{"id":"https://openalex.org/W4367550232","doi":"https://doi.org/10.1128/jvi.00209-23","title":"Generation of Human Embryonic Stem Cell-Derived Lung Organoids for Modeling Infection and Replication Differences between Human Adenovirus Types 3 and 55 and Evaluating Potential Antiviral Drugs","display_name":"Generation of Human Embryonic Stem Cell-Derived Lung Organoids for Modeling Infection and Replication Differences between Human Adenovirus Types 3 and 55 and Evaluating Potential Antiviral Drugs","publication_year":2023,"publication_date":"2023-04-30","ids":{"openalex":"https://openalex.org/W4367550232","doi":"https://doi.org/10.1128/jvi.00209-23","pmid":"https://pubmed.ncbi.nlm.nih.gov/37120831","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/10231139"},"language":"en","primary_location":{"id":"doi:10.1128/jvi.00209-23","doi":"https://doi.org/10.1128/jvi.00209-23","is_oa":true,"landing_page_url":"https://doi.org/10.1128/jvi.00209-23","pdf_url":"https://journals.asm.org/doi/pdf/10.1128/jvi.00209-23?download=true","source":{"id":"https://openalex.org/S96615428","display_name":"Journal of Virology","issn_l":"0022-538X","issn":["0022-538X","1070-6321","1098-5514"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Virology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://journals.asm.org/doi/pdf/10.1128/jvi.00209-23?download=true","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101844192","display_name":"Shanshan Zhao","orcid":"https://orcid.org/0000-0003-2690-0624","observed_orcids":["https://orcid.org/0000-0003-2690-0624"]},"institutions":[{"id":"https://openalex.org/I58200834","display_name":"Southern Medical University","ror":"https://ror.org/01vjw4z39","country_code":"CN","type":"education","lineage":["https://openalex.org/I58200834"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shanshan Zhao","raw_affiliation_strings":["Cancer Research Institute, School of Basic Medical Sciences, State Key Laboratory of Organ Failure Research, National Clinical Research Center of Kidney Disease, Key Laboratory of Organ Failure Research (Ministry of Education), Southern Medical University, Guangzhou 510515, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cancer Research Institute, School of Basic Medical Sciences, State Key Laboratory of Organ Failure Research, National Clinical Research Center of Kidney Disease, Key Laboratory of Organ Failure Research (Ministry of Education), Southern Medical University, Guangzhou 510515, China","institution_ids":["https://openalex.org/I58200834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100617566","display_name":"Xiaowei Wu","orcid":"https://orcid.org/0000-0002-9149-0871","observed_orcids":["https://orcid.org/0000-0002-9149-0871"]},"institutions":[{"id":"https://openalex.org/I58200834","display_name":"Southern Medical University","ror":"https://ror.org/01vjw4z39","country_code":"CN","type":"education","lineage":["https://openalex.org/I58200834"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaowei Wu","raw_affiliation_strings":["BSL-3 Laboratory (Guangdong), Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"BSL-3 Laboratory (Guangdong), Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou, China","institution_ids":["https://openalex.org/I58200834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050276158","display_name":"Zhihong Tan","orcid":"https://orcid.org/0000-0003-0583-8489","observed_orcids":["https://orcid.org/0000-0003-0583-8489"]},"institutions":[{"id":"https://openalex.org/I58200834","display_name":"Southern Medical University","ror":"https://ror.org/01vjw4z39","country_code":"CN","type":"education","lineage":["https://openalex.org/I58200834"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhihong Tan","raw_affiliation_strings":["Cancer Research Institute, School of Basic Medical Sciences, State Key Laboratory of Organ Failure Research, National Clinical Research Center of Kidney Disease, Key Laboratory of Organ Failure Research (Ministry of Education), Southern Medical University, Guangzhou 510515, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cancer Research Institute, School of Basic Medical Sciences, State Key Laboratory of Organ Failure Research, National Clinical Research Center of Kidney Disease, Key Laboratory of Organ Failure Research (Ministry of Education), Southern Medical University, Guangzhou 510515, China","institution_ids":["https://openalex.org/I58200834"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Yi Ren","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I159948400","display_name":"Jinan University","ror":"https://ror.org/02xe5ns62","country_code":"CN","type":"education","lineage":["https://openalex.org/I159948400"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yi