{"id":"https://openalex.org/W4382010516","doi":"https://doi.org/10.1007/s10620-023-08003-2","title":"The Many Faces of Primary Sclerosing Cholangitis: Controversy Abounds","display_name":"The Many Faces of Primary Sclerosing Cholangitis: Controversy Abounds","publication_year":2023,"publication_date":"2023-06-26","ids":{"openalex":"https://openalex.org/W4382010516","doi":"https://doi.org/10.1007/s10620-023-08003-2","pmid":"https://pubmed.ncbi.nlm.nih.gov/37358638"},"language":"en","primary_location":{"id":"doi:10.1007/s10620-023-08003-2","doi":"https://doi.org/10.1007/s10620-023-08003-2","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s10620-023-08003-2","pdf_url":null,"source":{"id":"https://openalex.org/S194656152","display_name":"Digestive Diseases and Sciences","issn_l":"0163-2116","issn":["0163-2116","1573-2568"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Digestive Diseases and Sciences","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5053913663","display_name":"Brian J. Wentworth","orcid":"https://orcid.org/0000-0003-3642-887X","observed_orcids":["https://orcid.org/0000-0003-3642-887X"]},"institutions":[{"id":"https://openalex.org/I51556381","display_name":"University of Virginia","ror":"https://ror.org/0153tk833","country_code":"US","type":"education","lineage":["https://openalex.org/I51556381"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Brian J. Wentworth","raw_affiliation_strings":["Division of Gastroenterology and Hepatology, School of Medicine, University of Virginia, PO Box 800708, Charlottesville, VA, 22908, USA. bw8xz@uvahealth.org","Division of Gastroenterology and Hepatology, School of Medicine, University of Virginia, PO Box 800708, Charlottesville, VA, 22908, USA"],"raw_orcid":"https://orcid.org/0000-0003-3642-887X","affiliations":[{"raw_affiliation_string":"Division of Gastroenterology and Hepatology, School of Medicine, University of Virginia, PO Box 800708, Charlottesville, VA, 22908, USA. bw8xz@uvahealth.org","institution_ids":["https://openalex.org/I51556381"]},{"raw_affiliation_string":"Division of Gastroenterology and Hepatology, School of Medicine, University of Virginia, PO Box 800708, Charlottesville, VA, 22908, USA","institution_ids":["https://openalex.org/I51556381"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022962738","display_name":"Rachita Khot","orcid":"https://orcid.org/0000-0003-3448-4528","observed_orcids":["https://orcid.org/0000-0003-3448-4528"]},"institutions":[{"id":"https://openalex.org/I2799765794","display_name":"University of Virginia Health System","ror":"https://ror.org/00wn7d965","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799765794"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rachita Khot","raw_affiliation_strings":["Department of Radiology and Medical Imaging, University of Virginia Health System, Charlottesville, VA, USA"],"raw_orcid":"https://orcid.org/0000-0003-3448-4528","affiliations":[{"raw_affiliation_string":"Department of Radiology and Medical Imaging, University of Virginia Health System, Charlottesville, VA, USA","institution_ids":["https://openalex.org/I2799765794"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5027753564","display_name":"Stephen Hugh Caldwell","orcid":"https://orcid.org/0000-0003-1323-4191","observed_orcids":["https://orcid.org/0000-0003-1323-4191"]},"institutions":[{"id":"https://openalex.org/I51556381","display_name":"University of Virginia","ror":"https://ror.org/0153tk833","country_code":"US","type":"education","lineage":["https://openalex.org/I51556381"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Stephen H. Caldwell","raw_affiliation_strings":["Division of Gastroenterology and Hepatology, School of Medicine, University of Virginia, PO Box 800708, Charlottesville, VA, 22908, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Gastroenterology and Hepatology, School of Medicine, University of Virginia, PO Box 800708, Charlottesville, VA, 22908, USA","institution_ids":["https://openalex.org/I51556381"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5053913663"],"corresponding_institution_ids":["https://openalex.org/I51556381"],"apc_list":{"value":3990,"currency":"USD","value_usd":3990},"apc_paid":null,"fwci":0.0831,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.1223162,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":96},"biblio":{"volume":"68","issue":"9","first_page":"3514","last_page":"3526"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11834","display_name":"Liver Diseases and