{"id":"https://openalex.org/W4381661826","doi":"https://doi.org/10.3390/antiox12061307","title":"3-Bromo-4,5-dihydroxybenzaldehyde Protects Keratinocytes from Particulate Matter 2.5-Induced Damages","display_name":"3-Bromo-4,5-dihydroxybenzaldehyde Protects Keratinocytes from Particulate Matter 2.5-Induced Damages","publication_year":2023,"publication_date":"2023-06-20","ids":{"openalex":"https://openalex.org/W4381661826","doi":"https://doi.org/10.3390/antiox12061307","pmid":"https://pubmed.ncbi.nlm.nih.gov/37372037","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/10295767"},"language":"en","primary_location":{"id":"doi:10.3390/antiox12061307","doi":"https://doi.org/10.3390/antiox12061307","is_oa":true,"landing_page_url":"https://doi.org/10.3390/antiox12061307","pdf_url":"https://www.mdpi.com/2076-3921/12/6/1307/pdf?version=1687257635","source":{"id":"https://openalex.org/S2737566431","display_name":"Antioxidants","issn_l":"2076-3921","issn":["2076-3921"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Antioxidants","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/2076-3921/12/6/1307/pdf?version=1687257635","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5071128173","display_name":"Ao Xuan Zhen","orcid":"https://orcid.org/0000-0003-2689-093X","observed_orcids":["https://orcid.org/0000-0003-2689-093X"]},"institutions":[{"id":"https://openalex.org/I83202590","display_name":"Jeju National University","ror":"https://ror.org/05hnb4n85","country_code":"KR","type":"education","lineage":["https://openalex.org/I83202590"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Ao-Xuan Zhen","raw_affiliation_strings":["Department of Biochemistry, College of Medicine, Jeju National University, Jeju 63243, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, College of Medicine, Jeju National University, Jeju 63243, Republic of Korea","institution_ids":["https://openalex.org/I83202590"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086423452","display_name":"Mei-Jing Piao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I83202590","display_name":"Jeju National University","ror":"https://ror.org/05hnb4n85","country_code":"KR","type":"education","lineage":["https://openalex.org/I83202590"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Mei-Jing Piao","raw_affiliation_strings":["Jeju Research Center for Natural Medicine, Jeju National University, Jeju 63243, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Jeju Research Center for Natural Medicine, Jeju National University, Jeju 63243, Republic of Korea","institution_ids":["https://openalex.org/I83202590"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061062128","display_name":"Kyoung-Ah Kang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I83202590","display_name":"Jeju National University","ror":"https://ror.org/05hnb4n85","country_code":"KR","type":"education","lineage":["https://openalex.org/I83202590"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Kyoung-Ah Kang","raw_affiliation_strings":["Jeju Research Center for Natural Medicine, Jeju National University, Jeju 63243, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Jeju Research Center for Natural Medicine, Jeju National University, Jeju 63243, Republic of Korea","institution_ids":["https://openalex.org/I83202590"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002288537","display_name":"Pincha Devage Sameera Madushan Fernando","orcid":"https://orcid.org/0000-0002-8263-4706","observed_orcids":["https://orcid.org/0000-0002-8263-4706"]},"institutions":[{"id":"https://openalex.org/I83202590","display_name":"Jeju National University","ror":"https://ror.org/05hnb4n85","country_code":"KR","type":"education","lineage":["https://openalex.org/I83202590"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Pincha-Devage-Sameera-Madushan Fernando","raw_affiliation_strings":["Department of Biochemistry, College of Medicine, Jeju National University, Jeju 63243, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, College of Medicine, Jeju National University, Jeju 63243, Republic of Korea","institution_ids":["https://openalex.org/I83202590"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045351398","display_name":"Herath Mudiyanselage Udari Lakmini Herath","orcid":"https://orcid.org/0000-0002-6343-8697","observed_orcids":["https://orcid.org/0000-0002-6343-8697"]},"institutions":[{"id":"https://openalex.org/I83202590","display_name":"Jeju National University","ror":"https://ror.org/05hnb4n85","country_code":"KR","type":"education","lineage":["https://openalex.org/I83202590"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Herath-Mudiyanselage-Udari-Lakmini