{"id":"https://openalex.org/W4367668714","doi":"https://doi.org/10.1002/mas.21847","title":"Effects of charge on protein ion structure: Lessons from cation\u2010to\u2010anion, proton\u2010transfer reactions","display_name":"Effects of charge on protein ion structure: Lessons from cation\u2010to\u2010anion, proton\u2010transfer reactions","publication_year":2023,"publication_date":"2023-05-02","ids":{"openalex":"https://openalex.org/W4367668714","doi":"https://doi.org/10.1002/mas.21847","pmid":"https://pubmed.ncbi.nlm.nih.gov/37129026"},"language":"en","primary_location":{"id":"doi:10.1002/mas.21847","doi":"https://doi.org/10.1002/mas.21847","is_oa":false,"landing_page_url":"https://doi.org/10.1002/mas.21847","pdf_url":null,"source":{"id":"https://openalex.org/S69764086","display_name":"Mass Spectrometry Reviews","issn_l":"0277-7037","issn":["0277-7037","1098-2787"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mass Spectrometry Reviews","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5003778233","display_name":"Theresa A. Gozzo","orcid":"https://orcid.org/0009-0002-4498-2483","observed_orcids":["https://orcid.org/0009-0002-4498-2483"]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Theresa A. Gozzo","raw_affiliation_strings":["Department of Chemistry, University of Washington, Seattle, Washington, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, University of Washington, Seattle, Washington, USA","institution_ids":["https://openalex.org/I201448701"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5025760162","display_name":"Matthew F. Bush","orcid":"https://orcid.org/0000-0003-3526-4973","observed_orcids":["https://orcid.org/0000-0003-3526-4973"]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Matthew F. Bush","raw_affiliation_strings":["Department of Chemistry, University of Washington, Seattle, Washington, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, University of Washington, Seattle, Washington, USA","institution_ids":["https://openalex.org/I201448701"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5025760162"],"corresponding_institution_ids":["https://openalex.org/I201448701"],"apc_list":{"value":4740,"currency":"USD","value_usd":4740},"apc_paid":null,"fwci":0.4541,"has_fulltext":false,"cited_by_count":15,"citation_normalized_percentile":{"value":0.41565217,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":99},"biblio":{"volume":"43","issue":"3","first_page":"500","last_page":"525"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10683","display_name":"Mass Spectrometry Techniques and Applications","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10683","display_name":"Mass Spectrometry Techniques and Applications","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10519","display_name":"Advanced Proteomics Techniques and Applications","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/charge-state","display_name":"charge states","score":0.6639999747276306},{"id":"https://openalex.org/keywords/collision-cross-sections","display_name":"collision cross sections","score":0.9390000104904175},{"id":"https://openalex.org/keywords/ion-mobility","display_name":"ion mobility","score":0.5920000076293945},{"id":"https://openalex.org/keywords/collisional-activation","display_name":"collisional activation","score":0.7229999899864197}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.8997952938079834},{"id":"https://openalex.org/C145148216","wikidata":"https://www.wikidata.org/wiki/Q36496","display_name":"Ion","level":2,"score":0.8335790634155273},{"id":"https://openalex.org/C54516573","wikidata":"https://www.wikidata.org/wiki/Q2294","display_name":"Proton","level":2,"score":0.6460511684417725},{"id":"https://openalex.org/C188082385","wikidata":"https://www.wikidata.org/wiki/Q73792","display_name":"Charge (physics)","level":2,"score":0.6353580951690674},{"id":"https://openalex.org/C162356407","wikidata":"https://www.wikidata.org/wiki/Q180809","display_name":"Mass spectrometry","level":2,"score":0.5565339922904968},{"id":"https://openalex.org/C159467904","wikidata":"https://www.wikidata.org/wiki/Q2001702","display_name":"Chemical physics","level":1,"score":0.545975387096405},{"id":"https://openalex.org/C15213710","wikidata":"https://www.wikidata.org/wiki/Q904207","display_name":"Ion-mobility