Ren","raw_affiliation_strings":["Key Laboratory of Ministry of Education for Viral Pathogenesis &amp; Infection Prevention and Control, Institute of Medical Microbiology, Jinan University, Guangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Laboratory of Ministry of Education for Viral Pathogenesis &amp; Infection Prevention and Control, Institute of Medical Microbiology, Jinan University, Guangzhou, China","institution_ids":["https://openalex.org/I159948400"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100317808","display_name":"Lian Li","orcid":"https://orcid.org/0000-0003-4025-805X","observed_orcids":["https://orcid.org/0000-0003-4025-805X"]},"institutions":[{"id":"https://openalex.org/I58200834","display_name":"Southern Medical University","ror":"https://ror.org/01vjw4z39","country_code":"CN","type":"education","lineage":["https://openalex.org/I58200834"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lian Li","raw_affiliation_strings":["Cancer Research Institute, School of Basic Medical Sciences, State Key Laboratory of Organ Failure Research, National Clinical Research Center of Kidney Disease, Key Laboratory of Organ Failure Research (Ministry of Education), Southern Medical University, Guangzhou 510515, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cancer Research Institute, School of Basic Medical Sciences, State Key Laboratory of Organ Failure Research, National Clinical Research Center of Kidney Disease, Key Laboratory of Organ Failure Research (Ministry of Education), Southern Medical University, Guangzhou 510515, China","institution_ids":["https://openalex.org/I58200834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030652001","display_name":"Junxian Ou","orcid":"https://orcid.org/0000-0002-9058-3697","observed_orcids":["https://orcid.org/0000-0002-9058-3697"]},"institutions":[{"id":"https://openalex.org/I159948400","display_name":"Jinan University","ror":"https://ror.org/02xe5ns62","country_code":"CN","type":"education","lineage":["https://openalex.org/I159948400"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Junxian Ou","raw_affiliation_strings":["Key Laboratory of Ministry of Education for Viral Pathogenesis &amp; Infection Prevention and Control, Institute of Medical Microbiology, Jinan University, Guangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Laboratory of Ministry of Education for Viral Pathogenesis &amp; Infection Prevention and Control, Institute of Medical Microbiology, Jinan University, Guangzhou, China","institution_ids":["https://openalex.org/I159948400"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000238307","display_name":"Ying Lin","orcid":"https://orcid.org/0000-0002-3876-5653","observed_orcids":["https://orcid.org/0000-0002-3876-5653"]},"institutions":[{"id":"https://openalex.org/I58200834","display_name":"Southern Medical University","ror":"https://ror.org/01vjw4z39","country_code":"CN","type":"education","lineage":["https://openalex.org/I58200834"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ying Lin","raw_affiliation_strings":["Cancer Research Institute, School of Basic Medical Sciences, State Key Laboratory of Organ Failure Research, National Clinical Research Center of Kidney Disease, Key Laboratory of Organ Failure Research (Ministry of Education), Southern Medical University, Guangzhou 510515, China","Experimental Education/Administration Center, School of Basic Medical Science, Southern Medical University, Guangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cancer Research Institute, School of Basic Medical Sciences, State Key Laboratory of Organ Failure Research, National Clinical Research Center of Kidney Disease, Key Laboratory of Organ Failure Research (Ministry of Education), Southern Medical University, Guangzhou 510515, China","institution_ids":["https://openalex.org/I58200834"]},{"raw_affiliation_string":"Experimental Education/Administration Center, School of Basic Medical Science, Southern Medical University, Guangzhou, China","institution_ids":["https://openalex.org/I58200834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046552608","display_name":"Hongbin Song","orcid":"https://orcid.org/0000-0002-2781-3031","observed_orcids":["https://orcid.org/0000-0002-2781-3031"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hongbin Song","raw_affiliation_strings":["Chinese PLA Center for Disease Control and Prevention, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chinese PLA Center for Disease Control and Prevention, Beijing, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079563757","display_name":"Liqiang