{"id":"https://openalex.org/W4367596777","doi":"https://doi.org/10.1016/j.tcb.2023.03.009","title":"Mitochondria in cancer stem cells: Achilles heel or hard armor","display_name":"Mitochondria in cancer stem cells: Achilles heel or hard armor","publication_year":2023,"publication_date":"2023-05-01","ids":{"openalex":"https://openalex.org/W4367596777","doi":"https://doi.org/10.1016/j.tcb.2023.03.009","pmid":"https://pubmed.ncbi.nlm.nih.gov/37137792"},"language":"en","primary_location":{"id":"doi:10.1016/j.tcb.2023.03.009","doi":"https://doi.org/10.1016/j.tcb.2023.03.009","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.tcb.2023.03.009","pdf_url":null,"source":{"id":"https://openalex.org/S118628157","display_name":"Trends in Cell Biology","issn_l":"0962-8924","issn":["0962-8924","1879-3088"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Trends in Cell Biology","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100573693","display_name":"Xiaoxia Zheng","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I151075929","display_name":"Army Medical University","ror":"https://ror.org/05w21nn13","country_code":"CN","type":"education","lineage":["https://openalex.org/I151075929"]},{"id":"https://openalex.org/I4210131174","display_name":"Southwest Hospital","ror":"https://ror.org/02jn36537","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210131174"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiao-xia Zheng","raw_affiliation_strings":["Department of Stem Cell and Regenerative Medicine, Institute of Pathology and Southwest Cancer Center, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing 400038, China; International Joint Research Center for Precision Biotherapy, Ministry of Science and Technology, Chongqing 400038, China; Key Laboratory of Cancer Immunopathology, Ministry of Education, Chongqing 400038, China","Department of Stem Cell and Regenerative Medicine, Institute of Pathology and Southwest Cancer Center, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing 400038, China","International Joint Research Center for Precision Biotherapy, Ministry of Science and Technology, Chongqing 400038, China","Key Laboratory of Cancer Immunopathology, Ministry of Education, Chongqing 400038, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Stem Cell and Regenerative Medicine, Institute of Pathology and Southwest Cancer Center, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing 400038, China; International Joint Research Center for Precision Biotherapy, Ministry of Science and Technology, Chongqing 400038, China; Key Laboratory of Cancer Immunopathology, Ministry of Education, Chongqing 400038, China","institution_ids":["https://openalex.org/I151075929","https://openalex.org/I4210131174"]},{"raw_affiliation_string":"Department of Stem Cell and Regenerative Medicine, Institute of Pathology and Southwest Cancer Center, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing 400038, China","institution_ids":["https://openalex.org/I151075929","https://openalex.org/I4210131174"]},{"raw_affiliation_string":"International Joint Research Center for Precision Biotherapy, Ministry of Science and Technology, Chongqing 400038, China","institution_ids":[]},{"raw_affiliation_string":"Key Laboratory of Cancer Immunopathology, Ministry of Education, Chongqing 400038, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100365539","display_name":"Junjie Chen","orcid":"https://orcid.org/0000-0002-1493-2189","observed_orcids":["https://orcid.org/0000-0002-1493-2189"]},"institutions":[{"id":"https://openalex.org/I151075929","display_name":"Army Medical University","ror":"https://ror.org/05w21nn13","country_code":"CN","type":"education","lineage":["https://openalex.org/I151075929"]},{"id":"https://openalex.org/I4210131174","display_name":"Southwest Hospital","ror":"https://ror.org/02jn36537","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210131174"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jun-jie Chen","raw_affiliation_strings":["Department of Stem Cell and Regenerative Medicine, Institute of Pathology and Southwest Cancer Center, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing 400038, China; International Joint Research Center for Precision Biotherapy, Ministry of Science and Technology, Chongqing 400038, China; Key Laboratory of Cancer Immunopathology, Ministry of Education, Chongqing 400038, China","Department of Stem Cell and Regenerative Medicine, Institute of Pathology and Southwest Cancer Center, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing 400038, China","International Joint Research Center for Precision Biotherapy, Ministry of Science and Technology, Chongqing 400038, China","Key