{"id":"https://openalex.org/W4379538101","doi":"https://doi.org/10.1016/j.biosx.2023.100360","title":"Recent technological advances in lab-on-a-chip for bone remodeling","display_name":"Recent technological advances in lab-on-a-chip for bone remodeling","publication_year":2023,"publication_date":"2023-06-06","ids":{"openalex":"https://openalex.org/W4379538101","doi":"https://doi.org/10.1016/j.biosx.2023.100360"},"language":"en","primary_location":{"id":"doi:10.1016/j.biosx.2023.100360","doi":"https://doi.org/10.1016/j.biosx.2023.100360","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.biosx.2023.100360","pdf_url":null,"source":{"id":"https://openalex.org/S4210214496","display_name":"Biosensors and Bioelectronics X","issn_l":"2590-1370","issn":["2590-1370"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","poland-20"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biosensors and Bioelectronics: X","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1016/j.biosx.2023.100360","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100739688","display_name":"Seoyeon Kim","orcid":"https://orcid.org/0000-0003-2132-5245","observed_orcids":["https://orcid.org/0000-0003-2132-5245","https://orcid.org/0009-0008-7143-3715"]},"institutions":[{"id":"https://openalex.org/I139264467","display_name":"Seoul National University","ror":"https://ror.org/04h9pn542","country_code":"KR","type":"education","lineage":["https://openalex.org/I139264467"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Seoyeon Kim","raw_affiliation_strings":["School of Chemical and Biological Engineering, Institute of Chemical Processes, Seoul National University, Seoul 08826, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Chemical and Biological Engineering, Institute of Chemical Processes, Seoul National University, Seoul 08826, Republic of Korea","institution_ids":["https://openalex.org/I139264467"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035134532","display_name":"Arun Kumar Rajendran","orcid":"https://orcid.org/0000-0001-6443-6063","observed_orcids":["https://orcid.org/0000-0001-6443-6063"]},"institutions":[{"id":"https://openalex.org/I139264467","display_name":"Seoul National University","ror":"https://ror.org/04h9pn542","country_code":"KR","type":"education","lineage":["https://openalex.org/I139264467"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Arun Kumar Rajendran","raw_affiliation_strings":["Institute of Chemical Processes, Seoul National University, Seoul 08826, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Chemical Processes, Seoul National University, Seoul 08826, Republic of Korea","institution_ids":["https://openalex.org/I139264467"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020970207","display_name":"Sivashanmugam Amirthalingam","orcid":"https://orcid.org/0000-0002-0982-4634","observed_orcids":["https://orcid.org/0000-0002-0982-4634"]},"institutions":[{"id":"https://openalex.org/I139264467","display_name":"Seoul National University","ror":"https://ror.org/04h9pn542","country_code":"KR","type":"education","lineage":["https://openalex.org/I139264467"]},{"id":"https://openalex.org/I4405269631","display_name":"Institute of Engineering Research","ror":"https://ror.org/04scsat82","country_code":"KR","type":"facility","lineage":["https://openalex.org/I4405269631"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Sivashanmugam Amirthalingam","raw_affiliation_strings":["Institute of Engineering Research, Seoul National University, Seoul 08826, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Engineering Research, Seoul National University, Seoul 08826, Republic of Korea","institution_ids":["https://openalex.org/I139264467","https://openalex.org/I4405269631"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101798961","display_name":"Jung Hun Kim","orcid":"https://orcid.org/0000-0002-3897-9408","observed_orcids":["https://orcid.org/0000-0002-3897-9408"]},"institutions":[{"id":"https://openalex.org/I139264467","display_name":"Seoul National University","ror":"https://ror.org/04h9pn542","country_code":"KR","type":"education","lineage":["https://openalex.org/I139264467"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Jung Hun Kim","raw_affiliation_strings":["School of Chemical and Biological Engineering, Institute of Chemical Processes, Seoul National University, Seoul 08826, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Chemical and Biological Engineering, Institute of