{"id":"https://openalex.org/W4378087019","doi":"https://doi.org/10.14336/ad.2023.0516","title":"Connecting the Dots: The Cerebral Lymphatic System as a Bridge Between the Central Nervous System and Peripheral System in Health and Disease","display_name":"Connecting the Dots: The Cerebral Lymphatic System as a Bridge Between the Central Nervous System and Peripheral System in Health and Disease","publication_year":2023,"publication_date":"2023-05-23","ids":{"openalex":"https://openalex.org/W4378087019","doi":"https://doi.org/10.14336/ad.2023.0516","pmid":"https://pubmed.ncbi.nlm.nih.gov/37307828","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/10796102"},"language":"en","primary_location":{"id":"doi:10.14336/ad.2023.0516","doi":"https://doi.org/10.14336/ad.2023.0516","is_oa":true,"landing_page_url":"https://doi.org/10.14336/ad.2023.0516","pdf_url":"https://www.aginganddisease.org/EN/PDF/10.14336/AD.2023.0516","source":{"id":"https://openalex.org/S2738790859","display_name":"Aging and Disease","issn_l":"2152-5250","issn":["2152-5250"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310316031","host_organization_name":"Buck Institute for Research on Aging","host_organization_lineage":["https://openalex.org/P4310316031"],"host_organization_lineage_names":["Buck Institute for Research on Aging"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Aging and disease","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.aginganddisease.org/EN/PDF/10.14336/AD.2023.0516","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Hongxiang Zhao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I117331123","display_name":"Weifang Medical University","ror":"https://ror.org/03tmp6662","country_code":"CN","type":"education","lineage":["https://openalex.org/I117331123"]},{"id":"https://openalex.org/I4210100830","display_name":"Shandong Tumor Hospital","ror":"https://ror.org/01413r497","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210100830"]},{"id":"https://openalex.org/I4210163399","display_name":"Shandong First Medical University","ror":"https://ror.org/05jb9pq57","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210163399"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hongxiang Zhao","raw_affiliation_strings":["Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, Shandong, China","Shandong Provincial Medicine and Health Key Laboratory of Clinical Anesthesia, School of Anesthesiology, Weifang Medical University, Weifang, China","School of Anesthesiology, Weifang Medical University, Weifang, China","Shandong Provincial Medicine and Health Key Laboratory of Clinical Anesthesia,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, Shandong, China","institution_ids":["https://openalex.org/I4210100830","https://openalex.org/I4210163399"]},{"raw_affiliation_string":"Shandong Provincial Medicine and Health Key Laboratory of Clinical Anesthesia, School of Anesthesiology, Weifang Medical University, Weifang, China","institution_ids":["https://openalex.org/I117331123"]},{"raw_affiliation_string":"School of Anesthesiology, Weifang Medical University, Weifang, China","institution_ids":["https://openalex.org/I117331123"]},{"raw_affiliation_string":"Shandong Provincial Medicine and Health Key Laboratory of Clinical Anesthesia,","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039427953","display_name":"Meiyan Sun","orcid":"https://orcid.org/0000-0002-3382-9363","observed_orcids":["https://orcid.org/0000-0002-3382-9363"]},"institutions":[{"id":"https://openalex.org/I117331123","display_name":"Weifang Medical University","ror":"https://ror.org/03tmp6662","country_code":"CN","type":"education","lineage":["https://openalex.org/I117331123"]},{"id":"https://openalex.org/I4210100830","display_name":"Shandong Tumor Hospital","ror":"https://ror.org/01413r497","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210100830"]},{"id":"https://openalex.org/I4210163399","display_name":"Shandong First Medical University","ror":"https://ror.org/05jb9pq57","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210163399"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Meiyan Sun","raw_affiliation_strings":["Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, Shandong, China","Shandong Provincial Medicine and Health Key Laboratory of Clinical Anesthesia, School of Anesthesiology, Weifang Medical University, Weifang, China","School of Anesthesiology, Weifang Medical University, Weifang, China","Shandong Provincial Medicine and Health Key Laboratory of Clinical Anesthesia,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, Shandong, China","institution_ids":["https://openalex.org/I4210100830","https://openalex.org/I4210163399"]},{"raw_affiliation_string":"Shandong Provincial Medicine and Health Key Laboratory of Clinical Anesthesia, School of Anesthesiology, Weifang Medical University, Weifang, China","institution_ids":["https://openalex.org/I117331123"]},{"raw_affiliation_string":"School of Anesthesiology, Weifang Medical University, Weifang, China","institution_ids":["https://openalex.org/I117331123"]},{"raw_affiliation_string":"Shandong Provincial Medicine and Health Key Laboratory of Clinical Anesthesia,","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100333640","display_name":"Yue Zhang","orcid":"https://orcid.org/0000-0001-6349-6849","observed_orcids":["https://orcid.org/0000-0001-6349-6849"]},"institutions":[{"id":"https://openalex.org/I117331123","display_name":"Weifang Medical University","ror":"https://ror.org/03tmp6662","country_code":"CN","type":"education","lineage":["https://openalex.org/I117331123"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yue Zhang","raw_affiliation_strings":["Shandong Provincial Medicine and Health Key Laboratory of Clinical Anesthesia, School of Anesthesiology, Weifang Medical University, Weifang, China","School of Anesthesiology, Weifang Medical University, Weifang, China","Shandong Provincial Medicine and Health Key Laboratory of Clinical Anesthesia,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shandong Provincial Medicine and Health Key Laboratory of Clinical Anesthesia, School of Anesthesiology, Weifang Medical University, Weifang, China","institution_ids":["https://openalex.org/I117331123"]},{"raw_affiliation_string":"School of Anesthesiology, Weifang Medical