Herath","raw_affiliation_strings":["Department of Biochemistry, College of Medicine, Jeju National University, Jeju 63243, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, College of Medicine, Jeju National University, Jeju 63243, Republic of Korea","institution_ids":["https://openalex.org/I83202590"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072641059","display_name":"Suk-Ju Cho","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210165782","display_name":"Jeju National University Hospital","ror":"https://ror.org/05p64mb74","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I4210165782","https://openalex.org/I83202590"]},{"id":"https://openalex.org/I83202590","display_name":"Jeju National University","ror":"https://ror.org/05hnb4n85","country_code":"KR","type":"education","lineage":["https://openalex.org/I83202590"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Suk-Ju Cho","raw_affiliation_strings":["Department of Anesthesiology, Jeju National University Hospital, College of Medicine, Jeju National University, Jeju 63241, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anesthesiology, Jeju National University Hospital, College of Medicine, Jeju National University, Jeju 63241, Republic of Korea","institution_ids":["https://openalex.org/I4210165782","https://openalex.org/I83202590"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5014739246","display_name":"Jin Won Hyun","orcid":"https://orcid.org/0000-0002-3403-3762","observed_orcids":["https://orcid.org/0000-0002-3403-3762"]},"institutions":[{"id":"https://openalex.org/I83202590","display_name":"Jeju National University","ror":"https://ror.org/05hnb4n85","country_code":"KR","type":"education","lineage":["https://openalex.org/I83202590"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Jin-Won Hyun","raw_affiliation_strings":["Department of Biochemistry, College of Medicine, Jeju National University, Jeju 63243, Republic of Korea","Jeju Research Center for Natural Medicine, Jeju National University, Jeju 63243, Republic of Korea"],"raw_orcid":"https://orcid.org/0000-0002-3403-3762","affiliations":[{"raw_affiliation_string":"Department of Biochemistry, College of Medicine, Jeju National University, Jeju 63243, Republic of Korea","institution_ids":["https://openalex.org/I83202590"]},{"raw_affiliation_string":"Jeju Research Center for Natural Medicine, Jeju National University, Jeju 63243, Republic of Korea","institution_ids":["https://openalex.org/I83202590"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5014739246","https://openalex.org/A5072641059"],"corresponding_institution_ids":["https://openalex.org/I4210165782","https://openalex.org/I83202590"],"apc_list":{"value":2400,"currency":"CHF","value_usd":2669},"apc_paid":{"value":2400,"currency":"CHF","value_usd":2669},"fwci":3.4664,"has_fulltext":true,"cited_by_count":14,"citation_normalized_percentile":{"value":0.9241573,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":95,"max":99},"biblio":{"volume":"12","issue":"6","first_page":"1307","last_page":"1307"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11013","display_name":"Skin Protection and Aging","score":0.9883000254631042,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11013","display_name":"Skin Protection and Aging","score":0.9883000254631042,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11390","display_name":"Seaweed-derived Bioactive Compounds","score":0.002400000113993883,"subfield":{"id":"https://openalex.org/subfields/1104","display_name":"Aquatic Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10937","display_name":"Telomeres, Telomerase, and Senescence","score":0.0013000000035390258,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/particulate-matter-2-5","display_name":"particulate matter 2.5","score":0.8880000114440918},{"id":"https://openalex.org/keywords/pm2-5","display_name":"PM2.5","score":0.7940000295639038},{"id":"https://openalex.org/keywords/keratinocytes","display_name":"keratinocytes","score":0.9039999842643738},{"id":"https://openalex.org/keywords/cellular-senescence","display_name":"cellular senescence","score":0.8659999966621399},{"id":"https://openalex.org/keywords/skin-damage","display_name":"skin damage","score":0.7799999713897705},{"id":"https://openalex.org/keywords/reactive-oxygen-species","display_name":"reactive oxygen species","score":0.7409999966621399},{"id":"https://openalex.org/keywords/lipid-peroxidation","display_name":"lipid peroxidation","score":0.8529999852180481},{"id":"https://openalex.org/keywords/mitochondrial-dysfunction","display_name":"mitochondrial dysfunction","score":0.9789999723434448},{"id":"https://openalex.org/keywords/dna-damage","display_name":"DNA