{"id":"https://openalex.org/W4381892929","doi":"https://doi.org/10.1093/humrep/dead093.331","title":"O-277 Safety of pregnancy after early breast cancer in young women with hormone receptor-positive disease: a systematic review and meta-analysis","display_name":"O-277 Safety of pregnancy after early breast cancer in young women with hormone receptor-positive disease: a systematic review and meta-analysis","publication_year":2023,"publication_date":"2023-06-01","ids":{"openalex":"https://openalex.org/W4381892929","doi":"https://doi.org/10.1093/humrep/dead093.331"},"language":"en","primary_location":{"id":"doi:10.1093/humrep/dead093.331","doi":"https://doi.org/10.1093/humrep/dead093.331","is_oa":true,"landing_page_url":"https://doi.org/10.1093/humrep/dead093.331","pdf_url":"https://academic.oup.com/humrep/article-pdf/38/Supplement_1/dead093.331/50786275/dead093.331.pdf","source":{"id":"https://openalex.org/S127900037","display_name":"Human Reproduction","issn_l":"0268-1161","issn":["0268-1161","1460-2350"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Human Reproduction","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/humrep/article-pdf/38/Supplement_1/dead093.331/50786275/dead093.331.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5021765093","display_name":"Luca Arecco","orcid":"https://orcid.org/0000-0002-3818-0364","observed_orcids":["https://orcid.org/0000-0002-3818-0364"]},"institutions":[{"id":"https://openalex.org/I4210146472","display_name":"Ospedale Policlinico San Martino","ror":"https://ror.org/04d7es448","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210146472","https://openalex.org/I4210153126","https://openalex.org/I4405264730"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"L Arecco","raw_affiliation_strings":["IRCCS San Martino Policlinic Hospital, Department of Medical Oncology- U.O.C. Clinica di Oncologia Medica , Genova, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"IRCCS San Martino Policlinic Hospital, Department of Medical Oncology- U.O.C. Clinica di Oncologia Medica , Genova, Italy","institution_ids":["https://openalex.org/I4210146472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022289263","display_name":"Eva Blondeaux","orcid":"https://orcid.org/0000-0001-9566-4579","observed_orcids":["https://orcid.org/0000-0001-9566-4579"]},"institutions":[{"id":"https://openalex.org/I4210146472","display_name":"Ospedale Policlinico San Martino","ror":"https://ror.org/04d7es448","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210146472","https://openalex.org/I4210153126","https://openalex.org/I4405264730"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"E Blondeaux","raw_affiliation_strings":["IRCCS San Martino Policlinic Hospital, Department of Clinic Epidemiology , Genova, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"IRCCS San Martino Policlinic Hospital, Department of Clinic Epidemiology , Genova, Italy","institution_ids":["https://openalex.org/I4210146472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010728834","display_name":"Elene Mariamidze","orcid":"https://orcid.org/0000-0001-8838-9193","observed_orcids":["https://orcid.org/0000-0001-8838-9193"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"E Mariamidze","raw_affiliation_strings":["Todua Clinic, Department of Oncology and Hematology , Tiblisi, Georgia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Todua Clinic, Department of Oncology and Hematology , Tiblisi, Georgia","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041303355","display_name":"S. Begijanashvili","orcid":"https://orcid.org/0000-0003-0156-5110","observed_orcids":["https://orcid.org/0000-0003-0156-5110"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"S Begijanashvili","raw_affiliation_strings":["American Hospital, Clinical Oncology Department- , Tiblisi, Georgia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"American Hospital, Clinical Oncology Department- , Tiblisi, Georgia","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071966445","display_name":"Emir Sokolovi\u0107","orcid":"https://orcid.org/0000-0001-7015-7378","observed_orcids":["https://orcid.org/0000-0001-7015-7378"]},"institutions":[{"id":"https://openalex.org/I4210110851","display_name":"Clinical Center University of Sarajevo","ror":"https://ror.org/019bz1656","country_code":"BA","type":"healthcare","lineage":["https://openalex.org/I4210110851"]}],"countries":["BA"],"is_corresponding":false,"raw_author_name":"E Sokolovic","raw_affiliation_strings":["Clinical Center University of Sarajevo, Clinic of Oncology , Sarajevo, Bosnia - Herzegovina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Center University of Sarajevo, Clinic