University, Weifang, China","institution_ids":["https://openalex.org/I117331123"]},{"raw_affiliation_string":"Shandong Provincial Medicine and Health Key Laboratory of Clinical Anesthesia,","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Wenwen Kong","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I117331123","display_name":"Weifang Medical University","ror":"https://ror.org/03tmp6662","country_code":"CN","type":"education","lineage":["https://openalex.org/I117331123"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wenwen Kong","raw_affiliation_strings":["Shandong Provincial Medicine and Health Key Laboratory of Clinical Anesthesia, School of Anesthesiology, Weifang Medical University, Weifang, China","School of Anesthesiology, Weifang Medical University, Weifang, China","Shandong Provincial Medicine and Health Key Laboratory of Clinical Anesthesia,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shandong Provincial Medicine and Health Key Laboratory of Clinical Anesthesia, School of Anesthesiology, Weifang Medical University, Weifang, China","institution_ids":["https://openalex.org/I117331123"]},{"raw_affiliation_string":"School of Anesthesiology, Weifang Medical University, Weifang, China","institution_ids":["https://openalex.org/I117331123"]},{"raw_affiliation_string":"Shandong Provincial Medicine and Health Key Laboratory of Clinical Anesthesia,","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Lulu Fan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I117331123","display_name":"Weifang Medical University","ror":"https://ror.org/03tmp6662","country_code":"CN","type":"education","lineage":["https://openalex.org/I117331123"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lulu Fan","raw_affiliation_strings":["Shandong Provincial Medicine and Health Key Laboratory of Clinical Anesthesia, School of Anesthesiology, Weifang Medical University, Weifang, China","School of Anesthesiology, Weifang Medical University, Weifang, China","Shandong Provincial Medicine and Health Key Laboratory of Clinical Anesthesia,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shandong Provincial Medicine and Health Key Laboratory of Clinical Anesthesia, School of Anesthesiology, Weifang Medical University, Weifang, China","institution_ids":["https://openalex.org/I117331123"]},{"raw_affiliation_string":"School of Anesthesiology, Weifang Medical University, Weifang, China","institution_ids":["https://openalex.org/I117331123"]},{"raw_affiliation_string":"Shandong Provincial Medicine and Health Key Laboratory of Clinical Anesthesia,","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103269383","display_name":"Kaifang Wang","orcid":"https://orcid.org/0000-0003-2237-7100","observed_orcids":["https://orcid.org/0000-0003-2237-7100"]},"institutions":[{"id":"https://openalex.org/I117331123","display_name":"Weifang Medical University","ror":"https://ror.org/03tmp6662","country_code":"CN","type":"education","lineage":["https://openalex.org/I117331123"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Kaifang Wang","raw_affiliation_strings":["Shandong Provincial Medicine and Health Key Laboratory of Clinical Anesthesia, School of Anesthesiology, Weifang Medical University, Weifang, China","School of Anesthesiology, Weifang Medical University, Weifang, China","Shandong Provincial Medicine and Health Key Laboratory of Clinical Anesthesia,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shandong Provincial Medicine and Health Key Laboratory of Clinical Anesthesia, School of Anesthesiology, Weifang Medical University, Weifang, China","institution_ids":["https://openalex.org/I117331123"]},{"raw_affiliation_string":"School of Anesthesiology, Weifang Medical University, Weifang, China","institution_ids":["https://openalex.org/I117331123"]},{"raw_affiliation_string":"Shandong Provincial Medicine and Health Key Laboratory of Clinical Anesthesia,","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031106663","display_name":"Qing Xu","orcid":"https://orcid.org/0000-0002-9680-7356","observed_orcids":["https://orcid.org/0000-0002-9680-7356"]},"institutions":[{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qing Xu","raw_affiliation_strings":["Department of Anesthesiology, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anesthesiology, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, China","institution_ids":["https://openalex.org/I76130692"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020220746","display_name":"Baiyan Chen","orcid":"https://orcid.org/0000-0002-9336-705X","observed_orcids":["https://orcid.org/0000-0002-9336-705X"]},"institutions":[{"id":"https://openalex.org/I117331123","display_name":"Weifang Medical University","ror":"https://ror.org/03tmp6662","country_code":"CN","type":"education","lineage":["https://openalex.org/I117331123"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Baiyan Chen","raw_affiliation_strings":["Shandong Provincial Medicine and Health Key Laboratory of Clinical Anesthesia, School of Anesthesiology, Weifang Medical University, Weifang, China","School of Anesthesiology, Weifang Medical University, Weifang, China","Shandong Provincial Medicine and Health Key Laboratory of Clinical Anesthesia,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shandong Provincial Medicine and Health Key Laboratory of Clinical Anesthesia, School of Anesthesiology, Weifang Medical University, Weifang, China","institution_ids":["https://openalex.org/I117331123"]},{"raw_affiliation_string":"School of Anesthesiology, Weifang Medical University, Weifang, China","institution_ids":["https://openalex.org/I117331123"]},{"raw_affiliation_string":"Shandong Provincial Medicine and Health Key Laboratory of Clinical Anesthesia,","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Jianxin Dong","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I117331123","display_name":"Weifang Medical University","ror":"https://ror.org/03tmp6662","country_code":"CN","type":"education","lineage":["https://openalex.org/I117331123"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jianxin Dong","raw_affiliation_strings":["Shandong Provincial Medicine and Health Key Laboratory of Clinical Anesthesia, School of Anesthesiology, Weifang Medical University, Weifang, China","School of Anesthesiology, Weifang Medical University, Weifang, China","Shandong Provincial