Feng","orcid":"https://orcid.org/0000-0001-6811-2074","observed_orcids":["https://orcid.org/0000-0001-6811-2074"]},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I2802148028","display_name":"Guangzhou Institutes of Biomedicine and Health","ror":"https://ror.org/02c31t502","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I2802148028"]},{"id":"https://openalex.org/I4210154954","display_name":"State Key Laboratory of Respiratory Disease","ror":"https://ror.org/04hja5e04","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210154954"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Liqiang Feng","raw_affiliation_strings":["State Key Laboratory of Respiratory Disease, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Respiratory Disease, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I2802148028","https://openalex.org/I4210154954"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076901800","display_name":"Donald Seto","orcid":"https://orcid.org/0000-0002-0379-0330","observed_orcids":["https://orcid.org/0000-0002-0379-0330"]},"institutions":[{"id":"https://openalex.org/I162714631","display_name":"George Mason University","ror":"https://ror.org/02jqj7156","country_code":"US","type":"education","lineage":["https://openalex.org/I162714631"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Donald Seto","raw_affiliation_strings":["Bioinformatics and Computational Biology Program, School of Systems Biology, George Mason University, Manassas, Virginia, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bioinformatics and Computational Biology Program, School of Systems Biology, George Mason University, Manassas, Virginia, USA","institution_ids":["https://openalex.org/I162714631"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044249476","display_name":"Jianguo Wu","orcid":"https://orcid.org/0000-0002-8326-2895","observed_orcids":["https://orcid.org/0000-0002-8326-2895","https://orcid.org/0009-0000-6668-3068"]},"institutions":[{"id":"https://openalex.org/I159948400","display_name":"Jinan University","ror":"https://ror.org/02xe5ns62","country_code":"CN","type":"education","lineage":["https://openalex.org/I159948400"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jianguo Wu","raw_affiliation_strings":["Key Laboratory of Ministry of Education for Viral Pathogenesis &amp; Infection Prevention and Control, Institute of Medical Microbiology, Jinan University, Guangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Laboratory of Ministry of Education for Viral Pathogenesis &amp; Infection Prevention and Control, Institute of Medical Microbiology, Jinan University, Guangzhou, China","institution_ids":["https://openalex.org/I159948400"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100609949","display_name":"Qiwei Zhang","orcid":"https://orcid.org/0000-0002-2770-111X","observed_orcids":["https://orcid.org/0000-0002-2770-111X","https://orcid.org/0000-0001-5952-080X","https://orcid.org/0000-0003-0134-1985"]},"institutions":[{"id":"https://openalex.org/I159948400","display_name":"Jinan University","ror":"https://ror.org/02xe5ns62","country_code":"CN","type":"education","lineage":["https://openalex.org/I159948400"]},{"id":"https://openalex.org/I58200834","display_name":"Southern Medical University","ror":"https://ror.org/01vjw4z39","country_code":"CN","type":"education","lineage":["https://openalex.org/I58200834"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Qiwei Zhang","raw_affiliation_strings":["BSL-3 Laboratory (Guangdong), Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou, China","Key Laboratory of Ministry of Education for Viral Pathogenesis &amp; Infection Prevention and Control, Institute of Medical Microbiology, Jinan University, Guangzhou, China"],"raw_orcid":"https://orcid.org/0000-0002-2770-111X","affiliations":[{"raw_affiliation_string":"BSL-3 Laboratory (Guangdong), Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou, China","institution_ids":["https://openalex.org/I58200834"]},{"raw_affiliation_string":"Key Laboratory of Ministry of Education for Viral Pathogenesis &amp; Infection Prevention and Control, Institute of Medical Microbiology, Jinan University, Guangzhou, China","institution_ids":["https://openalex.org/I159948400"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5089269112","display_name":"Zhili Rong","orcid":"https://orcid.org/0000-0002-1699-7074","observed_orcids":["https://orcid.org/0000-0002-1699-7074"]},"institutions":[{"id":"https://openalex.org/I58200834","display_name":"Southern Medical University","ror":"https://ror.org/01vjw4z39","country_code":"CN","type":"education","lineage":["https://openalex.org/I58200834"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Zhili Rong","raw_affiliation_strings":["Cancer Research Institute, School of Basic