{"id":"https://openalex.org/W4368342972","doi":"https://doi.org/10.1093/ajcp/aqad041","title":"Characterizing the distribution of alterations in mesothelioma and their correlation to morphology","display_name":"Characterizing the distribution of alterations in mesothelioma and their correlation to morphology","publication_year":2023,"publication_date":"2023-05-04","ids":{"openalex":"https://openalex.org/W4368342972","doi":"https://doi.org/10.1093/ajcp/aqad041","pmid":"https://pubmed.ncbi.nlm.nih.gov/37141416"},"language":"en","primary_location":{"id":"doi:10.1093/ajcp/aqad041","doi":"https://doi.org/10.1093/ajcp/aqad041","is_oa":false,"landing_page_url":"https://doi.org/10.1093/ajcp/aqad041","pdf_url":null,"source":{"id":"https://openalex.org/S15871148","display_name":"American Journal of Clinical Pathology","issn_l":"0002-9173","issn":["0002-9173","1943-7722"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Clinical Pathology","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5058364311","display_name":"Heather Chen","orcid":"https://orcid.org/0000-0002-9659-3941","observed_orcids":["https://orcid.org/0000-0002-9659-3941"]},"institutions":[{"id":"https://openalex.org/I4210114445","display_name":"Michigan Medicine","ror":"https://ror.org/01zcpa714","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210114445"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Heather I-Hsuan Chen-Yost","raw_affiliation_strings":["Department of Pathology, Michigan Medicine , Ann Arbor, MI , US"],"raw_orcid":"https://orcid.org/0000-0002-9659-3941","affiliations":[{"raw_affiliation_string":"Department of Pathology, Michigan Medicine , Ann Arbor, MI , US","institution_ids":["https://openalex.org/I4210114445"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069841345","display_name":"Melissa Yuwono Tjota","orcid":"https://orcid.org/0000-0002-5869-3175","observed_orcids":["https://orcid.org/0000-0002-5869-3175"]},"institutions":[{"id":"https://openalex.org/I40347166","display_name":"University of Chicago","ror":"https://ror.org/024mw5h28","country_code":"US","type":"education","lineage":["https://openalex.org/I40347166"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Melissa Y Tjota","raw_affiliation_strings":["Department of Pathology, The University of Chicago Hospitals , Chicago, IL , US"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, The University of Chicago Hospitals , Chicago, IL , US","institution_ids":["https://openalex.org/I40347166"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027048446","display_name":"Guimin Gao","orcid":"https://orcid.org/0000-0001-5556-7141","observed_orcids":["https://orcid.org/0000-0001-5556-7141"]},"institutions":[{"id":"https://openalex.org/I40347166","display_name":"University of Chicago","ror":"https://ror.org/024mw5h28","country_code":"US","type":"education","lineage":["https://openalex.org/I40347166"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Guimin Gao","raw_affiliation_strings":["Department of Public Health Sciences, Biostatistics Laboratory & Research Computing Group, The University of Chicago Hospitals , Chicago, IL , US"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Public Health Sciences, Biostatistics Laboratory & Research Computing Group, The University of Chicago Hospitals , Chicago, IL , US","institution_ids":["https://openalex.org/I40347166"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014068842","display_name":"Owen D. Mitchell","orcid":"https://orcid.org/0000-0001-5601-731X","observed_orcids":["https://orcid.org/0000-0001-5601-731X"]},"institutions":[{"id":"https://openalex.org/I4210087865","display_name":"University of Chicago Medical Center","ror":"https://ror.org/0076kfe04","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087865"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Owen Mitchell","raw_affiliation_strings":["Department of Medicine, The University of Chicago Hospitals , Chicago, IL , US"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, The University of Chicago Hospitals , Chicago, IL , US","institution_ids":["https://openalex.org/I4210087865"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090156519","display_name":"Hedy Lee Kindler","orcid":"https://orcid.org/0000-0002-5450-842X","observed_orcids":["https://orcid.org/0000-0002-5450-842X"]},"institutions":[{"id":"https://openalex.org/I4210087865","display_name":"University of Chicago Medical Center","ror":"https://ror.org/0076kfe04","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087865"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hedy Kindler","raw_affiliation_strings":["Department