{"id":"https://openalex.org/W4367668253","doi":"https://doi.org/10.1111/dgd.12852","title":"Molecular functions of the double\u2010sided and inverted ubiquitin\u2010interacting motif found in Xenopus tropicalis cryptochrome 6","display_name":"Molecular functions of the double\u2010sided and inverted ubiquitin\u2010interacting motif found in Xenopus tropicalis cryptochrome 6","publication_year":2023,"publication_date":"2023-05-01","ids":{"openalex":"https://openalex.org/W4367668253","doi":"https://doi.org/10.1111/dgd.12852","pmid":"https://pubmed.ncbi.nlm.nih.gov/37127930","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/11520951"},"language":"en","primary_location":{"id":"doi:10.1111/dgd.12852","doi":"https://doi.org/10.1111/dgd.12852","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1111/dgd.12852","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/dgd.12852","source":{"id":"https://openalex.org/S103234284","display_name":"Development Growth & Differentiation","issn_l":"0012-1592","issn":["0012-1592","1440-169X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Development, Growth & Differentiation","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/dgd.12852","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5103435110","display_name":"Keiko Okano","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I150744194","display_name":"Waseda University","ror":"https://ror.org/00ntfnx83","country_code":"JP","type":"education","lineage":["https://openalex.org/I150744194"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Keiko Okano","raw_affiliation_strings":["Department of Electrical Engineering and Bioscience, Graduate School of Sciences and Engineering Waseda University, TWIns  Tokyo Japan","Department of Electrical Engineering and Bioscience, Graduate School of Sciences and Engineering, Waseda University, TWIns, Wakamatsucho 2-2, Shinjuku-Ku, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Electrical Engineering and Bioscience, Graduate School of Sciences and Engineering Waseda University, TWIns  Tokyo Japan","institution_ids":["https://openalex.org/I150744194"]},{"raw_affiliation_string":"Department of Electrical Engineering and Bioscience, Graduate School of Sciences and Engineering, Waseda University, TWIns, Wakamatsucho 2-2, Shinjuku-Ku, Tokyo, Japan","institution_ids":["https://openalex.org/I150744194"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056590384","display_name":"Hiroaki Otsuka","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I150744194","display_name":"Waseda University","ror":"https://ror.org/00ntfnx83","country_code":"JP","type":"education","lineage":["https://openalex.org/I150744194"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hiroaki Otsuka","raw_affiliation_strings":["Department of Electrical Engineering and Bioscience, Graduate School of Sciences and Engineering Waseda University, TWIns  Tokyo Japan","Department of Electrical Engineering and Bioscience, Graduate School of Sciences and Engineering, Waseda University, TWIns, Wakamatsucho 2-2, Shinjuku-Ku, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Electrical Engineering and Bioscience, Graduate School of Sciences and Engineering Waseda University, TWIns  Tokyo Japan","institution_ids":["https://openalex.org/I150744194"]},{"raw_affiliation_string":"Department of Electrical Engineering and Bioscience, Graduate School of Sciences and Engineering, Waseda University, TWIns, Wakamatsucho 2-2, Shinjuku-Ku, Tokyo, Japan","institution_ids":["https://openalex.org/I150744194"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020835682","display_name":"Marika Nakagawa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I150744194","display_name":"Waseda University","ror":"https://ror.org/00ntfnx83","country_code":"JP","type":"education","lineage":["https://openalex.org/I150744194"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Marika Nakagawa","raw_affiliation_strings":["Department of Electrical Engineering and Bioscience, Graduate School of Sciences and Engineering Waseda University, TWIns  Tokyo Japan","Department of Electrical Engineering and Bioscience, Graduate School of Sciences and Engineering, Waseda University, TWIns, Wakamatsucho 2-2, Shinjuku-Ku, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Electrical Engineering and