{"id":"https://openalex.org/W4381955893","doi":"https://doi.org/10.51847/q59uyvrmy3","title":"Bioavailability study of Posaconazole in rats after oral Poloxamer P188 Nano-micelles and oral Posaconazole pure drug","display_name":"Bioavailability study of Posaconazole in rats after oral Poloxamer P188 Nano-micelles and oral Posaconazole pure drug","publication_year":2023,"publication_date":"2023-01-01","ids":{"openalex":"https://openalex.org/W4381955893","doi":"https://doi.org/10.51847/q59uyvrmy3"},"language":"en","primary_location":{"id":"doi:10.51847/q59uyvrmy3","doi":"https://doi.org/10.51847/q59uyvrmy3","is_oa":true,"landing_page_url":"https://doi.org/10.51847/q59uyvrmy3","pdf_url":"https://japer.in/storage/files/article/b084f8fd-fddd-46e2-b0bb-59de23e02689-ZqkG3NLoHppSHemc/japer-vol-13-iss-2-140-143-8192.pdf","source":{"id":"https://openalex.org/S4210230375","display_name":"Journal Of Advanced Pharmacy Education And Research","issn_l":"2249-3379","issn":["2249-3379"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["poland-20"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Advanced Pharmacy Education and Research","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W4381955893"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://japer.in/storage/files/article/b084f8fd-fddd-46e2-b0bb-59de23e02689-ZqkG3NLoHppSHemc/japer-vol-13-iss-2-140-143-8192.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5040012347","display_name":"Alaa Abdulelah Abdulqader","orcid":"https://orcid.org/0000-0002-5071-690X","observed_orcids":["https://orcid.org/0000-0002-5071-690X"]},"institutions":[{"id":"https://openalex.org/I72539421","display_name":"University of Tikrit","ror":"https://ror.org/01zfzax10","country_code":"IQ","type":"education","lineage":["https://openalex.org/I72539421"]}],"countries":["IQ"],"is_corresponding":false,"raw_author_name":"Alaa Abdulelah Abdulqader","raw_affiliation_strings":["Department of Pharmaceutics, College of Pharmacy, University of Tikrit, Salaheddin, Iraq"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmaceutics, College of Pharmacy, University of Tikrit, Salaheddin, Iraq","institution_ids":["https://openalex.org/I72539421"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5071168267","display_name":"Nawal Ayash Rajab","orcid":"https://orcid.org/0000-0001-8777-0304","observed_orcids":["https://orcid.org/0000-0001-8777-0304"]},"institutions":[{"id":"https://openalex.org/I135120706","display_name":"University of Baghdad","ror":"https://ror.org/007f1da21","country_code":"IQ","type":"education","lineage":["https://openalex.org/I135120706"]}],"countries":["IQ"],"is_corresponding":false,"raw_author_name":"Nawal Ayash Rajab","raw_affiliation_strings":["Department of Pharmaceutics, College of Pharmacy, University of Baghdad, Baghdad, Iraq"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmaceutics, College of Pharmacy, University of Baghdad, Baghdad, Iraq","institution_ids":["https://openalex.org/I135120706"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.3127,"has_fulltext":true,"cited_by_count":13,"citation_normalized_percentile":{"value":0.73514077,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":98},"biblio":{"volume":"13","issue":"2","first_page":"140","last_page":"143"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10256","display_name":"Drug Solubulity and Delivery Systems","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10256","display_name":"Drug Solubulity and Delivery Systems","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10920","display_name":"Advanced Drug Delivery Systems","score":0.002300000051036477,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10704","display_name":"Advancements in Transdermal Drug Delivery","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/posaconazole","display_name":"posaconazole","score":1.0},{"id":"https://openalex.org/keywords/bioavailability","display_name":"bioavailability","score":0.9010000228881836},{"id":"https://openalex.org/keywords/nanomicelles","display_name":"nanomicelles","score":0.9800000190734863},{"id":"https://openalex.org/keywords/oral-drug-delivery","display_name":"oral drug delivery","score":0.8360000252723694},{"id":"https://openalex.org/keywords/poorly-water-soluble-drugs","display_name":"poorly water-soluble drugs","score":0.8479999899864197},{"id":"https://openalex.org/keywords/triazole-antifungals","display_name":"triazole antifungals","score":0.8220000267028809},{"id":"https://openalex.org/keywords/oral-administration","display_name":"oral administration","score":0.35499998927116394},{"id":"https://openalex.org/keywords/rats","display_name":"rats","score":0.421999990940094}],"concepts":[{"id":"https://openalex.org/C2778566413","wikidata":"https://www.wikidata.org/wiki/Q906453","display_name":"Posaconazole","level":4,"score":0.8960587978363037},{"id":"https://openalex.org/C181389837","wikidata":"https://www.wikidata.org/wiki/Q461809","display_name":"Bioavailability","level":2,"score":0.7772250771522522},{"id":"https://openalex.org/C101335993","wikidata":"https://www.wikidata.org/wiki/Q408943","display_name":"Poloxamer","level":4,"score":0.6639958024024963},{"id":"https://openalex.org/C2780035454","wikidata":"https://www.wikidata.org/wiki/Q8386","display_name":"Drug","level":2,"score":0.6004723310470581},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.5994182825088501},{"id":"https://openalex.org/C2780306666","wikidata":"https://www.wikidata.org/wiki/Q7225971","display_name":"Poloxamer 