Chemical Processes, Seoul National University, Seoul 08826, Republic of Korea","institution_ids":["https://openalex.org/I139264467"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089986886","display_name":"Kyoung\u2010Ha So","orcid":"https://orcid.org/0000-0002-1461-0518","observed_orcids":["https://orcid.org/0000-0002-1461-0518"]},"institutions":[{"id":"https://openalex.org/I139264467","display_name":"Seoul National University","ror":"https://ror.org/04h9pn542","country_code":"KR","type":"education","lineage":["https://openalex.org/I139264467"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Kyoung-Ha So","raw_affiliation_strings":["Bio-MAX/N-Bio, Institute of Bioengineering, Seoul National University, Seoul 08826, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bio-MAX/N-Bio, Institute of Bioengineering, Seoul National University, Seoul 08826, Republic of Korea","institution_ids":["https://openalex.org/I139264467"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5075710060","display_name":"Nathaniel Suk-Yeon Hwang","orcid":"https://orcid.org/0000-0003-3735-7727","observed_orcids":["https://orcid.org/0000-0003-3735-7727"]},"institutions":[{"id":"https://openalex.org/I139264467","display_name":"Seoul National University","ror":"https://ror.org/04h9pn542","country_code":"KR","type":"education","lineage":["https://openalex.org/I139264467"]},{"id":"https://openalex.org/I4405269631","display_name":"Institute of Engineering Research","ror":"https://ror.org/04scsat82","country_code":"KR","type":"facility","lineage":["https://openalex.org/I4405269631"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Nathaniel S. Hwang","raw_affiliation_strings":["Bio-MAX/N-Bio, Institute of Bioengineering, Seoul National University, Seoul 08826, Republic of Korea","Institute of Chemical Processes, Seoul National University, Seoul 08826, Republic of Korea","Institute of Engineering Research, Seoul National University, Seoul 08826, Republic of Korea","Interdisciplinary Program in Bioengineering, Seoul National University, Seoul 08826, Republic of Korea","School of Chemical and Biological Engineering, Institute of Chemical Processes, Seoul National University, Seoul 08826, Republic of Korea"],"raw_orcid":"https://orcid.org/0000-0003-3735-7727","affiliations":[{"raw_affiliation_string":"Bio-MAX/N-Bio, Institute of Bioengineering, Seoul National University, Seoul 08826, Republic of Korea","institution_ids":["https://openalex.org/I139264467"]},{"raw_affiliation_string":"Institute of Chemical Processes, Seoul National University, Seoul 08826, Republic of Korea","institution_ids":["https://openalex.org/I139264467"]},{"raw_affiliation_string":"Institute of Engineering Research, Seoul National University, Seoul 08826, Republic of Korea","institution_ids":["https://openalex.org/I139264467","https://openalex.org/I4405269631"]},{"raw_affiliation_string":"Interdisciplinary Program in Bioengineering, Seoul National University, Seoul 08826, Republic of Korea","institution_ids":["https://openalex.org/I139264467"]},{"raw_affiliation_string":"School of Chemical and Biological Engineering, Institute of Chemical Processes, Seoul National University, Seoul 08826, Republic of Korea","institution_ids":["https://openalex.org/I139264467"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5075710060"],"corresponding_institution_ids":["https://openalex.org/I139264467","https://openalex.org/I4405269631"],"apc_list":{"value":1790,"currency":"USD","value_usd":1790},"apc_paid":{"value":1790,"currency":"USD","value_usd":1790},"fwci":0.4087,"has_fulltext":false,"cited_by_count":6,"citation_normalized_percentile":{"value":0.45496073,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":97},"biblio":{"volume":"14","issue":null,"first_page":"100360","last_page":"100360"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11190","display_name":"3D Printing in Biomedical Research","score":0.6381999850273132,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11190","display_name":"3D Printing in Biomedical Research","score":0.6381999850273132,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10412","display_name":"Microfluidic and Capillary Electrophoresis Applications","score":0.3237000107765198,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11255","display_name":"Microfluidic and Bio-sensing Technologies","score":0.016699999570846558,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/lab-on-a-chip","display_name":"lab-on-a-chip","score":0.9990000128746033},{"id":"https://openalex.org/keywords/bone-remodeling","display_name":"bone