Laboratory of Cancer Immunopathology, Ministry of Education, Chongqing 400038, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Stem Cell and Regenerative Medicine, Institute of Pathology and Southwest Cancer Center, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing 400038, China; International Joint Research Center for Precision Biotherapy, Ministry of Science and Technology, Chongqing 400038, China; Key Laboratory of Cancer Immunopathology, Ministry of Education, Chongqing 400038, China","institution_ids":["https://openalex.org/I151075929","https://openalex.org/I4210131174"]},{"raw_affiliation_string":"Department of Stem Cell and Regenerative Medicine, Institute of Pathology and Southwest Cancer Center, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing 400038, China","institution_ids":["https://openalex.org/I151075929","https://openalex.org/I4210131174"]},{"raw_affiliation_string":"International Joint Research Center for Precision Biotherapy, Ministry of Science and Technology, Chongqing 400038, China","institution_ids":[]},{"raw_affiliation_string":"Key Laboratory of Cancer Immunopathology, Ministry of Education, Chongqing 400038, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Yi-bo Sun","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I151075929","display_name":"Army Medical University","ror":"https://ror.org/05w21nn13","country_code":"CN","type":"education","lineage":["https://openalex.org/I151075929"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yi-bo Sun","raw_affiliation_strings":["College of Basic Medical Sciences, Third Military Medical University (Army Medical University), Chongqing 400038, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Basic Medical Sciences, Third Military Medical University (Army Medical University), Chongqing 400038, China","institution_ids":["https://openalex.org/I151075929"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089861197","display_name":"Tian-qing Chen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I17721919","display_name":"Shanxi Medical University","ror":"https://ror.org/0265d1010","country_code":"CN","type":"education","lineage":["https://openalex.org/I17721919"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Tian-qing Chen","raw_affiliation_strings":["School of Pharmacy, Shanxi Medical University, Taiyuan, 030002, Shanxi, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Pharmacy, Shanxi Medical University, Taiyuan, 030002, Shanxi, China","institution_ids":["https://openalex.org/I17721919"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100384635","display_name":"Jun Wang","orcid":"https://orcid.org/0000-0001-8437-3055","observed_orcids":["https://orcid.org/0000-0001-8437-3055"]},"institutions":[{"id":"https://openalex.org/I151075929","display_name":"Army Medical University","ror":"https://ror.org/05w21nn13","country_code":"CN","type":"education","lineage":["https://openalex.org/I151075929"]},{"id":"https://openalex.org/I4210131174","display_name":"Southwest Hospital","ror":"https://ror.org/02jn36537","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210131174"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jun Wang","raw_affiliation_strings":["Department of Stem Cell and Regenerative Medicine, Institute of Pathology and Southwest Cancer Center, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing 400038, China; International Joint Research Center for Precision Biotherapy, Ministry of Science and Technology, Chongqing 400038, China; Key Laboratory of Cancer Immunopathology, Ministry of Education, Chongqing 400038, China","Department of Stem Cell and Regenerative Medicine, Institute of Pathology and Southwest Cancer Center, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing 400038, China","International Joint Research Center for Precision Biotherapy, Ministry of Science and Technology, Chongqing 400038, China","Key Laboratory of Cancer Immunopathology, Ministry of Education, Chongqing 400038, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Stem Cell and Regenerative Medicine, Institute of Pathology and Southwest Cancer Center, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing 400038, China; International Joint Research Center for Precision Biotherapy, Ministry of Science and Technology, Chongqing 400038, China; Key Laboratory of Cancer Immunopathology, Ministry of Education, Chongqing 400038, China","institution_ids":["https://openalex.org/I151075929","https://openalex.org/I4210131174"]},{"raw_affiliation_string":"Department of Stem Cell and Regenerative Medicine, Institute of Pathology and Southwest Cancer Center, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing 400038, China","institution_ids":["https://openalex.org/I151075929","https://openalex.org/I4210131174"]},{"raw_affiliation_string":"International Joint Research Center for Precision Biotherapy, Ministry of Science and Technology, Chongqing 400038, China","institution_ids":[]},{"raw_affiliation_string":"Key Laboratory of Cancer Immunopathology, Ministry of Education, Chongqing 400038, China","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100676919","display_name":"Shi\u2010Cang Yu","orcid":"https://orcid.org/0000-0001-6151-1224","observed_orcids":["https://orcid.org/0000-0001-6151-1224"]},"institutions":[{"id":"https://openalex.org/I151075929","display_name":"Army Medical University","ror":"https://ror.org/05w21nn13","country_code":"CN","type":"education","lineage":["https://openalex.org/I151075929"]},{"id":"https://openalex.org/I4210131174","display_name":"Southwest Hospital","ror":"https://ror.org/02jn36537","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210131174"]},{"id":"https://openalex.org/I4405260818","display_name":"Jinfeng Laboratory","ror":"https://ror.org/04amdcz96","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4405260818"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Shi-cang Yu","raw_affiliation_strings":["Department of Stem Cell and Regenerative Medicine, Institute of Pathology and Southwest Cancer Center, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing 400038, China; International Joint Research Center for Precision Biotherapy, Ministry of Science and Technology, Chongqing 400038, China; Key Laboratory of Cancer Immunopathology, Ministry of Education, Chongqing 400038, China; College of Basic Medical Sciences, Third Military Medical University (Army Medical University), Chongqing 400038, China; Jin-feng Laboratory, Chongqing 401329, China. Electronic address: yushicang@163.com","College of Basic Medical Sciences, Third Military Medical University (Army Medical University), Chongqing 400038, China","Department of Stem Cell and Regenerative Medicine, Institute of Pathology and Southwest Cancer Center, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing 400038, China","International Joint Research Center for Precision Biotherapy, Ministry of Science and Technology, Chongqing 400038, China","Jin-feng Laboratory, Chongqing 401329, China","Key Laboratory of Cancer Immunopathology, Ministry of Education, Chongqing 400038, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Stem Cell and Regenerative Medicine, Institute of Pathology and Southwest Cancer Center, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing 400038, China; International Joint Research Center for Precision Biotherapy, Ministry of Science and Technology, Chongqing 400038, China; Key Laboratory of Cancer Immunopathology, Ministry of Education, Chongqing 400038, China; College of Basic Medical Sciences, Third Military Medical University (Army Medical University), Chongqing 400038, China; Jin-feng Laboratory, Chongqing 401329, China. Electronic address: yushicang@163.com","institution_ids":["https://openalex.org/I151075929","https://openalex.org/I4210131174","https://openalex.org/I4405260818"]},{"raw_affiliation_string":"College of Basic Medical Sciences, Third Military Medical University (Army Medical University), Chongqing 400038, China","institution_ids":["https://openalex.org/I151075929"]},{"raw_affiliation_string":"Department of Stem Cell and Regenerative Medicine, Institute of Pathology and Southwest Cancer Center, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing 400038, China","institution_ids":["https://openalex.org/I151075929","https://openalex.org/I4210131174"]},{"raw_affiliation_string":"International Joint Research Center for Precision Biotherapy, Ministry of Science and Technology, Chongqing 400038, China","institution_ids":[]},{"raw_affiliation_string":"Jin-feng Laboratory, Chongqing 401329, China","institution_ids":["https://openalex.org/I4405260818"]},{"raw_affiliation_string":"Key Laboratory of Cancer Immunopathology, Ministry of Education, Chongqing 400038, China","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5100676919"],"corresponding_institution_ids":["https://openalex.org/I151075929","https://openalex.org/I4210131174","https://openalex.org/I4405260818"],"apc_list":{"value":6830,"currency":"USD","value_usd":6830},"apc_paid":null,"fwci":2.231,"has_fulltext":false,"cited_by_count":69,"citation_normalized_percentile":{"value":0.91861377,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":98,"max":100},"biblio":{"volume":"33","issue":"8","first_page":"708","last_page":"727"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10336","display_name":"Cancer Cells and