{"id":"https://openalex.org/W4379281132","doi":"https://doi.org/10.1200/jco.2023.41.16_suppl.e20523","title":"Clinical characteristics of patients with non-small cell lung cancer eligible for biology-guided radiotherapy.","display_name":"Clinical characteristics of patients with non-small cell lung cancer eligible for biology-guided radiotherapy.","publication_year":2023,"publication_date":"2023-06-01","ids":{"openalex":"https://openalex.org/W4379281132","doi":"https://doi.org/10.1200/jco.2023.41.16_suppl.e20523"},"language":"en","primary_location":{"id":"doi:10.1200/jco.2023.41.16_suppl.e20523","doi":"https://doi.org/10.1200/jco.2023.41.16_suppl.e20523","is_oa":false,"landing_page_url":"http://dx.doi.org/10.1200/jco.2023.41.16_suppl.e20523","pdf_url":null,"source":{"id":"https://openalex.org/S15137598","display_name":"Journal of Clinical Oncology","issn_l":"0732-183X","issn":["0732-183X","1527-7755"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Oncology","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5084311400","display_name":"Santiago Olaechea","orcid":"https://orcid.org/0000-0002-1686-6744","observed_orcids":["https://orcid.org/0000-0002-1686-6744"]},"institutions":[{"id":"https://openalex.org/I867280407","display_name":"The University of Texas Southwestern Medical Center","ror":"https://ror.org/05byvp690","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I867280407"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Santiago Olaechea","raw_affiliation_strings":["UT Southwestern Medical School, Dallas, TX"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UT Southwestern Medical School, Dallas, TX","institution_ids":["https://openalex.org/I867280407"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061427391","display_name":"Tidie Song","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I867280407","display_name":"The University of Texas Southwestern Medical Center","ror":"https://ror.org/05byvp690","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I867280407"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tidie Song","raw_affiliation_strings":["UT Southwestern Medical Center, Dallas, TX"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UT Southwestern Medical Center, Dallas, TX","institution_ids":["https://openalex.org/I867280407"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Linda Gilmore","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I867280407","display_name":"The University of Texas Southwestern Medical Center","ror":"https://ror.org/05byvp690","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I867280407"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Linda Gilmore","raw_affiliation_strings":["UT Southwestern Medical Center, Dallas, TX"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UT Southwestern Medical Center, Dallas, TX","institution_ids":["https://openalex.org/I867280407"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043142565","display_name":"Rodney Elwood Infante","orcid":"https://orcid.org/0000-0003-2605-822X","observed_orcids":["https://orcid.org/0000-0003-2605-822X"]},"institutions":[{"id":"https://openalex.org/I867280407","display_name":"The University of Texas Southwestern Medical Center","ror":"https://ror.org/05byvp690","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I867280407"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rodney E. Infante","raw_affiliation_strings":["UT Southwestern Medical Center, Dallas, TX"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UT Southwestern Medical Center, Dallas, TX","institution_ids":["https://openalex.org/I867280407"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037600867","display_name":"Kenneth D. Westover","orcid":"https://orcid.org/0000-0003-3653-5923","observed_orcids":["https://orcid.org/0000-0003-3653-5923"]},"institutions":[{"id":"https://openalex.org/I867280407","display_name":"The University of Texas Southwestern Medical Center","ror":"https://ror.org/05byvp690","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I867280407"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kenneth D. Westover","raw_affiliation_strings":["UT Southwestern, Dallas, TX"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UT