{"id":"https://openalex.org/W4376279727","doi":"https://doi.org/10.3389/fpubh.2023.1160841","title":"Retrospective analysis on distribution and antifungal susceptibility profile of Candida in clinical samples: a study from Southern India","display_name":"Retrospective analysis on distribution and antifungal susceptibility profile of Candida in clinical samples: a study from Southern India","publication_year":2023,"publication_date":"2023-05-12","ids":{"openalex":"https://openalex.org/W4376279727","doi":"https://doi.org/10.3389/fpubh.2023.1160841","pmid":"https://pubmed.ncbi.nlm.nih.gov/37261242","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/10228385"},"language":"en","primary_location":{"id":"doi:10.3389/fpubh.2023.1160841","doi":"https://doi.org/10.3389/fpubh.2023.1160841","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fpubh.2023.1160841","pdf_url":"https://www.frontiersin.org/articles/10.3389/fpubh.2023.1160841/pdf","source":{"id":"https://openalex.org/S2595931848","display_name":"Frontiers in Public Health","issn_l":"2296-2565","issn":["2296-2565"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Public Health","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.frontiersin.org/articles/10.3389/fpubh.2023.1160841/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5032149297","display_name":"S. Umamaheshwari","orcid":"https://orcid.org/0000-0003-0365-5080","observed_orcids":["https://orcid.org/0000-0003-0365-5080"]},"institutions":[{"id":"https://openalex.org/I126824641","display_name":"JSS Academy of Higher Education and Research","ror":"https://ror.org/013x70191","country_code":"IN","type":"education","lineage":["https://openalex.org/I126824641"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Umamaheshwari S.","raw_affiliation_strings":["Department of Microbiology, School of Life Sciences, JSS Academy of Higher Education and Research, Mysuru, Karnataka, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, School of Life Sciences, JSS Academy of Higher Education and Research, Mysuru, Karnataka, India","institution_ids":["https://openalex.org/I126824641"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110486193","display_name":"Mahadevaiah Neelambike Sumana","orcid":"https://orcid.org/0000-0002-8877-0602","observed_orcids":["https://orcid.org/0000-0002-8877-0602"]},"institutions":[{"id":"https://openalex.org/I126824641","display_name":"JSS Academy of Higher Education and Research","ror":"https://ror.org/013x70191","country_code":"IN","type":"education","lineage":["https://openalex.org/I126824641"]},{"id":"https://openalex.org/I86826812","display_name":"JSS Medical College and Hospital","ror":"https://ror.org/02xf0fd83","country_code":"IN","type":"education","lineage":["https://openalex.org/I86826812"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"M. N. Sumana","raw_affiliation_strings":["Department of Microbiology, JSS Medical College and Hospital, JSS Academy of Higher Education and Research, Mysuru, Karnataka, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, JSS Medical College and Hospital, JSS Academy of Higher Education and Research, Mysuru, Karnataka, India","institution_ids":["https://openalex.org/I126824641","https://openalex.org/I86826812"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5110486193"],"corresponding_institution_ids":["https://openalex.org/I126824641","https://openalex.org/I86826812"],"apc_list":{"value":3295,"currency":"USD","value_usd":3295},"apc_paid":{"value":3295,"currency":"USD","value_usd":3295},"fwci":3.4983,"has_fulltext":true,"cited_by_count":17,"citation_normalized_percentile":{"value":0.93170941,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"11","issue":null,"first_page":"1160841","last_page":"1160841"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10150","display_name":"Antifungal resistance and susceptibility","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10150","display_name":"Antifungal resistance and susceptibility","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12668","display_name":"Yeasts and Rust Fungi Studies","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11037","display_name":"Fungal Infections and Studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/candida","display_name":"Candida","score":0.8799999952316284},{"id":"https://openalex.org/keywords/candidiasis","display_name":"candidiasis","score":0.7519999742507935},{"id":"https://openalex.org/keywords/antifungal-susceptibility","display_name":"antifungal susceptibility","score":0.9210000038146973},{"id":"https://openalex.org/keywords/antifungal-resistance","display_name":"antifungal resistance","score":0.7910000085830688},{"id":"https://openalex.org/keywords/candida-tropicalis","display_name":"Candida