Bioscience, Graduate School of Sciences and Engineering Waseda University, TWIns  Tokyo Japan","institution_ids":["https://openalex.org/I150744194"]},{"raw_affiliation_string":"Department of Electrical Engineering and Bioscience, Graduate School of Sciences and Engineering, Waseda University, TWIns, Wakamatsucho 2-2, Shinjuku-Ku, Tokyo, Japan","institution_ids":["https://openalex.org/I150744194"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5027618404","display_name":"Toshiyuki Okano","orcid":"https://orcid.org/0000-0001-6740-6265","observed_orcids":["https://orcid.org/0000-0001-6740-6265"]},"institutions":[{"id":"https://openalex.org/I150744194","display_name":"Waseda University","ror":"https://ror.org/00ntfnx83","country_code":"JP","type":"education","lineage":["https://openalex.org/I150744194"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Toshiyuki Okano","raw_affiliation_strings":["Department of Electrical Engineering and Bioscience, Graduate School of Sciences and Engineering Waseda University, TWIns  Tokyo Japan","Department of Electrical Engineering and Bioscience, Graduate School of Sciences and Engineering, Waseda University, TWIns, Wakamatsucho 2-2, Shinjuku-Ku, Tokyo, Japan"],"raw_orcid":"https://orcid.org/0000-0001-6740-6265","affiliations":[{"raw_affiliation_string":"Department of Electrical Engineering and Bioscience, Graduate School of Sciences and Engineering Waseda University, TWIns  Tokyo Japan","institution_ids":["https://openalex.org/I150744194"]},{"raw_affiliation_string":"Department of Electrical Engineering and Bioscience, Graduate School of Sciences and Engineering, Waseda University, TWIns, Wakamatsucho 2-2, Shinjuku-Ku, Tokyo, Japan","institution_ids":["https://openalex.org/I150744194"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5027618404"],"corresponding_institution_ids":["https://openalex.org/I150744194"],"apc_list":{"value":3800,"currency":"USD","value_usd":3800},"apc_paid":{"value":3800,"currency":"USD","value_usd":3800},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.05537701,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"65","issue":"4","first_page":"203","last_page":"214"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10342","display_name":"Circadian rhythm and melatonin","score":0.9868000149726868,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10342","display_name":"Circadian rhythm and melatonin","score":0.9868000149726868,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11268","display_name":"Light effects on plants","score":0.004000000189989805,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11041","display_name":"Ubiquitin and proteasome pathways","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/xenopus-tropicalis","display_name":"Xenopus tropicalis","score":0.921999990940094},{"id":"https://openalex.org/keywords/ubiquitin-interacting-motif","display_name":"ubiquitin-interacting motif","score":0.8679999709129333},{"id":"https://openalex.org/keywords/nucleolar-localization","display_name":"nucleolar localization","score":0.6669999957084656},{"id":"https://openalex.org/keywords/circadian-clock","display_name":"circadian clock","score":0.8169999718666077},{"id":"https://openalex.org/keywords/blue-light-photoreception","display_name":"blue light photoreception","score":0.7789999842643738},{"id":"https://openalex.org/keywords/protein-docking","display_name":"protein docking","score":0.39899998903274536}],"concepts":[{"id":"https://openalex.org/C144543706","wikidata":"https://www.wikidata.org/wiki/Q85754737","display_name":"Cryptochrome","level":4,"score":0.8353664875030518},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6790357232093811},{"id":"https://openalex.org/C186435350","wikidata":"https://www.wikidata.org/wiki/Q1050365","display_name":"NLS","level":4,"score":0.6421905755996704},{"id":"https://openalex.org/C25602115","wikidata":"https://www.wikidata.org/wiki/Q407111","display_name":"Ubiquitin","level":3,"score":0.595277726650238},{"id":"https://openalex.org/C134459356","wikidata":"https://www.wikidata.org/wiki/Q4274835","display_name":"Ubiquitin ligase","level":4,"score":0.5746642351150513},{"id":"https://openalex.org/C2779535977","wikidata":"https://www.wikidata.org/wiki/Q1342298","display_name":"Xenopus","level":3,"score":0.5463748574256897},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.45214352011680603},{"id":"https://openalex.org/C49805395","wikidata":"https://www.wikidata.org/wiki/Q910966","display_name":"Nuclear