of Medicine, The University of Chicago Hospitals , Chicago, IL , US"],"raw_orcid":"https://orcid.org/0000-0002-5450-842X","affiliations":[{"raw_affiliation_string":"Department of Medicine, The University of Chicago Hospitals , Chicago, IL , US","institution_ids":["https://openalex.org/I4210087865"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102998623","display_name":"Jeremy P. Segal","orcid":"https://orcid.org/0000-0002-0958-3295","observed_orcids":["https://orcid.org/0000-0002-0958-3295","https://orcid.org/0009-0006-8707-7140"]},"institutions":[{"id":"https://openalex.org/I40347166","display_name":"University of Chicago","ror":"https://ror.org/024mw5h28","country_code":"US","type":"education","lineage":["https://openalex.org/I40347166"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jeremy Segal","raw_affiliation_strings":["Department of Pathology, The University of Chicago Hospitals , Chicago, IL , US"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, The University of Chicago Hospitals , Chicago, IL , US","institution_ids":["https://openalex.org/I40347166"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086195902","display_name":"Aliya Noor Husain","orcid":"https://orcid.org/0000-0001-5492-7387","observed_orcids":["https://orcid.org/0000-0001-5492-7387"]},"institutions":[{"id":"https://openalex.org/I40347166","display_name":"University of Chicago","ror":"https://ror.org/024mw5h28","country_code":"US","type":"education","lineage":["https://openalex.org/I40347166"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Aliya N Husain","raw_affiliation_strings":["Department of Pathology, The University of Chicago Hospitals , Chicago, IL , US"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, The University of Chicago Hospitals , Chicago, IL , US","institution_ids":["https://openalex.org/I40347166"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058846178","display_name":"Jeffrey S. Mueller","orcid":"https://orcid.org/0009-0009-5839-0578","observed_orcids":["https://orcid.org/0009-0009-5839-0578"]},"institutions":[{"id":"https://openalex.org/I40347166","display_name":"University of Chicago","ror":"https://ror.org/024mw5h28","country_code":"US","type":"education","lineage":["https://openalex.org/I40347166"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jeffrey Mueller","raw_affiliation_strings":["Department of Pathology, The University of Chicago Hospitals , Chicago, IL , US"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, The University of Chicago Hospitals , Chicago, IL , US","institution_ids":["https://openalex.org/I40347166"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5057611921","display_name":"Jefree J. Schulte","orcid":"https://orcid.org/0000-0003-3920-0301","observed_orcids":["https://orcid.org/0000-0003-3920-0301"]},"institutions":[{"id":"https://openalex.org/I135310074","display_name":"University of Wisconsin\u2013Madison","ror":"https://ror.org/01y2jtd41","country_code":"US","type":"education","lineage":["https://openalex.org/I135310074"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jefree J Schulte","raw_affiliation_strings":["Department of Pathology and Laboratory Medicine, The University of Wisconsin School of Medicine and Public Health , Madison, WI , US"],"raw_orcid":"https://orcid.org/0000-0003-3920-0301","affiliations":[{"raw_affiliation_string":"Department of Pathology and Laboratory Medicine, The University of Wisconsin School of Medicine and Public Health , Madison, WI , US","institution_ids":["https://openalex.org/I135310074"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5058364311"],"corresponding_institution_ids":["https://openalex.org/I4210114445"],"apc_list":{"value":4440,"currency":"USD","value_usd":4440},"apc_paid":null,"fwci":0.4342,"has_fulltext":false,"cited_by_count":9,"citation_normalized_percentile":{"value":0.41173261,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"160","issue":"3","first_page":"238","last_page":"246"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11026","display_name":"Occupational and environmental lung diseases","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11026","display_name":"Occupational and environmental lung diseases","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12064","display_name":"Intraperitoneal and Appendiceal Malignancies","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10253","display_name":"Sarcoma Diagnosis and