":[5],"its":[6,87],"roles":[7,76],"in":[8,24,42,66,79,89],"central":[9],"nervous":[10,50],"system":[11,51],"(CNS)":[12],"function,":[13],"the":[14,25,38,48,90],"vast":[15],"majority":[16],"of":[17,37,47,59,77,92,94],"serotonin,":[18],"or":[19],"5-hydroxytryptamine":[20],"(5-HT),":[21],"produced":[23],"gastrointestinal":[26],"(GI)":[27],"tract.":[28],"5-HT":[29,62,78],"synthesized":[31],"mostly":[32],"by":[33,45],"enterochromaffin":[34],"(EC)":[35],"cells":[36],"GI":[39,54],"epithelium":[40],"and,":[41],"small":[43],"part,":[44],"neurons":[46],"enteric":[49],"(ENS).":[52],"The":[53,75],"tract":[55],"contains":[56],"an":[57],"array":[58],"broadly":[60],"distributed":[61],"receptors,":[63],"which":[64],"participate":[65],"functions":[67,81],"such":[68],"as":[69,84,86],"motility,":[70],"sensation,":[71],"inflammation,":[72],"and":[73,98],"neurogenesis.":[74],"these":[80],"are":[82],"reviewed,":[83],"well":[85],"role":[88],"pathophysiology":[91],"disorders":[93],"gut-brain":[95],"interaction":[96],"(DGBIs)":[97],"inflammatory":[99],"bowel":[100],"diseases":[101],"(IBD).":[102],"\u00a9":[103],"2023":[104],"American":[105],"Physiological":[106],"Society.":[107],"Compr":[108],"Physiol":[109],"13:4851-4868,":[110],"2023.":[111]},"counts_by_year":[{"year":2026,"cited_by_count":21},{"year":2025,"cited_by_count":14},{"year":2024,"cited_by_count":16},{"year":2023,"cited_by_count":2}],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2023-06-27T00:00:00"}