Southwestern, Dallas, TX","institution_ids":["https://openalex.org/I867280407"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058433844","display_name":"Yuanyuan Zhang","orcid":"https://orcid.org/0000-0001-9230-7314","observed_orcids":["https://orcid.org/0000-0001-9230-7314"]},"institutions":[{"id":"https://openalex.org/I867280407","display_name":"The University of Texas Southwestern Medical Center","ror":"https://ror.org/05byvp690","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I867280407"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yuanyuan Zhang","raw_affiliation_strings":["UT Southwestern Medical Center, Dallas, TX"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UT Southwestern Medical Center, Dallas, TX","institution_ids":["https://openalex.org/I867280407"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078795100","display_name":"Neil Bipinchandra Desai","orcid":"https://orcid.org/0000-0002-6287-3427","observed_orcids":["https://orcid.org/0000-0002-6287-3427"]},"institutions":[{"id":"https://openalex.org/I867280407","display_name":"The University of Texas Southwestern Medical Center","ror":"https://ror.org/05byvp690","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I867280407"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Neil B. Desai","raw_affiliation_strings":["UT Southwestern Medical Center, Dallas, TX"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UT Southwestern Medical Center, Dallas, TX","institution_ids":["https://openalex.org/I867280407"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060464914","display_name":"Tu Dan","orcid":"https://orcid.org/0000-0003-1154-0507","observed_orcids":["https://orcid.org/0000-0003-1154-0507"]},"institutions":[{"id":"https://openalex.org/I867280407","display_name":"The University of Texas Southwestern Medical Center","ror":"https://ror.org/05byvp690","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I867280407"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tu Dan","raw_affiliation_strings":["UT Southwestern Medical Center, Dallas, TX"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UT Southwestern Medical Center, Dallas, TX","institution_ids":["https://openalex.org/I867280407"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068359755","display_name":"Robert D Timmerman","orcid":"https://orcid.org/0000-0003-2462-1007","observed_orcids":["https://orcid.org/0000-0003-2462-1007"]},"institutions":[{"id":"https://openalex.org/I867280407","display_name":"The University of Texas Southwestern Medical Center","ror":"https://ror.org/05byvp690","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I867280407"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert D. Timmerman","raw_affiliation_strings":["University of Texas Southwestern Medical Center - Radiation Oncology, Dallas, TX"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Texas Southwestern Medical Center - Radiation Oncology, Dallas, TX","institution_ids":["https://openalex.org/I867280407"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046079675","display_name":"Orhan K. \u00d6z","orcid":"https://orcid.org/0000-0002-5846-6829","observed_orcids":["https://orcid.org/0000-0002-5846-6829"]},"institutions":[{"id":"https://openalex.org/I867280407","display_name":"The University of Texas Southwestern Medical Center","ror":"https://ror.org/05byvp690","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I867280407"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Orhan K. Oz","raw_affiliation_strings":["University of Texas Southwestern Medical Center, Dallas, TX"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Texas Southwestern Medical Center, Dallas, TX","institution_ids":["https://openalex.org/I867280407"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025135477","display_name":"Puneeth Iyengar","orcid":"https://orcid.org/0000-0003-3740-7915","observed_orcids":["https://orcid.org/0000-0003-3740-7915"]},"institutions":[{"id":"https://openalex.org/I867280407","display_name":"The University of Texas Southwestern Medical Center","ror":"https://ror.org/05byvp690","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I867280407"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Puneeth Iyengar","raw_affiliation_strings":["University of Texas Southwestern Medical