{"id":"https://openalex.org/W4367599707","doi":"https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a2361","title":"Regional Pulmonary Vascular Resistance (PVR) Beyond the Lungs' Total: A Proof-of-Concept PET Imaging Study of Regional PVR in Pulmonary Arterial Hypertension (PAH) at Baseline and During Inhaled NO","display_name":"Regional Pulmonary Vascular Resistance (PVR) Beyond the Lungs' Total: A Proof-of-Concept PET Imaging Study of Regional PVR in Pulmonary Arterial Hypertension (PAH) at Baseline and During Inhaled NO","publication_year":2023,"publication_date":"2023-05-01","ids":{"openalex":"https://openalex.org/W4367599707","doi":"https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a2361"},"language":"en","primary_location":{"id":"doi:10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a2361","doi":"https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a2361","is_oa":false,"landing_page_url":"http://dx.doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a2361","pdf_url":null,"source":{"id":"https://openalex.org/S93356601","display_name":"American Journal of Respiratory and Critical Care Medicine","issn_l":"1073-449X","issn":["1073-449X","1535-4970"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310316311","host_organization_name":"American Thoracic Society","host_organization_lineage":["https://openalex.org/P4310316311"],"host_organization_lineage_names":["American Thoracic Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"A71. MATTERS OF THE HEART...AND LUNGS: STUDIES ON CARDIOPULMONARY VASCULAR DISEASE","raw_type":"proceedings-article"},"volume":null,"type":"conference-abstract","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5085792559","display_name":"Tilo Winkler","orcid":"https://orcid.org/0000-0002-7276-5550","observed_orcids":["https://orcid.org/0000-0002-7276-5550"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"T. Winkler","raw_affiliation_strings":["Dept of Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dept of Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101789409","display_name":"Puja Kohli","orcid":"https://orcid.org/0000-0002-3967-3136","observed_orcids":["https://orcid.org/0000-0002-3967-3136"]},"institutions":[{"id":"https://openalex.org/I61970326","display_name":"Vertex Pharmaceuticals (United States)","ror":"https://ror.org/00anb1726","country_code":"US","type":"company","lineage":["https://openalex.org/I61970326"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"P. Kohli","raw_affiliation_strings":["Vertex Pharmaceuticals, Boston, MA, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Vertex Pharmaceuticals, Boston, MA, United States","institution_ids":["https://openalex.org/I61970326"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023904129","display_name":"Vanessa J. Kelly","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210125181","display_name":"Invicro (United States)","ror":"https://ror.org/039cbfe54","country_code":"US","type":"company","lineage":["https://openalex.org/I4210125181"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"V.J. Kelly","raw_affiliation_strings":["inviCRO, Boston, MA, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"inviCRO, Boston, MA, United States","institution_ids":["https://openalex.org/I4210125181"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007032545","display_name":"Ekaterina G. Kehl","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1297058315","display_name":"Mount Auburn Hospital","ror":"https://ror.org/00nhpk003","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1297058315"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"E.G. Kehl","raw_affiliation_strings":["Division of Pulmonary and Critical Care Medicine, Mount Auburn Hospital and Harvard Medical School, Cambridge, MA, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Pulmonary and Critical Care Medicine, Mount Auburn Hospital and Harvard Medical School, Cambridge, MA, United States","institution_ids":["https://openalex.org/I1297058315","https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053901854","display_name":"M. Kone","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M. Kone","raw_affiliation_strings":["Pulmonary and Critical Care, Massachusetts General Hospiital, Boston, MA, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pulmonary and Critical Care, Massachusetts General Hospiital, Boston, MA, United States","institution_ids":["https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049770571","display_name":"Alison S. Witkin","orcid":"https://orcid.org/0000-0002-4650-2116","observed_orcids":["https://orcid.org/0000-0002-4650-2116"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"A.S. Witkin","raw_affiliation_strings":["Pulmonary and Critical Care, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pulmonary and Critical Care, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054712760","display_name":"Kathryn Anne Hibbert","orcid":"https://orcid.org/0000-0001-7908-5446","observed_orcids":["https://orcid.org/0000-0001-7908-5446"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"K.A. Hibbert","raw_affiliation_strings":["Pulmonary and Critical Care, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pulmonary and Critical Care, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063372789","display_name":"Josanna Rodriguez\u2010Lopez","orcid":"https://orcid.org/0000-0003-2637-0563","observed_orcids":["https://orcid.org/0000-0003-2637-0563"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J.M. Rodriguez-Lopez","raw_affiliation_strings":["Pulmonary and Critical Care, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pulmonary and Critical Care, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109489460","display_name":"David Systrom","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"D.M. Systrom","raw_affiliation_strings":["Pulmonary