Medicine and Health Key Laboratory of Clinical Anesthesia,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shandong Provincial Medicine and Health Key Laboratory of Clinical Anesthesia, School of Anesthesiology, Weifang Medical University, Weifang, China","institution_ids":["https://openalex.org/I117331123"]},{"raw_affiliation_string":"School of Anesthesiology, Weifang Medical University, Weifang, China","institution_ids":["https://openalex.org/I117331123"]},{"raw_affiliation_string":"Shandong Provincial Medicine and Health Key Laboratory of Clinical Anesthesia,","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103244909","display_name":"Yanan Shi","orcid":"https://orcid.org/0000-0003-0813-1147","observed_orcids":["https://orcid.org/0000-0003-0813-1147","https://orcid.org/0009-0009-9738-7072"]},"institutions":[{"id":"https://openalex.org/I117331123","display_name":"Weifang Medical University","ror":"https://ror.org/03tmp6662","country_code":"CN","type":"education","lineage":["https://openalex.org/I117331123"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yanan Shi","raw_affiliation_strings":["Shandong Provincial Medicine and Health Key Laboratory of Clinical Anesthesia, School of Anesthesiology, Weifang Medical University, Weifang, China","School of Anesthesiology, Weifang Medical University, Weifang, China","Shandong Provincial Medicine and Health Key Laboratory of Clinical Anesthesia,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shandong Provincial Medicine and Health Key Laboratory of Clinical Anesthesia, School of Anesthesiology, Weifang Medical University, Weifang, China","institution_ids":["https://openalex.org/I117331123"]},{"raw_affiliation_string":"School of Anesthesiology, Weifang Medical University, Weifang, China","institution_ids":["https://openalex.org/I117331123"]},{"raw_affiliation_string":"Shandong Provincial Medicine and Health Key Laboratory of Clinical Anesthesia,","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101888742","display_name":"Zhengyan Wang","orcid":"https://orcid.org/0009-0007-0462-2076","observed_orcids":["https://orcid.org/0009-0007-0462-2076"]},"institutions":[{"id":"https://openalex.org/I117331123","display_name":"Weifang Medical University","ror":"https://ror.org/03tmp6662","country_code":"CN","type":"education","lineage":["https://openalex.org/I117331123"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhengyan Wang","raw_affiliation_strings":["Shandong Provincial Medicine and Health Key Laboratory of Clinical Anesthesia, School of Anesthesiology, Weifang Medical University, Weifang, China","School of Anesthesiology, Weifang Medical University, Weifang, China","Shandong Provincial Medicine and Health Key Laboratory of Clinical Anesthesia,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shandong Provincial Medicine and Health Key Laboratory of Clinical Anesthesia, School of Anesthesiology, Weifang Medical University, Weifang, China","institution_ids":["https://openalex.org/I117331123"]},{"raw_affiliation_string":"School of Anesthesiology, Weifang Medical University, Weifang, China","institution_ids":["https://openalex.org/I117331123"]},{"raw_affiliation_string":"Shandong Provincial Medicine and Health Key Laboratory of Clinical Anesthesia,","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064577492","display_name":"Shiqi Wang","orcid":"https://orcid.org/0000-0001-7752-5620","observed_orcids":["https://orcid.org/0000-0001-7752-5620"]},"institutions":[{"id":"https://openalex.org/I117331123","display_name":"Weifang Medical University","ror":"https://ror.org/03tmp6662","country_code":"CN","type":"education","lineage":["https://openalex.org/I117331123"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"ShiQi Wang","raw_affiliation_strings":["Shandong Provincial Medicine and Health Key Laboratory of Clinical Anesthesia, School of Anesthesiology, Weifang Medical University, Weifang, China","School of Anesthesiology, Weifang Medical University, Weifang, China","Shandong Provincial Medicine and Health Key Laboratory of Clinical Anesthesia,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shandong Provincial Medicine and Health Key Laboratory of Clinical Anesthesia, School of Anesthesiology, Weifang Medical University, Weifang, China","institution_ids":["https://openalex.org/I117331123"]},{"raw_affiliation_string":"School of Anesthesiology, Weifang Medical University, Weifang, China","institution_ids":["https://openalex.org/I117331123"]},{"raw_affiliation_string":"Shandong Provincial Medicine and Health Key Laboratory of Clinical Anesthesia,","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003875786","display_name":"Xiaoli Zhuang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I183519381","display_name":"Capital Medical University","ror":"https://ror.org/013xs5b60","country_code":"CN","type":"education","lineage":["https://openalex.org/I183519381"]},{"id":"https://openalex.org/I4210119028","display_name":"Beijing Anzhen Hospital","ror":"https://ror.org/02h2j1586","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210119028"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaoli Zhuang","raw_affiliation_strings":["Department of Anesthesiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anesthesiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China","institution_ids":["https://openalex.org/I183519381","https://openalex.org/I4210119028"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Qi Li","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I4210097066","display_name":"Shanghai Ninth People's Hospital","ror":"https://ror.org/010826a91","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210097066"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qi Li","raw_affiliation_strings":["Department of Anesthesiology, Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anesthesiology, Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I4210097066"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013604165","display_name":"Feihong Lin","orcid":"https://orcid.org/0000-0001-5914-295X","observed_orcids":["https://orcid.org/0000-0001-5914-295X"]},"institutions":[{"id":"https://openalex.org/I116953780","display_name":"Tongji University","ror":"https://ror.org/03rc6as71","country_code":"CN","type":"education","lineage":["https://openalex.org/I116953780"]},{"id":"https://openalex.org/I4210127126","display_name":"Shanghai