of Oncology , Sarajevo, Bosnia - Herzegovina","institution_ids":["https://openalex.org/I4210110851"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109001354","display_name":"Gianfranco Scavone","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210146472","display_name":"Ospedale Policlinico San Martino","ror":"https://ror.org/04d7es448","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210146472","https://openalex.org/I4210153126","https://openalex.org/I4405264730"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"G Scavone","raw_affiliation_strings":["IRCCS San Martino Policlinic Hospital, Department of Medical Oncology- U.O.C. Clinica di Oncologia Medica , Genova, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"IRCCS San Martino Policlinic Hospital, Department of Medical Oncology- U.O.C. Clinica di Oncologia Medica , Genova, Italy","institution_ids":["https://openalex.org/I4210146472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076700690","display_name":"Selene Ottonello","orcid":"https://orcid.org/0000-0003-2635-2250","observed_orcids":["https://orcid.org/0000-0003-2635-2250"]},"institutions":[{"id":"https://openalex.org/I4210146472","display_name":"Ospedale Policlinico San Martino","ror":"https://ror.org/04d7es448","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210146472","https://openalex.org/I4210153126","https://openalex.org/I4405264730"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"S Ottonello","raw_affiliation_strings":["IRCCS San Martino Policlinic Hospital, Department of Medical Oncology- U.O.C. Clinica di Oncologia Medica , Genova, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"IRCCS San Martino Policlinic Hospital, Department of Medical Oncology- U.O.C. Clinica di Oncologia Medica , Genova, Italy","institution_ids":["https://openalex.org/I4210146472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101853056","display_name":"In\u00eas Vaz-Lu\u00eds","orcid":"https://orcid.org/0000-0002-7194-2260","observed_orcids":["https://orcid.org/0000-0002-7194-2260"]},"institutions":[{"id":"https://openalex.org/I2801843802","display_name":"Institut Gustave Roussy","ror":"https://ror.org/0321g0743","country_code":"FR","type":"facility","lineage":["https://openalex.org/I2801843802"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"I Vaz-Luis","raw_affiliation_strings":["Institut Gustave Roussy, Unit 981-Molecular Predictors and New Targets In Oncology- Department of Medical Oncology , Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut Gustave Roussy, Unit 981-Molecular Predictors and New Targets In Oncology- Department of Medical Oncology , Paris, France","institution_ids":["https://openalex.org/I2801843802"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082195410","display_name":"Cristina Saura","orcid":"https://orcid.org/0000-0001-8296-5065","observed_orcids":["https://orcid.org/0000-0001-8296-5065"]},"institutions":[{"id":"https://openalex.org/I4210127641","display_name":"Vall d'Hebron Hospital Universitari","ror":"https://ror.org/03ba28x55","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I157913058","https://openalex.org/I4210127641","https://openalex.org/I4210153292"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"C S\u00e0ura","raw_affiliation_strings":["Vall d\u2019Hebron University Hospital, Breast Cancer Unit- Medical Oncology Service , Barcelona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Vall d\u2019Hebron University Hospital, Breast Cancer Unit- Medical Oncology Service , Barcelona, Spain","institution_ids":["https://openalex.org/I4210127641"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028516152","display_name":"Richard A. Anderson","orcid":"https://orcid.org/0000-0002-7495-518X","observed_orcids":["https://orcid.org/0000-0002-7495-518X","https://orcid.org/0000-0001-6265-8359"]},"institutions":[{"id":"https://openalex.org/I4210116174","display_name":"MRC Centre for Reproductive Health","ror":"https://ror.org/02f4tsf92","country_code":"GB","type":"facility","lineage":["https://openalex.org/I4210087105","https://openalex.org/I4210116174","https://openalex.org/I90344618","https://openalex.org/I98677209"]},{"id":"https://openalex.org/I4210164624","display_name":"The Queen's Medical Research Institute","ror":"https://ror.org/059zxg644","country_code":"GB","type":"government","lineage":["https://openalex.org/I4210164624","https://openalex.org/I98677209"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"R A Anderson","raw_affiliation_strings":["The Queen's Medical Research Institute, MRC Centre for Reproductive Health , Edinburgh, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Queen's Medical Research Institute, MRC