{"id":"https://openalex.org/W4375950333","doi":"https://doi.org/10.1080/14786419.2023.2210738","title":"Phytochemical constituents from the rhizomes of Kaempferia parviflora Wall. ex Baker and their acetylcholinesterase inhibitory activity","display_name":"Phytochemical constituents from the rhizomes of Kaempferia parviflora Wall. ex Baker and their acetylcholinesterase inhibitory activity","publication_year":2023,"publication_date":"2023-05-08","ids":{"openalex":"https://openalex.org/W4375950333","doi":"https://doi.org/10.1080/14786419.2023.2210738","pmid":"https://pubmed.ncbi.nlm.nih.gov/37157866"},"language":"en","primary_location":{"id":"doi:10.1080/14786419.2023.2210738","doi":"https://doi.org/10.1080/14786419.2023.2210738","is_oa":false,"landing_page_url":"https://doi.org/10.1080/14786419.2023.2210738","pdf_url":null,"source":{"id":"https://openalex.org/S205999849","display_name":"Natural Product Research","issn_l":"1478-6419","issn":["1478-6419","1478-6427"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Natural Product Research","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113139645","display_name":"Tr\u1ea7n Th\u1ecb Thu H\u00e0","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210126287","display_name":"Thai Nguyen University of Agriculture and Forestry","ror":"https://ror.org/028zxrr95","country_code":"VN","type":"education","lineage":["https://openalex.org/I4210126287"]}],"countries":["VN"],"is_corresponding":true,"raw_author_name":"Tran Thi Thu Ha","raw_affiliation_strings":["Forestry Faculty, Thai Nguyen University of Agriculture and Forestry, Thai Nguyen City, Vietnam","Institute of Forestry and Sustainable Development, Thai Nguyen University of Agriculture and Forestry, Thai Nguyen City, Vietnam"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Forestry Faculty, Thai Nguyen University of Agriculture and Forestry, Thai Nguyen City, Vietnam","institution_ids":["https://openalex.org/I4210126287"]},{"raw_affiliation_string":"Institute of Forestry and Sustainable Development, Thai Nguyen University of Agriculture and Forestry, Thai Nguyen City, Vietnam","institution_ids":["https://openalex.org/I4210126287"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102778857","display_name":"Nguy\u1ec5n Ti\u1ebfn D\u0169ng","orcid":"https://orcid.org/0000-0002-6511-1698","observed_orcids":["https://orcid.org/0000-0002-6511-1698"]},"institutions":[{"id":"https://openalex.org/I4210126287","display_name":"Thai Nguyen University of Agriculture and Forestry","ror":"https://ror.org/028zxrr95","country_code":"VN","type":"education","lineage":["https://openalex.org/I4210126287"]}],"countries":["VN"],"is_corresponding":false,"raw_author_name":"Nguyen Tien Dung","raw_affiliation_strings":["Forestry Faculty, Thai Nguyen University of Agriculture and Forestry, Thai Nguyen City, Vietnam"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Forestry Faculty, Thai Nguyen University of Agriculture and Forestry, Thai Nguyen City, Vietnam","institution_ids":["https://openalex.org/I4210126287"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035305741","display_name":"Khu\u1ea5t H\u1eefu Trung","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210155593","display_name":"Agricultural Genetics Institute","ror":"https://ror.org/05sswkg52","country_code":"VN","type":"facility","lineage":["https://openalex.org/I4210155593"]}],"countries":["VN"],"is_corresponding":false,"raw_author_name":"Khuat Huu Trung","raw_affiliation_strings":["Deparment of Plant Physiology and Biochemistry, Agricultural Gennetics Institute, Hanoi, Vietnam"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Deparment of Plant Physiology and Biochemistry, Agricultural Gennetics Institute, Hanoi, Vietnam","institution_ids":["https://openalex.org/I4210155593"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016357695","display_name":"B\u00f9i H\u1eefu T\u00e0i","orcid":"https://orcid.org/0000-0002-2034-3786","observed_orcids":["https://orcid.org/0000-0002-2034-3786"]},"institutions":[{"id":"https://openalex.org/I4405269321","display_name":"Graduate University of Science and Technology","ror":"https://ror.org/03t0zs859","country_code":"VN","type":"education","lineage":["https://openalex.org/I4405269321"]},{"id":"https://openalex.org/I70349855","display_name":"Vietnam Academy of Science and Technology","ror":"https://ror.org/02wsd5p50","country_code":"VN","type":"government","lineage":["https://openalex.org/I70349855"]}],"countries":["VN"],"is_corresponding":false,"raw_author_name":"Bui Huu Tai","raw_affiliation_strings":["Department of Structural Research, Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), Hanoi, Vietnam","Faculty of Chemistry, Graduate University of Science and Technology, VAST, Hanoi, Vietnam"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Structural