localization sequence","level":3,"score":0.44292616844177246},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.4418566823005676},{"id":"https://openalex.org/C123894998","wikidata":"https://www.wikidata.org/wiki/Q425158","display_name":"Fusion protein","level":4,"score":0.4395483434200287},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.3940108120441437},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.321727991104126},{"id":"https://openalex.org/C38606739","wikidata":"https://www.wikidata.org/wiki/Q5121352","display_name":"Circadian clock","level":3,"score":0.2678977847099304},{"id":"https://openalex.org/C40767141","wikidata":"https://www.wikidata.org/wiki/Q285697","display_name":"Recombinant DNA","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014981","descriptor_name":"Xenopus","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014981","descriptor_name":"Xenopus","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D025801","descriptor_name":"Ubiquitin","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D025801","descriptor_name":"Ubiquitin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D056931","descriptor_name":"Cryptochromes","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D056931","descriptor_name":"Cryptochromes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D057809","descriptor_name":"HEK293 Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1111/dgd.12852","doi":"https://doi.org/10.1111/dgd.12852","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1111/dgd.12852","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/dgd.12852","source":{"id":"https://openalex.org/S103234284","display_name":"Development Growth & Differentiation","issn_l":"0012-1592","issn":["0012-1592","1440-169X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Development, Growth & Differentiation","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:11520951","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11520951","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11520951/pdf/DGD-65-203.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Dev Growth Differ","raw_type":"Text"},{"id":"pmid:37127930","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37127930","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Development, growth & differentiation","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1111/dgd.12852","doi":"https://doi.org/10.1111/dgd.12852","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1111/dgd.12852","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/dgd.12852","source":{"id":"https://openalex.org/S103234284","display_name":"Development Growth & Differentiation","issn_l":"0012-1592","issn":["0012-1592","1440-169X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Development, Growth & Differentiation","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G3903172426","display_name":"Establishment of a model cell to study photoresponsive mechanisms to moonlight","funder_award_id":"18K19348","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G81274568","display_name":null,"funder_award_id":"JPMXS01 20330644","funder_id":"https://openalex.org/F4320320912","funder_display_name":"Ministry of Education, Culture, Sports, Science and Technology"}],"funders":[{"id":"https://openalex.org/F4320320912","display_name":"Ministry of Education, Culture, Sports, Science and Technology","ror":"https://ror.org/048rj2z13"},{"id":"https://openalex.org/F4320322638","display_name":"Waseda University","ror":"https://ror.org/00ntfnx83"},{"id":"https://openalex.org/F4320334764","display_name":"Japan Society for the Promotion of