{"id":"https://openalex.org/W4378574697","doi":"https://doi.org/10.36348/sjmps.2023.v09i05.004","title":"In vitro Hypoglycemic Effect and Antimicrobial Activity of Methanol Extract of Underutilized Leafy Vegetable (Ipomoea batatas leaf)","display_name":"In vitro Hypoglycemic Effect and Antimicrobial Activity of Methanol Extract of Underutilized Leafy Vegetable (Ipomoea batatas leaf)","publication_year":2023,"publication_date":"2023-05-13","ids":{"openalex":"https://openalex.org/W4378574697","doi":"https://doi.org/10.36348/sjmps.2023.v09i05.004"},"language":"en","primary_location":{"id":"doi:10.36348/sjmps.2023.v09i05.004","doi":"https://doi.org/10.36348/sjmps.2023.v09i05.004","is_oa":true,"landing_page_url":"https://doi.org/10.36348/sjmps.2023.v09i05.004","pdf_url":"https://doi.org/10.36348/sjmps.2023.v09i05.004","source":{"id":"https://openalex.org/S4210223883","display_name":"Saudi Journal of Medical and Pharmaceutical Sciences","issn_l":"2413-4910","issn":["2413-4910","2413-4929"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Saudi Journal of Medical and Pharmaceutical Sciences","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://doi.org/10.36348/sjmps.2023.v09i05.004","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5092037222","display_name":"Ndu-osuoji Ijeoma","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210126124","display_name":"Federal Polytechnic Nekede","ror":"https://ror.org/02nwh8244","country_code":"NG","type":"education","lineage":["https://openalex.org/I4210126124"]}],"countries":["NG"],"is_corresponding":false,"raw_author_name":"Ndu-osuoji Ijeoma","raw_affiliation_strings":["Department of Microbiology/Biochemistry, Federal Polytechnic Nekede, Owerri, Nigeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology/Biochemistry, Federal Polytechnic Nekede, Owerri, Nigeria","institution_ids":["https://openalex.org/I4210126124"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Ajah Obinna","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I98220444","display_name":"Michael Okpara University of Agriculture","ror":"https://ror.org/050850526","country_code":"NG","type":"education","lineage":["https://openalex.org/I98220444"]}],"countries":["NG"],"is_corresponding":false,"raw_author_name":"Ajah Obinna","raw_affiliation_strings":["Department of Biochemistry, Micheal Okpara University of Agriculture, Umudike, Umuahia, Nigeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, Micheal Okpara University of Agriculture, Umudike, Umuahia, Nigeria","institution_ids":["https://openalex.org/I98220444"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024524643","display_name":"Ikenna Elvis Nnaoma","orcid":"https://orcid.org/0000-0001-9785-0631","observed_orcids":["https://orcid.org/0000-0001-9785-0631"]},"institutions":[{"id":"https://openalex.org/I4210126124","display_name":"Federal Polytechnic Nekede","ror":"https://ror.org/02nwh8244","country_code":"NG","type":"education","lineage":["https://openalex.org/I4210126124"]}],"countries":["NG"],"is_corresponding":false,"raw_author_name":"Nnaoma Ikenna Elvis","raw_affiliation_strings":["Department of Pharmaceutical Technology, Federal Polytechnic Nekede, Owerri, Nigeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmaceutical Technology, Federal Polytechnic Nekede, Owerri, Nigeria","institution_ids":["https://openalex.org/I4210126124"]}]},{"author_position":"last","author":{"id":null,"display_name":"Enete Uchenna","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210126124","display_name":"Federal Polytechnic Nekede","ror":"https://ror.org/02nwh8244","country_code":"NG","type":"education","lineage":["https://openalex.org/I4210126124"]}],"countries":["NG"],"is_corresponding":false,"raw_author_name":"Enete Uchenna","raw_affiliation_strings":["Department of Chemistry/Biochemistry, Federal Polytechnic Nekede, Owerri, Nigeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry/Biochemistry, Federal Polytechnic Nekede, Owerri, Nigeria","institution_ids":["https://openalex.org/I4210126124"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.5199,"has_fulltext":true,"cited_by_count":3,"citation_normalized_percentile":{"value":0.62754494,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"9","issue":"05","first_page":"297","last_page":"302"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11140","display_name":"Natural