{"id":"https://openalex.org/W4378901165","doi":"https://doi.org/10.3389/fpls.2023.1203554","title":"Editorial: Advances in plastid biology and its applications, volume II","display_name":"Editorial: Advances in plastid biology and its applications, volume II","publication_year":2023,"publication_date":"2023-05-31","ids":{"openalex":"https://openalex.org/W4378901165","doi":"https://doi.org/10.3389/fpls.2023.1203554","pmid":"https://pubmed.ncbi.nlm.nih.gov/37324683","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/10266583"},"language":"en","primary_location":{"id":"doi:10.3389/fpls.2023.1203554","doi":"https://doi.org/10.3389/fpls.2023.1203554","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fpls.2023.1203554","pdf_url":"https://www.frontiersin.org/articles/10.3389/fpls.2023.1203554/pdf","source":{"id":"https://openalex.org/S2493613807","display_name":"Frontiers in Plant Science","issn_l":"1664-462X","issn":["1664-462X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Plant Science","raw_type":"journal-article"},"volume":null,"type":"editorial","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.frontiersin.org/articles/10.3389/fpls.2023.1203554/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5008471207","display_name":"Brent L. Nielsen","orcid":"https://orcid.org/0000-0001-6300-4816","observed_orcids":["https://orcid.org/0000-0001-6300-4816"]},"institutions":[{"id":"https://openalex.org/I100005738","display_name":"Brigham Young University","ror":"https://ror.org/047rhhm47","country_code":"US","type":"education","lineage":["https://openalex.org/I100005738"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Brent L. Nielsen","raw_affiliation_strings":["Microbiology & Molecular Biology, Brigham Young University, Provo, UT, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Microbiology & Molecular Biology, Brigham Young University, Provo, UT, United States","institution_ids":["https://openalex.org/I100005738"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5018554406","display_name":"Niaz Ahmad","orcid":"https://orcid.org/0000-0002-9391-2089","observed_orcids":["https://orcid.org/0000-0002-9391-2089"]},"institutions":[{"id":"https://openalex.org/I1308171952","display_name":"National Institute for Biotechnology and Genetic Engineering","ror":"https://ror.org/01bh91531","country_code":"PK","type":"education","lineage":["https://openalex.org/I1308171952"]},{"id":"https://openalex.org/I134276161","display_name":"Pakistan Institute of Engineering and Applied Sciences","ror":"https://ror.org/04d4mbk19","country_code":"PK","type":"education","lineage":["https://openalex.org/I134276161"]}],"countries":["PK"],"is_corresponding":false,"raw_author_name":"Niaz Ahmad","raw_affiliation_strings":["Agricultural Biotechnology Division, National Institute for Biotechnology and Genetic Engineering College (NIBGE-C), Pakistan Institute of Engineering and Applied Sciences (PIEAS), Faisalabad, Pakistan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Agricultural Biotechnology Division, National Institute for Biotechnology and Genetic Engineering College (NIBGE-C), Pakistan Institute of Engineering and Applied Sciences (PIEAS), Faisalabad, Pakistan","institution_ids":["https://openalex.org/I1308171952","https://openalex.org/I134276161"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5008471207"],"corresponding_institution_ids":["https://openalex.org/I100005738"],"apc_list":{"value":3295,"currency":"USD","value_usd":3295},"apc_paid":{"value":3295,"currency":"USD","value_usd":3295},"fwci":null,"has_fulltext":true,"cited_by_count":2,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"14","issue":null,"first_page":"1203554","last_page":"1203554"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12856","display_name":"Transgenic Plants and Applications","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1305","display_name":"Biotechnology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12856","display_name":"Transgenic Plants and Applications","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1305","display_name":"Biotechnology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10303","display_name":"Photosynthetic Processes and