Medical Sciences, State Key Laboratory of Organ Failure Research, National Clinical Research Center of Kidney Disease, Key Laboratory of Organ Failure Research (Ministry of Education), Southern Medical University, Guangzhou 510515, China","Dermatology Hospital, Southern Medical University, Guangzhou, China","Experimental Education/Administration Center, School of Basic Medical Science, Southern Medical University, Guangzhou, China"],"raw_orcid":"https://orcid.org/0000-0002-1699-7074","affiliations":[{"raw_affiliation_string":"Cancer Research Institute, School of Basic Medical Sciences, State Key Laboratory of Organ Failure Research, National Clinical Research Center of Kidney Disease, Key Laboratory of Organ Failure Research (Ministry of Education), Southern Medical University, Guangzhou 510515, China","institution_ids":["https://openalex.org/I58200834"]},{"raw_affiliation_string":"Dermatology Hospital, Southern Medical University, Guangzhou, China","institution_ids":["https://openalex.org/I58200834"]},{"raw_affiliation_string":"Experimental Education/Administration Center, School of Basic Medical Science, Southern Medical University, Guangzhou, China","institution_ids":["https://openalex.org/I58200834"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5089269112","https://openalex.org/A5100609949"],"corresponding_institution_ids":["https://openalex.org/I159948400","https://openalex.org/I58200834"],"apc_list":null,"apc_paid":null,"fwci":4.451,"has_fulltext":true,"cited_by_count":28,"citation_normalized_percentile":{"value":0.96201757,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":93,"max":99},"biblio":{"volume":"97","issue":"5","first_page":"e0020923","last_page":"e0020923"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10613","display_name":"Virus-based gene therapy research","score":0.5737000107765198,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10613","display_name":"Virus-based gene therapy research","score":0.5737000107765198,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11243","display_name":"Respiratory viral infections research","score":0.29319998621940613,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10118","display_name":"SARS-CoV-2 and COVID-19 Research","score":0.02539999969303608,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/human-adenovirus-type-3","display_name":"human adenovirus type 3","score":0.8640000224113464},{"id":"https://openalex.org/keywords/lung-organoids","display_name":"lung organoids","score":0.8029999732971191},{"id":"https://openalex.org/keywords/human-embryonic-stem-cells","display_name":"human embryonic stem cells","score":0.9049999713897705},{"id":"https://openalex.org/keywords/adenovirus-infection","display_name":"adenovirus infection","score":0.6159999966621399},{"id":"https://openalex.org/keywords/viral-replication","display_name":"viral replication","score":0.7720000147819519},{"id":"https://openalex.org/keywords/antiviral-drug-evaluation","display_name":"antiviral drug evaluation","score":0.7950000166893005},{"id":"https://openalex.org/keywords/respiratory-tract-infections","display_name":"respiratory infections","score":0.5230000019073486}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.9106253385543823},{"id":"https://openalex.org/C145103041","wikidata":"https://www.wikidata.org/wiki/Q1151519","display_name":"Embryonic stem cell","level":3,"score":0.7262670993804932},{"id":"https://openalex.org/C31695470","wikidata":"https://www.wikidata.org/wiki/Q11293125","display_name":"Organoid","level":2,"score":0.7009801864624023},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.6187694072723389},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.6157261729240417},{"id":"https://openalex.org/C140704245","wikidata":"https://www.wikidata.org/wiki/Q3933202","display_name":"Viral replication","level":3,"score":0.5631665587425232},{"id":"https://openalex.org/C12590798","wikidata":"https://www.wikidata.org/wiki/Q3933199","display_name":"Replication (statistics)","level":2,"score":0.4649812877178192},{"id":"https://openalex.org/C2779756493","wikidata":"https://www.wikidata.org/wiki/Q846227","display_name":"Antiviral drug","level":3,"score":0.41755348443984985},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.33886659145355225},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.33752205967903137},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.32361847162246704},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.27063530683517456},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.1335183084011078},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000066449","descriptor_name":"Human Embryonic Stem Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000258","descriptor_name":"Adenovirus