Antidiabetic Agents Studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11140","display_name":"Natural Antidiabetic Agents Studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14521","display_name":"Medicinal Plant Research","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10839","display_name":"Pancreatic function and diabetes","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sweet-potato","display_name":"Ipomoea batatas","score":0.9890000224113464},{"id":"https://openalex.org/keywords/sweet-potato-leaf","display_name":"sweet potato leaf","score":0.9129999876022339},{"id":"https://openalex.org/keywords/hypoglycemic-activity","display_name":"hypoglycemic activity","score":0.8569999933242798},{"id":"https://openalex.org/keywords/antimicrobial-activity","display_name":"antimicrobial activity","score":0.7429999709129333},{"id":"https://openalex.org/keywords/alpha-glucosidase-inhibition","display_name":"\u03b1-glucosidase inhibition","score":0.9419999718666077},{"id":"https://openalex.org/keywords/alpha-amylase-inhibition","display_name":"\u03b1-amylase inhibition","score":1.0},{"id":"https://openalex.org/keywords/lipase-inhibition","display_name":"lipase inhibition","score":0.9990000128746033},{"id":"https://openalex.org/keywords/diabetes-mellitus","display_name":"diabetes mellitus","score":0.8960000276565552},{"id":"https://openalex.org/keywords/medicinal-plants","display_name":"medicinal plants","score":0.5630000233650208},{"id":"https://openalex.org/keywords/methanol-extract","display_name":"methanol extract","score":0.6840000152587891}],"concepts":[{"id":"https://openalex.org/C4937899","wikidata":"https://www.wikidata.org/wiki/Q68541106","display_name":"Antimicrobial","level":2,"score":0.753721296787262},{"id":"https://openalex.org/C2778728632","wikidata":"https://www.wikidata.org/wiki/Q161173","display_name":"Ipomoea","level":2,"score":0.6170297861099243},{"id":"https://openalex.org/C11636898","wikidata":"https://www.wikidata.org/wiki/Q390585","display_name":"Agar diffusion test","level":4,"score":0.5663628578186035},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5436763763427734},{"id":"https://openalex.org/C2779697368","wikidata":"https://www.wikidata.org/wiki/Q380967","display_name":"Lipase","level":3,"score":0.5108649134635925},{"id":"https://openalex.org/C2777832050","wikidata":"https://www.wikidata.org/wiki/Q2839456","display_name":"Alpha-glucosidase","level":3,"score":0.4474935531616211},{"id":"https://openalex.org/C173959671","wikidata":"https://www.wikidata.org/wiki/Q106951023","display_name":"Alpha-amylase","level":4,"score":0.4384108781814575},{"id":"https://openalex.org/C176947019","wikidata":"https://www.wikidata.org/wiki/Q597889","display_name":"Minimum inhibitory concentration","level":3,"score":0.4330872893333435},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.43292197585105896},{"id":"https://openalex.org/C170835558","wikidata":"https://www.wikidata.org/wiki/Q17153","display_name":"Amylase","level":3,"score":0.38282081484794617},{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.33933955430984497},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.32943493127822876},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2776097059249878},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2147674858570099},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.19680267572402954},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.12455898523330688},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C547475151","wikidata":"https://www.wikidata.org/wiki/Q25419","display_name":"Escherichia coli","level":3,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.36348/sjmps.2023.v09i05.004","doi":"https://doi.org/10.36348/sjmps.2023.v09i05.004","is_oa":true,"landing_page_url":"https://doi.org/10.36348/sjmps.2023.v09i05.004","pdf_url":"https://doi.org/10.36348/sjmps.2023.v09i05.004","source":{"id":"https://openalex.org/S4210223883","display_name":"Saudi Journal of Medical and Pharmaceutical Sciences","issn_l":"2413-4910","issn":["2413-4910","2413-4929"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Saudi Journal of Medical and