tropicalis","score":0.7630000114440918},{"id":"https://openalex.org/keywords/candida-albicans","display_name":"Candida albicans","score":0.9829999804496765},{"id":"https://openalex.org/keywords/non-albicans-candida","display_name":"non-albicans Candida","score":0.9890000224113464},{"id":"https://openalex.org/keywords/candida-glabrata","display_name":"Candida glabrata","score":0.8970000147819519},{"id":"https://openalex.org/keywords/candida-parapsilosis","display_name":"Candida parapsilosis","score":0.9800000190734863},{"id":"https://openalex.org/keywords/candida-krusei","display_name":"Candida krusei","score":0.9190000295639038},{"id":"https://openalex.org/keywords/candida-haemulonii","display_name":"Candida haemulonii","score":0.984000027179718},{"id":"https://openalex.org/keywords/candida-pelliculosa","display_name":"Candida pelliculosa","score":0.8600000143051147},{"id":"https://openalex.org/keywords/yarrowia-lipolytica","display_name":"Yarrowia lipolytica","score":0.9940000176429749}],"concepts":[{"id":"https://openalex.org/C2775835631","wikidata":"https://www.wikidata.org/wiki/Q143138","display_name":"Candida tropicalis","level":3,"score":0.8814823627471924},{"id":"https://openalex.org/C2780670043","wikidata":"https://www.wikidata.org/wiki/Q139137","display_name":"Candida glabrata","level":3,"score":0.8242486119270325},{"id":"https://openalex.org/C2779443200","wikidata":"https://www.wikidata.org/wiki/Q144068","display_name":"Candida parapsilosis","level":3,"score":0.7574844360351562},{"id":"https://openalex.org/C2780917455","wikidata":"https://www.wikidata.org/wiki/Q310443","display_name":"Candida albicans","level":2,"score":0.742848813533783},{"id":"https://openalex.org/C2781425774","wikidata":"https://www.wikidata.org/wiki/Q289229","display_name":"Candida krusei","level":4,"score":0.667296290397644},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.6300911903381348},{"id":"https://openalex.org/C2779629538","wikidata":"https://www.wikidata.org/wiki/Q412223","display_name":"Amphotericin B","level":3,"score":0.5685966610908508},{"id":"https://openalex.org/C145081991","wikidata":"https://www.wikidata.org/wiki/Q2576388","display_name":"Corpus albicans","level":3,"score":0.5645931959152222},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5020914077758789},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.34004440903663635},{"id":"https://openalex.org/C2779548794","wikidata":"https://www.wikidata.org/wiki/Q578726","display_name":"Antifungal","level":2,"score":0.2959892749786377}],"mesh":[{"descriptor_ui":"D000935","descriptor_name":"Antifungal Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000935","descriptor_name":"Antifungal Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D002175","descriptor_name":"Candida","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008826","descriptor_name":"Microbial Sensitivity Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D025141","descriptor_name":"Drug Resistance, Fungal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.3389/fpubh.2023.1160841","doi":"https://doi.org/10.3389/fpubh.2023.1160841","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fpubh.2023.1160841","pdf_url":"https://www.frontiersin.org/articles/10.3389/fpubh.2023.1160841/pdf","source":{"id":"https://openalex.org/S2595931848","display_name":"Frontiers in Public Health","issn_l":"2296-2565","issn":["2296-2565"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Public Health","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:10228385","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10228385","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10228385/pdf/fpubh-11-1160841.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Front Public Health","raw_type":"Text"},{"id":"pmid:37261242","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37261242","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in public health","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:9054d148cba6488d93bdda087f34b43f","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/9054d148cba6488d93bdda087f34b43f","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Public Health, Vol 11 (2023)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3389/fpubh.2023.1160841","doi":"https://doi.org/10.3389/fpubh.2023.1160841","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fpubh.2023.1160841","pdf_url":"https://www.frontiersin.org/articles/10.3389/fpubh.2023.1160841/pdf","source":{"id":"https://openalex.org/S2595931848","display_name":"Frontiers in Public Health","issn_l":"2296-2565","issn":["2296-2565"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Public