damage","score":0.9940000176429749},{"id":"https://openalex.org/keywords/apoptosis","display_name":"apoptosis","score":0.9459999799728394},{"id":"https://openalex.org/keywords/cell-cycle-arrest","display_name":"cell cycle arrest","score":0.9779999852180481},{"id":"https://openalex.org/keywords/inflammation","display_name":"inflammation","score":0.8019999861717224},{"id":"https://openalex.org/keywords/mapk-signaling","display_name":"MAPK signaling","score":0.7390000224113464},{"id":"https://openalex.org/keywords/ap-1","display_name":"AP-1","score":0.7409999966621399},{"id":"https://openalex.org/keywords/air-pollution","display_name":"air pollution","score":0.8019999861717224}],"concepts":[{"id":"https://openalex.org/C118995209","wikidata":"https://www.wikidata.org/wiki/Q5636366","display_name":"HaCaT","level":3,"score":0.827750563621521},{"id":"https://openalex.org/C143425029","wikidata":"https://www.wikidata.org/wiki/Q5205747","display_name":"DNA damage","level":3,"score":0.7281651496887207},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.6754159331321716},{"id":"https://openalex.org/C48349386","wikidata":"https://www.wikidata.org/wiki/Q424361","display_name":"Reactive oxygen species","level":2,"score":0.6518025994300842},{"id":"https://openalex.org/C190283241","wikidata":"https://www.wikidata.org/wiki/Q14599311","display_name":"Apoptosis","level":2,"score":0.6120538115501404},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.49812841415405273},{"id":"https://openalex.org/C2776151105","wikidata":"https://www.wikidata.org/wiki/Q898814","display_name":"Oxidative stress","level":2,"score":0.49182844161987305},{"id":"https://openalex.org/C2776960578","wikidata":"https://www.wikidata.org/wiki/Q3705873","display_name":"Photoaging","level":2,"score":0.4782918095588684},{"id":"https://openalex.org/C553184892","wikidata":"https://www.wikidata.org/wiki/Q1141429","display_name":"Flow cytometry","level":2,"score":0.47593334317207336},{"id":"https://openalex.org/C522857546","wikidata":"https://www.wikidata.org/wiki/Q2070979","display_name":"Senescence","level":2,"score":0.4433596432209015},{"id":"https://openalex.org/C2780829032","wikidata":"https://www.wikidata.org/wiki/Q898539","display_name":"Lipid peroxidation","level":3,"score":0.43589848279953003},{"id":"https://openalex.org/C29537977","wikidata":"https://www.wikidata.org/wiki/Q188941","display_name":"Cell cycle","level":3,"score":0.4283543527126312},{"id":"https://openalex.org/C2776415932","wikidata":"https://www.wikidata.org/wiki/Q48743","display_name":"Western blot","level":3,"score":0.4101366698741913},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.3335326910018921},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.33136945962905884},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.28655436635017395},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.28284555673599243},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.12365344166755676},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.3390/antiox12061307","doi":"https://doi.org/10.3390/antiox12061307","is_oa":true,"landing_page_url":"https://doi.org/10.3390/antiox12061307","pdf_url":"https://www.mdpi.com/2076-3921/12/6/1307/pdf?version=1687257635","source":{"id":"https://openalex.org/S2737566431","display_name":"Antioxidants","issn_l":"2076-3921","issn":["2076-3921"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Antioxidants","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:10295767","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10295767","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10295767/pdf/antioxidants-12-01307.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Antioxidants (Basel)","raw_type":"Text"},{"id":"pmid:37372037","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37372037","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Antioxidants (Basel, Switzerland)","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:bd3e7b772f054ec88929e80a4e8f31d4","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/bd3e7b772f054ec88929e80a4e8f31d4","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Antioxidants, Vol 12, Iss 6, p 1307 (2023)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3390/antiox12061307","doi":"https://doi.org/10.3390/antiox12061307","is_oa":true,"landing_page_url":"https://doi.org/10.3390/antiox12061307","pdf_url":"https://www.mdpi.com/2076-3921/12/6/1307/pdf?version=1687257635","source":{"id":"https://openalex.org/S2737566431","display_name":"Antioxidants","issn_l":"2076-3921","issn":["2076-3921"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Antioxidants","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9476000070571899,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320321191","display_name":"Jeju