{"id":"https://openalex.org/W4377047205","doi":"https://doi.org/10.1097/01.gox.0000938380.41422.05","title":"SP09. Allogeneic Adipose Tissue-derived Matrix Mitigate Radiation-induced Fibrosis","display_name":"SP09. Allogeneic Adipose Tissue-derived Matrix Mitigate Radiation-induced Fibrosis","publication_year":2023,"publication_date":"2023-05-01","ids":{"openalex":"https://openalex.org/W4377047205","doi":"https://doi.org/10.1097/01.gox.0000938380.41422.05"},"language":"en","primary_location":{"id":"doi:10.1097/01.gox.0000938380.41422.05","doi":"https://doi.org/10.1097/01.gox.0000938380.41422.05","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1097/01.gox.0000938380.41422.05","pdf_url":null,"source":{"id":"https://openalex.org/S2754281505","display_name":"Plastic & Reconstructive Surgery Global Open","issn_l":"2169-7574","issn":["2169-7574"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","jufo-1","ki-jl-1","norway-1","oarl","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310318547","host_organization_name":"Wolters Kluwer","host_organization_lineage":["https://openalex.org/P4310318547"],"host_organization_lineage_names":["Wolters Kluwer"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Plastic and Reconstructive Surgery - Global Open","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"http://dx.doi.org/10.1097/01.gox.0000938380.41422.05","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5033812116","display_name":"Yusuf Surucu","orcid":"https://orcid.org/0000-0003-3393-0434","observed_orcids":["https://orcid.org/0000-0003-3393-0434"]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yusuf Surucu","raw_affiliation_strings":["University of Pittsburgh, Pittsburgh, PA, USA","This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Pittsburgh, Pittsburgh, PA, USA","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024472877","display_name":"Somaiah Chinnapaka","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Somaiah Chinnapaka","raw_affiliation_strings":["University of Pittsburgh, Pittsburgh, PA, USA","This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Pittsburgh, Pittsburgh, PA, USA","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081117793","display_name":"Katherine S. Yang","orcid":"https://orcid.org/0000-0003-0182-950X","observed_orcids":["https://orcid.org/0000-0003-0182-950X"]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Katherine S. Yang","raw_affiliation_strings":["University of Pittsburgh, Pittsburgh, PA, USA","This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Pittsburgh, Pittsburgh, PA, USA","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078588576","display_name":"Michael W. Epperly","orcid":"https://orcid.org/0000-0002-6214-6887","observed_orcids":["https://orcid.org/0000-0002-6214-6887"]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael W. Epperly","raw_affiliation_strings":["University of Pittsburgh, Pittsburgh, PA, USA","This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Pittsburgh, Pittsburgh, PA, USA","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063266916","display_name":"Joel S. Greenberger","orcid":"https://orcid.org/0000-0003-2271-7566","observed_orcids":["https://orcid.org/0000-0003-2271-7566"]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Joel S. Greenberger","raw_affiliation_strings":["University of Pittsburgh, Pittsburgh, PA, USA","This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Pittsburgh, Pittsburgh, PA, USA","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022646898","display_name":"Peter J. Rubin","orcid":"https://orcid.org/0000-0003-1148-6205","observed_orcids":["https://orcid.org/0000-0003-1148-6205"]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Peter Rubin","raw_affiliation_strings":["University of Pittsburgh, Pittsburgh, PA, USA","This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Pittsburgh, Pittsburgh, PA, USA","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5040532140","display_name":"Asim Ejaz","orcid":"https://orcid.org/0000-0002-5605-0010","observed_orcids":["https://orcid.org/0000-0002-5605-0010"]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Asim Ejaz","raw_affiliation_strings":["University of Pittsburgh, Pittsburgh, PA, USA","This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Pittsburgh, Pittsburgh, PA, USA","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I170201317"],"apc_list":{"value":2195,"currency":"USD","value_usd":2195},"apc_paid":{"value":2195,"currency":"USD","value_usd":2195},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.07865974,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"11","issue":"5S","first_page":"125","last_page":"125"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11359","display_name":"Effects