Pulmonary Hospital","ror":"https://ror.org/033nbnf69","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210127126"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Feihong Lin","raw_affiliation_strings":["Department of Anesthesiology, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anesthesiology, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, China","institution_ids":["https://openalex.org/I116953780","https://openalex.org/I4210127126"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068562966","display_name":"Xinyu Yao","orcid":"https://orcid.org/0000-0003-4554-5592","observed_orcids":["https://orcid.org/0000-0003-4554-5592"]},"institutions":[{"id":"https://openalex.org/I2801769982","display_name":"First Affiliated Hospital of Wenzhou Medical University","ror":"https://ror.org/03cyvdv85","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2801769982"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xinyu Yao","raw_affiliation_strings":["Department of Anesthesiology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anesthesiology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China","institution_ids":["https://openalex.org/I2801769982"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5118983634","display_name":"Wenbo Zhang","orcid":"https://orcid.org/0009-0006-1621-3918","observed_orcids":["https://orcid.org/0009-0006-1621-3918"]},"institutions":[{"id":"https://openalex.org/I4210113495","display_name":"Children's Hospital of Zhejiang University","ror":"https://ror.org/025fyfd20","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210113495"]},{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"WenBo Zhang","raw_affiliation_strings":["Department of Neurosurgery, The Children's Hospital of Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, China","Department of Neurosurgery, The Children's Hospital of Zhejiang University School of Medicine,","National Clinical Research Center for Child Health, Hangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosurgery, The Children's Hospital of Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, China","institution_ids":["https://openalex.org/I4210113495","https://openalex.org/I76130692"]},{"raw_affiliation_string":"Department of Neurosurgery, The Children's Hospital of Zhejiang University School of Medicine,","institution_ids":["https://openalex.org/I4210113495"]},{"raw_affiliation_string":"National Clinical Research Center for Child Health, Hangzhou, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Chang Kong","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210093484","display_name":"Tianjin Nankai Hospital","ror":"https://ror.org/00hq79z10","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210093484"]},{"id":"https://openalex.org/I5740404","display_name":"Tianjin Medical University","ror":"https://ror.org/02mh8wx89","country_code":"CN","type":"education","lineage":["https://openalex.org/I5740404"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chang Kong","raw_affiliation_strings":["Department of Anesthesiology and Critical Care Medicine, Tianjin Nankai Hospital, Tianjin Medical University, Tianjin, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anesthesiology and Critical Care Medicine, Tianjin Nankai Hospital, Tianjin Medical University, Tianjin, China","institution_ids":["https://openalex.org/I4210093484","https://openalex.org/I5740404"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100422027","display_name":"Rui Zhang","orcid":"https://orcid.org/0000-0002-2956-3910","observed_orcids":["https://orcid.org/0000-0002-2956-3910","https://orcid.org/0000-0002-0451-2375"]},"institutions":[{"id":"https://openalex.org/I117331123","display_name":"Weifang Medical University","ror":"https://ror.org/03tmp6662","country_code":"CN","type":"education","lineage":["https://openalex.org/I117331123"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Rui Zhang","raw_affiliation_strings":["Department of Anesthesiology, Affiliated Hospital of Weifang Medical University, Weifang, China","Shandong Provincial Medicine and Health Key Laboratory of Clinical Anesthesia, School of Anesthesiology, Weifang Medical University, Weifang, China","School of Anesthesiology, Weifang Medical University, Weifang, China","Shandong Provincial Medicine and Health Key Laboratory of Clinical Anesthesia,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anesthesiology, Affiliated Hospital of Weifang Medical University, Weifang, China","institution_ids":["https://openalex.org/I117331123"]},{"raw_affiliation_string":"Shandong Provincial Medicine and Health Key Laboratory of Clinical Anesthesia, School of Anesthesiology, Weifang Medical University, Weifang, China","institution_ids":["https://openalex.org/I117331123"]},{"raw_affiliation_string":"School of Anesthesiology, Weifang Medical University, Weifang, China","institution_ids":["https://openalex.org/I117331123"]},{"raw_affiliation_string":"Shandong Provincial Medicine and Health Key Laboratory of Clinical Anesthesia,","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040492090","display_name":"Dayun Feng","orcid":"https://orcid.org/0000-0002-3070-8355","observed_orcids":["https://orcid.org/0000-0002-3070-8355"]},"institutions":[{"id":"https://openalex.org/I4210154136","display_name":"Tang Du Hospital","ror":"https://ror.org/04yvdan45","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210154136"]},{"id":"https://openalex.org/I9916479","display_name":"Air Force Medical University","ror":"https://ror.org/00ms48f15","country_code":"CN","type":"education","lineage":["https://openalex.org/I9916479"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Dayun Feng","raw_affiliation_strings":["Department of neurosurgery, Tangdu hospital, Fourth Military Medical University, Xi'an, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of neurosurgery, Tangdu hospital, Fourth Military Medical University, Xi'an, China","institution_ids":["https://openalex.org/I4210154136","https://openalex.org/I9916479"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5043768971","display_name":"Xiaoyong Zhao","orcid":"https://orcid.org/0000-0002-8088-7451","observed_orcids":["https://orcid.org/0000-0002-8088-7451"]},"institutions":[{"id":"https://openalex.org/I117331123","display_name":"Weifang