Centre for Reproductive Health , Edinburgh, United Kingdom","institution_ids":["https://openalex.org/I4210116174","https://openalex.org/I4210164624"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023088198","display_name":"Isabelle Demeestere","orcid":"https://orcid.org/0000-0002-3192-6565","observed_orcids":["https://orcid.org/0000-0002-3192-6565"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"I Demeestere","raw_affiliation_strings":["Fertility Clinic Erasme U.L.B., Research Laboratory on Human reproduction , Bruxelles, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fertility Clinic Erasme U.L.B., Research Laboratory on Human reproduction , Bruxelles, Belgium","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032252442","display_name":"Hatem A. Azim","orcid":"https://orcid.org/0000-0003-4865-3193","observed_orcids":["https://orcid.org/0000-0003-4865-3193"]},"institutions":[{"id":"https://openalex.org/I4210100904","display_name":"Hospital Zambrano Hellion","ror":"https://ror.org/011gp7f64","country_code":"MX","type":"healthcare","lineage":["https://openalex.org/I4210100904"]},{"id":"https://openalex.org/I98461037","display_name":"Tecnol\u00f3gico de Monterrey","ror":"https://ror.org/03ayjn504","country_code":"MX","type":"education","lineage":["https://openalex.org/I98461037"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"H A Azim","raw_affiliation_strings":["Hospital Zambrano Hellion- Tecnologico de Monterrey, Breast Cancer Center, San Pedro Garza Garcia , Mexico"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital Zambrano Hellion- Tecnologico de Monterrey, Breast Cancer Center, San Pedro Garza Garcia , Mexico","institution_ids":["https://openalex.org/I4210100904","https://openalex.org/I98461037"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007007404","display_name":"Fedro Alessandro Peccatori","orcid":"https://orcid.org/0000-0001-8227-8740","observed_orcids":["https://orcid.org/0000-0001-8227-8740"]},"institutions":[{"id":"https://openalex.org/I6141010","display_name":"European Institute of Oncology","ror":"https://ror.org/02vr0ne26","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126","https://openalex.org/I6141010"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"F A Peccatori","raw_affiliation_strings":["European Institute of Oncology, Fertility and Procreation Unit- Gynecologic Oncology Department , Milan, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"European Institute of Oncology, Fertility and Procreation Unit- Gynecologic Oncology Department , Milan, Italy","institution_ids":["https://openalex.org/I6141010"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039694693","display_name":"Ann H. Partridge","orcid":"https://orcid.org/0000-0002-4722-4824","observed_orcids":["https://orcid.org/0000-0002-4722-4824"]},"institutions":[{"id":"https://openalex.org/I4210117453","display_name":"Dana-Farber Cancer Institute","ror":"https://ror.org/02jzgtq86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210117453"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"A H Partridge","raw_affiliation_strings":["Dana-Farber Cancer Institute, Department of Medical Oncology , Boston, U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dana-Farber Cancer Institute, Department of Medical Oncology , Boston, U.S.A","institution_ids":["https://openalex.org/I4210117453"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5082293621","display_name":"Matteo Lambertini","orcid":"https://orcid.org/0000-0003-1797-5296","observed_orcids":["https://orcid.org/0000-0003-1797-5296"]},"institutions":[{"id":"https://openalex.org/I4210146472","display_name":"Ospedale Policlinico San Martino","ror":"https://ror.org/04d7es448","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210146472","https://openalex.org/I4210153126","https://openalex.org/I4405264730"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"M Lambertini","raw_affiliation_strings":["IRCCS San Martino Policlinic Hospital, Department of Medical Oncology- U.O.C. Clinica di Oncologia Medica , Genova, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"IRCCS San Martino Policlinic Hospital, Department of Medical Oncology- U.O.C. Clinica di Oncologia Medica , Genova, Italy","institution_ids":["https://openalex.org/I4210146472"]}]}],"institutions":[],"countries_distinct_count":7,"institutions_distinct_count":10,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3752,"currency":"EUR","value_usd":4059},"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"38","issue":"Supplement_1","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12103","display_name":"Cancer Risks and