Immunity","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11834","display_name":"Liver Diseases and Immunity","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12460","display_name":"Pediatric Hepatobiliary Diseases and Treatments","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10337","display_name":"Liver Disease and Transplantation","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/primary-sclerosing-cholangitis","display_name":"primary sclerosing cholangitis","score":1.0},{"id":"https://openalex.org/keywords/disease-heterogeneity","display_name":"disease heterogeneity","score":0.8450000286102295},{"id":"https://openalex.org/keywords/ursodeoxycholic-acid","display_name":"ursodeoxycholic acid","score":0.9200000166893005},{"id":"https://openalex.org/keywords/magnetic-resonance-imaging","display_name":"magnetic resonance imaging","score":0.7919999957084656},{"id":"https://openalex.org/keywords/liver-transplantation","display_name":"liver transplantation","score":0.7139999866485596},{"id":"https://openalex.org/keywords/liver-cirrhosis","display_name":"liver cirrhosis","score":0.7649999856948853},{"id":"https://openalex.org/keywords/portal-hypertension","display_name":"portal hypertension","score":0.6660000085830688},{"id":"https://openalex.org/keywords/disease-modifying-therapy","display_name":"disease-modifying therapy","score":0.6510000228881836}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8548575639724731},{"id":"https://openalex.org/C2780615123","wikidata":"https://www.wikidata.org/wiki/Q1058608","display_name":"Primary sclerosing cholangitis","level":3,"score":0.8356083035469055},{"id":"https://openalex.org/C2779609443","wikidata":"https://www.wikidata.org/wiki/Q1368191","display_name":"Liver transplantation","level":3,"score":0.7186618447303772},{"id":"https://openalex.org/C41260117","wikidata":"https://www.wikidata.org/wiki/Q668064","display_name":"Hepatology","level":2,"score":0.6731008291244507},{"id":"https://openalex.org/C2779399171","wikidata":"https://www.wikidata.org/wiki/Q1483951","display_name":"Malignancy","level":2,"score":0.5605348348617554},{"id":"https://openalex.org/C2777214474","wikidata":"https://www.wikidata.org/wiki/Q147778","display_name":"Cirrhosis","level":2,"score":0.47133469581604004},{"id":"https://openalex.org/C2777075537","wikidata":"https://www.wikidata.org/wiki/Q929737","display_name":"Liver disease","level":2,"score":0.45247402787208557},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.42015761137008667},{"id":"https://openalex.org/C2778456037","wikidata":"https://www.wikidata.org/wiki/Q133244","display_name":"Jaundice","level":2,"score":0.4156070053577423},{"id":"https://openalex.org/C2909339193","wikidata":"https://www.wikidata.org/wiki/Q105196","display_name":"Transplant surgery","level":3,"score":0.4138222932815552},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4126847982406616},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.36594313383102417},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.36487412452697754},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.3590551018714905},{"id":"https://openalex.org/C2911091166","wikidata":"https://www.wikidata.org/wiki/Q106419912","display_name":"Transplantation","level":2,"score":0.3365047872066498},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.2703767418861389}],"mesh":[{"descriptor_ui":"D005682","descriptor_name":"Gadolinium","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008103","descriptor_name":"Liver Cirrhosis","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D015209","descriptor_name":"Cholangitis, Sclerosing","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D015209","descriptor_name":"Cholangitis, Sclerosing","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D015209","descriptor_name":"Cholangitis, Sclerosing","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D016031","descriptor_name":"Liver Transplantation","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1007/s10620-023-08003-2","doi":"https://doi.org/10.1007/s10620-023-08003-2","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s10620-023-08003-2","pdf_url":null,"source":{"id":"https://openalex.org/S194656152","display_name":"Digestive Diseases and Sciences","issn_l":"0163-2116","issn":["0163-2116","1573-2568"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Digestive Diseases and Sciences","raw_type":"journal-article"},{"id":"pmid:37358638","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37358638","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Digestive