{"id":"https://openalex.org/W4367603698","doi":"https://doi.org/10.1158/2643-3230.22725567","title":"Supplementary Table S6 from In Vivo Screening Unveils Pervasive RNA-Binding Protein Dependencies in Leukemic Stem Cells and Identifies ELAVL1 as a Therapeutic Target","display_name":"Supplementary Table S6 from In Vivo Screening Unveils Pervasive RNA-Binding Protein Dependencies in Leukemic Stem Cells and Identifies ELAVL1 as a Therapeutic Target","publication_year":2023,"publication_date":"2023-05-01","ids":{"openalex":"https://openalex.org/W4367603698","doi":"https://doi.org/10.1158/2643-3230.22725567"},"language":"en","primary_location":{"id":"doi:10.1158/2643-3230.22725567","doi":"https://doi.org/10.1158/2643-3230.22725567","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1158/2643-3230.22725567","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"volume":null,"type":"supplementary-materials","is_traditional":false,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"http://dx.doi.org/10.1158/2643-3230.22725567","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5018963738","display_name":"Ana Vujovic","orcid":"https://orcid.org/0000-0002-9117-9282","observed_orcids":["https://orcid.org/0000-0002-9117-9282"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ana Vujovic","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-9117-9282","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091378750","display_name":"Laura P. M. H. de Rooij","orcid":"https://orcid.org/0000-0002-1810-4620","observed_orcids":["https://orcid.org/0000-0002-1810-4620"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Laura de Rooij","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-1810-4620","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036378829","display_name":"Ava Keyvani Chahi","orcid":"https://orcid.org/0000-0001-7554-5839","observed_orcids":["https://orcid.org/0000-0001-7554-5839"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ava Keyvani Chahi","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-7554-5839","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043437338","display_name":"He Tian Chen","orcid":"https://orcid.org/0000-0001-8233-7448","observed_orcids":["https://orcid.org/0000-0001-8233-7448"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"He Tian Chen","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-8233-7448","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044573289","display_name":"Brian A. Yee","orcid":"https://orcid.org/0000-0001-5615-8550","observed_orcids":["https://orcid.org/0000-0001-5615-8550"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Brian A. Yee","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-5615-8550","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080981389","display_name":"Sampath K. Loganathan","orcid":"https://orcid.org/0000-0002-8809-1466","observed_orcids":["https://orcid.org/0000-0002-8809-1466"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sampath K. Loganathan","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-8809-1466","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077166553","display_name":"Lina Liu","orcid":"https://orcid.org/0000-0001-5537-6353","observed_orcids":["https://orcid.org/0000-0001-5537-6353"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Lina Liu","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-5537-6353","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074275528","display_name":"Derek C.H. Chan","orcid":"https://orcid.org/0000-0003-4086-5108","observed_orcids":["https://orcid.org/0000-0003-4086-5108"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Derek C.H. Chan","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-4086-5108","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048493645","display_name":"Amanda Tajik","orcid":"https://orcid.org/0000-0003-2674-844X","observed_orcids":["https://orcid.org/0000-0003-2674-844X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Amanda Tajik","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-2674-844X","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030409150","display_name":"Emily Tsao","orcid":"https://orcid.org/0000-0002-2269-618X","observed_orcids":["https://orcid.org/0000-0002-2269-618X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Emily Tsao","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-2269-618X","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076374247","display_name":"Steven Moreira","orcid":"https://orcid.org/0000-0003-3350-2093","observed_orcids":["https://orcid.org/0000-0003-3350-2093"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Steven Moreira","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-3350-2093","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041678802","display_name":"Pratik Joshi","orcid":"https://orcid.org/0000-0002-8206-9823","observed_orcids":["https://orcid.org/0000-0002-8206-9823"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Pratik Joshi","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-8206-9823","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054428689","display_name":"Joshua Xu","orcid":"https://orcid.org/0000-0001-8318-5669","observed_orcids":["https://orcid.org/0000-0001-8318-5669"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Joshua Xu","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-8318-5669","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078622643","display_name":"Nicholas Wong","orcid":"https://orcid.org/0000-0002-2831-2415","observed_orcids":["https://orcid.org/0000-0002-2831-2415"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Nicholas Wong","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-2831-2415","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040694519","display_name":"Zaldy Balde","orcid":"https://orcid.org/0000-0002-5820-7130","observed_orcids":["https://orcid.org/0000-0002-5820-7130","https://orcid.org/0009-0001-7954-5745"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Zaldy Balde","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-5820-7130","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112907193","display_name":"Soheil Jahangiri","orcid":"https://orcid.org/0000-0002-3772-792X","observed_orcids":["https://orcid.org/0000-0002-3772-792X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Soheil