Factors","score":0.3659999966621399,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12103","display_name":"Cancer Risks and Factors","score":0.3659999966621399,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10183","display_name":"Breast Cancer Treatment Studies","score":0.28540000319480896,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10178","display_name":"Cancer survivorship and care","score":0.17870000004768372,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pregnancy-after-breast-cancer","display_name":"pregnancy after breast cancer","score":0.953000009059906},{"id":"https://openalex.org/keywords/hormone-receptor-positive-breast-cancer","display_name":"hormone receptor-positive breast cancer","score":0.9779999852180481},{"id":"https://openalex.org/keywords/early-breast-cancer","display_name":"early breast cancer","score":0.9580000042915344},{"id":"https://openalex.org/keywords/young-women","display_name":"young women","score":0.9419999718666077},{"id":"https://openalex.org/keywords/breast-cancer-survivors","display_name":"breast cancer survivors","score":0.8349999785423279},{"id":"https://openalex.org/keywords/disease-free-survival","display_name":"disease-free survival","score":0.8880000114440918},{"id":"https://openalex.org/keywords/overall-survival","display_name":"overall survival","score":1.0},{"id":"https://openalex.org/keywords/pregnancy-safety","display_name":"pregnancy safety","score":0.5070000290870667},{"id":"https://openalex.org/keywords/breast-cancer-recurrence","display_name":"breast cancer recurrence","score":0.4339999854564667},{"id":"https://openalex.org/keywords/endocrine-therapy","display_name":"endocrine therapy","score":0.4690000116825104}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.814719557762146},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.8011003136634827},{"id":"https://openalex.org/C207103383","wikidata":"https://www.wikidata.org/wiki/Q3930246","display_name":"Hazard ratio","level":3,"score":0.6446295976638794},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.5857017636299133},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.5189940333366394},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.5002737045288086},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4910886287689209},{"id":"https://openalex.org/C188816634","wikidata":"https://www.wikidata.org/wiki/Q2113324","display_name":"Prospective cohort study","level":2,"score":0.48428410291671753},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.4664302170276642},{"id":"https://openalex.org/C131872663","wikidata":"https://www.wikidata.org/wiki/Q5284418","display_name":"Obstetrics","level":1,"score":0.4347875118255615},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.19863009452819824},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1093/humrep/dead093.331","doi":"https://doi.org/10.1093/humrep/dead093.331","is_oa":true,"landing_page_url":"https://doi.org/10.1093/humrep/dead093.331","pdf_url":"https://academic.oup.com/humrep/article-pdf/38/Supplement_1/dead093.331/50786275/dead093.331.pdf","source":{"id":"https://openalex.org/S127900037","display_name":"Human Reproduction","issn_l":"0268-1161","issn":["0268-1161","1460-2350"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Human Reproduction","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1093/humrep/dead093.331","doi":"https://doi.org/10.1093/humrep/dead093.331","is_oa":true,"landing_page_url":"https://doi.org/10.1093/humrep/dead093.331","pdf_url":"https://academic.oup.com/humrep/article-pdf/38/Supplement_1/dead093.331/50786275/dead093.331.pdf","source":{"id":"https://openalex.org/S127900037","display_name":"Human Reproduction","issn_l":"0268-1161","issn":["0268-1161","1460-2350"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Human Reproduction","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4381892929.pdf","grobid_xml":"https://content.openalex.org/works/W4381892929.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4387889741","https://openalex.org/W4376613670","https://openalex.org/W7128684969","https://openalex.org/W7024387830","https://openalex.org/W4310941829","https://openalex.org/W7203875532","https://openalex.org/W1976688914","https://openalex.org/W1969384903","https://openalex.org/W2591519139","https://openalex.org/W2568256102"],"abstract_inverted_index":{"Abstract":[0],"Study":[1,107],"question":[2],"Is":[3],"it":[4],"safe":[5,38],"to":[6,68,128,218,256,296,412],"have":[7,69,94],"a":[8,72,185,238,282,320,348,361,399,415,472,509],"pregnancy":[9,77,99,162,283,322,349,362,385,401,417,438,489,510],"in":[10,28,58,82,103,224,259,275,341,389,433,471,493,511],"women":[11,30,59,183,512],"with":[12,31,39,121,160,184,206,237,268,317,347,358,435,