diseases and sciences","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9940000176429749}],"study_designs":[],"awards":[{"id":"https://openalex.org/G406546074","display_name":null,"funder_award_id":"50031","funder_id":"https://openalex.org/F4320308400","funder_display_name":"American Association for the Study of Liver Diseases"}],"funders":[{"id":"https://openalex.org/F4320308400","display_name":"American Association for the Study of Liver Diseases","ror":"https://ror.org/005tjs461"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":100,"referenced_works":["https://openalex.org/W16640574","https://openalex.org/W28794996","https://openalex.org/W1492604623","https://openalex.org/W1507977629","https://openalex.org/W1566103919","https://openalex.org/W1851143213","https://openalex.org/W1869119189","https://openalex.org/W1932825138","https://openalex.org/W1966360400","https://openalex.org/W1967353454","https://openalex.org/W1967931951","https://openalex.org/W1968896691","https://openalex.org/W1970023010","https://openalex.org/W1971108757","https://openalex.org/W1975213560","https://openalex.org/W1977924019","https://openalex.org/W1980642040","https://openalex.org/W1983054413","https://openalex.org/W1987523828","https://openalex.org/W1989253917","https://openalex.org/W1993470842","https://openalex.org/W1995534781","https://openalex.org/W1995850023","https://openalex.org/W2001536883","https://openalex.org/W2005508238","https://openalex.org/W2005901103","https://openalex.org/W2013504081","https://openalex.org/W2023000637","https://openalex.org/W2026781960","https://openalex.org/W2028005970","https://openalex.org/W2044009298","https://openalex.org/W2053194502","https://openalex.org/W2054103320","https://openalex.org/W2060437861","https://openalex.org/W2061887879","https://openalex.org/W2063055202","https://openalex.org/W2065665184","https://openalex.org/W2070826820","https://openalex.org/W2079540238","https://openalex.org/W2080304201","https://openalex.org/W2090694192","https://openalex.org/W2091071330","https://openalex.org/W2102005215","https://openalex.org/W2102720867","https://openalex.org/W2108856666","https://openalex.org/W2114294004","https://openalex.org/W2122407733","https://openalex.org/W2129116090","https://openalex.org/W2132474120","https://openalex.org/W2133403920","https://openalex.org/W2140036864","https://openalex.org/W2154780499","https://openalex.org/W2155961553","https://openalex.org/W2169262628","https://openalex.org/W2170030098","https://openalex.org/W2289861039","https://openalex.org/W2312938814","https://openalex.org/W2313319643","https://openalex.org/W2343310341","https://openalex.org/W2415106274","https://openalex.org/W2460505725","https://openalex.org/W2552444756","https://openalex.org/W2564368713","https://openalex.org/W2605729742","https://openalex.org/W2632697003","https://openalex.org/W2738454635","https://openalex.org/W2745107259","https://openalex.org/W2769224264","https://openalex.org/W2773807652","https://openalex.org/W2775857256","https://openalex.org/W2790255143","https://openalex.org/W2800897086","https://openalex.org/W2801940029","https://openalex.org/W2802270089","https://openalex.org/W2886703787","https://openalex.org/W2894736184","https://openalex.org/W2905044063","https://openalex.org/W2921274644","https://openalex.org/W2995815973","https://openalex.org/W3027906267","https://openalex.org/W3045660148","https://openalex.org/W3087505454","https://openalex.org/W3119803962","https://openalex.org/W3130164315","https://openalex.org/W3162807610","https://openalex.org/W3187119339","https://openalex.org/W3192953899","https://openalex.org/W3197197037","https://openalex.org/W4200402643","https://openalex.org/W4233893512","https://openalex.org/W4239828441","https://openalex.org/W4240877935","https://openalex.org/W4281249587","https://openalex.org/W4283215432","https://openalex.org/W4294487055","https://openalex.org/W4295048810","https://openalex.org/W4303946449","https://openalex.org/W4307955345","https://openalex.org/W4308473467","https://openalex.org/W4309480412"],"related_works":["https://openalex.org/W2299980382","https://openalex.org/W2737450878","https://openalex.org/W1571158377","https://openalex.org/W1964143886","https://openalex.org/W1983086860","https://openalex.org/W2042515730","https://openalex.org/W2121484013","https://openalex.org/W1993041508","https://openalex.org/W2767268527","https://openalex.org/W2010895041"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2023-06-27T00:00:00"}