{"id":"https://openalex.org/W4379879320","doi":"https://doi.org/10.7554/elife.80653.sa0","title":"Editor's evaluation: Identification of epigenetic modulators as determinants of nuclear size and shape","display_name":"Editor's evaluation: Identification of epigenetic modulators as determinants of nuclear size and shape","publication_year":2022,"publication_date":"2022-08-31","ids":{"openalex":"https://openalex.org/W4379879320","doi":"https://doi.org/10.7554/elife.80653.sa0"},"language":"en","primary_location":{"id":"doi:10.7554/elife.80653.sa0","doi":"https://doi.org/10.7554/elife.80653.sa0","is_oa":true,"landing_page_url":"http://dx.doi.org/10.7554/elife.80653.sa0","pdf_url":"https://elifesciences.org/download/aHR0cHM6Ly9jZG4uZWxpZmVzY2llbmNlcy5vcmcvYXJ0aWNsZXMvODA2NTMvZWxpZmUtODA2NTMtdjIucGRmP2Nhbm9uaWNhbFVyaT1odHRwczovL2VsaWZlc2NpZW5jZXMub3JnL2FydGljbGVzLzgwNjUz/elife-80653-v2.pdf?_hash=wf89fx8VErYTWxnFT3GdSJk%2BfwOM%2BoT0pRLAJq55q6M%3D","source":{"id":"https://openalex.org/S1336409049","display_name":"eLife","issn_l":"2050-084X","issn":["2050-084X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311710","host_organization_name":"eLife Sciences Publications Ltd","host_organization_lineage":["https://openalex.org/P4310311710"],"host_organization_lineage_names":["eLife Sciences Publications Ltd"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"peer-review"},"volume":null,"type":"peer-review","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://elifesciences.org/download/aHR0cHM6Ly9jZG4uZWxpZmVzY2llbmNlcy5vcmcvYXJ0aWNsZXMvODA2NTMvZWxpZmUtODA2NTMtdjIucGRmP2Nhbm9uaWNhbFVyaT1odHRwczovL2VsaWZlc2NpZW5jZXMub3JnL2FydGljbGVzLzgwNjUz/elife-80653-v2.pdf?_hash=wf89fx8VErYTWxnFT3GdSJk%2BfwOM%2BoT0pRLAJq55q6M%3D","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5079470535","display_name":"Megan C. King","orcid":"https://orcid.org/0000-0002-1688-2226","observed_orcids":["https://orcid.org/0000-0002-1688-2226"]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Megan C King","raw_affiliation_strings":["Yale School of Medicine"],"raw_orcid":"https://orcid.org/0000-0002-1688-2226","affiliations":[{"raw_affiliation_string":"Yale School of Medicine","institution_ids":["https://openalex.org/I32971472"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5079470535"],"corresponding_institution_ids":["https://openalex.org/I32971472"],"apc_list":{"value":3000,"currency":"USD","value_usd":2500},"apc_paid":{"value":3000,"currency":"USD","value_usd":2500},"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11841","display_name":"Nuclear Structure and Function","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11841","display_name":"Nuclear Structure and Function","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11650","display_name":"Skin and Cellular Biology Research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nuclear-morphology","display_name":"nuclear morphology","score":0.9330000281333923},{"id":"https://openalex.org/keywords/nuclear-size","display_name":"nuclear size","score":0.9459999799728394},{"id":"https://openalex.org/keywords/nuclear-shape","display_name":"nuclear shape","score":0.5740000009536743},{"id":"https://openalex.org/keywords/epigenetic-modifiers","display_name":"epigenetic regulators","score":0.8640000224113464},{"id":"https://openalex.org/keywords/lamin-a","display_name":"lamin A","score":0.8389999866485596},{"id":"https://openalex.org/keywords/histone-h3","display_name":"histone H3","score":0.9980000257492065},{"id":"https://openalex.org/keywords/histone-h3-3","display_name":"histone H3.3","score":0.9399999976158142},{"id":"https://openalex.org/keywords/h3k27-methylation","display_name":"H3K27 methylation","score":0.9319999814033508},{"id":"https://openalex.org/keywords/heterochromatin","display_name":"heterochromatin","score":0.8669999837875366},{"id":"https://openalex.org/keywords/nuclear-lamina","display_name":"nuclear lamina","score":0.8650000095367432},{"id":"https://openalex.org/keywords/nuclear-envelope","display_name":"nuclear