remodeling","score":0.9850000143051147},{"id":"https://openalex.org/keywords/microfluidic-cell-culture","display_name":"microfluidic cell culture","score":0.7799999713897705},{"id":"https://openalex.org/keywords/organoids","display_name":"organoids","score":0.5820000171661377},{"id":"https://openalex.org/keywords/biosensors","display_name":"biosensors","score":0.9629999995231628},{"id":"https://openalex.org/keywords/in-line-analysis","display_name":"in-line analysis","score":0.5379999876022339},{"id":"https://openalex.org/keywords/tissue-engineering","display_name":"tissue engineering","score":0.734000027179718},{"id":"https://openalex.org/keywords/integrated-circuit-design","display_name":"integrated circuit design","score":0.6650000214576721},{"id":"https://openalex.org/keywords/real-time-monitoring","display_name":"real-time monitoring","score":0.49300000071525574},{"id":"https://openalex.org/keywords/imaging-techniques","display_name":"imaging modalities","score":0.3630000054836273}],"concepts":[{"id":"https://openalex.org/C165932988","wikidata":"https://www.wikidata.org/wiki/Q7101746","display_name":"Organ-on-a-chip","level":3,"score":0.6538680791854858},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5960761308670044},{"id":"https://openalex.org/C8673954","wikidata":"https://www.wikidata.org/wiki/Q138845","display_name":"Microfluidics","level":2,"score":0.4969072639942169},{"id":"https://openalex.org/C138942068","wikidata":"https://www.wikidata.org/wiki/Q633261","display_name":"Lab-on-a-chip","level":3,"score":0.4466976523399353},{"id":"https://openalex.org/C183696295","wikidata":"https://www.wikidata.org/wiki/Q2487696","display_name":"Biochemical engineering","level":1,"score":0.34373921155929565},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.31192341446876526},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.20253005623817444},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.08449989557266235}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1016/j.biosx.2023.100360","doi":"https://doi.org/10.1016/j.biosx.2023.100360","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.biosx.2023.100360","pdf_url":null,"source":{"id":"https://openalex.org/S4210214496","display_name":"Biosensors and Bioelectronics X","issn_l":"2590-1370","issn":["2590-1370"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","poland-20"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biosensors and Bioelectronics: X","raw_type":"journal-article"},{"id":"pmh:oai:doaj.org/article:6a6e0261b84041ceba63d15a9a8d4da7","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/6a6e0261b84041ceba63d15a9a8d4da7","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Biosensors and Bioelectronics: X, Vol 14, Iss , Pp 100360- (2023)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1016/j.biosx.2023.100360","doi":"https://doi.org/10.1016/j.biosx.2023.100360","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.biosx.2023.100360","pdf_url":null,"source":{"id":"https://openalex.org/S4210214496","display_name":"Biosensors and Bioelectronics X","issn_l":"2590-1370","issn":["2590-1370"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","poland-20"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biosensors and Bioelectronics: X","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G1172472165","display_name":null,"funder_award_id":"NRF-2021K1A3A1A57086407","funder_id":"https://openalex.org/F4320321408","funder_display_name":"Ministry of Education"},{"id":"https://openalex.org/G1907333577","display_name":null,"funder_award_id":"NRF-2022R1I1A1A01072365","funder_id":"https://openalex.org/F4320321408","funder_display_name":"Ministry of Education"},{"id":"https://openalex.org/G5277473040","display_name":null,"funder_award_id":"NRF-2022M3A9B6082680","funder_id":"https://openalex.org/F4320321408","funder_display_name":"Ministry of Education"},{"id":"https://openalex.org/G6011857915","display_name":null,"funder_award_id":"NRF-2021R1A2C2008821","funder_id":"https://openalex.org/F4320321408","funder_display_name":"Ministry of Education"},{"id":"https://openalex.org/G6258209411","display_name":null,"funder_award_id":"NRF-2020H1D3A1A04081286","funder_id":"https://openalex.org/F4320321408","funder_display_name":"Ministry of Education"}],"funders":[{"id":"https://openalex.org/F4320321408","display_name":"Ministry of