{"id":"https://openalex.org/W4381164580","doi":"https://doi.org/10.1016/j.revmed.2023.04.209","title":"Quand introduire la ciclosporine pour traiter une RCH aigu\u00eb s\u00e9v\u00e8re r\u00e9fractaire aux st\u00e9ro\u00efdes ?","display_name":"Quand introduire la ciclosporine pour traiter une RCH aigu\u00eb s\u00e9v\u00e8re r\u00e9fractaire aux st\u00e9ro\u00efdes ?","publication_year":2023,"publication_date":"2023-06-01","ids":{"openalex":"https://openalex.org/W4381164580","doi":"https://doi.org/10.1016/j.revmed.2023.04.209"},"language":"fr","primary_location":{"id":"doi:10.1016/j.revmed.2023.04.209","doi":"https://doi.org/10.1016/j.revmed.2023.04.209","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.revmed.2023.04.209","pdf_url":null,"source":{"id":"https://openalex.org/S86692366","display_name":"La Revue de M\u00e9decine Interne","issn_l":"0248-8663","issn":["0248-8663","1768-3122"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"La Revue de M\u00e9decine Interne","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5063232577","display_name":"O. Chatti","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"O. Chatti","raw_affiliation_strings":["Service de gastro-ent\u00e9rologie, Sahloul 3 Sousse, Sousse, Tunisie"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Service de gastro-ent\u00e9rologie, Sahloul 3 Sousse, Sousse, Tunisie","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5104323446","display_name":"E. Nour","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"E. Nour","raw_affiliation_strings":["Gastrologie, Sahloul, Sousse, Tunisie"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Gastrologie, Sahloul, Sousse, Tunisie","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088337778","display_name":"Aya Hammami","orcid":"https://orcid.org/0000-0002-1304-9183","observed_orcids":["https://orcid.org/0000-0002-1304-9183"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A. Hammami","raw_affiliation_strings":["H\u00e9patogastroent\u00e9rologie, route ceinture, Sousse, Tunisie"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"H\u00e9patogastroent\u00e9rologie, route ceinture, Sousse, Tunisie","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006225534","display_name":"W. Ben Ameur","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210148482","display_name":"H\u00f4pital Sahloul","ror":"https://ror.org/043z88g18","country_code":"TN","type":"healthcare","lineage":["https://openalex.org/I4210148482"]}],"countries":["TN"],"is_corresponding":false,"raw_author_name":"W. Ben Ameur","raw_affiliation_strings":["Gastro-ent\u00e9rologie, h\u00f4pital universitaire Sahloul (CHU Sahloul), Sousse, Tunisie"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Gastro-ent\u00e9rologie, h\u00f4pital universitaire Sahloul (CHU Sahloul), Sousse, Tunisie","institution_ids":["https://openalex.org/I4210148482"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108864492","display_name":"W Dahmani","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210148482","display_name":"H\u00f4pital Sahloul","ror":"https://ror.org/043z88g18","country_code":"TN","type":"healthcare","lineage":["https://openalex.org/I4210148482"]}],"countries":["TN"],"is_corresponding":false,"raw_author_name":"W. Dahmani","raw_affiliation_strings":["Gastro-ent\u00e9rologie, h\u00f4pital universitaire Sahloul (CHU Sahloul), Sousse, Tunisie"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Gastro-ent\u00e9rologie, h\u00f4pital universitaire Sahloul (CHU Sahloul), Sousse, Tunisie","institution_ids":["https://openalex.org/I4210148482"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041038116","display_name":"A. Brahem","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210148482","display_name":"H\u00f4pital Sahloul","ror":"https://ror.org/043z88g18","country_code":"TN","type":"healthcare","lineage":["https://openalex.org/I4210148482"]}],"countries":["TN"],"is_corresponding":false,"raw_author_name":"A. Brahem","raw_affiliation_strings":["H\u00e9patogastroent\u00e9rologie, CHU Sahloul, Hammam, Sousse, Tunisie"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"H\u00e9patogastroent\u00e9rologie, CHU Sahloul, Hammam, Sousse, Tunisie","institution_ids":["https://openalex.org/I4210148482"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103943317","display_name":"A. Salem","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210148482","display_name":"H\u00f4pital Sahloul","ror":"https://ror.org/043z88g18","country_code":"TN","type":"healthcare","lineage":["https://openalex.org/I4210148482"]}],"countries":["TN"],"is_corresponding":false,"raw_author_name":"A. Salem","raw_affiliation_strings":["Gastro-ent\u00e9rologie, Sahloul, Sousse, Tunisie"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Gastro-ent\u00e9rologie, Sahloul, Sousse, Tunisie","institution_ids":["https://openalex.org/I4210148482"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112232255","display_name":"B.S. Aida","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210148482","display_name":"H\u00f4pital Sahloul","ror":"https://ror.org/043z88g18","country_code":"TN","type":"healthcare","lineage":["https://openalex.org/I4210148482"]}],"countries":["TN"],"is_corresponding":false,"raw_author_name":"B.S. Aida","raw_affiliation_strings":["Gastro-ent\u00e9rologie, h\u00f4pital universitaire Sahloul (CHU Sahloul), Sousse, Tunisie"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Gastro-ent\u00e9rologie, h\u00f4pital universitaire Sahloul (CHU