Medical University","ror":"https://ror.org/03tmp6662","country_code":"CN","type":"education","lineage":["https://openalex.org/I117331123"]},{"id":"https://openalex.org/I4210100830","display_name":"Shandong Tumor Hospital","ror":"https://ror.org/01413r497","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210100830"]},{"id":"https://openalex.org/I4210163399","display_name":"Shandong First Medical University","ror":"https://ror.org/05jb9pq57","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210163399"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Xiaoyong Zhao","raw_affiliation_strings":["Department of Anesthesiology, Affiliated Hospital of Weifang Medical University, Weifang, China","Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, Shandong, China","Shandong Provincial Medicine and Health Key Laboratory of Clinical Anesthesia, School of Anesthesiology, Weifang Medical University, Weifang, China","School of Anesthesiology, Weifang Medical University, Weifang, China","Shandong Provincial Medicine and Health Key Laboratory of Clinical Anesthesia,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anesthesiology, Affiliated Hospital of Weifang Medical University, Weifang, China","institution_ids":["https://openalex.org/I117331123"]},{"raw_affiliation_string":"Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, Shandong, China","institution_ids":["https://openalex.org/I4210100830","https://openalex.org/I4210163399"]},{"raw_affiliation_string":"Shandong Provincial Medicine and Health Key Laboratory of Clinical Anesthesia, School of Anesthesiology, Weifang Medical University, Weifang, China","institution_ids":["https://openalex.org/I117331123"]},{"raw_affiliation_string":"School of Anesthesiology, Weifang Medical University, Weifang, China","institution_ids":["https://openalex.org/I117331123"]},{"raw_affiliation_string":"Shandong Provincial Medicine and Health Key Laboratory of Clinical Anesthesia,","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":16,"corresponding_author_ids":["https://openalex.org/A5043768971"],"corresponding_institution_ids":["https://openalex.org/I117331123","https://openalex.org/I4210100830","https://openalex.org/I4210163399"],"apc_list":{"value":2000,"currency":"USD","value_usd":2000},"apc_paid":{"value":2000,"currency":"USD","value_usd":2000},"fwci":0.8816,"has_fulltext":true,"cited_by_count":23,"citation_normalized_percentile":{"value":0.68244448,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":99},"biblio":{"volume":"15","issue":"1","first_page":"115","last_page":"115"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11406","display_name":"Cerebrospinal fluid and hydrocephalus","score":0.98580002784729,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11406","display_name":"Cerebrospinal fluid and hydrocephalus","score":0.98580002784729,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11469","display_name":"Lymphatic System and Diseases","score":0.006500000134110451,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11872","display_name":"Barrier Structure and Function Studies","score":0.002400000113993883,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/glymphatic-system","display_name":"glymphatic system","score":0.9020000100135803},{"id":"https://openalex.org/keywords/central-nervous-system-homeostasis","display_name":"CNS homeostasis","score":0.9599999785423279},{"id":"https://openalex.org/keywords/central-peripheral-interaction","display_name":"central-peripheral interaction","score":0.6359999775886536},{"id":"https://openalex.org/keywords/gastrointestinal-diseases","display_name":"gastrointestinal diseases","score":0.6399999856948853},{"id":"https://openalex.org/keywords/liver-disease","display_name":"liver disease","score":0.9459999799728394},{"id":"https://openalex.org/keywords/kidney-disease","display_name":"kidney disease","score":0.9760000109672546},{"id":"https://openalex.org/keywords/neurodegenerative-diseases","display_name":"neurodegenerative diseases","score":0.5649999976158142},{"id":"https://openalex.org/keywords/therapeutic-target","display_name":"therapeutic target","score":0.33399999141693115}],"concepts":[{"id":"https://openalex.org/C181152851","wikidata":"https://www.wikidata.org/wiki/Q712604","display_name":"Lymphatic system","level":2,"score":0.8259193301200867},{"id":"https://openalex.org/C529278444","wikidata":"https://www.wikidata.org/wiki/Q47273","display_name":"Central nervous system","level":2,"score":0.6917043924331665},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6151784062385559},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.5268940925598145},{"id":"https://openalex.org/C545314008","wikidata":"https://www.wikidata.org/wiki/Q169953","display_name":"Peripheral nervous system","level":3,"score":0.49201247096061707},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.480035662651062},{"id":"https://openalex.org/C545706735","wikidata":"https://www.wikidata.org/wiki/Q9404","display_name":"Nervous system","level":2,"score":0.47054439783096313},{"id":"https://openalex.org/C46762472","wikidata":"https://www.wikidata.org/wiki/Q178648","display_name":"Peripheral","level":2,"score":0.46406373381614685},{"id":"https://openalex.org/C100776233","wikidata":"https://www.wikidata.org/wiki/Q2532492","display_name":"Bridge (graph theory)","level":2,"score":0.43444934487342834},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.3492238521575928},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.19961103796958923},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.19182056188583374},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.11028653383255005}],"mesh":[{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D002490","descriptor_name":"Central Nervous System","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006706","descriptor_name":"Homeostasis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008208","descriptor_name":"Lymphatic System","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.14336/ad.2023.0516","doi":"https://doi.org/10.14336/ad.2023.0516","is_oa":true,"landing_page_url":"https://doi.org/10.14336/ad.2023.0516","pdf_url":"https://www.aginganddisease.org/EN/PDF/10.14336/AD.2023.0516","source":{"id":"https://openalex.org/S2738790859","display_name":"Aging and Disease","issn_l":"2152-5250","issn":["2152-5250"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310316031","host_organization_name":"Buck Institute for Research on Aging","host_organization_lineage":["https://openalex.org/P4310316031"],"host_organization_lineage_names":["Buck Institute for Research on Aging"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Aging and disease","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:10796102","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10796102","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10796102/pdf/ad-15-1-115.