407","level":5,"score":0.5569298267364502},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4121497869491577},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.3439302444458008},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3214232325553894},{"id":"https://openalex.org/C16005928","wikidata":"https://www.wikidata.org/wiki/Q171171","display_name":"Dermatology","level":1,"score":0.1443173885345459},{"id":"https://openalex.org/C2779548794","wikidata":"https://www.wikidata.org/wiki/Q578726","display_name":"Antifungal","level":2,"score":0.12738531827926636},{"id":"https://openalex.org/C2777071850","wikidata":"https://www.wikidata.org/wiki/Q411229","display_name":"Itraconazole","level":3,"score":0.11009407043457031},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.07029888033866882},{"id":"https://openalex.org/C521977710","wikidata":"https://www.wikidata.org/wiki/Q81163","display_name":"Polymer","level":2,"score":0.0},{"id":"https://openalex.org/C15920480","wikidata":"https://www.wikidata.org/wiki/Q421281","display_name":"Copolymer","level":3,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.51847/q59uyvrmy3","doi":"https://doi.org/10.51847/q59uyvrmy3","is_oa":true,"landing_page_url":"https://doi.org/10.51847/q59uyvrmy3","pdf_url":"https://japer.in/storage/files/article/b084f8fd-fddd-46e2-b0bb-59de23e02689-ZqkG3NLoHppSHemc/japer-vol-13-iss-2-140-143-8192.pdf","source":{"id":"https://openalex.org/S4210230375","display_name":"Journal Of Advanced Pharmacy Education And Research","issn_l":"2249-3379","issn":["2249-3379"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["poland-20"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Advanced Pharmacy Education and Research","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.51847/q59uyvrmy3","doi":"https://doi.org/10.51847/q59uyvrmy3","is_oa":true,"landing_page_url":"https://doi.org/10.51847/q59uyvrmy3","pdf_url":"https://japer.in/storage/files/article/b084f8fd-fddd-46e2-b0bb-59de23e02689-ZqkG3NLoHppSHemc/japer-vol-13-iss-2-140-143-8192.pdf","source":{"id":"https://openalex.org/S4210230375","display_name":"Journal Of Advanced Pharmacy Education And Research","issn_l":"2249-3379","issn":["2249-3379"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["poland-20"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Advanced Pharmacy Education and Research","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.8371999859809875}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320310603","display_name":"University of Baghdad","ror":"https://ror.org/007f1da21"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4381955893.pdf","grobid_xml":"https://content.openalex.org/works/W4381955893.grobid-xml"},"referenced_works_count":13,"referenced_works":["https://openalex.org/W1976779766","https://openalex.org/W2027820615","https://openalex.org/W2074257474","https://openalex.org/W2288824982","https://openalex.org/W2396801144","https://openalex.org/W2561662825","https://openalex.org/W2747119619","https://openalex.org/W2971410756","https://openalex.org/W3006987776","https://openalex.org/W3190329725","https://openalex.org/W4200576232","https://openalex.org/W4242787642","https://openalex.org/W4313437687"],"related_works":["https://openalex.org/W4388342755","https://openalex.org/W6920694641","https://openalex.org/W7124131936","https://openalex.org/W2561510424","https://openalex.org/W2067101775","https://openalex.org/W6930857068","https://openalex.org/W4317518150","https://openalex.org/W2885036289","https://openalex.org/W4362696166","https://openalex.org/W4409409330"],"abstract_inverted_index":{"Posaconazole":[0],"(POCZ)":[1],"is":[2,15],"a":[3,40],"triazole":[4],"antifungal":[5],"with":[6,39,51,73],"poor":[7],"solubility":[8],"and":[9,25,44,61],"low":[10],"bioavailability,":[11],"so":[12],"this":[13,32],"work":[14],"aimed":[16],"to":[17,66],"compare":[18],"between":[19],"bioavailability":[20],"parameters":[21],"of":[22,42,56,58],"pure":[23,59],"POCZ":[24,29,60,62],"the":[26],"prepared":[27],"lyophilized":[28],"nano-micelles.":[30],"In":[31],"study,":[33],"twelve":[34],"Wistar":[35],"rats":[36,67],"were":[37],"used":[38],"weight":[41],"200\u00b120g":[43],"divided":[45],"into":[46],"twice":[47],"groups":[48],"(each":[49],"group":[50],"six":[52],"animals).":[53],"The":[54,75],"dose":[55],"10mg/kg":[57],"nano-micelles":[63],"was":[64],"administered":[65],"by":[68],"oral":[69],"gavage":[70],"after":[71],"reconstitution":[72],"water.":[74],"determina":[76]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":3}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2023-06-26T00:00:00"}