Science","ror":"https://ror.org/00hhkn466"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4367668253.pdf","grobid_xml":"https://content.openalex.org/works/W4367668253.grobid-xml"},"referenced_works_count":32,"referenced_works":["https://openalex.org/W1974637570","https://openalex.org/W1982671296","https://openalex.org/W2003847336","https://openalex.org/W2006114349","https://openalex.org/W2009139105","https://openalex.org/W2015161511","https://openalex.org/W2019845267","https://openalex.org/W2043816782","https://openalex.org/W2049327347","https://openalex.org/W2055390996","https://openalex.org/W2056775476","https://openalex.org/W2078067969","https://openalex.org/W2085672451","https://openalex.org/W2094232417","https://openalex.org/W2103238897","https://openalex.org/W2130349018","https://openalex.org/W2135216170","https://openalex.org/W2142196823","https://openalex.org/W2152868594","https://openalex.org/W2154491135","https://openalex.org/W2155721813","https://openalex.org/W2493982139","https://openalex.org/W2555317369","https://openalex.org/W2605702032","https://openalex.org/W2781607775","https://openalex.org/W2949525645","https://openalex.org/W2979577982","https://openalex.org/W3011171402","https://openalex.org/W3085115859","https://openalex.org/W3160131590","https://openalex.org/W4210757594","https://openalex.org/W4231612575"],"related_works":["https://openalex.org/W2141667212","https://openalex.org/W2062830884","https://openalex.org/W2103138287","https://openalex.org/W7126476152","https://openalex.org/W1997885966","https://openalex.org/W1987956257","https://openalex.org/W2060763368","https://openalex.org/W2079467858","https://openalex.org/W2069492032","https://openalex.org/W4243958574"],"abstract_inverted_index":{"Cryptochromes":[0],"(CRYs)":[1],"are":[2,22],"multifunctional":[3],"molecules":[4,185],"that":[5,70,85,167,179,209,220],"act":[6],"as":[7,44,214,227],"a":[8,13,17,51,60,90,106,112,187,190,215,238],"circadian":[9,216],"clock":[10],"oscillating":[11],"factor,":[12],"blue-light":[14],"sensor,":[15],"and":[16,40,46,101,105,117,128,219],"light-driven":[18],"magnetoreceptor.":[19],"Cry":[20],"genes":[21],"classified":[23],"into":[24],"several":[25],"groups":[26],"based":[27],"on":[28],"the":[29,78,126,134,151,158,168,195,202,245],"evolutionary":[30],"relationships.":[31],"Cryptochrome":[32],"6":[33],"gene":[34,235],"(Cry6)":[35],"is":[36,71],"present":[37],"in":[38,54,74,77,144,150,157,186,244],"invertebrates":[39],"lower":[41],"vertebrates":[42],"such":[43,226],"amphibians":[45],"fishes.":[47],"Here":[48],"we":[49],"identified":[50],"Cry6":[52],"ortholog":[53],"Xenopus":[55],"tropicalis":[56],"(XtCry6).":[57],"XtCRY6":[58,180,210],"retains":[59],"conserved":[61],"long":[62],"N-terminal":[63,67],"extension":[64],"(termed":[65,109],"CRY":[66,76],"extension;":[68],"CNE)":[69],"not":[72,212],"found":[73],"any":[75],"other":[79],"groups.":[80],"A":[81,160],"structural":[82],"prediction":[83],"suggested":[84,166,208],"CNE":[86],"contained":[87],"unique":[88],"structures;":[89],"tetrahelical":[91],"fold":[92],"structure":[93],"topologically":[94],"related":[95],"to":[96,132,201],"KaiA/RbsU":[97],"domain,":[98],"overlapping":[99,111],"nuclear-":[100],"nucleolar-localizing":[102],"signals":[103],"(NLS/NoLS),":[104],"novel":[107],"motif":[108,115,121],"DI-UIM)":[110],"double-sided":[113],"ubiquitin-interacting":[114,120],"(DUIM)":[116],"an":[118],"inverted":[119],"(IUIM).":[122],"Potential":[123],"activities":[124],"of":[125,137,189],"NLS/NoLS":[127],"DI-UIM":[129,169,181,203],"were":[130],"examined":[131],"infer":[133],"molecular":[135],"function":[136,213,225],"XtCRY6.":[138],"GFP-NLS/NoLS":[139],"fusion":[140],"protein":[141,175,232],"exogenously":[142],"expressed":[143],"HEK293":[145],"cells":[146],"was":[147,155],"mostly":[148],"observed":[149,156],"nucleolus,":[152],"while":[153],"GFP-XtCRY6":[154],"cytoplasm.":[159],"glutathione":[161],"S-transferase":[162],"(GST)":[163],"pull-down":[164],"assay":[165],"physically":[170],"interacts":[171],"with":[172,194,241],"polyubiquitin.":[173],"Consistently,":[174],"docking":[176],"simulations":[177],"implied":[178],"binds":[182],"two":[183],"ubiquitin":[184],"relationship":[188],"twofold":[191],"rotational":[192],"symmetry":[193,196],"axis":[197],"parallel":[198],"or":[199,234],"perpendicular":[200],"helix.":[204],"These":[205],"results":[206],"strongly":[207],"does":[211],"transcriptional":[217],"repressor":[218],"it":[221],"might":[222],"have":[223],"another":[224],"photoreceptive":[228],"molecule":[229],"regulating":[230],"light-dependent":[231],"degradation":[233],"expression":[236],"through":[237],"CNE-mediated":[239],"interaction":[240],"ubiquitinated":[242],"proteins":[243],"cytoplasm":[246],"and/or":[247],"nucleolus.":[248]},"counts_by_year":[],"updated_date":"2026-11-03T10:50:19.383937","created_date":"2023-05-03T00:00:00"}