Metastasis","score":0.5551999807357788,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10336","display_name":"Cancer Cells and Metastasis","score":0.5551999807357788,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10631","display_name":"Cancer, Hypoxia, and Metabolism","score":0.1736000031232834,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10301","display_name":"Mitochondrial Function and Pathology","score":0.11540000140666962,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mitochondria","display_name":"mitochondria","score":0.9290000200271606},{"id":"https://openalex.org/keywords/cancer-stem-cells","display_name":"cancer stem cells","score":1.0},{"id":"https://openalex.org/keywords/stemness-maintenance","display_name":"stemness maintenance","score":0.9039999842643738},{"id":"https://openalex.org/keywords/metabolic-reprogramming","display_name":"metabolic reprogramming","score":0.7689999938011169},{"id":"https://openalex.org/keywords/chemoresistance","display_name":"chemoresistance","score":0.9729999899864197},{"id":"https://openalex.org/keywords/mitochondrial-dna","display_name":"mitochondrial DNA","score":0.746999979019165},{"id":"https://openalex.org/keywords/mitochondrial-metabolism","display_name":"mitochondrial metabolism","score":0.777999997138977},{"id":"https://openalex.org/keywords/mitophagy","display_name":"mitophagy","score":0.9660000205039978},{"id":"https://openalex.org/keywords/mitochondria-targeted-drugs","display_name":"mitochondria-targeted drugs","score":0.859000027179718},{"id":"https://openalex.org/keywords/csc-targeted-therapy","display_name":"CSC-targeted therapy","score":0.7179999947547913}],"concepts":[{"id":"https://openalex.org/C2779324830","wikidata":"https://www.wikidata.org/wiki/Q1806192","display_name":"Mitophagy","level":4,"score":0.819909393787384},{"id":"https://openalex.org/C28859421","wikidata":"https://www.wikidata.org/wiki/Q39572","display_name":"Mitochondrion","level":2,"score":0.8172646760940552},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8065486550331116},{"id":"https://openalex.org/C55427017","wikidata":"https://www.wikidata.org/wiki/Q1638475","display_name":"Cancer stem cell","level":3,"score":0.6878847479820251},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5843473672866821},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.5472400784492493},{"id":"https://openalex.org/C96232424","wikidata":"https://www.wikidata.org/wiki/Q4118072","display_name":"Cancer cell","level":3,"score":0.4972701370716095},{"id":"https://openalex.org/C89611455","wikidata":"https://www.wikidata.org/wiki/Q6804646","display_name":"Mechanism (biology)","level":2,"score":0.4958859384059906},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.47142189741134644},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.42119163274765015},{"id":"https://openalex.org/C203522944","wikidata":"https://www.wikidata.org/wiki/Q288322","display_name":"Autophagy","level":3,"score":0.40966930985450745},{"id":"https://openalex.org/C190283241","wikidata":"https://www.wikidata.org/wiki/Q14599311","display_name":"Apoptosis","level":2,"score":0.1417456865310669},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.13776329159736633},{"id":"https://openalex.org/C111472728","wikidata":"https://www.wikidata.org/wiki/Q9471","display_name":"Epistemology","level":1,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D004272","descriptor_name":"DNA, Mitochondrial","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008928","descriptor_name":"Mitochondria","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D008928","descriptor_name":"Mitochondria","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008928","descriptor_name":"Mitochondria","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D014411","descriptor_name":"Neoplastic Stem Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D014411","descriptor_name":"Neoplastic Stem Cells","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":true},{"descriptor_ui":"D019008","descriptor_name":"Drug Resistance, Neoplasm","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D063306","descriptor_name":"Mitophagy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.tcb.2023.03.009","doi":"https://doi.org/10.1016/j.tcb.2023.03.009","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.tcb.2023.03.009","pdf_url":null,"source":{"id":"https://openalex.org/S118628157","display_name":"Trends in Cell Biology","issn_l":"0962-8924","issn":["0962-8924","1879-3088"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Trends in Cell Biology","raw_type":"journal-article"},{"id":"pmid:37137792","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37137792","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Trends