Treatment","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mesothelioma","display_name":"mesothelioma","score":0.9860000014305115},{"id":"https://openalex.org/keywords/bap1","display_name":"BAP1","score":0.7990000247955322},{"id":"https://openalex.org/keywords/cdkn2a","display_name":"CDKN2A","score":0.9139999747276306},{"id":"https://openalex.org/keywords/neurofibromatosis-type-2","display_name":"neurofibromatosis type 2","score":0.9990000128746033},{"id":"https://openalex.org/keywords/tp53","display_name":"TP53","score":0.9990000128746033},{"id":"https://openalex.org/keywords/genetic-alterations","display_name":"genetic alterations","score":0.8270000219345093},{"id":"https://openalex.org/keywords/epithelioid-mesothelioma","display_name":"epithelioid mesothelioma","score":0.9480000138282776},{"id":"https://openalex.org/keywords/biphasic-mesothelioma","display_name":"biphasic mesothelioma","score":0.9890000224113464},{"id":"https://openalex.org/keywords/sarcomatoid-mesothelioma","display_name":"sarcomatoid mesothelioma","score":0.996999979019165},{"id":"https://openalex.org/keywords/pleural-mesothelioma","display_name":"pleural mesothelioma","score":0.9409999847412109},{"id":"https://openalex.org/keywords/peritoneal-mesothelioma","display_name":"peritoneal mesothelioma","score":1.0},{"id":"https://openalex.org/keywords/nuclear-grade","display_name":"nuclear grade","score":0.9150000214576721},{"id":"https://openalex.org/keywords/prognosis","display_name":"prognosis","score":0.5529999732971191}],"concepts":[{"id":"https://openalex.org/C2777407522","wikidata":"https://www.wikidata.org/wiki/Q1077603","display_name":"Mesothelioma","level":2,"score":0.9122377634048462},{"id":"https://openalex.org/C37846818","wikidata":"https://www.wikidata.org/wiki/Q18032813","display_name":"BAP1","level":3,"score":0.8973785042762756},{"id":"https://openalex.org/C2776001837","wikidata":"https://www.wikidata.org/wiki/Q9629","display_name":"Peritoneum","level":2,"score":0.780820369720459},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.720365047454834},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5433628559112549},{"id":"https://openalex.org/C2780265364","wikidata":"https://www.wikidata.org/wiki/Q5009957","display_name":"CDKN2A","level":3,"score":0.49294281005859375},{"id":"https://openalex.org/C118441373","wikidata":"https://www.wikidata.org/wiki/Q1347440","display_name":"Epithelioid cell","level":3,"score":0.44811350107192993},{"id":"https://openalex.org/C2778995398","wikidata":"https://www.wikidata.org/wiki/Q7168876","display_name":"Peritoneal mesothelioma","level":3,"score":0.4210923910140991},{"id":"https://openalex.org/C204232928","wikidata":"https://www.wikidata.org/wiki/Q899285","display_name":"Immunohistochemistry","level":2,"score":0.39656373858451843},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.17671766877174377},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.16124886274337769}],"mesh":[{"descriptor_ui":"D000086002","descriptor_name":"Mesothelioma, Malignant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007150","descriptor_name":"Immunohistochemistry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008654","descriptor_name":"Mesothelioma","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D008654","descriptor_name":"Mesothelioma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010997","descriptor_name":"Pleural Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D012509","descriptor_name":"Sarcoma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D025521","descriptor_name":"Tumor Suppressor Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D043222","descriptor_name":"Ubiquitin Thiolesterase","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1093/ajcp/aqad041","doi":"https://doi.org/10.1093/ajcp/aqad041","is_oa":false,"landing_page_url":"https://doi.org/10.1093/ajcp/aqad041","pdf_url":null,"source":{"id":"https://openalex.org/S15871148","display_name":"American Journal of Clinical Pathology","issn_l":"0002-9173","issn":["0002-9173","1943-7722"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Clinical Pathology","raw_type":"journal-article"},{"id":"pmid:37141416","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37141416","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American journal of clinical