Research, Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), Hanoi, Vietnam","institution_ids":["https://openalex.org/I70349855"]},{"raw_affiliation_string":"Faculty of Chemistry, Graduate University of Science and Technology, VAST, Hanoi, Vietnam","institution_ids":["https://openalex.org/I4405269321","https://openalex.org/I70349855"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5014245013","display_name":"Phan V\u0103n Ki\u1ec7m","orcid":"https://orcid.org/0000-0003-0756-6990","observed_orcids":["https://orcid.org/0000-0003-0756-6990"]},"institutions":[{"id":"https://openalex.org/I4405269321","display_name":"Graduate University of Science and Technology","ror":"https://ror.org/03t0zs859","country_code":"VN","type":"education","lineage":["https://openalex.org/I4405269321"]},{"id":"https://openalex.org/I70349855","display_name":"Vietnam Academy of Science and Technology","ror":"https://ror.org/02wsd5p50","country_code":"VN","type":"government","lineage":["https://openalex.org/I70349855"]}],"countries":["VN"],"is_corresponding":true,"raw_author_name":"Phan Van Kiem","raw_affiliation_strings":["Department of Structural Research, Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), Hanoi, Vietnam","Faculty of Chemistry, Graduate University of Science and Technology, VAST, Hanoi, Vietnam"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Structural Research, Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), Hanoi, Vietnam","institution_ids":["https://openalex.org/I70349855"]},{"raw_affiliation_string":"Faculty of Chemistry, Graduate University of Science and Technology, VAST, Hanoi, Vietnam","institution_ids":["https://openalex.org/I4405269321","https://openalex.org/I70349855"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5014245013","https://openalex.org/A5113139645"],"corresponding_institution_ids":["https://openalex.org/I4210126287","https://openalex.org/I4405269321","https://openalex.org/I70349855"],"apc_list":null,"apc_paid":null,"fwci":1.6791,"has_fulltext":false,"cited_by_count":11,"citation_normalized_percentile":{"value":0.803386,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":97},"biblio":{"volume":"38","issue":"6","first_page":"994","last_page":"1001"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12347","display_name":"Ginger and Zingiberaceae research","score":0.8920999765396118,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12347","display_name":"Ginger and Zingiberaceae research","score":0.8920999765396118,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11613","display_name":"Phytochemistry and Biological Activities","score":0.040300000458955765,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12257","display_name":"Bioactive natural compounds","score":0.03999999910593033,"subfield":{"id":"https://openalex.org/subfields/3002","display_name":"Drug Discovery"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/kaempferia-parviflora","display_name":"Kaempferia parviflora","score":1.0},{"id":"https://openalex.org/keywords/rhizome","display_name":"rhizome","score":0.8960000276565552},{"id":"https://openalex.org/keywords/phytochemical-constituents","display_name":"phytochemical constituents","score":0.8429999947547913},{"id":"https://openalex.org/keywords/acetylcholinesterase-inhibition","display_name":"acetylcholinesterase inhibition","score":0.9639999866485596},{"id":"https://openalex.org/keywords/phenolic-glycosides","display_name":"phenolic glycosides","score":0.9129999876022339},{"id":"https://openalex.org/keywords/flavones","display_name":"flavones","score":0.972000002861023},{"id":"https://openalex.org/keywords/natural-product-isolation","display_name":"natural product isolation","score":0.6439999938011169},{"id":"https://openalex.org/keywords/structure-elucidation","display_name":"structure elucidation","score":0.9670000076293945}],"concepts":[{"id":"https://openalex.org/C195475562","wikidata":"https://www.wikidata.org/wiki/Q1639139","display_name":"Phytochemical","level":2,"score":0.9251964688301086},{"id":"https://openalex.org/C134550120","wikidata":"https://www.wikidata.org/wiki/Q184208","display_name":"Rhizome","level":2,"score":0.9226570129394531},{"id":"https://openalex.org/C194671627","wikidata":"https://www.wikidata.org/wiki/Q192639","display_name":"Glycoside","level":2,"score":0.6852715015411377},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6673310399055481},{"id":"https://openalex.org/C2778816929","wikidata":"https://www.wikidata.org/wiki/Q22676679","display_name":"Acetylcholinesterase","level":3,"score":0.6481186151504517},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.5841764211654663},{"id":"https://openalex.org/C2776292868","wikidata":"https://www.wikidata.org/wiki/Q424525","display_name":