envelope","score":0.8769999742507935},{"id":"https://openalex.org/keywords/chromatin-state","display_name":"chromatin state","score":0.75},{"id":"https://openalex.org/keywords/sirna-screen","display_name":"siRNA screen","score":0.8199999928474426},{"id":"https://openalex.org/keywords/aging","display_name":"aging","score":0.34599998593330383},{"id":"https://openalex.org/keywords/cancer","display_name":"cancer","score":0.9470000267028809}],"concepts":[{"id":"https://openalex.org/C41091548","wikidata":"https://www.wikidata.org/wiki/Q26939","display_name":"Epigenetics","level":3,"score":0.7687504291534424},{"id":"https://openalex.org/C116834253","wikidata":"https://www.wikidata.org/wiki/Q2039217","display_name":"Identification (biology)","level":2,"score":0.7117583155632019},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.6022555232048035},{"id":"https://openalex.org/C78458016","wikidata":"https://www.wikidata.org/wiki/Q840400","display_name":"Evolutionary biology","level":1,"score":0.4138333797454834},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.405638188123703},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.24513903260231018},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.14739879965782166},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.06257084012031555}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.7554/elife.80653.sa0","doi":"https://doi.org/10.7554/elife.80653.sa0","is_oa":true,"landing_page_url":"http://dx.doi.org/10.7554/elife.80653.sa0","pdf_url":"https://elifesciences.org/download/aHR0cHM6Ly9jZG4uZWxpZmVzY2llbmNlcy5vcmcvYXJ0aWNsZXMvODA2NTMvZWxpZmUtODA2NTMtdjIucGRmP2Nhbm9uaWNhbFVyaT1odHRwczovL2VsaWZlc2NpZW5jZXMub3JnL2FydGljbGVzLzgwNjUz/elife-80653-v2.pdf?_hash=wf89fx8VErYTWxnFT3GdSJk%2BfwOM%2BoT0pRLAJq55q6M%3D","source":{"id":"https://openalex.org/S1336409049","display_name":"eLife","issn_l":"2050-084X","issn":["2050-084X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311710","host_organization_name":"eLife Sciences Publications Ltd","host_organization_lineage":["https://openalex.org/P4310311710"],"host_organization_lineage_names":["eLife Sciences Publications Ltd"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"peer-review"}],"best_oa_location":{"id":"doi:10.7554/elife.80653.sa0","doi":"https://doi.org/10.7554/elife.80653.sa0","is_oa":true,"landing_page_url":"http://dx.doi.org/10.7554/elife.80653.sa0","pdf_url":"https://elifesciences.org/download/aHR0cHM6Ly9jZG4uZWxpZmVzY2llbmNlcy5vcmcvYXJ0aWNsZXMvODA2NTMvZWxpZmUtODA2NTMtdjIucGRmP2Nhbm9uaWNhbFVyaT1odHRwczovL2VsaWZlc2NpZW5jZXMub3JnL2FydGljbGVzLzgwNjUz/elife-80653-v2.pdf?_hash=wf89fx8VErYTWxnFT3GdSJk%2BfwOM%2BoT0pRLAJq55q6M%3D","source":{"id":"https://openalex.org/S1336409049","display_name":"eLife","issn_l":"2050-084X","issn":["2050-084X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311710","host_organization_name":"eLife Sciences Publications Ltd","host_organization_lineage":["https://openalex.org/P4310311710"],"host_organization_lineage_names":["eLife Sciences Publications Ltd"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"peer-review"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G1542379004","display_name":null,"funder_award_id":"P20-GM-103432","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G1839694055","display_name":null,"funder_award_id":"#1012152","funder_id":"https://openalex.org/F4320332299","funder_display_name":"National Institute of Food and Agriculture"},{"id":"https://openalex.org/G3233298984","display_name":null,"funder_award_id":"1012152","funder_id":"https://openalex.org/F4320306114","funder_display_name":"U.S. Department of Agriculture"},{"id":"https://openalex.org/G9000062985","display_name":null,"funder_award_id":"P20-GM-103432","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G9000884962","display_name":"Nuclear Architecture and Disease","funder_award_id":"ZIABC010309","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G9000908358","display_name":"Mechanisms