Mechanisms","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10240","display_name":"Plant tissue culture and regeneration","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chloroplast-transformation","display_name":"chloroplast transformation","score":0.8970000147819519},{"id":"https://openalex.org/keywords/plastid-transformation","display_name":"plastid transformation","score":0.6110000014305115},{"id":"https://openalex.org/keywords/recombinant-protein-expression","display_name":"recombinant protein expression","score":0.8009999990463257},{"id":"https://openalex.org/keywords/chloroplast-genome","display_name":"chloroplast genome","score":0.671999990940094},{"id":"https://openalex.org/keywords/homologous-recombination","display_name":"homologous recombination","score":0.843999981880188},{"id":"https://openalex.org/keywords/transgene-stability","display_name":"transgene stability","score":0.5429999828338623},{"id":"https://openalex.org/keywords/plastid-gene-expression","display_name":"chloroplast gene expression","score":0.5339999794960022}],"concepts":[{"id":"https://openalex.org/C93829228","wikidata":"https://www.wikidata.org/wiki/Q165963","display_name":"Plastid","level":4,"score":0.5462590456008911},{"id":"https://openalex.org/C20556612","wikidata":"https://www.wikidata.org/wiki/Q4469374","display_name":"Volume (thermodynamics)","level":2,"score":0.5067177414894104},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.43469610810279846},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.3697412610054016},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.33695971965789795},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.1974639594554901},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.09687107801437378},{"id":"https://openalex.org/C69305403","wikidata":"https://www.wikidata.org/wiki/Q47263","display_name":"Chloroplast","level":3,"score":0.07232528924942017},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.06325110793113708},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.3389/fpls.2023.1203554","doi":"https://doi.org/10.3389/fpls.2023.1203554","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fpls.2023.1203554","pdf_url":"https://www.frontiersin.org/articles/10.3389/fpls.2023.1203554/pdf","source":{"id":"https://openalex.org/S2493613807","display_name":"Frontiers in Plant Science","issn_l":"1664-462X","issn":["1664-462X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Plant Science","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:10266583","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10266583","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10266583/pdf/fpls-14-1203554.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Front Plant Sci","raw_type":"Text"},{"id":"pmid:37324683","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37324683","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in plant science","raw_type":"Editorial"},{"id":"pmh:oai:doaj.org/article:eb6b08aef10c431892585c0881199f9a","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/eb6b08aef10c431892585c0881199f9a","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Plant Science, Vol 14 (2023)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3389/fpls.2023.1203554","doi":"https://doi.org/10.3389/fpls.2023.1203554","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fpls.2023.1203554","pdf_url":"https://www.frontiersin.org/articles/10.3389/fpls.2023.1203554/pdf","source":{"id":"https://openalex.org/S2493613807","display_name":"Frontiers in Plant Science","issn_l":"1664-462X","issn":["1664-462X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Plant Science","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320309309","display_name":"Brigham Young University","ror":"https://ror.org/047rhhm47"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4378901165.pdf","grobid_xml":"https://content.openalex.org/works/W4378901165.