Education","ror":"https://ror.org/01p262204"},{"id":"https://openalex.org/F4320322120","display_name":"National Research Foundation of Korea","ror":"https://ror.org/013aysd81"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":182,"referenced_works":["https://openalex.org/W1511006020","https://openalex.org/W1534528753","https://openalex.org/W1818943734","https://openalex.org/W1964447273","https://openalex.org/W1970676313","https://openalex.org/W1973089587","https://openalex.org/W1975687263","https://openalex.org/W1979665070","https://openalex.org/W1980864741","https://openalex.org/W1988809254","https://openalex.org/W1994504773","https://openalex.org/W2002438963","https://openalex.org/W2003035047","https://openalex.org/W2003177189","https://openalex.org/W2005073389","https://openalex.org/W2006396343","https://openalex.org/W2013520568","https://openalex.org/W2014321486","https://openalex.org/W2014330506","https://openalex.org/W2016330743","https://openalex.org/W2016658962","https://openalex.org/W2024250498","https://openalex.org/W2025789062","https://openalex.org/W2027588555","https://openalex.org/W2028664820","https://openalex.org/W2029277927","https://openalex.org/W2042767306","https://openalex.org/W2047090204","https://openalex.org/W2050242709","https://openalex.org/W2059957363","https://openalex.org/W2063027243","https://openalex.org/W2067207051","https://openalex.org/W2074467813","https://openalex.org/W2076922024","https://openalex.org/W2079617528","https://openalex.org/W2081925150","https://openalex.org/W2086187432","https://openalex.org/W2091551811","https://openalex.org/W2105432265","https://openalex.org/W2105535336","https://openalex.org/W2106417989","https://openalex.org/W2111331204","https://openalex.org/W2116911631","https://openalex.org/W2124838743","https://openalex.org/W2125436483","https://openalex.org/W2126915639","https://openalex.org/W2133926606","https://openalex.org/W2134208433","https://openalex.org/W2139996507","https://openalex.org/W2147152130","https://openalex.org/W2151151867","https://openalex.org/W2152841960","https://openalex.org/W2154555351","https://openalex.org/W2160212351","https://openalex.org/W2161260662","https://openalex.org/W2165877783","https://openalex.org/W2172637528","https://openalex.org/W2180003376","https://openalex.org/W2192571848","https://openalex.org/W2213652914","https://openalex.org/W2236142945","https://openalex.org/W2273560121","https://openalex.org/W2306934036","https://openalex.org/W2320117782","https://openalex.org/W2327407167","https://openalex.org/W2343143301","https://openalex.org/W2359747920","https://openalex.org/W2464915778","https://openalex.org/W2471750032","https://openalex.org/W2511446702","https://openalex.org/W2519647494","https://openalex.org/W2554492400","https://openalex.org/W2588576744","https://openalex.org/W2593758551","https://openalex.org/W2594543620","https://openalex.org/W2594759203","https://openalex.org/W2603682730","https://openalex.org/W2608711007","https://openalex.org/W2613145696","https://openalex.org/W2621877040","https://openalex.org/W2626725994","https://openalex.org/W2744720587","https://openalex.org/W2752973615","https://openalex.org/W2753231520","https://openalex.org/W2759276314","https://openalex.org/W2760740379","https://openalex.org/W2765218320","https://openalex.org/W2766739097","https://openalex.org/W2768964688","https://openalex.org/W2781993338","https://openalex.org/W2783249617","https://openalex.org/W2783942928","https://openalex.org/W2789343580","https://openalex.org/W2790852710","https://openalex.org/W2791092360","https://openalex.org/W2792221286","https://openalex.org/W2796074158","https://openalex.org/W2802802359","https://openalex.org/W2804653411","https://openalex.org/W2809437635","https://openalex.org/W2810946842","https://openalex.org/W2886039792","https://openalex.org/W2888816033","https://openalex.org/W2891279083","https://openalex.org/W2892228744","https://openalex.org/W2892279894","https://openalex.org/W2897845597","https://openalex.org/W2906905739","https://openalex.org/W2910635389","https://openalex.org/W2920460225","https://openalex.org/W2920934338","https://openalex.org/W2928803385","https://openalex.org/W2930455027","https://openalex.org/W2938466645","https://openalex.org/W2943456337","https://openalex.org/W2945761627","https://openalex.org/W2951589169","https://openalex.org/W2952452496","https://openalex.org/W2952977804","https://openalex.org/W2954507214","https://openalex.org/W2954534735","https://