of nuclear morphology regulation","funder_award_id":"R35GM134885","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320306114","display_name":"U.S. Department of Agriculture","ror":"https://ror.org/01na82s61"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320332299","display_name":"National Institute of Food and Agriculture","ror":"https://ror.org/05qx3fv49"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4379879320.pdf","grobid_xml":"https://content.openalex.org/works/W4379879320.grobid-xml"},"referenced_works_count":86,"referenced_works":["https://openalex.org/W1487741670","https://openalex.org/W1836834096","https://openalex.org/W1964281587","https://openalex.org/W1964551999","https://openalex.org/W1972094443","https://openalex.org/W1978257498","https://openalex.org/W1978908359","https://openalex.org/W1983533553","https://openalex.org/W1989303071","https://openalex.org/W1992900610","https://openalex.org/W1995586942","https://openalex.org/W2007210739","https://openalex.org/W2010399610","https://openalex.org/W2016013331","https://openalex.org/W2028643362","https://openalex.org/W2030085171","https://openalex.org/W2033097911","https://openalex.org/W2038385761","https://openalex.org/W2042883526","https://openalex.org/W2046067852","https://openalex.org/W2052011655","https://openalex.org/W2054793128","https://openalex.org/W2056155872","https://openalex.org/W2063990636","https://openalex.org/W2066012703","https://openalex.org/W2067940869","https://openalex.org/W2070210672","https://openalex.org/W2071681982","https://openalex.org/W2072810104","https://openalex.org/W2073750037","https://openalex.org/W2078768877","https://openalex.org/W2083032264","https://openalex.org/W2085219392","https://openalex.org/W2093716927","https://openalex.org/W2097005988","https://openalex.org/W2100249743","https://openalex.org/W2109338679","https://openalex.org/W2120010359","https://openalex.org/W2124633704","https://openalex.org/W2130229552","https://openalex.org/W2133467893","https://openalex.org/W2139303823","https://openalex.org/W2139990120","https://openalex.org/W2142488410","https://openalex.org/W2143185290","https://openalex.org/W2145033500","https://openalex.org/W2158233796","https://openalex.org/W2160224424","https://openalex.org/W2161807515","https://openalex.org/W2162424885","https://openalex.org/W2167558439","https://openalex.org/W2171402579","https://openalex.org/W2285849728","https://openalex.org/W2311193189","https://openalex.org/W2335986416","https://openalex.org/W2346509327","https://openalex.org/W2512365985","https://openalex.org/W2553252993","https://openalex.org/W2571383784","https://openalex.org/W2614262899","https://openalex.org/W2753802561","https://openalex.org/W2765510117","https://openalex.org/W2886939826","https://openalex.org/W2908103441","https://openalex.org/W2914401773","https://openalex.org/W2921084959","https://openalex.org/W2941166073","https://openalex.org/W2949691998","https://openalex.org/W2977830322","https://openalex.org/W3016295533","https://openalex.org/W3026834406","https://openalex.org/W3029566462","https://openalex.org/W3049268379","https://openalex.org/W3109333644","https://openalex.org/W3127014991","https://openalex.org/W3128059144","https://openalex.org/W3141304995","https://openalex.org/W3179766919","https://openalex.org/W3207407491","https://openalex.org/W3212478069","https://openalex.org/W3214702501","https://openalex.org/W4200438555","https://openalex.org/W4246740517","https://openalex.org/W4247425028","https://openalex.org/W4299564444","https://openalex.org/W4308834893"],"related_works":["https://openalex.org/W4377564825","https://openalex.org/W3016295533","https://openalex.org/W1972956034","https://openalex.org/W7083191826","https://openalex.org/W3111354163","https://openalex.org/W2335986416","https://openalex.org/W2765510117","https://openalex.org/W4412012868","https://openalex.org/W3214702501","https://openalex.org/W1965335659"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2023-06-09T00:00:00"}