of Radiation Exposure","score":0.9253000020980835,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11359","display_name":"Effects of Radiation Exposure","score":0.9253000020980835,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12264","display_name":"Tissue Engineering and Regenerative Medicine","score":0.034299999475479126,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10771","display_name":"Wound Healing and Treatments","score":0.008899999782443047,"subfield":{"id":"https://openalex.org/subfields/2742","display_name":"Rehabilitation"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/radiation-induced-fibrosis","display_name":"radiation-induced fibrosis","score":0.9940000176429749},{"id":"https://openalex.org/keywords/allogeneic-cell-therapy","display_name":"allogeneic cell therapy","score":0.7300000190734863},{"id":"https://openalex.org/keywords/skin-fibrosis","display_name":"skin fibrosis","score":0.8500000238418579},{"id":"https://openalex.org/keywords/collagen-deposition","display_name":"collagen deposition","score":0.8349999785423279},{"id":"https://openalex.org/keywords/transforming-growth-factor-beta","display_name":"TGF-beta","score":0.7480000257492065},{"id":"https://openalex.org/keywords/connective-tissue-growth-factor","display_name":"connective tissue growth factor","score":0.9779999852180481},{"id":"https://openalex.org/keywords/tnf-alpha","display_name":"TNF-\u03b1","score":0.8980000019073486},{"id":"https://openalex.org/keywords/fibroblast-proliferation","display_name":"fibroblast proliferation","score":0.7789999842643738},{"id":"https://openalex.org/keywords/adipose-derived-stem-cells","display_name":"adipose-derived stem cells","score":0.8360000252723694},{"id":"https://openalex.org/keywords/profibrotic-gene-expression","display_name":"profibrotic gene expression","score":0.7770000100135803}],"concepts":[{"id":"https://openalex.org/C2780559512","wikidata":"https://www.wikidata.org/wiki/Q605709","display_name":"Fibrosis","level":2,"score":0.8581417798995972},{"id":"https://openalex.org/C171089720","wikidata":"https://www.wikidata.org/wiki/Q193583","display_name":"Adipose tissue","level":2,"score":0.7928422689437866},{"id":"https://openalex.org/C189165786","wikidata":"https://www.wikidata.org/wiki/Q193825","display_name":"Extracellular matrix","level":2,"score":0.7725955247879028},{"id":"https://openalex.org/C2780631158","wikidata":"https://www.wikidata.org/wiki/Q14907752","display_name":"CTGF","level":4,"score":0.5982583165168762},{"id":"https://openalex.org/C2780381497","wikidata":"https://www.wikidata.org/wiki/Q463418","display_name":"Fibroblast","level":3,"score":0.5254934430122375},{"id":"https://openalex.org/C171056886","wikidata":"https://www.wikidata.org/wiki/Q193119","display_name":"Regeneration (biology)","level":2,"score":0.4615490734577179},{"id":"https://openalex.org/C518705261","wikidata":"https://www.wikidata.org/wiki/Q25615","display_name":"Connective tissue","level":2,"score":0.4588523507118225},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.38224661350250244},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3783770203590393},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3571542501449585},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.2693430781364441},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.26733940839767456},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2626609802246094},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.24184048175811768},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.21489796042442322},{"id":"https://openalex.org/C2775960820","wikidata":"https://www.wikidata.org/wiki/Q408378","display_name":"Growth factor","level":3,"score":0.20859426259994507},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.06662079691886902},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1097/01.gox.0000938380.41422.05","doi":"https://doi.org/10.1097/01.gox.0000938380.41422.05","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1097/01.gox.0000938380.41422.05","pdf_url":null,"source":{"id":"https://openalex.org/S2754281505","display_name":"Plastic & Reconstructive Surgery Global Open","issn_l":"2169-7574","issn":["2169-7574"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","jufo-1","ki-jl-1","norway-1","oarl","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310318547","host_organization_name":"Wolters Kluwer","host_organization_lineage":["https://openalex.org/P4310318547"],"host_organization_lineage_names":["Wolters Kluwer"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Plastic and Reconstructive Surgery - Global Open","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:10194509","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10194509","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10194509/pdf/gox-11-125b.