Health","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.979200005531311}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320319237","display_name":"JSS Academy of Higher Education and Research","ror":"https://ror.org/013x70191"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4376279727.pdf","grobid_xml":"https://content.openalex.org/works/W4376279727.grobid-xml"},"referenced_works_count":29,"referenced_works":["https://openalex.org/W184976125","https://openalex.org/W1784319065","https://openalex.org/W2018414863","https://openalex.org/W2031681479","https://openalex.org/W2031897355","https://openalex.org/W2042566612","https://openalex.org/W2054164850","https://openalex.org/W2059425495","https://openalex.org/W2064202855","https://openalex.org/W2065961802","https://openalex.org/W2095696028","https://openalex.org/W2098169836","https://openalex.org/W2110892287","https://openalex.org/W2135840745","https://openalex.org/W2141563676","https://openalex.org/W2161710216","https://openalex.org/W2171501062","https://openalex.org/W2511497456","https://openalex.org/W2766095378","https://openalex.org/W2895934041","https://openalex.org/W2899489704","https://openalex.org/W2901050404","https://openalex.org/W2908213577","https://openalex.org/W2933108853","https://openalex.org/W3042483822","https://openalex.org/W3121726782","https://openalex.org/W4205649825","https://openalex.org/W4211178015","https://openalex.org/W4404016454"],"related_works":["https://openalex.org/W4413417889","https://openalex.org/W4407304906","https://openalex.org/W7160858541","https://openalex.org/W7220372557","https://openalex.org/W4296478652","https://openalex.org/W7216126701","https://openalex.org/W2619730505","https://openalex.org/W4386191160","https://openalex.org/W4392754507","https://openalex.org/W3016530259"],"abstract_inverted_index":{"Introduction":[0],"Candida":[1,38,63,92,97,104,110,125,128,130,141,149,234,241,275],"is":[2],"one":[3,199],"of":[4,9,37,75,89,248,254],"the":[5,35,59,72,133,249],"rising":[6],"primary":[7],"causes":[8],"infections":[10],"connected":[11],"with":[12],"health":[13],"care.":[14],"However,":[15],"their":[16,43],"distribution":[17,36],"and":[18,46,71,127,148,153,155,191,233,240,252,266,273],"susceptibility":[19,180],"patterns":[20],"vary":[21],"widely":[22],"amongst":[23],"different":[24,91,255],"regions.":[25],"Method":[26],"The":[27,179,246],"study":[28],"was":[29,65,77,112,132,143,206],"carried":[30],"out":[31],"to":[32,79,114,173,198,208,218,238,243,260,270],"retrospectively":[33],"analyze":[34],"in":[39,48,53,67,157],"various":[40],"clinical":[41,69],"samples,":[42,70],"species":[44,93,135,256],"types":[45],"susceptibility,":[47],"a":[49,118],"tertiary":[50],"care":[51],"hospital,":[52],"India":[54],"for":[55,84,167],"4":[56],"years":[57],"using":[58],"Vitek-2":[60],"database.":[61],"Results":[62],"infection":[64,76],"identified":[66,116],"751":[68],"major":[73],"source":[74],"found":[78,113],"be":[80,115],"urine":[81,152],"samples":[82],"accounting":[83],"about":[85],"58.32%.":[86],"A":[87],"total":[88],"18":[90],"were":[94,137,189,196],"recorded.":[95],"Non-albicans":[96],"(NAC)":[98],"73.64%":[99],"(n":[100,107,169,176,185,193,214,222],"=":[101,108,170,177,186,194,215,223],"553)":[102],"predominated":[103],"albicans":[105,165,220],"26.36%":[106],"198).":[109],"tropicalis":[111,131,212],"at":[117],"higher":[119],"frequency":[120],"followed":[121],"by":[122,210],"C.":[123,164,211,219,227,231],"albicans,":[124,228],"glabrata":[126,232],"parapsilosis.":[129],"only":[134],"which":[136],"recovered":[138],"from":[139,146,151,226],"bile;":[140],"pelliculosa":[142],"recorded":[144],"merely":[145],"blood":[147,154],"lipolytica":[150],"not":[156],"any":[158],"other":[159],"samples.":[160],"In":[161],"vaginal":[162],"swabs,":[163],"accounted":[166],"63.64%":[168],"14)":[171],"compared":[172,217],"NAC":[174],"36.36%":[175],"8).":[178,224],"test":[181],"revealed":[182],"that":[183],"75.44%":[184],"559)":[187],"isolates":[188],"susceptible":[190],"24.56%":[192],"182)":[195],"resistant":[197],"or":[200],"more":[201],"drugs":[202],"tested.":[203],"Major":[204],"resistance":[205,237,251],"exhibited":[207],"flucytosine":[209],"77.46%":[213],"55)":[216],"11.27%":[221],"Apart":[225],"NAC-C.":[229],"tropicalis,":[230],"krusei":[235],"showed":[236],"echinocandins,":[239],"haemulonii":[242],"amphotericin-B.":[244],"Conclusion":[245],"knowledge":[247],"incidence,":[250],"emergence":[253],"might":[257],"guide":[258],"clinicians":[259],"select":[261],"an":[262],"appropriate":[263],"antifungal":[264],"therapy":[265],"plan":[267],"effective":[268],"strategies":[269],"control":[271],"invasive":[272],"systemic":[274],"infections.":[276]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":8},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2023-05-13T00:00:00"}