Center, Dallas, TX"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Texas Southwestern Medical Center, Dallas, TX","institution_ids":["https://openalex.org/I867280407"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5070180666","display_name":"Aur\u00e9lie Garant","orcid":"https://orcid.org/0000-0003-3835-0906","observed_orcids":["https://orcid.org/0000-0003-3835-0906"]},"institutions":[{"id":"https://openalex.org/I867280407","display_name":"The University of Texas Southwestern Medical Center","ror":"https://ror.org/05byvp690","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I867280407"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Aurelie Garant","raw_affiliation_strings":["University of Texas Southwestern Medical Center, Dallas, TX"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Texas Southwestern Medical Center, Dallas, TX","institution_ids":["https://openalex.org/I867280407"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I867280407"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"41","issue":"16_suppl","first_page":"e20523","last_page":"e20523"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10202","display_name":"Lung Cancer Diagnosis and Treatment","score":0.8521000146865845,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10202","display_name":"Lung Cancer Diagnosis and Treatment","score":0.8521000146865845,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10358","display_name":"Advanced Radiotherapy Techniques","score":0.1306000053882599,"subfield":{"id":"https://openalex.org/subfields/3108","display_name":"Radiation"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10522","display_name":"Medical Imaging Techniques and Applications","score":0.009600000455975533,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/biology-guided-radiotherapy","display_name":"biology-guided radiotherapy","score":0.9779999852180481},{"id":"https://openalex.org/keywords/non-small-cell-lung-cancer","display_name":"non-small cell lung cancer","score":0.9950000047683716},{"id":"https://openalex.org/keywords/18f-fdg-pet-ct","display_name":"18F-FDG PET/CT","score":0.8489999771118164},{"id":"https://openalex.org/keywords/standardized-uptake-value","display_name":"standardized uptake value","score":0.8700000047683716},{"id":"https://openalex.org/keywords/tumor-size","display_name":"tumor size","score":0.7279999852180481},{"id":"https://openalex.org/keywords/patient-eligibility","display_name":"patient eligibility","score":0.7310000061988831},{"id":"https://openalex.org/keywords/lung-cancer-histology","display_name":"lung cancer histology","score":0.6330000162124634},{"id":"https://openalex.org/keywords/lung-cancer-stage","display_name":"lung cancer stage","score":0.7009999752044678}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.919819176197052},{"id":"https://openalex.org/C509974204","wikidata":"https://www.wikidata.org/wiki/Q180507","display_name":"Radiation therapy","level":2,"score":0.6810480356216431},{"id":"https://openalex.org/C2776256026","wikidata":"https://www.wikidata.org/wiki/Q47912","display_name":"Lung cancer","level":2,"score":0.6749114394187927},{"id":"https://openalex.org/C2775842073","wikidata":"https://www.wikidata.org/wiki/Q208376","display_name":"Positron emission tomography","level":2,"score":0.5672208070755005},{"id":"https://openalex.org/C2781182431","wikidata":"https://www.wikidata.org/wiki/Q356033","display_name":"Adenocarcinoma","level":3,"score":0.549109160900116},{"id":"https://openalex.org/C199374082","wikidata":"https://www.wikidata.org/wiki/Q907080","display_name":"Standardized uptake value","level":3,"score":0.5313226580619812},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.5028490424156189},{"id":"https://openalex.org/C2776598537","wikidata":"https://www.wikidata.org/wiki/Q1812651","display_name":"Clinical Oncology","level":3,"score":0.5013136863708496},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.501018762588501},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.4572039246559143},{"id":"https://openalex.org/C167135981","wikidata":"https://www.wikidata.org/wiki/Q2146302","display_name":"Retrospective cohort