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Aging Dis","raw_type":"Text"},{"id":"pmid:37307828","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37307828","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Aging and disease","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.14336/ad.2023.0516","doi":"https://doi.org/10.14336/ad.2023.0516","is_oa":true,"landing_page_url":"https://doi.org/10.14336/ad.2023.0516","pdf_url":"https://www.aginganddisease.org/EN/PDF/10.14336/AD.2023.0516","source":{"id":"https://openalex.org/S2738790859","display_name":"Aging and Disease","issn_l":"2152-5250","issn":["2152-5250"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310316031","host_organization_name":"Buck Institute for Research on Aging","host_organization_lineage":["https://openalex.org/P4310316031"],"host_organization_lineage_names":["Buck Institute for Research on Aging"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Aging and disease","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.8560000061988831,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G273590790","display_name":null,"funder_award_id":"2021YX028","funder_id":"https://openalex.org/F4320324174","funder_display_name":"Natural Science Foundation of Shandong Province"},{"id":"https://openalex.org/G5295487362","display_name":null,"funder_award_id":"2019WS605","funder_id":"https://openalex.org/F4320324174","funder_display_name":"Natural Science Foundation of Shandong Province"},{"id":"https://openalex.org/G6421971622","display_name":null,"funder_award_id":"ZR2016HP06","funder_id":"https://openalex.org/F4320324174","funder_display_name":"Natural Science Foundation of Shandong Province"},{"id":"https://openalex.org/G707666146","display_name":null,"funder_award_id":"X2021514","funder_id":"https://openalex.org/F4320324174","funder_display_name":"Natural Science Foundation of Shandong Province"},{"id":"https://openalex.org/G7665581542","display_name":null,"funder_award_id":"202104110334","funder_id":"https://openalex.org/F4320324174","funder_display_name":"Natural Science Foundation of Shandong Province"}],"funders":[{"id":"https://openalex.org/F4320324174","display_name":"Natural Science Foundation of Shandong Province","ror":null},{"id":"https://openalex.org/F4320324530","display_name":"Fourth Military Medical University","ror":"https://ror.org/00ms48f15"},{"id":"https://openalex.org/F4320326711","display_name":"Weifang Medical University","ror":"https://ror.org/03tmp6662"},{"id":"https://openalex.org/F4320328999","display_name":"Shandong First Medical University","ror":null},{"id":"https://openalex.org/F4320329000","display_name":"Shandong Academy of Medical Sciences","ror":"https://ror.org/05jb9pq57"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4378087019.pdf","grobid_xml":"https://content.openalex.org/works/W4378087019.grobid-xml"},"referenced_works_count":391,"referenced_works":["https://openalex.org/W90976876","https://openalex.org/W211905087","https://openalex.org/W803903676","https://openalex.org/W960051915","https://openalex.org/W1265793160","https://openalex.org/W1482426502","https://openalex.org/W1493986974","https://openalex.org/W1520029774","https://openalex.org/W1535419310","https://openalex.org/W1570971207","https://openalex.org/W1588685142","https://openalex.org/W1701739348","https://openalex.org/W1751766074","https://openalex.org/W1752743784","https://openalex.org/W1846679411","https://openalex.org/W1856465806","https://openalex.org/W1895139732","https://openalex.org/W1923535990","https://openalex.org/W1934417607","https://openalex.org/W1950515180","https://openalex.org/W1967823816","https://openalex.org/W1968105193","https://openalex.org/W1969144895","https://openalex.org/W1969541866","https://openalex.org/W1970875476","https://openalex.org/W1971415551","https://openalex.org/W1973638711","https://openalex.org/W1975219533","https://openalex.org/W1975682575","https://openalex.org/W1978751130","https://openalex.org/W1987644452","https://openalex.org/W1993212770","https://openalex.org/W1994183414","https://openalex.org/W1996139782","https://openalex.org/W1996640792","https://openalex.org/W1997822484","https://openalex.org/W2001613505","https://openalex.org/W2003555906","https://openalex.org/W2004441324","https://openalex.org/W2008785905","https://openalex.org/W2010055058","https://openalex.org/W2016484007","https://openalex.org/W2017818722","https://openalex.org/W2018356836","https://openalex.org/W2018652973","https://openalex.org/W2021493191","https://openalex.org/W2022519719","https://openalex.org/W2023312657","https://openalex.org/W2024285581","https://openalex.org/W2024955728","https://openalex.org/W2025931764","https://openalex.org/W2026275665","https://openalex.org/W2028084402","https://openalex.org/W2028238072","https://openalex.org/W2028537535","https://openalex.org/W2029206809","https://openalex.org/W2030235211","https://openalex.org/W2030667631","https://openalex.org/W2034495888","https://openalex.org/W2037931437","https://openalex.org/W2037965956","https://openalex.org/W2042433863","https://openalex.org/W2042601182","https://openalex.org/W2042683896","https://openalex.org/W2048027697","https://openalex.org/W2048259921","https://openalex.org/W2051117131","https://openalex.org/W2053405269","https://openalex.org/W2058690468","https://openalex.org/W2061257207","https://openalex.org/W2062073560","https://openalex.org/W2065372694","https://openalex.org/W2068568996","https://openalex.org/W2068791334","https://openalex.org/W2069802074","https://openalex.org/W2070996506","https://openalex.org/W2076941421","https://openalex.org/W2080418767","https://openalex.org/W2083479642","https://openalex.org/W2085175109","https://openalex.org/W2089176022","https://openalex.org/W2090592195","https