Jahangiri","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-3772-792X","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020461005","display_name":"Sasan Zandi","orcid":"https://orcid.org/0000-0002-8448-094X","observed_orcids":["https://orcid.org/0000-0002-8448-094X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sasan Zandi","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-8448-094X","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077600290","display_name":"Stefan Aigner","orcid":"https://orcid.org/0000-0002-9511-3328","observed_orcids":["https://orcid.org/0000-0002-9511-3328"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Stefan Aigner","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-9511-3328","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090356933","display_name":"John Edgar Dick","orcid":"https://orcid.org/0000-0002-9527-8317","observed_orcids":["https://orcid.org/0000-0002-9527-8317"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"John E. Dick","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-9527-8317","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026397928","display_name":"Mark David Minden","orcid":"https://orcid.org/0000-0002-9089-8816","observed_orcids":["https://orcid.org/0000-0002-9089-8816"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mark D. Minden","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-9089-8816","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026022573","display_name":"Daniel Schramek","orcid":"https://orcid.org/0000-0001-9977-2104","observed_orcids":["https://orcid.org/0000-0001-9977-2104"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Daniel Schramek","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-9977-2104","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082310752","display_name":"Gene Wei-Ming Yeo","orcid":"https://orcid.org/0000-0002-0799-6037","observed_orcids":["https://orcid.org/0000-0002-0799-6037"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Gene W. Yeo","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-0799-6037","affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5076562420","display_name":"Kristin J. Hope","orcid":"https://orcid.org/0000-0003-1449-4948","observed_orcids":["https://orcid.org/0000-0003-1449-4948"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kristin J. Hope","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-1449-4948","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":0.9390000104904175,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":0.9390000104904175,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10309","display_name":"Acute Myeloid Leukemia Research","score":0.011800000444054604,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10345","display_name":"Hematopoietic Stem Cell Transplantation","score":0.003000000026077032,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hur","display_name":"HuR","score":0.9779999852180481},{"id":"https://openalex.org/keywords/rna-binding-proteins","display_name":"RNA-binding proteins","score":0.8159999847412109},{"id":"https://openalex.org/keywords/leukemia-stem-cells","display_name":"leukemia stem cells","score":0.9419999718666077},{"id":"https://openalex.org/keywords/gene-set-enrichment-analysis","display_name":"gene set enrichment analysis","score":0.6690000295639038},{"id":"https://openalex.org/keywords/therapeutic-target","display_name":"therapeutic target","score":0.574999988079071},{"id":"https://openalex.org/keywords/leukemia","display_name":"leukemia","score":0.4399999976158142}],"concepts":[{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.6615161895751953},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.5416032075881958},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.48259007930755615},{"id":"https://openalex.org/C45235069","wikidata":"https://www.wikidata.org/wiki/Q278425","display_name":"Table (database)","level":2,"score":0.48079127073287964},{"id":"https://openalex.org/C41282012","wikidata":"https://www.wikidata.org/wiki/Q3928341","display_name":"RNA-binding protein","level":4,"score":0.45268335938453674},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.42186999320983887},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.41016942262649536},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.40896859765052795},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.3911451995372772},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.24507778882980347},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2331305742263794},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.14883294701576233},{"id":"https://openalex.org/C77088390","wikidata":"https://www.wikidata.org/wiki/Q8513","display_name":"Database","level":1,"score":0.11508634686470032}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1158/2643-3230.22725567","doi":"https://doi.org/10.1158/2643-3230.22725567","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1158/2643-3230.22725567","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},{"id":"doi:10.1158/2643-3230.22725567.v1","doi":"https://doi.org/10.1158/2643-3230.22725567.v1","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1158/2643-3230.22725567.v1","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},{"id":"pmh:oai:figshare.com:article/22725567","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/dataset/Supplementary_Table_S6_from_i_In_Vivo_i_Screening_Unveils_Pervasive_RNA-Binding_Protein_Dependencies_in_Leukemic_Stem_Cells_and_Identifies_ELAVL1_as_a_Therapeutic_Target/22725567","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dataset"}],"best_oa_location":{"id":"doi:10.1158/2643-3230.22725567","doi":"https://doi.org/10.1158/2643-3230.22725567","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1158/2643-3230.22725567","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"sustainable_development_goals":[{"score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":[],"abstract_inverted_index":{"Table":[0],"S6":[1],"shows":[2],"altered":[3],"gene":[4],"sets":[5],"identified":[6],"by":[7],"GSEA":[8],"of":[9],"the":[10],"ELAVL1":[11],"knockout":[12],"RN2c":[13],"RNA-sequencing":[14],"data":[15],"set.":[16]},"counts_by_year":[],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2023-05-02T00:00:00"}