Pharmaceutical Sciences","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.36348/sjmps.2023.v09i05.004","doi":"https://doi.org/10.36348/sjmps.2023.v09i05.004","is_oa":true,"landing_page_url":"https://doi.org/10.36348/sjmps.2023.v09i05.004","pdf_url":"https://doi.org/10.36348/sjmps.2023.v09i05.004","source":{"id":"https://openalex.org/S4210223883","display_name":"Saudi Journal of Medical and Pharmaceutical Sciences","issn_l":"2413-4910","issn":["2413-4910","2413-4929"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Saudi Journal of Medical and Pharmaceutical Sciences","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9537000060081482,"display_name":"Good health and well-being"},{"id":"https://metadata.un.org/sdg/2","score":0.40450000762939453,"display_name":"Zero hunger"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320309385","display_name":"Texas Emerging Technology Fund","ror":"https://ror.org/02yyzvz79"},{"id":"https://openalex.org/F4320325463","display_name":"Tertiary Education Trust Fund","ror":"https://ror.org/03p8jwd38"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4378574697.pdf","grobid_xml":"https://content.openalex.org/works/W4378574697.grobid-xml"},"referenced_works_count":13,"referenced_works":["https://openalex.org/W1971676204","https://openalex.org/W1985642510","https://openalex.org/W2013850509","https://openalex.org/W2124770832","https://openalex.org/W2183924703","https://openalex.org/W2185019634","https://openalex.org/W2287562319","https://openalex.org/W2579850315","https://openalex.org/W2984333122","https://openalex.org/W3023181650","https://openalex.org/W3033784036","https://openalex.org/W3215201947","https://openalex.org/W4253623596"],"related_works":["https://openalex.org/W1636294333","https://openalex.org/W2549871123","https://openalex.org/W7167725415","https://openalex.org/W4406121986","https://openalex.org/W2886300135","https://openalex.org/W2462902298","https://openalex.org/W2414515836","https://openalex.org/W2324351336","https://openalex.org/W4212990104","https://openalex.org/W3012623670"],"abstract_inverted_index":{"Diabetes":[0,20],"mellitus":[1],"is":[2],"a":[3,183],"chronic":[4],"condition":[5],"characterized":[6],"by":[7],"major":[8],"derangements":[9],"in":[10,15,33,60,140,203],"glucose":[11,156,169],"metabolism":[12],"and":[13,17,21,35,38,58,116,206,210],"abnormalities":[14],"fat":[16],"protein":[18],"metabolism.":[19],"infection":[22],"are":[23],"among":[24],"the":[25,32,59,85,141,145,155,204],"serious":[26],"health":[27],"challenges.":[28],"This":[29],"study":[30,194],"evaluated":[31],"vitro":[34,61],"hypoglycemic":[36,62],"effect":[37],"antimicrobial":[39,49,177],"properties":[40],"of":[41,44,84,113,123,144,149,154,180,185,208],"methanol":[42],"extract":[43,106,120,146],"Ipomoea":[45,197],"batatas":[46,198],"leaf.":[47],"The":[48,82,95,105,119,152,168,176,193],"activity":[50,63,72,125],"was":[51,64,136,162,173],"done":[52,65],"using":[53,66],"agar":[54],"disc":[55],"diffusion":[56,79,170],"methods":[57],"Alpha-Glucosidase":[67],"Inhibitory":[68],"activities":[69],"assay,":[70,73,77],"Lipase":[71],"Glucose":[74,78],"absorption":[75,157],"Capacity":[76],"retardation":[80,171],"Index.":[81],"result":[83,153],"percentage":[86,96,127],"alpha":[87,97,114,117],"glucosidase":[88,115],"inhibition":[89,99,112,122,128,148,186],"ranged":[90,100,188],"from":[91,101,130,189],"35.70":[92],"to":[93,103,132,160,164,191],"56.33%.":[94],"amylase":[98],"40.96":[102],"65.15%.":[104],"showed":[107,182,195],"significant":[108],"(p<0.05)":[109,138],"dose":[110,166],"dependent":[111],"amylase.":[118],"possess":[121],"lipase":[124,150],"with":[126],"ranging":[129],"72.35":[131],"81.57%.":[133],"Though":[134],"there":[135],"non-significant":[137],"difference":[139],"various":[142],"concentrations":[143],"on":[147],"activity.":[151],"capacity":[158],"(0.30":[159],"2.25)":[161],"observed":[163],"be":[165,201],"dependent.":[167,175],"index":[172],"time":[174],"susceptibility":[178],"screening":[179],"extracts":[181],"zone":[184],"that":[187,196],"2.70":[190],"15.73mm.":[192],"leaf":[199],"could":[200],"used":[202],"treatment":[205],"management":[207],"diabetes":[209],"infections.":[211]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2023-05-28T00:00:00"}