://openalex.org/W2093050951","https://openalex.org/W2094785614","https://openalex.org/W2097700658","https://openalex.org/W2097731330","https://openalex.org/W2098259366","https://openalex.org/W2098722533","https://openalex.org/W2099703857","https://openalex.org/W2100314515","https://openalex.org/W2100676445","https://openalex.org/W2103307831","https://openalex.org/W2105207470","https://openalex.org/W2105528790","https://openalex.org/W2105932465","https://openalex.org/W2105986361","https://openalex.org/W2109618496","https://openalex.org/W2109727228","https://openalex.org/W2110729320","https://openalex.org/W2113215822","https://openalex.org/W2116141324","https://openalex.org/W2118403357","https://openalex.org/W2120802597","https://openalex.org/W2120987567","https://openalex.org/W2127716652","https://openalex.org/W2129514158","https://openalex.org/W2130105071","https://openalex.org/W2130945157","https://openalex.org/W2131953240","https://openalex.org/W2133991735","https://openalex.org/W2134532802","https://openalex.org/W2135531683","https://openalex.org/W2137444266","https://openalex.org/W2139667731","https://openalex.org/W2140420135","https://openalex.org/W2143628786","https://openalex.org/W2145172700","https://openalex.org/W2146324651","https://openalex.org/W2148300725","https://openalex.org/W2151293405","https://openalex.org/W2152719134","https://openalex.org/W2152765608","https://openalex.org/W2155819176","https://openalex.org/W2157157003","https://openalex.org/W2157256907","https://openalex.org/W2161331700","https://openalex.org/W2163225965","https://openalex.org/W2166233935","https://openalex.org/W2167006646","https://openalex.org/W2167127477","https://openalex.org/W2167183660","https://openalex.org/W2168231775","https://openalex.org/W2178866977","https://openalex.org/W2197572016","https://openalex.org/W2253802357","https://openalex.org/W2277411172","https://openalex.org/W2298610886","https://openalex.org/W2395325771","https://openalex.org/W2397614738","https://openalex.org/W2407656459","https://openalex.org/W2413160336","https://openalex.org/W2414014505","https://openalex.org/W2469685265","https://openalex.org/W2472063060","https://openalex.org/W2475111634","https://openalex.org/W2479642761","https://openalex.org/W2480915756","https://openalex.org/W2506326107","https://openalex.org/W2508310112","https://openalex.org/W2515274402","https://openalex.org/W2517088688","https://openalex.org/W2518436702","https://openalex.org/W2521383153","https://openalex.org/W2529601819","https://openalex.org/W2531313864","https://openalex.org/W2550802622","https://openalex.org/W2558599134","https://openalex.org/W2560748808","https://openalex.org/W2561580665","https://openalex.org/W2563698238","https://openalex.org/W2568797492","https://openalex.org/W2584976364","https://openalex.org/W2586236260","https://openalex.org/W2588154444","https://openalex.org/W2588487507","https://openalex.org/W2593297177","https://openalex.org/W2598800417","https://openalex.org/W2598936163","https://openalex.org/W2600656194","https://openalex.org/W2600959588","https://openalex.org/W2604134035","https://openalex.org/W2605222169","https://openalex.org/W2610760715","https://openalex.org/W2614586381","https://openalex.org/W2614815016","https://openalex.org/W2616374826","https://openalex.org/W2618235845","https://openalex.org/W2618553145","https://openalex.org/W2622468178","https://openalex.org/W2627036747","https://openalex.org/W2712068521","https://openalex.org/W2729896172","https://openalex.org/W2742497781","https://openalex.org/W2750130602","https://openalex.org/W2751128104","https://openalex.org/W2751474624","https://openalex.org/W2753802402","https://openalex.org/W2755067822","https://openalex.org/W2760285987","https://openalex.org/W2761105681","https://openalex.org/W2761522803","https://openalex.org/W2762968405","https://openalex.org/W2766923756","https://openalex.org/W2767482362","https://openalex.org/W2768025036","https://openalex.org/W2768030986","https://openalex.org/W2773427194","https://openalex.org/W2777416473","https://openalex.org/W2781143971","https://openalex.org/W2783026431","https://openalex.org/W2787171652","https://openalex.org/W2790863554","https://openalex.org/W2791041386","https://openalex.org/W2791408866","https://openalex.org/W2793548666","https://openalex.org/W2794317956","https://openalex.org/W2799293472","https://openalex.org/W2801316281","https://openalex.org/W2802421303","https://openalex.org/W2808890141","https://openalex.org/W2809911284","https://openalex.org/W2810747280","https://openalex.org/W2852090572","https://openalex.org/W2883628966","https://openalex.org/W2885225461","https://openalex.org/W2885436071","https://openalex.org/W2886126921","https://openalex.org/W2887935166","https://openalex.org/W2889977344","https://openalex.org/W2890806217","https://openalex.org/W2890960550","https://openalex.org/W2892135048","https://openalex.org/W2892318814","https://openalex.org/W2892352916","https://openalex.org/W2894357926","https://openalex.org/W2895430781","https://openalex.org/W2895939677","https://openalex.org/W2897551540","https://openalex.org/W2898289136","https://openalex.org/W2900756684","https://openalex.org/W2901804894","https://openalex.org/W2902206211","https://openalex.org/W2902771649","https://openalex.org/W2905168635","https://openalex.org/W2910129845","https://openalex.org/W2910423533","https://openalex.org/W2911360068","https://openalex.org/W2911478235","https://openalex.org/W2912696654","https://openalex.org/W2913414292","https://openalex.org/W2913630382","https://openalex.org/W2914437754","https://openalex.org/W2916037674","https://openalex.org/W2918146112","https://openalex.org/W2919740749","https://openalex.org/W2926994294","https://openalex.org/W2931097084","https://openalex.org/W2934425537","https://openalex.org/W2942037808","https://openalex.org/W2943172756","https://openalex.org/W2943220296","https://openalex.org/W2943747861","https://openalex.org/W2946392820","https://openalex.org/W2947101346","https://openalex.org/W2947959068","https://openalex.org/W2950471695","https://openalex.org/W2951259091","https://openalex.org/W2957458212","https://openalex.org/W2964087368","https://openalex.org/W2965654579","https://openalex.org/W2969261818","https://openalex.org/W2970252989","https://openalex.org/W2970394212","https://openalex.org/W2970686316