National University","ror":"https://ror.org/05hnb4n85"},{"id":"https://openalex.org/F4320324895","display_name":"Jeju National University Hospital","ror":"https://ror.org/05p64mb74"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4381661826.pdf","grobid_xml":"https://content.openalex.org/works/W4381661826.grobid-xml"},"referenced_works_count":53,"referenced_works":["https://openalex.org/W1963777621","https://openalex.org/W1976577998","https://openalex.org/W1988877971","https://openalex.org/W2010720463","https://openalex.org/W2015002324","https://openalex.org/W2039773944","https://openalex.org/W2267737556","https://openalex.org/W2308360335","https://openalex.org/W2565015133","https://openalex.org/W2605775809","https://openalex.org/W2745520872","https://openalex.org/W2754474991","https://openalex.org/W2761203100","https://openalex.org/W2771034038","https://openalex.org/W2781869685","https://openalex.org/W2788548733","https://openalex.org/W2789017146","https://openalex.org/W2791708939","https://openalex.org/W2792025613","https://openalex.org/W2799557680","https://openalex.org/W2806220860","https://openalex.org/W2807007486","https://openalex.org/W2808558546","https://openalex.org/W2811422199","https://openalex.org/W2891298226","https://openalex.org/W2900550733","https://openalex.org/W2901203448","https://openalex.org/W2904006811","https://openalex.org/W2908896570","https://openalex.org/W2913107439","https://openalex.org/W2937384805","https://openalex.org/W2938875627","https://openalex.org/W2948026453","https://openalex.org/W2948142691","https://openalex.org/W2951872997","https://openalex.org/W2961427932","https://openalex.org/W2964821748","https://openalex.org/W2971525886","https://openalex.org/W2976086758","https://openalex.org/W2980130056","https://openalex.org/W2982176244","https://openalex.org/W3013726226","https://openalex.org/W3096592448","https://openalex.org/W3146579363","https://openalex.org/W3158090478","https://openalex.org/W3173642217","https://openalex.org/W3215475567","https://openalex.org/W4214950984","https://openalex.org/W4284889683","https://openalex.org/W4288450790","https://openalex.org/W4294307535","https://openalex.org/W4296984704","https://openalex.org/W6752980119"],"related_works":["https://openalex.org/W4395663539","https://openalex.org/W2745520872","https://openalex.org/W2015002324","https://openalex.org/W4391581575","https://openalex.org/W4403154131","https://openalex.org/W4410213828","https://openalex.org/W2937384805","https://openalex.org/W4396745502","https://openalex.org/W4412890651","https://openalex.org/W4399392056"],"abstract_inverted_index":{"Cellular":[0],"senescence":[1,73,122],"can":[2],"be":[3],"activated":[4,139],"by":[5,140,144,152],"several":[6],"stimuli,":[7],"including":[8],"ultraviolet":[9],"radiation":[10],"and":[11,38,49,71,81,93,103,114,119,125,135],"air":[12],"pollutants.":[13],"This":[14],"study":[15,86],"aimed":[16],"to":[17],"evaluate":[18],"the":[19,109,129],"protective":[20],"effect":[21],"of":[22],"marine":[23],"algae":[24],"compound":[25],"3-bromo-4,5-dihydroxybenzaldehyde":[26],"(3-BDB)":[27],"on":[28],"particulate":[29],"matter":[30],"2.5":[31],"(PM2.5)-induced":[32],"skin":[33,149],"cell":[34,65,111],"damage":[35,150],"in":[36,39,123,126],"vitro":[37,124],"vivo.":[40,127],"The":[41,84],"human":[42],"HaCaT":[43],"keratinocyte":[44],"was":[45],"pre-treated":[46],"with":[47,51],"3-BDB":[48,96,107,147],"then":[50],"PM2.5.":[52,153],"PM2.5-induced":[53,98,110],"reactive":[54],"oxygen":[55],"species":[56],"(ROS)":[57],"generation,":[58,100],"lipid":[59],"peroxidation,":[60],"mitochondrial":[61],"dysfunction,":[62,102],"DNA":[63,90,104],"damage,":[64,91],"cycle":[66,112],"arrest,":[67],"apoptotic":[68],"protein":[69,131,137],"expression,":[70],"cellular":[72,117,121],"were":[74,142],"measured":[75],"using":[76],"confocal":[77],"microscopy,":[78],"flow":[79],"cytometry,":[80],"Western":[82],"blot.":[83],"present":[85],"exhibited":[87],"PM2.5-generated":[88],"ROS,":[89],"inflammation,":[92,118],"senescence.":[94],"However,":[95],"ameliorated":[97],"ROS":[99],"mitochondria":[101],"damage.":[105],"Furthermore,":[106],"reversed":[108],"arrest":[113],"apoptosis,":[115],"reduced":[116],"mitigated":[120],"Moreover,":[128],"mitogen-activated":[130],"kinase":[132],"signaling":[133],"pathway":[134],"activator":[136],"1":[138],"PM2.5":[141],"inhibited":[143],"3-BDB.":[145],"Thus,":[146],"suppressed":[148],"induced":[151]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":8}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2023-06-23T00:00:00"}