study","level":2,"score":0.44012826681137085},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.27484869956970215},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.23880630731582642}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1200/jco.2023.41.16_suppl.e20523","doi":"https://doi.org/10.1200/jco.2023.41.16_suppl.e20523","is_oa":false,"landing_page_url":"http://dx.doi.org/10.1200/jco.2023.41.16_suppl.e20523","pdf_url":null,"source":{"id":"https://openalex.org/S15137598","display_name":"Journal of Clinical Oncology","issn_l":"0732-183X","issn":["0732-183X","1527-7755"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Oncology","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9922999739646912}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W3093532328","https://openalex.org/W4416141551","https://openalex.org/W1966522337","https://openalex.org/W2100724053","https://openalex.org/W7223142076","https://openalex.org/W2044665073","https://openalex.org/W4402906396","https://openalex.org/W1981490568","https://openalex.org/W2007161304","https://openalex.org/W2594211164"],"abstract_inverted_index":{"e20523":[0],"Background:":[1],"Biology-guided":[2],"radiotherapy":[3,8,19,145,234],"(BgRT)":[4],"is":[5,255],"a":[6,81,265],"novel":[7,144],"modality":[9,267],"that":[10],"uses":[11],"real-time":[12],"positron":[13],"emission":[14],"tomography":[15],"(PET)":[16],"to":[17,45,137],"guide":[18],"beamlets.":[20],"BgRT":[21,58,141],"recently":[22],"received":[23],"FDA":[24],"clearance":[25],"for":[26,34,57,140,153],"clinical":[27],"use":[28],"using":[29],"the":[30,35,86,149,182],"18F":[31],"FDG":[32,62],"radiotracer":[33,247],"treatment":[36,261,268],"of":[37,72,114,121,160,172,232,246,259],"tumors":[38,225],"in":[39,85,237,270],"lung":[40,49],"and":[41,78,90,101,126,130,166,177,189,197,207,214,250],"bone.":[42],"We":[43,66],"sought":[44],"identify":[46],"non-small":[47],"cell":[48],"cancer":[50],"(NSCLC)":[51],"patients":[52,74,151,184],"who":[53,185],"may":[54],"be":[55],"candidates":[56],"based":[59],"on":[60,142,162],"diagnostic":[61,163],"PET/CT":[63],"imaging.":[64],"Methods:":[65],"conducted":[67],"an":[68,96],"IRB-approved":[69],"retrospective":[70],"assessment":[71],"NSCLC":[73,239],"diagnosed":[75],"between":[76],"01/01/2006":[77],"12/31/2013":[79],"at":[80,173],"tertiary":[82],"care":[83],"center":[84],"United":[87],"States.":[88],"Patient":[89],"tumor":[91,128,158,170,251],"characteristics":[92,122],"were":[93,108,123],"verified":[94],"by":[95],"institutional":[97],"data":[98],"repository":[99],"team":[100],"through":[102],"electronic":[103],"medical":[104],"record":[105],"review.":[106],"Patients":[107],"excluded":[109],"from":[110],"analysis":[111],"when":[112],"documentation":[113],"clinical/":[115],"imaging":[116,165],"findings":[117],"was":[118,235],"insufficient.":[119],"Frequency":[120],"interpreted":[124],"with":[125,157,169,201,218,272],"without":[127],"diameter":[129],"maximum":[131],"standardized":[132],"uptake":[133,248],"value":[134],"(SUVMax)":[135],"parameters,":[136,191],"confirm":[138],"eligibility":[139],"this":[143,260],"device.":[146],"Results:":[147],"Of":[148,181],"686":[150],"eligible":[152],"analysis,":[154],"523":[155],"presented":[156,168,200,217],"SUVMax":[159,188],"\u22656":[161],"PET":[164],"360":[167],"diameters":[171],"least":[174],"2":[175],"cm":[176],"below":[178],"5":[179],"cm.":[180],"277":[183],"met":[186],"both":[187],"size":[190,252],"respectively,":[192],"75":[193],"(27.1%),":[194],"145":[195],"(52.3%),":[196],"57":[198],"(20.6%)":[199],"squamous,":[202],"adenocarcinoma,":[203],"or":[204,223,269],"other/unknown":[205],"histology,":[206],"77":[208],"(27.9%),":[209],"29":[210],"(10.5%),":[211],"92":[212],"(33.3%),":[213],"78":[215],"(28.3%)":[216],"stage":[219],"I,":[220],"II,":[221],"III,":[222],"IV":[224],"(AJCC":[226],"7th":[227],"edition).":[228],"Conclusions:":[229],"Theoretical":[230],"applicability":[231,258],"biology-guided":[233],"observed":[236],"our":[238],"patient":[240],"cohort.":[241],"Therefore,":[242],"despite":[243],"current":[244],"limitations":[245],"thresholds":[249],"restrictions,":[253],"there":[254],"broad":[256],"potential":[257],"modality,":[262],"either":[263],"as":[264],"single":[266],"conjunction":[271],"active":[273],"systemic":[274],"therapy.":[275],"[Table:":[276],"see":[277],"text]":[278]},"counts_by_year":[],"updated_date":"2026-09-29T14:09:16.559479","created_date":"2023-06-05T00:00:00"}