spectrometry","level":3,"score":0.5338332056999207},{"id":"https://openalex.org/C39984356","wikidata":"https://www.wikidata.org/wiki/Q2121987","display_name":"Quadrupole","level":2,"score":0.4768858253955841},{"id":"https://openalex.org/C53323650","wikidata":"https://www.wikidata.org/wiki/Q1118362","display_name":"Proton affinity","level":4,"score":0.46465128660202026},{"id":"https://openalex.org/C184779094","wikidata":"https://www.wikidata.org/wiki/Q26383","display_name":"Atomic physics","level":1,"score":0.37747547030448914},{"id":"https://openalex.org/C147597530","wikidata":"https://www.wikidata.org/wiki/Q369472","display_name":"Computational chemistry","level":1,"score":0.37621235847473145},{"id":"https://openalex.org/C113196181","wikidata":"https://www.wikidata.org/wiki/Q485223","display_name":"Analytical Chemistry (journal)","level":2,"score":0.33266979455947876},{"id":"https://openalex.org/C185544564","wikidata":"https://www.wikidata.org/wiki/Q81197","display_name":"Nuclear physics","level":1,"score":0.11383318901062012},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.07449483871459961},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.061761319637298584},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C30095370","wikidata":"https://www.wikidata.org/wiki/Q899488","display_name":"Protonation","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D000838","descriptor_name":"Anions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002412","descriptor_name":"Cations","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D007477","descriptor_name":"Ions","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011522","descriptor_name":"Protons","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D013058","descriptor_name":"Mass Spectrometry","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1002/mas.21847","doi":"https://doi.org/10.1002/mas.21847","is_oa":false,"landing_page_url":"https://doi.org/10.1002/mas.21847","pdf_url":null,"source":{"id":"https://openalex.org/S69764086","display_name":"Mass Spectrometry Reviews","issn_l":"0277-7037","issn":["0277-7037","1098-2787"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mass Spectrometry Reviews","raw_type":"journal-article"},{"id":"pmid:37129026","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37129026","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mass spectrometry reviews","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":114,"referenced_works":["https://openalex.org/W112108890","https://openalex.org/W640055744","https://openalex.org/W1665864650","https://openalex.org/W1778581172","https://openalex.org/W1965984884","https://openalex.org/W1970471856","https://openalex.org/W1971346042","https://openalex.org/W1974196671","https://openalex.org/W1977249043","https://openalex.org/W1977593844","https://openalex.org/W1977628837","https://openalex.org/W1979500244","https://openalex.org/W1983826454","https://openalex.org/W1984951342","https://openalex.org/W1986676950","https://openalex.org/W1987081570","https://openalex.org/W1991642366","https://openalex.org/W1991998914","https://openalex.org/W1992276902","https://openalex.org/W1993774961","https://openalex.org/W1994517844","https://openalex.org/W1998785079","https://openalex.org/W1999365897","https://openalex.org/W1999694861","https://openalex.org/W2000819512","https://openalex.org/W2003569986","https://openalex.org/W2005919833","https://openalex.org/W2012453070","https://openalex.org/W2013608848","https://openalex.org/W2015007795","https://openalex.org/W2016670512","https://openalex.org/W2018871138","https://openalex.org/W2020743949","https://openalex.org/W2022354632","https://openalex.org/W2022501859","https://openalex.org/W2026555049","https://openalex.org/W2032883396","https://openalex.org/W2036529877","https://openalex.org/W2036734090","https://openalex.org/W2040119231","https://openalex.org/W2043902364","https://openalex.org/W2045177392","https://openalex.org/W2049112325","https://openalex.org/W2053407332","https://openalex.org/W2054083856","https://openalex.org/W2054838229","https://openalex.org/W2062765492","https://openalex.org/W2065544983","https://openalex.org/W2065843920","https://