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Plast Reconstr Surg Glob Open","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:bcfae6c4e5a34a798d61f30a9624fac4","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/bcfae6c4e5a34a798d61f30a9624fac4","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Plastic and Reconstructive Surgery, Global Open, Vol 11, Iss 5S, Pp 125-125 (2023)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1097/01.gox.0000938380.41422.05","doi":"https://doi.org/10.1097/01.gox.0000938380.41422.05","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1097/01.gox.0000938380.41422.05","pdf_url":null,"source":{"id":"https://openalex.org/S2754281505","display_name":"Plastic & Reconstructive Surgery Global Open","issn_l":"2169-7574","issn":["2169-7574"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","jufo-1","ki-jl-1","norway-1","oarl","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310318547","host_organization_name":"Wolters Kluwer","host_organization_lineage":["https://openalex.org/P4310318547"],"host_organization_lineage_names":["Wolters Kluwer"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Plastic and Reconstructive Surgery - Global Open","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4385327024","https://openalex.org/W2885525297","https://openalex.org/W4385912863","https://openalex.org/W4392907606","https://openalex.org/W4402004301","https://openalex.org/W4402372495","https://openalex.org/W2936286804","https://openalex.org/W4312789045","https://openalex.org/W4385194461","https://openalex.org/W4377047621"],"abstract_inverted_index":{"PURPOSE:":[0],"Radiation-induced":[1],"fibrosis":[2,59,76],"(RIF)":[3],"is":[4],"a":[5,57,107,238,245],"complex":[6],"tissue":[7,25],"response":[8],"characterized":[9],"by":[10],"massive":[11],"deposition":[12,103],"of":[13,24,29,36,75,95,109,136,139,184,186,233],"extracellular":[14],"matrix":[15,41,214],"(ECM)":[16],"and":[17,27,61,81,89,101,115,123,164,193,231],"excessive":[18],"fibroblast":[19],"proliferation":[20],"resulting":[21],"in":[22,113,156,199,203],"loss":[23],"function":[26],"quality":[28],"life.":[30],"This":[31],"study":[32],"tested":[33],"the":[34,67,73,134,172,182,229,234],"efficacy":[35],"an":[37,218],"allograft":[38],"adipose":[39,82,212],"tissue-derived":[40,213],"(AATM)":[42,215],"to":[43,71,132,171,222,227],"mitigate":[44,223],"RIF.":[45],"METHODS:":[46],"We":[47],"used":[48],"40":[49],"Gy":[50],"hind":[51],"limb":[52,96,167],"irradiated":[53,140,204],"C57BL/6":[54],"mice":[55],"as":[56,106,152,154,244],"skin":[58,98,117],"model":[60],"injected":[62],"200":[63],"\u03bcl":[64],"AATM":[65,143,149],"on":[66,77,144],"14th":[68],"post-irradiation":[69],"day":[70,78],"investigate":[72],"inhibition":[74],"40.":[79],"PBS":[80],"stem":[83],"cell":[84],"(ASC)":[85],"injections":[86],"were":[87,118,130],"negative":[88,173],"positive":[90],"controls,":[91],"respectively.":[92],"The":[93],"degree":[94],"excursion,":[97],"epithelium":[99],"thickness,":[100,161],"collagen":[102,162],"was":[104,151,197],"measured":[105,119],"marker":[108],"fibrosis.":[110,224],"Molecular":[111],"changes":[112],"treated":[114],"control":[116],"using":[120],"real-time":[121,178],"PCR":[122,179],"Luminex":[124],"assay.":[125],"In":[126,175],"vitro,":[127],"trans-well":[128],"studies":[129,202,226],"performed":[131],"analyze":[133],"effect":[135],"direct":[137,200],"coculture":[138,201],"cells":[141],"with":[142],"pro-fibrotic":[145,187],"gene":[146],"expressions.":[147],"RESULTS:":[148],"treatment":[150],"successful":[153],"ASC":[155],"diminishing":[157],"fibrosis;":[158],"decreased":[159],"epithelial":[160],"deposition,":[163],"significantly":[165],"improved":[166],"excursion":[168],"achieved":[169],"compared":[170],"control.":[174],"AATM-treated":[176],"mice,":[177],"analysis":[180],"revealed":[181],"down-regulation":[183,196],"expression":[185],"genes":[188],"TGF-\u03b2,":[189],"CTGF,":[190],"Col1,":[191],"Col2,":[192],"TNF-alpha;":[194],"similar":[195],"observed":[198],"fibroblasts.":[205],"CONCLUSION:":[206],"Our":[207],"findings":[208],"suggest":[209],"that":[210],"allogeneic":[211],"can":[216],"be":[217,237],"effective":[219],"therapeutic":[220],"option":[221],"Further":[225],"optimize":[228],"time":[230],"dose":[232],"therapy":[235],"will":[236],"significant":[239],"step":[240],"toward":[241],"clinical":[242],"adaptation":[243],"RIF":[246],"treatment.":[247]},"counts_by_year":[],"updated_date":"2026-10-29T09:56:32.521200","created_date":"2023-05-19T00:00:00"}