pathology","raw_type":"Review"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.98580002784729,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":46,"referenced_works":["https://openalex.org/W67716143","https://openalex.org/W1153405174","https://openalex.org/W1659637636","https://openalex.org/W1987045640","https://openalex.org/W1989762654","https://openalex.org/W2007116705","https://openalex.org/W2061242666","https://openalex.org/W2094290949","https://openalex.org/W2110934295","https://openalex.org/W2112394495","https://openalex.org/W2136470067","https://openalex.org/W2155228850","https://openalex.org/W2197124825","https://openalex.org/W2291531085","https://openalex.org/W2329699996","https://openalex.org/W2402154519","https://openalex.org/W2460247111","https://openalex.org/W2532073344","https://openalex.org/W2539000115","https://openalex.org/W2546458812","https://openalex.org/W2552027239","https://openalex.org/W2621539987","https://openalex.org/W2745276752","https://openalex.org/W2755733485","https://openalex.org/W2769074301","https://openalex.org/W2773000470","https://openalex.org/W2783573668","https://openalex.org/W2799601627","https://openalex.org/W2801632358","https://openalex.org/W2802627246","https://openalex.org/W2837873388","https://openalex.org/W2888761405","https://openalex.org/W2889469922","https://openalex.org/W2897299514","https://openalex.org/W2897943350","https://openalex.org/W2899052879","https://openalex.org/W2938922501","https://openalex.org/W2940817974","https://openalex.org/W2952513725","https://openalex.org/W2964746205","https://openalex.org/W2974545606","https://openalex.org/W2997728035","https://openalex.org/W3007024906","https://openalex.org/W3033124927","https://openalex.org/W3087637892","https://openalex.org/W3093000805"],"related_works":["https://openalex.org/W4406121461","https://openalex.org/W3206427587","https://openalex.org/W4296793422","https://openalex.org/W4221044007","https://openalex.org/W2504398253","https://openalex.org/W2546458812","https://openalex.org/W3032043348","https://openalex.org/W3201468575","https://openalex.org/W3169689508","https://openalex.org/W2460336842"],"abstract_inverted_index":{"OBJECTIVES:":[0],"Mesothelioma":[1],"is":[2,42],"a":[3,144,268,276],"lethal":[4],"disease":[5],"that":[6,59],"arises":[7],"from":[8,99,105],"the":[9,91,94,100,106,153,155,176,187,199,233,259],"serosal":[10],"lining":[11],"of":[12,114,157,189,232,258],"organ":[13],"cavities.":[14],"Several":[15],"recurrent":[16],"alterations":[17,49,130,197,243],"have":[18,36],"been":[19,37],"observed":[20],"in":[21,27,90,133,152,160,175,192,198,222,248,282],"pleural":[22],"and":[23,30,79,86,102,119,137,195,238,245,279],"peritoneal":[24],"-mesotheliomas,":[25],"including":[26],"BAP1,":[28,134],"NF2,":[29,136],"CDKN2A.":[31],"Although":[32],"specific":[33],"histopathologic":[34],"parameters":[35],"correlated":[38,162],"with":[39,51,163,213,219,241,275],"prognosis,":[40],"it":[41],"not":[43,142],"as":[44],"well":[45],"known":[46],"whether":[47],"genetic":[48],"correlate":[50],"histologic":[52],"findings.":[53],"METHODS:":[54],"We":[55],"reviewed":[56],"131":[57],"mesotheliomas":[58,140,151,194,240],"had":[60],"undergone":[61],"next-generation":[62],"sequencing":[63],"(NGS)":[64],"at":[65],"our":[66,84],"institutions":[67],"after":[68],"pathologic":[69],"diagnosis.":[70],"There":[71],"were":[72,98,104,111,132,224,250],"109":[73],"epithelioid":[74,95,150,193,229],"mesotheliomas,":[75,78,96,211],"18":[76],"biphasic":[77,85,210,239],"4":[80],"sarcomatoid":[81,87,255],"mesotheliomas.":[82],"All":[83],"cases":[88,212],"arose":[89],"pleura.":[92],"Of":[93],"73":[97],"pleura":[101,200],"36":[103],"peritoneum.":[107],"On":[108],"average,":[109],"patients":[110],"66":[112],"years":[113],"age":[115],"(range,":[116],"26-90":[117],"years)":[118],"predominantly":[120],"male":[121],"(92":[122],"men,":[123],"39":[124],"women).":[125],"RESULTS:":[126],"The":[127],"most":[128],"common":[129],"identified":[131],"CDKN2A,":[135],"TP53.":[138],"Twelve":[139],"did":[141],"show":[143],"pathogenic":[145],"alteration":[146,159,216,221,247,281],"on":[147],"NGS.":[148],"For":[149,209],"pleura,":[154],"presence":[156],"an":[158,220,280],"BAP1":[161,223,249],"low":[164],"nuclear":[165],"grade":[166],"(P":[167,178,201,206],"=":[168,179,202,207,236,262],".04),":[169],"but":[170],"no":[171,184,215,246],"correlation":[172,185],"was":[173,183],"found":[174],"peritoneum":[177,205],".62).":[180],"Similarly,":[181],"there":[182],"between":[186,271],"amount":[188],"solid":[190],"architecture":[191],"any":[196],".55)":[203],"or":[204,218],".13).":[208],"either":[214],"detected":[217,244],"more":[225,251],"likely":[226,252],"to":[227,253],"be":[228,254],"predominant":[230,256],"(>50%":[231,257],"tumor,":[234,260],"P":[235,261],".0001),":[237],"other":[242],".0001).":[263],"CONCLUSIONS:":[264],"This":[265],"study":[266],"demonstrates":[267],"significant":[269],"association":[270],"morphologic":[272],"features":[273],"associated":[274],"better":[277],"prognosis":[278],"BAP1.":[283]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2023-05-05T00:00:00"}