Infections, Human","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D000258","descriptor_name":"Adenovirus Infections, Human","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":true},{"descriptor_ui":"D000260","descriptor_name":"Adenoviruses, Human","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":true},{"descriptor_ui":"D000260","descriptor_name":"Adenoviruses, Human","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000998","descriptor_name":"Antiviral Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008168","descriptor_name":"Lung","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D009940","descriptor_name":"Organoids","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011014","descriptor_name":"Pneumonia","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013045","descriptor_name":"Species Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1128/jvi.00209-23","doi":"https://doi.org/10.1128/jvi.00209-23","is_oa":true,"landing_page_url":"https://doi.org/10.1128/jvi.00209-23","pdf_url":"https://journals.asm.org/doi/pdf/10.1128/jvi.00209-23?download=true","source":{"id":"https://openalex.org/S96615428","display_name":"Journal of Virology","issn_l":"0022-538X","issn":["0022-538X","1070-6321","1098-5514"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Virology","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:10231139","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10231139","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10231139/pdf/jvi.00209-23.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Virol","raw_type":"Text"},{"id":"pmid:37120831","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37120831","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of virology","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1128/jvi.00209-23","doi":"https://doi.org/10.1128/jvi.00209-23","is_oa":true,"landing_page_url":"https://doi.org/10.1128/jvi.00209-23","pdf_url":"https://journals.asm.org/doi/pdf/10.1128/jvi.00209-23?download=true","source":{"id":"https://openalex.org/S96615428","display_name":"Journal of Virology","issn_l":"0022-538X","issn":["0022-538X","1070-6321","1098-5514"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Virology","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9763000011444092,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1022531979","display_name":"\u6f5c\u5728\u4e3b\u8f6c\u5f55\u56e0\u5b50Cebpa\u8c03\u8282II\u578b\u80ba\u6ce1\u7ec6\u80de\u7684\u53d1\u80b2\u3001\u7a33\u6001\u53ca\u518d\u751f\u7684\u5206\u5b50\u673a\u5236\u7814\u7a76","funder_award_id":"82070002","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G1419713913","display_name":null,"funder_award_id":"2018YFE0204503","funder_id":"https://openalex.org/F4320335777","funder_display_name":"National Key Research and Development Program of China"},{"id":"https://openalex.org/G1430642322","display_name":null,"funder_award_id":"32170139","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G3072428880","display_name":null,"funder_award_id":"SRPG22-006","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G3304656609","display_name":null,"funder_award_id":"2022A1515011091","funder_id":"https://openalex.org/F4320337111","funder_display_name":"Basic and Applied Basic Research Foundation of Guangdong Province"},{"id":"https://openalex.org/G3348307466","display_name":null,"funder_award_id":"2021A1515010788","funder_id":"https://openalex.org/F4320324202","funder_display_name":"Guangdong Science and Technology Department"},{"id":"https://openalex.org/G3523954668","display_name":null,"funder_award_id":"2022YFA0806300","funder_id":"https://openalex.org/F4320335777","funder_display_name":"National Key Research and Development Program of China"},{"id":"https://openalex.org/G376603064","display_name":null,"funder_award_id":"2022A1515011190","funder_id":"https://openalex.org/F4320337111","funder_display_name":"Basic and Applied Basic Research Foundation of Guangdong Province"},{"id":"https://openalex.org/G3948786894","display_name":null,"funder_award_id":"92269103","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G4638162253","display_name":null,"funder_award_id":"21622101","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G5956465385","display_name":null,"funder_award_id":"21622101","funder_id":"https://openalex.org/F4320335787","funder_display_name":"Fundamental Research Funds for the Central Universities"},{"id":"https://openalex.org/G6839237722","display_name":null,"funder_award_id":"82072329","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G6857372607","display_name":null,"funder_award_id":"2021B1515140031","funder_id":"https://openalex.org/F4320337111","funder_display_name":"Basic