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2231636217","https://openalex.org/W27599449","https://openalex.org/W1976431857","https://openalex.org/W1998635756","https://openalex.org/W104095575","https://openalex.org/W2593435730","https://openalex.org/W4381736666","https://openalex.org/W2923410251","https://openalex.org/W2131945764","https://openalex.org/W2541624208"],"abstract_inverted_index":{"Advances":[0],"in":[1,79,103,133,158,256,355],"plastid":[2,13,51,61,166,235,273,293,303,311],"biology":[3],"and":[4,18,62,174,214,218,227,245,262,275,288,308,320],"its":[5],"applications,":[6],"volume":[7],"IIWhile":[8],"much":[9],"is":[10,93,305],"known":[11,315],"about":[12],"function,":[14,345],"genomics,":[15],"gene":[16,72,118,153],"expression":[17,37,143],"DNA":[19,206,222,231,236,241],"replication,":[20],"many":[21,104,317],"open":[22,352],"questions":[23],"remain.One":[24],"active":[25],"area":[26],"of":[27,33,38,40,50,56,83,97,125,137,149,270,279,295,325],"research":[28],"has":[29,276],"been":[30,341],"the":[31,36,54,70,84,87,94,101,113,122,128,146,170,181,230,268,277,283,299,302],"use":[32],"plastids":[34,64,224],"for":[35,43,121,145,172,177,186,272,285,292,316],"proteins":[39],"value,":[41],"whether":[42],"therapeutic,":[44],"research,":[45],"or":[46,180],"other":[47,296,321],"purposes.The":[48],"advantages":[49],"transformation":[52,167,274,294],"include":[53],"presence":[55],"multiple":[57,63],"genome":[58,102,130,304,312,327],"copies":[59],"per":[60,65,77],"plant":[66,178,258,297],"cell,":[67],"which":[68],"multiplies":[69],"overall":[71],"copy":[73],"numbersometimes":[74],"reaching":[75],"10,000":[76],"cell":[78],"mesophyll":[80],"tissues.Site-specific":[81],"integration":[82],"transgene(s)":[85],"at":[86],"chosen":[88],"location":[89],"through":[90],"homologous":[91,238],"recombination":[92],"hallmark":[95],"feature":[96],"chloroplast":[98,129],"transformation.Being":[99],"non-nuclear,":[100],"angiosperms,":[105],"particularly":[106],"field":[107],"crops,":[108],"does":[109,155],"not":[110,156],"spread":[111],"with":[112],"pollen,":[114],"providing":[115],"a":[116,134,141,193,198,202,210,215,349],"natural":[117],"containment":[119],"system":[120],"transgenes.The":[123],"introduction":[124],"transgenes":[126],"into":[127,207,223,234],"often":[131],"results":[132],"high":[135],"level":[136],"expression,":[138],"making":[139],"it":[140],"viable":[142],"platform":[144],"cost-effective":[147],"production":[148],"recombinant":[150,221],"proteins.In":[151],"addition,":[152],"silencing":[154],"occur":[157],"plastids.However,":[159],"there":[160,347],"are":[161,314],"some":[162],"limitations":[163],"to":[164,169,183,204,267,331,344],"traditional":[165],"due":[168],"need":[171,182,284],"specialized":[173,286],"expensive":[175],"equipment":[176],"tissues":[179],"isolate":[184],"protoplasts":[185],"PEG-mediated":[187],"transformation.Odahara":[188],"et":[189],"al.":[190],"have":[191,251,340],"developed":[192],"novel":[194],"method":[195],"that":[196,229],"utilizes":[197],"fusion":[199],"peptide":[200,213,217],"as":[201,343],"carrier":[203],"deliver":[205],"plastids.They":[208],"coupled":[209],"polycationic":[211],"DNA-binding":[212],"plastid-targeting":[216],"successfully":[219,255],"delivered":[220],"via":[225],"nanoparticles":[226],"confirmed":[228],"was":[232,242],"integrated":[233,240],"by":[237],"recombination.The":[239],"stably":[243],"maintained":[244],"expressed":[246],"after":[247],"several":[248],"generations.The":[249],"authors":[250],"used":[252],"this":[253],"approach":[254,265],"three":[257],"species:":[259],"tobacco,":[260],"rice":[261],"kenaf.This":[263],"new":[264],"adds":[266],"repertoire":[269],"methods":[271],"advantage":[278],"being":[280],"simple":[281],"without":[282],"equipment,":[287],"may":[289],"be":[290],"useful":[291],"species.Unlike":[298],"nuclear":[300],"genome,":[301],"quite":[306],"small":[307],"highly":[309],"compact.Complete":[310],"sequences":[313,328],"plants,":[318],"algal":[319],"photosynthetic":[322],"organisms.The":[323],"availability":[324],"complete":[326],"allows":[329],"researchers":[330],"functionally":[332],"characterize":[333],"genes":[334,339],"more":[335],"effectively.Nearly":[336],"all":[337],"encoded":[338],"identified":[342],"but":[346],"remain":[348],"few":[350],"hypothetical":[351],"reading":[353],"Frontiers":[354],"Plant":[356],"Science":[357],"frontiersin.":[358]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1}],"updated_date":"2026-10-29T09:56:32.521200","created_date":"2023-06-01T00:00:00"}