","https://openalex.org/W2971799438","https://openalex.org/W2972804872","https://openalex.org/W2973319155","https://openalex.org/W2976977668","https://openalex.org/W2978290683","https://openalex.org/W2978939437","https://openalex.org/W2981775974","https://openalex.org/W2982626951","https://openalex.org/W2989859177","https://openalex.org/W2997597898","https://openalex.org/W2997916741","https://openalex.org/W2998620289","https://openalex.org/W2999023297","https://openalex.org/W3000093244","https://openalex.org/W3000185273","https://openalex.org/W3000438116","https://openalex.org/W3000493884","https://openalex.org/W3002987833","https://openalex.org/W3004296379","https://openalex.org/W3007007406","https://openalex.org/W3007965683","https://openalex.org/W3009317513","https://openalex.org/W3010651332","https://openalex.org/W3012866910","https://openalex.org/W3015186969","https://openalex.org/W3016890258","https://openalex.org/W3018373832","https://openalex.org/W3023730834","https://openalex.org/W3025080937","https://openalex.org/W3025374083","https://openalex.org/W3026018883","https://openalex.org/W3026769950","https://openalex.org/W3035934119","https://openalex.org/W3036078269","https://openalex.org/W3036895273","https://openalex.org/W3037913636","https://openalex.org/W3044089250","https://openalex.org/W3059233071","https://openalex.org/W3082563867","https://openalex.org/W3087328080","https://openalex.org/W3089198868","https://openalex.org/W3089476715","https://openalex.org/W3090879627","https://openalex.org/W3091564973","https://openalex.org/W3092468042","https://openalex.org/W3093405588","https://openalex.org/W3094334480","https://openalex.org/W3102483432","https://openalex.org/W3105597744","https://openalex.org/W3111807297","https://openalex.org/W3113160419","https://openalex.org/W3115642537","https://openalex.org/W3119223726","https://openalex.org/W3123476146","https://openalex.org/W3125030132","https://openalex.org/W3125753820","https://openalex.org/W3126358966","https://openalex.org/W3129943594","https://openalex.org/W3130159727","https://openalex.org/W3131300600","https://openalex.org/W3133782054","https://openalex.org/W3134414547","https://openalex.org/W3136392752","https://openalex.org/W3137286939","https://openalex.org/W3139085801","https://openalex.org/W3141671875","https://openalex.org/W3144346450","https://openalex.org/W3145659627","https://openalex.org/W3145948343","https://openalex.org/W3146209640","https://openalex.org/W3154493485","https://openalex.org/W3155198065","https://openalex.org/W3157296292","https://openalex.org/W3157339569","https://openalex.org/W3159077390","https://openalex.org/W3159116119","https://openalex.org/W3164896384","https://openalex.org/W3165274349","https://openalex.org/W3165520347","https://openalex.org/W3167756515","https://openalex.org/W3174235260","https://openalex.org/W3194258763","https://openalex.org/W3196160028","https://openalex.org/W3205122562","https://openalex.org/W3209927131","https://openalex.org/W3210249191","https://openalex.org/W3211199092","https://openalex.org/W3211854075","https://openalex.org/W3214860672","https://openalex.org/W3216938867","https://openalex.org/W3217643372","https://openalex.org/W4200036419","https://openalex.org/W4205910945","https://openalex.org/W4206066092","https://openalex.org/W4206964640","https://openalex.org/W4210623697","https://openalex.org/W4210915913","https://openalex.org/W4211073154","https://openalex.org/W4212844715","https://openalex.org/W4214574386","https://openalex.org/W4220961380","https://openalex.org/W4224757236","https://openalex.org/W4224983143","https://openalex.org/W4226323879","https://openalex.org/W4229041475","https://openalex.org/W4229077904","https://openalex.org/W4247878364","https://openalex.org/W4250057060","https://openalex.org/W4280653281","https://openalex.org/W4283033049","https://openalex.org/W4283066304","https://openalex.org/W4284879752","https://openalex.org/W4290613458","https://openalex.org/W4294573005","https://openalex.org/W4296551890","https://openalex.org/W4297963012","https://openalex.org/W4297988534","https://openalex.org/W4301372077","https://openalex.org/W4306393265","https://openalex.org/W4307231822","https://openalex.org/W4308150318","https://openalex.org/W4308916361","https://openalex.org/W4311807790","https://openalex.org/W4313530446","https://openalex.org/W4313555692","https://openalex.org/W4322604190","https://openalex.org/W4327677959"],"related_works":["https://openalex.org/W6966417518","https://openalex.org/W7130840701","https://openalex.org/W4377835001","https://openalex.org/W3090563031","https://openalex.org/W3040369872","https://openalex.org/W1842692605","https://openalex.org/W2911478235","https://openalex.org/W2773427194","https://openalex.org/W4402320115","https://openalex.org/W4372201270"],"abstract_inverted_index":{"As":[0],"a":[1,104,120],"recently":[2],"discovered":[3],"waste":[4],"removal":[5],"system":[6,12,53,91,130],"in":[7,20,93,106],"the":[8,22,25,38,45,59,73,94,107,110,124,127,132],"brain,":[9],"cerebral":[10,39,51,80,111],"lymphatic":[11,40,52,81,112],"is":[13,34,54,86,102,119],"thought":[14],"to":[15,56,64],"play":[16],"an":[17],"important":[18],"role":[19],"regulating":[21],"homeostasis":[23],"of":[24,44,50,61,79,109,123],"central":[26,128],"nervous":[27,129],"system.":[28,41,82,113,134],"Currently,":[29],"more":[30,32],"and":[31,47,63,76,98,131],"attention":[33],"being":[35],"focused":[36],"on":[37],"Further":[42],"understanding":[43],"structural":[46,74],"functional":[48,77],"characteristics":[49,78],"essential":[55],"better":[57],"understand":[58],"pathogenesis":[60],"diseases":[62,92],"explore":[65],"therapeutic":[66],"approaches.":[67],"In":[68],"this":[69],"review,":[70],"we":[71,115],"summarize":[72],"components":[75],"More":[83],"importantly,":[84],"it":[85,118],"closely":[87],"associated":[88],"with":[89],"peripheral":[90,133],"gastrointestinal":[95],"tract,":[96],"liver,":[97],"kidney.":[99],"However,":[100,114],"there":[101],"still":[103],"gap":[105],"study":[108],"believe":[116],"that":[117],"critical":[121],"mediator":[122],"interactions":[125],"between":[126]},"counts_by_year":[{"year":2026,"cited_by_count":7},{"year":2025,"cited_by_count":9},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":1}],"updated_date":"2026-11-13T13:42:25.865203","created_date":"2023-05-25T00:00:00"}