and Applied Basic Research Foundation of Guangdong Province"},{"id":"https://openalex.org/G7842849146","display_name":null,"funder_award_id":"2023A1515012269","funder_id":"https://openalex.org/F4320337111","funder_display_name":"Basic and Applied Basic Research Foundation of Guangdong Province"},{"id":"https://openalex.org/G8096150218","display_name":null,"funder_award_id":"2021A1515010788","funder_id":"https://openalex.org/F4320337111","funder_display_name":"Basic and Applied Basic Research Foundation of Guangdong Province"},{"id":"https://openalex.org/G8695446210","display_name":null,"funder_award_id":"2022A1515011190","funder_id":"https://openalex.org/F4320324202","funder_display_name":"Guangdong Science and Technology Department"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320324202","display_name":"Guangdong Science and Technology Department","ror":"https://ror.org/00tjzgn92"},{"id":"https://openalex.org/F4320335777","display_name":"National Key Research and Development Program of China","ror":null},{"id":"https://openalex.org/F4320335787","display_name":"Fundamental Research Funds for the Central Universities","ror":null},{"id":"https://openalex.org/F4320337111","display_name":"Basic and Applied Basic Research Foundation of Guangdong Province","ror":null}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4367550232.pdf","grobid_xml":"https://content.openalex.org/works/W4367550232.grobid-xml"},"referenced_works_count":66,"referenced_works":["https://openalex.org/W75219164","https://openalex.org/W1590398299","https://openalex.org/W1633543929","https://openalex.org/W1834331175","https://openalex.org/W1840938093","https://openalex.org/W1888026451","https://openalex.org/W1971765707","https://openalex.org/W1976868395","https://openalex.org/W1998385063","https://openalex.org/W2025344688","https://openalex.org/W2028042551","https://openalex.org/W2042943782","https://openalex.org/W2051164613","https://openalex.org/W2071755319","https://openalex.org/W2080546358","https://openalex.org/W2080730740","https://openalex.org/W2096864778","https://openalex.org/W2099060352","https://openalex.org/W2110856952","https://openalex.org/W2131881926","https://openalex.org/W2168652503","https://openalex.org/W2282335838","https://openalex.org/W2331628193","https://openalex.org/W2441337908","https://openalex.org/W2487775023","https://openalex.org/W2529774907","https://openalex.org/W2547445568","https://openalex.org/W2553841146","https://openalex.org/W2556732574","https://openalex.org/W2609587333","https://openalex.org/W2613408861","https://openalex.org/W2623865818","https://openalex.org/W2773981699","https://openalex.org/W2788735115","https://openalex.org/W2794409088","https://openalex.org/W2794579455","https://openalex.org/W2794800900","https://openalex.org/W2799444748","https://openalex.org/W2799736418","https://openalex.org/W2803870471","https://openalex.org/W2804078183","https://openalex.org/W2888948928","https://openalex.org/W2905061555","https://openalex.org/W2911899687","https://openalex.org/W2913658477","https://openalex.org/W2914134723","https://openalex.org/W2914930796","https://openalex.org/W2944420557","https://openalex.org/W2947470486","https://openalex.org/W2963919039","https://openalex.org/W3001126043","https://openalex.org/W3029719263","https://openalex.org/W3037208121","https://openalex.org/W3044276949","https://openalex.org/W3080539014","https://openalex.org/W3093654299","https://openalex.org/W3108853108","https://openalex.org/W3112109511","https://openalex.org/W3123177379","https://openalex.org/W3127536399","https://openalex.org/W3155589735","https://openalex.org/W3157179090","https://openalex.org/W3175959067","https://openalex.org/W3182593619","https://openalex.org/W3194441010","https://openalex.org/W4280528593"],"related_works":["https://openalex.org/W3003543301","https://openalex.org/W2914930796","https://openalex.org/W2169062436","https://openalex.org/W898847178","https://openalex.org/W4407147842","https://openalex.org/W6985000045","https://openalex.org/W4211218603","https://openalex.org/W2131881926","https://openalex.org/W4205460033","https://openalex.org/W7214113196"],"abstract_inverted_index":{"Human":[0],"adenovirus":[1],"(HAdV)":[2],"infections":[3],"are":[4],"a":[5],"major":[6],"threat":[7],"worldwide.":[8],"HAdV-3":[9],"is":[10],"one":[11],"of":[12],"the":[13],"most":[14],"predominant":[15],"respiratory":[16],"pathogen":[17],"types":[18],"found":[19],"in":[20],"children.":[21]},"counts_by_year":[{"year":2026,"cited_by_count":6},{"year":2025,"cited_by_count":9},{"year":2024,"cited_by_count":11},{"year":2023,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2023-05-01T00:00:00"}