and Critical Care, Brigham & Women's Hospital and Harvard Medical School, Boston, MA, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pulmonary and Critical Care, Brigham & Women's Hospital and Harvard Medical School, Boston, MA, United States","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021150751","display_name":"Aaron B. Waxman","orcid":"https://orcid.org/0000-0001-7797-0361","observed_orcids":["https://orcid.org/0000-0001-7797-0361"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"A.B. Waxman","raw_affiliation_strings":["Pulmonary and Critical Care, Brigham & Women's Hospital and Harvard Medical School, Boston, MA, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pulmonary and Critical Care, Brigham & Women's Hospital and Harvard Medical School, Boston, MA, United States","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112075636","display_name":"JG Venegas","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J.G. Venegas","raw_affiliation_strings":["Dept of Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dept of Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068539599","display_name":"Richard N. Channick","orcid":"https://orcid.org/0000-0002-9016-4468","observed_orcids":["https://orcid.org/0000-0002-9016-4468"]},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"R.N. Channick","raw_affiliation_strings":["Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, United States","institution_ids":["https://openalex.org/I161318765"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5056467598","display_name":"R. Scott Harris","orcid":"https://orcid.org/0000-0002-2684-6202","observed_orcids":["https://orcid.org/0000-0002-2684-6202"]},"institutions":[{"id":"https://openalex.org/I61970326","display_name":"Vertex Pharmaceuticals (United States)","ror":"https://ror.org/00anb1726","country_code":"US","type":"company","lineage":["https://openalex.org/I61970326"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"R.S. Harris","raw_affiliation_strings":["Vertex Pharmaceuticals, Boston, MA, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Vertex Pharmaceuticals, Boston, MA, United States","institution_ids":["https://openalex.org/I61970326"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"A2361","last_page":"A2361"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10728","display_name":"Pulmonary Hypertension Research and Treatments","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10728","display_name":"Pulmonary Hypertension Research and Treatments","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12199","display_name":"Vascular Anomalies and Treatments","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10372","display_name":"Cardiac Imaging and Diagnostics","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pulmonary-arterial-hypertension","display_name":"pulmonary arterial hypertension","score":0.9940000176429749},{"id":"https://openalex.org/keywords/inhaled-nitric-oxide","display_name":"inhaled nitric oxide","score":0.9520000219345093},{"id":"https://openalex.org/keywords/positron-emission-tomography","display_name":"positron emission tomography","score":0.7400000095367432},{"id":"https://openalex.org/keywords/pulmonary-circulation","display_name":"pulmonary circulation","score":0.48399999737739563},{"id":"https://openalex.org/keywords/pulmonary-vascular-resistance","display_name":"pulmonary vascular resistance","score":0.3100000023841858}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7030718326568604},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.6250280141830444},{"id":"https://openalex.org/C58245268","wikidata":"https://www.wikidata.org/wiki/Q456026","display_name":"Vascular resistance","level":3,"score":0.6088932156562805},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5884381532669067},{"id":"https://openalex.org/C2780930700","wikidata":"https://www.wikidata.org/wiki/Q1128595","display_name":"Pulmonary hypertension","level":2,"score":0.4951225817203522},{"id":"https://openalex.org/C12725497","wikidata":"https://www.wikidata.org/wiki/Q810247","display_name":"Baseline (sea)","level":2,"score":0.4845408499240875},{"id":"https://openalex.org/C178853913","wikidata":"https://www.wikidata.org/wiki/Q1642137","display_name":"Hemodynamics","level":2,"score":0.1809893548488617},{"id":"https://openalex.org/C17744445","wikidata":"https://www.wikidata.org/wiki/Q36442","display_name":"Political science","level":0,"score":0.05717968940734863},{"id":"https://openalex.org/C199539241","wikidata":"https://www.wikidata.org/wiki/Q7748","display_name":"Law","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a2361","doi":"https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a2361","is_oa":false,"landing_page_url":"http://dx.doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a2361","pdf_url":null,"source":{"id":"https://openalex.org/S93356601","display_name":"American Journal of Respiratory and Critical Care Medicine","issn_l":"1073-449X","issn":["1073-449X","1535-4970"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310316311","host_organization_name":"American Thoracic Society","host_organization_lineage":["https://openalex.org/P4310316311"],"host_organization_lineage_names":["American Thoracic Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"A71. MATTERS OF THE HEART...AND LUNGS: STUDIES ON CARDIOPULMONARY VASCULAR DISEASE","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W3041978971","https://openalex.org/W1562054789","https://openalex.org/W170969514","https://openalex.org/W2003907424","https://openalex.org/W2045636084","https://openalex.org/W4310494067","https://openalex.org/W2117241330","https://openalex.org/W2078067641","https://openalex.org/W2794555049","https://openalex.org/W4232474259"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-11-02T09:45:03.842371","created_date":"2023-05-02T00:00:00"}