513],"prior":[13,186,514],"history":[14,32,187,515],"of":[15,33,60,76,85,98,115,156,188,195,222,227,241,250,265,278,288,343,379,384,391,462,475,499,516],"hormone":[16,34,86,170,189,269,484,517],"receptor-positive":[17,35,87,171,190,270,518],"early":[18,191,437],"breast":[19,25,79,104,172,192,271,351,387,519],"cancer?":[20],"Summary":[21],"answer":[22],"Pregnancy":[23],"following":[24,134],"cancer":[26,51,105,272,352,388,520],"treatments":[27,102],"young":[29],"disease":[36],"is":[37,47,52,455,521],"no":[40,122,311,381],"detrimental":[41,74,382],"effect":[42,75,383],"on":[43,307,377,457],"patients\u2019":[44],"prognosis.":[45],"What":[46],"known":[48],"already":[49],"Breast":[50],"the":[53,83,96,135,220,225,228,248,260,289,374,463,476,500,505],"most":[54,461],"common":[55],"malignancy":[56],"diagnosed":[57],"reproductive":[61],"age.":[62],"Both":[63],"physicians":[64],"and":[65,118,144,167,200,247,460,487],"patients":[66,159,178,267,316,346,397,413,434],"continue":[67],"concerns":[70],"about":[71],"potential":[73,181],"after":[78,100,165,284,350,386,408,488],"cancer,":[80],"particularly":[81],"setting":[84],"disease.":[88],"In":[89,299],"recent":[90],"years,":[91],"several":[92],"studies":[93,146,253,291,301,334,464,477,495],"demonstrated":[95],"safety":[97],"anticancer":[101],"survivors.":[106],"design,":[108],"size,":[109],"duration":[110],"A":[111,263],"systematic":[112],"literature":[113],"search":[114],"Medline,":[116],"Embase":[117],"Cochrane":[119],"library":[120],"language":[123],"or":[124,141,163,318,405],"date":[125],"restriction":[126],"up":[127],"January":[129],"1st,":[130],"2023,":[131],"was":[132,216,313,394,431,478,490],"performed":[133],"PRISMA":[136],"guidelines.":[137],"We":[138],"included":[139,229,258,274,290],"retrospective":[140,466],"prospective":[142,150],"case-control":[143],"cohort":[145,467],"as":[147,149,403,410],"well":[148],"clinical":[151],"trials":[152],"comparing":[153],"survival":[154,199,309,356,393,430],"outcomes":[155,340],"premenopausal":[157],"female":[158],"reported":[161,339],"not":[164,491,526],"diagnosis":[166],"treatment":[168],"for":[169,396,451],"cancer.":[173,193],"Participants/materials,":[174],"setting,":[175],"methods":[176],"Included":[177],"were":[179,197,211,233,254,273],"childbearing":[180],"age":[182],"Outcomes":[194],"interest":[196],"disease-free":[198,308,392,429],"overall":[201,344,355],"survival.":[202],"Hazard":[203],"ratios":[204],"(HR)":[205],"95%":[207,325,365,420,441],"confidence":[208],"intervals":[209],"(CI)":[210],"extracted.":[212],"Higgins":[213],"I2":[214],"index":[215],"used":[217],"evaluate":[219],"degree":[221],"inconsistency":[223],"results":[226,246,503],"studies.":[230,468],"Pooled":[231],"HRs":[232],"considered":[234],"statistically":[235],"significant":[236],"P":[239],"value":[240],"<":[242,371,447],"0.05":[243],"(two-sided).":[244],"Main":[245],"role":[249],"chance":[251],"Eight":[252],"eligible":[255],"be":[257],"final":[261],"analysis.":[262],"total":[264],"3,805":[266],"these":[276],"studies,":[277],"whom":[279],"1,285":[280],"had":[281,353],"treatments.":[285],"Median":[286,469],"follow-up":[287,470],"ranged":[292],"from":[293],"3.81":[294],"years":[295,407],"15.8":[297],"years.":[298,482],"three":[300],"(n":[302,335],"=":[303,331,336,426],"987":[304],"patients)":[305,338],"reporting":[306],"outcomes,":[310],"difference":[312],"observed":[314,395,432],"between":[315],"without":[319,360,414],"subsequent":[321,416],"(HR":[323,363,418,439],"0.96,":[324],"CI":[326,366,421,442],"0.75":[327],"\u2013":[328,368,423,444],"1.24,":[329],"p":[330,370,425,446],"0.781).":[332],"Six":[333],"3,504":[337],"terms":[342,390],"survival:":[345],"better":[354],"compared":[357,411],"those":[359],"0.46,":[364],"0.27":[367],"0.77,":[369],"0.05).":[372,448],"At":[373],"subgroup":[375],"analysis":[376],"timing":[378],"pregnancy,":[380],"achieving":[398],"late":[400],"(defined":[402],"2":[404],"5":[406],"diagnosis)":[409],"1.08,":[419],"0.80":[422],"1.46,":[424],"0.611).":[427],"Increased":[428],"an":[436],"0.63,":[440],"0.47":[443],"0.85,":[445],"Limitations,":[449],"reasons":[450],"caution":[452],"This":[453],"meta-analysis":[454],"based":[456],"abstracted":[458],"data":[459],"are":[465],"large":[473],"proportion":[474],"shorter":[479],"than":[480],"10":[481],"Adjuvant":[483],"therapy":[485],"before":[486],"available":[492],"many":[494],"included.":[496],"Wider":[497],"implications":[498],"findings":[501],"Our":[502],"strengthen":[504],"evidence":[506],"that":[507],"having":[508],"safe.":[522],"Trial":[523],"registration":[524],"number":[525],"applicable":[527]},"counts_by_year":[],"updated_date":"2026-10-27T15:51:10.671819","created_date":"2023-06-25T00:00:00"}