openalex.org/W2070698810","https://openalex.org/W2071498033","https://openalex.org/W2072391178","https://openalex.org/W2074901150","https://openalex.org/W2075941490","https://openalex.org/W2078729456","https://openalex.org/W2080279644","https://openalex.org/W2089214055","https://openalex.org/W2089321562","https://openalex.org/W2090943942","https://openalex.org/W2092729964","https://openalex.org/W2101821801","https://openalex.org/W2104026577","https://openalex.org/W2112763744","https://openalex.org/W2114442129","https://openalex.org/W2115588498","https://openalex.org/W2121612064","https://openalex.org/W2123911097","https://openalex.org/W2131741443","https://openalex.org/W2144787267","https://openalex.org/W2149789639","https://openalex.org/W2160659542","https://openalex.org/W2165561713","https://openalex.org/W2167687898","https://openalex.org/W2169656611","https://openalex.org/W2170846952","https://openalex.org/W2226503394","https://openalex.org/W2300161746","https://openalex.org/W2315295879","https://openalex.org/W2316249707","https://openalex.org/W2317233863","https://openalex.org/W2325380571","https://openalex.org/W2333112136","https://openalex.org/W2408391104","https://openalex.org/W2460127275","https://openalex.org/W2460236151","https://openalex.org/W2463867582","https://openalex.org/W2488798338","https://openalex.org/W2507630532","https://openalex.org/W2511978382","https://openalex.org/W2591442792","https://openalex.org/W2597237296","https://openalex.org/W2625648671","https://openalex.org/W2709490442","https://openalex.org/W2772936471","https://openalex.org/W2806811536","https://openalex.org/W2897867571","https://openalex.org/W2913182573","https://openalex.org/W2921404852","https://openalex.org/W2949320474","https://openalex.org/W2959837251","https://openalex.org/W2981493160","https://openalex.org/W3005204542","https://openalex.org/W3015885311","https://openalex.org/W3028736644","https://openalex.org/W3042556306","https://openalex.org/W3127209578","https://openalex.org/W4207068619","https://openalex.org/W4221086849","https://openalex.org/W4295754977","https://openalex.org/W6606375942","https://openalex.org/W6609329690","https://openalex.org/W6639704412","https://openalex.org/W6813946517","https://openalex.org/W6817554161"],"related_works":["https://openalex.org/W2709490442","https://openalex.org/W2591442792","https://openalex.org/W2897867571","https://openalex.org/W2072391178","https://openalex.org/W2755632562","https://openalex.org/W2597237296","https://openalex.org/W2611330315","https://openalex.org/W1491574842","https://openalex.org/W2094938467","https://openalex.org/W2530352216"],"abstract_inverted_index":{"Collision":[0],"cross-section":[1,39],"values,":[2,40],"which":[3],"can":[4,34],"be":[5],"determined":[6],"using":[7,80],"ion":[8,84,118],"mobility":[9],"experiments,":[10,105],"are":[11,78],"sensitive":[12],"to":[13,23,94,109],"the":[14,100,114],"structures":[15],"of":[16,45,63,83,102,113],"protein":[17,65,117],"ions":[18,29],"and":[19,26,88,98,120],"useful":[20],"for":[21,59],"applications":[22],"structural":[24],"biology":[25],"biophysics.":[27],"Protein":[28],"with":[30,71],"different":[31,37],"charge":[32,121],"states":[33],"exhibit":[35],"very":[36],"collision":[38],"but":[41],"a":[42,57,61,81,110],"comprehensive":[43],"understanding":[44,112],"this":[46],"relationship":[47,115],"remains":[48],"elusive.":[49],"Here,":[50],"we":[51],"review":[52,99],"cation-to-anion,":[53],"proton-transfer":[54],"reactions":[55],"(CAPTR),":[56],"method":[58],"generating":[60],"series":[62],"charge-reduced":[64],"cations":[66,70],"by":[67],"reacting":[68],"quadrupole-selected":[69],"even-electron":[72],"monoanions.":[73],"The":[74],"resulting":[75],"CAPTR":[76,93],"products":[77],"analyzed":[79],"combination":[82],"mobility,":[85],"mass":[86],"spectrometry,":[87],"collisional":[89],"activation.":[90],"We":[91],"compare":[92],"other":[95],"charge-manipulation":[96],"strategies":[97],"results":[101],"various":[103],"CAPTR-based":[104],"exploring":[106],"their":[107],"contribution":[108],"deeper":[111],"between":[116],"structure":[119],"state.":[122]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":7},{"year":2023,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2023-05-03T00:00:00"}