in cell biology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.98580002784729,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":112,"referenced_works":["https://openalex.org/W1409804080","https://openalex.org/W1573010401","https://openalex.org/W1590478199","https://openalex.org/W1707356941","https://openalex.org/W1823151161","https://openalex.org/W1839791560","https://openalex.org/W1883840806","https://openalex.org/W1892036645","https://openalex.org/W1897724420","https://openalex.org/W1906647682","https://openalex.org/W1987907150","https://openalex.org/W1997982747","https://openalex.org/W2010559315","https://openalex.org/W2012152282","https://openalex.org/W2014509406","https://openalex.org/W2023300506","https://openalex.org/W2025636927","https://openalex.org/W2026579395","https://openalex.org/W2028303721","https://openalex.org/W2035564874","https://openalex.org/W2052319461","https://openalex.org/W2056146179","https://openalex.org/W2057139407","https://openalex.org/W2059009119","https://openalex.org/W2059613997","https://openalex.org/W2066346185","https://openalex.org/W2069809499","https://openalex.org/W2074617654","https://openalex.org/W2081410358","https://openalex.org/W2085955424","https://openalex.org/W2092909753","https://openalex.org/W2107883924","https://openalex.org/W2116319147","https://openalex.org/W2119094880","https://openalex.org/W2130503287","https://openalex.org/W2134150856","https://openalex.org/W2159864138","https://openalex.org/W2184058368","https://openalex.org/W2304994032","https://openalex.org/W2322816935","https://openalex.org/W2412718576","https://openalex.org/W2415427537","https://openalex.org/W2480725775","https://openalex.org/W2517130978","https://openalex.org/W2552838557","https://openalex.org/W2558729727","https://openalex.org/W2572807235","https://openalex.org/W2605309684","https://openalex.org/W2617805631","https://openalex.org/W2739375529","https://openalex.org/W2755975022","https://openalex.org/W2756196902","https://openalex.org/W2761556050","https://openalex.org/W2765546718","https://openalex.org/W2770706758","https://openalex.org/W2771691812","https://openalex.org/W2785955818","https://openalex.org/W2792151102","https://openalex.org/W2797799943","https://openalex.org/W2806128074","https://openalex.org/W2808682367","https://openalex.org/W2809576672","https://openalex.org/W2885929148","https://openalex.org/W2894467698","https://openalex.org/W2897148138","https://openalex.org/W2898243895","https://openalex.org/W2901480442","https://openalex.org/W2907897113","https://openalex.org/W2909546334","https://openalex.org/W2911357126","https://openalex.org/W2914661118","https://openalex.org/W2914948262","https://openalex.org/W2922955951","https://openalex.org/W2945886392","https://openalex.org/W2947639189","https://openalex.org/W2964186349","https://openalex.org/W2965561098","https://openalex.org/W2971385210","https://openalex.org/W2981532221","https://openalex.org/W2982216374","https://openalex.org/W2982979216","https://openalex.org/W2990858141","https://openalex.org/W2993495616","https://openalex.org/W3004733773","https://openalex.org/W3028175184","https://openalex.org/W3028827854","https://openalex.org/W3045450469","https://openalex.org/W3090943432","https://openalex.org/W3092769144","https://openalex.org/W3095331736","https://openalex.org/W3111855896","https://openalex.org/W3113178272","https://openalex.org/W3116504395","https://openalex.org/W3119256114","https://openalex.org/W3124206276","https://openalex.org/W3125076999","https://openalex.org/W3128417170","https://openalex.org/W3130039072","https://openalex.org/W3134167221","https://openalex.org/W3156283008","https://openalex.org/W3164891644","https://openalex.org/W3189075912","https://openalex.org/W3199718997","https://openalex.org/W3200811637","https://openalex.org/W3215945617","https://openalex.org/W3217537082","https://openalex.org/W4212803254","https://openalex.org/W4243903519","https://openalex.org/W4294133290","https://openalex.org/W4308558942","https://openalex.org/W6726772974","https://openalex.org/W6801380198"],"related_works":["https://openalex.org/W2901480442","https://openalex.org/W7139910131","https://openalex.org/W2734085570","https://openalex.org/W2025786070","https://openalex.org/W4411980982","https://openalex.org/W3042300848","https://openalex.org/W2149137517","https://openalex.org/W4414107779","https://openalex.org/W3126985924","https://openalex.org/W3102965684"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":18},{"year":2025,"cited_by_count":31},{"year":2024,"cited_by_count":13},{"year":2023,"cited_by_count":7}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2023-05-02T00:00:00"}