openalex.org/W2980581402","https://openalex.org/W2984917546","https://openalex.org/W2990811783","https://openalex.org/W2994778858","https://openalex.org/W2995212110","https://openalex.org/W3000511359","https://openalex.org/W3002451359","https://openalex.org/W3002826985","https://openalex.org/W3014092941","https://openalex.org/W3026996735","https://openalex.org/W3033450620","https://openalex.org/W3033640788","https://openalex.org/W3044607496","https://openalex.org/W3081739146","https://openalex.org/W3084445065","https://openalex.org/W3084453857","https://openalex.org/W3089141631","https://openalex.org/W3095023411","https://openalex.org/W3096771109","https://openalex.org/W3111015203","https://openalex.org/W3112727516","https://openalex.org/W3113191033","https://openalex.org/W3117164351","https://openalex.org/W3121977863","https://openalex.org/W3122695957","https://openalex.org/W3124307090","https://openalex.org/W3125511811","https://openalex.org/W3128700297","https://openalex.org/W3130526945","https://openalex.org/W3132445146","https://openalex.org/W3140499432","https://openalex.org/W3157236342","https://openalex.org/W3159899614","https://openalex.org/W3162754667","https://openalex.org/W3167503613","https://openalex.org/W3168667198","https://openalex.org/W3181373498","https://openalex.org/W3184442439","https://openalex.org/W3196554366","https://openalex.org/W3213963490","https://openalex.org/W3215458383","https://openalex.org/W4200417398","https://openalex.org/W4200624793","https://openalex.org/W4205251913","https://openalex.org/W4206987333","https://openalex.org/W4210259501","https://openalex.org/W4211003460","https://openalex.org/W4212785156","https://openalex.org/W4214615177","https://openalex.org/W4220800374","https://openalex.org/W4220960872","https://openalex.org/W4247589372","https://openalex.org/W4256450049","https://openalex.org/W4280540675","https://openalex.org/W4281395051","https://openalex.org/W4281999480","https://openalex.org/W4283643066","https://openalex.org/W4283703236","https://openalex.org/W4292567051","https://openalex.org/W4293463318","https://openalex.org/W6743955527"],"related_works":["https://openalex.org/W4301851778","https://openalex.org/W2791092360","https://openalex.org/W7082996448","https://openalex.org/W4304945285","https://openalex.org/W3034878585","https://openalex.org/W3009421948","https://openalex.org/W3036075506","https://openalex.org/W2519508832","https://openalex.org/W4297498754","https://openalex.org/W7163167158"],"abstract_inverted_index":{"Lab-on-a-chip":[0],"(LOC)":[1],"is":[2],"a":[3,9,23,99,119],"three-dimensional":[4],"cell":[5,61],"culture":[6],"platform":[7,107],"with":[8,118],"microfluidic":[10],"flow":[11],"that":[12],"biomimics":[13],"the":[14,40,52,60,84,104,112],"physiological":[15],"system":[16,54],"of":[17,42,59,77,91,114,130,140],"various":[18,147],"organs.":[19,93],"LOC":[20,53,106],"emerged":[21],"as":[22,151],"future":[24],"replacement":[25],"technology":[26],"for":[27,111,154],"in":[28,33,39,65],"vitro":[29],"cell-based":[30],"models":[31],"and":[32,45,62,72,88,132],"vivo":[34],"animal":[35],"models,":[36],"gaining":[37],"popularity":[38],"field":[41],"physiology,":[43],"pharmacology,":[44],"biology.":[46],"Nowadays,":[47],"sensors":[48],"are":[49],"incorporated":[50],"into":[51,102],"to":[55,67,82,97,136],"monitor":[56],"real-time":[57],"parameters":[58,90],"its":[63],"microenvironment":[64],"response":[66],"biophysical":[68],"and/or":[69],"biochemical":[70],"stimuli":[71],"maturation.":[73],"A":[74],"considerable":[75],"amount":[76],"studies":[78],"has":[79],"been":[80],"conducted":[81],"detect":[83],"mechanical,":[85],"physical,":[86],"electrical,":[87],"metabolic":[89],"engineered":[92,141],"This":[94,143],"paper":[95],"aims":[96],"provide":[98],"comprehensive":[100],"insight":[101],"how":[103],"biosensor-implemented":[105],"can":[108],"be":[109],"utilized":[110],"analysis":[113,139],"tissue":[115],"recapitulating":[116],"systems":[117],"focus":[120],"on":[121],"bone":[122],"remodeling.":[123],"We":[124],"describe":[125],"chip":[126],"design,":[127],"basic":[128],"principles":[129],"sensors,":[131],"ongoing":[133],"recent":[134],"efforts":[135],"perform":[137],"in-line":[138],"organoids.":[142],"review":[144],"also":[145],"presents":[146],"imaging":[148],"techniques":[149],"used":[150],"analytical":[152],"tools":[153],"visualizing":[155],"LOC.":[156]},"counts_by_year":[{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2023-06-07T00:00:00"}