"Flavones","level":2,"score":0.5782116651535034},{"id":"https://openalex.org/C2776789170","wikidata":"https://www.wikidata.org/wiki/Q37021","display_name":"Zingiberaceae","level":3,"score":0.5184726119041443},{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.4492288827896118},{"id":"https://openalex.org/C2779059548","wikidata":"https://www.wikidata.org/wiki/Q383701","display_name":"Ach\u00e9","level":4,"score":0.4292723536491394},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.22062698006629944},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.1852346956729889},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.17640501260757446},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.15692666172981262},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.05861148238182068}],"mesh":[{"descriptor_ui":"D000110","descriptor_name":"Acetylcholinesterase","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D006027","descriptor_name":"Glycosides","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D010936","descriptor_name":"Plant Extracts","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D027343","descriptor_name":"Rhizome","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D030521","descriptor_name":"Zingiberaceae","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D047309","descriptor_name":"Flavones","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1080/14786419.2023.2210738","doi":"https://doi.org/10.1080/14786419.2023.2210738","is_oa":false,"landing_page_url":"https://doi.org/10.1080/14786419.2023.2210738","pdf_url":null,"source":{"id":"https://openalex.org/S205999849","display_name":"Natural Product Research","issn_l":"1478-6419","issn":["1478-6419","1478-6427"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Natural Product Research","raw_type":"journal-article"},{"id":"pmid:37157866","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37157866","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Natural product research","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320323346","display_name":"B\u1ed9 Gi\u00e1o d\u1ee5c v\u00e0 \u00d0\u00e0o t\u1ea1o","ror":"https://ror.org/00drv3378"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":23,"referenced_works":["https://openalex.org/W799686777","https://openalex.org/W1981737231","https://openalex.org/W1986791286","https://openalex.org/W1991880696","https://openalex.org/W1997682149","https://openalex.org/W2013937001","https://openalex.org/W2028435857","https://openalex.org/W2042999911","https://openalex.org/W2057133839","https://openalex.org/W2057167320","https://openalex.org/W2058439383","https://openalex.org/W2067478803","https://openalex.org/W2068335926","https://openalex.org/W2086831494","https://openalex.org/W2087755901","https://openalex.org/W2090776569","https://openalex.org/W2095805909","https://openalex.org/W2151478547","https://openalex.org/W2168294526","https://openalex.org/W2903769441","https://openalex.org/W2952810979","https://openalex.org/W4224287715","https://openalex.org/W4285006439"],"related_works":["https://openalex.org/W1991880696","https://openalex.org/W2932145619","https://openalex.org/W1992339498","https://openalex.org/W2493660034","https://openalex.org/W2013937001","https://openalex.org/W2086831494","https://openalex.org/W2951078142","https://openalex.org/W2605942806","https://openalex.org/W4390710497","https://openalex.org/W7128706953"],"abstract_inverted_index":{"Phytochemical":[0],"study":[1],"on":[2,58],"the":[3,10,30],"rhizomes":[4],"of":[5,12],"Kaempferia":[6],"parviflora":[7],"led":[8],"to":[9,35,78],"isolation":[11],"twenty-three":[13],"compounds":[14,26,32,66],"including":[15],"six":[16],"phenolic":[17,25],"glycosides":[18],"(1-6),":[19],"thirteen":[20],"flavones":[21],"(7-19),":[22],"and":[23,42,46,61],"five":[24],"(20-23).":[27],"Of":[28],"these,":[29],"new":[31],"were":[33,55],"determined":[34],"be":[36],"2,4-dihydroxy-6-methoxyacetophenone-2-\u03b2-D-apiofuranosyl-(1\u21926)-\u03b2-D-glucopyranoside":[37],"(1),":[38],"2-hydroxy-4-propionyl-phenyl":[39],"O-\u03b2-D-glucopyranoside":[40],"(2),":[41],"4-hydroxy-3,5-dimethoxyacetophenone":[43],"8-O-\u03b1-L-rhamnopyranosyl-(1\u21926)-\u03b2-D-glucopyranoside":[44],"(3)":[45],"named":[47],"as":[48],"kaempanosides":[49],"A-C,":[50],"respectively.":[51],"Their":[52],"chemical":[53],"structures":[54],"established":[56],"based":[57],"HR-ESI-MS,":[59],"1D":[60],"2D":[62],"NMR":[63],"spectra.":[64],"All":[65],"1-23":[67],"exhibited":[68],"acetylcholinesterase":[69],"inhibitory":[70],"activity":[71],"with":[72],"IC50":[73],"values":[74],"ranging":[75],"from":[76],"57.76":[77],"253.31":[79],"\u00b5M.":[80]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":2}],"updated_date":"2026-11-03T10:50:19.383937","created_date":"2023-05-10T00:00:00"}