Sahloul), Sousse, Tunisie","institution_ids":["https://openalex.org/I4210148482"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090043646","display_name":"M. Ksiaa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210148482","display_name":"H\u00f4pital Sahloul","ror":"https://ror.org/043z88g18","country_code":"TN","type":"healthcare","lineage":["https://openalex.org/I4210148482"]}],"countries":["TN"],"is_corresponding":false,"raw_author_name":"M. Ksiaa","raw_affiliation_strings":["H\u00e9patogastroent\u00e9rologie, CHU Sahloul, Hammam, Sousse, Tunisie"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"H\u00e9patogastroent\u00e9rologie, CHU Sahloul, Hammam, Sousse, Tunisie","institution_ids":["https://openalex.org/I4210148482"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110353947","display_name":"H. Jaziri","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210148482","display_name":"H\u00f4pital Sahloul","ror":"https://ror.org/043z88g18","country_code":"TN","type":"healthcare","lineage":["https://openalex.org/I4210148482"]}],"countries":["TN"],"is_corresponding":false,"raw_author_name":"H. Jaziri","raw_affiliation_strings":["H\u00e9patogastroent\u00e9rologie, CHU Sahloul, Hammam, Sousse, Tunisie"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"H\u00e9patogastroent\u00e9rologie, CHU Sahloul, Hammam, Sousse, Tunisie","institution_ids":["https://openalex.org/I4210148482"]}]},{"author_position":"last","author":{"id":null,"display_name":"J. Ali","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210148482","display_name":"H\u00f4pital Sahloul","ror":"https://ror.org/043z88g18","country_code":"TN","type":"healthcare","lineage":["https://openalex.org/I4210148482"]}],"countries":["TN"],"is_corresponding":false,"raw_author_name":"J. Ali","raw_affiliation_strings":["Gastro-ent\u00e9rologie, h\u00f4pital universitaire Sahloul (CHU Sahloul), Sousse, Tunisie"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Gastro-ent\u00e9rologie, h\u00f4pital universitaire Sahloul (CHU Sahloul), Sousse, Tunisie","institution_ids":["https://openalex.org/I4210148482"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5063232577"],"corresponding_institution_ids":[],"apc_list":{"value":2300,"currency":"USD","value_usd":2300},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.14009892,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"44","issue":null,"first_page":"A237","last_page":"A237"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10134","display_name":"Inflammatory Bowel Disease","score":0.989300012588501,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10134","display_name":"Inflammatory Bowel Disease","score":0.989300012588501,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11194","display_name":"Ocular Diseases and Beh\u00e7et\u2019s Syndrome","score":0.0017000000225380063,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13569","display_name":"Microscopic Colitis","score":0.0010999999940395355,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cyclosporine","display_name":"cyclosporine","score":0.8989999890327454},{"id":"https://openalex.org/keywords/severe-ulcerative-colitis","display_name":"severe ulcerative colitis","score":0.7739999890327454},{"id":"https://openalex.org/keywords/steroid-refractory-colitis","display_name":"steroid-refractory colitis","score":0.8040000200271606},{"id":"https://openalex.org/keywords/azathioprine","display_name":"azathioprine","score":0.9290000200271606},{"id":"https://openalex.org/keywords/relapse","display_name":"relapse","score":0.6179999709129333},{"id":"https://openalex.org/keywords/anti-tnf-therapy","display_name":"anti-TNF therapy","score":0.925000011920929},{"id":"https://openalex.org/keywords/colectomy-avoidance","display_name":"colectomy avoidance","score":0.703000009059906},{"id":"https://openalex.org/keywords/long-term-treatment-outcomes","display_name":"long-term treatment outcomes","score":0.5899999737739563},{"id":"https://openalex.org/keywords/crohn-s-disease","display_name":"Crohn's disease","score":0.5569999814033508},{"id":"https://openalex.org/keywords/immunosuppressive-therapy","display_name":"immunosuppressive therapy","score":0.5429999828338623},{"id":"https://openalex.org/keywords/corticosteroid-refractory-disease","display_name":"corticosteroid-refractory disease","score":0.5680000185966492},{"id":"https://openalex.org/keywords/relapse-free-survival","display_name":"relapse-free survival","score":0.3310000002384186}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7043057680130005},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.6998866200447083}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.revmed.2023.04.209","doi":"https://doi.org/10.1016/j.revmed.2023.04.209","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.revmed.2023.04.209","pdf_url":null,"source":{"id":"https://openalex.org/S86692366","display_name":"La Revue de M\u00e9decine Interne","issn_l":"0248-8663","issn":["0248-8663","1768-3122"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"La Revue de M\u00e9decine Interne","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W7052958088","https://openalex.org/W2019136914","https://openalex.org/W102406377","https://openalex.org/W64335054","https://openalex.org/W1836273935","https://openalex.org/W2790937520","https://openalex.org/W2299507824","https://openalex.org/W1996133803","https://openalex.org/W7043101879","https://openalex.org/W4281570288"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-02T10:15:12.560889","created_date":"2023-06-20T00:00:00"}