{"id":"https://openalex.org/W4367394971","doi":"https://doi.org/10.1093/ced/llad161","title":"Topical steroid withdrawal: an emerging clinical problem","display_name":"Topical steroid withdrawal: an emerging clinical problem","publication_year":2023,"publication_date":"2023-04-29","ids":{"openalex":"https://openalex.org/W4367394971","doi":"https://doi.org/10.1093/ced/llad161","pmid":"https://pubmed.ncbi.nlm.nih.gov/37119282"},"language":"en","primary_location":{"id":"doi:10.1093/ced/llad161","doi":"https://doi.org/10.1093/ced/llad161","is_oa":false,"landing_page_url":"https://doi.org/10.1093/ced/llad161","pdf_url":null,"source":{"id":"https://openalex.org/S80252431","display_name":"Clinical and Experimental Dermatology","issn_l":"0307-6938","issn":["0307-6938","1365-2230"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical and Experimental Dermatology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5027742642","display_name":"Tenzin Sung-rab Brookes","orcid":"https://orcid.org/0000-0003-2509-4528","observed_orcids":["https://orcid.org/0000-0003-2509-4528"]},"institutions":[{"id":"https://openalex.org/I2799869770","display_name":"Chelsea and Westminster Hospital NHS Foundation Trust","ror":"https://ror.org/02gd18467","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2799869770"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Tenzin Sung-rab Brookes","raw_affiliation_strings":["Chelsea & Westminster Hospital NHS Foundation Trust , London , UK"],"raw_orcid":"https://orcid.org/0000-0003-2509-4528","affiliations":[{"raw_affiliation_string":"Chelsea & Westminster Hospital NHS Foundation Trust , London , UK","institution_ids":["https://openalex.org/I2799869770"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5114310145","display_name":"Richard Barlow","orcid":"https://orcid.org/0000-0001-8667-3529","observed_orcids":["https://orcid.org/0000-0001-8667-3529"]},"institutions":[{"id":"https://openalex.org/I2799630439","display_name":"Sandwell & West Birmingham Hospitals NHS Trust","ror":"https://ror.org/05mzf3276","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2799630439"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Richard Barlow","raw_affiliation_strings":["Sandwell and West Birmingham NHS Trust , West Midlands , UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sandwell and West Birmingham NHS Trust , West Midlands , UK","institution_ids":["https://openalex.org/I2799630439"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022990322","display_name":"Padma Mohandas","orcid":"https://orcid.org/0000-0003-0428-8374","observed_orcids":["https://orcid.org/0000-0003-0428-8374"]},"institutions":[{"id":"https://openalex.org/I225661044","display_name":"Barts Health NHS Trust","ror":"https://ror.org/00b31g692","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I225661044"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Padma Mohandas","raw_affiliation_strings":["Barts Health NHS Trust , London , UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Barts Health NHS Trust , London , UK","institution_ids":["https://openalex.org/I225661044"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5072258821","display_name":"Anthony Bewley","orcid":"https://orcid.org/0000-0003-1195-0290","observed_orcids":["https://orcid.org/0000-0003-1195-0290"]},"institutions":[{"id":"https://openalex.org/I225661044","display_name":"Barts Health NHS Trust","ror":"https://ror.org/00b31g692","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I225661044"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Anthony Bewley","raw_affiliation_strings":["Barts Health NHS Trust , London , UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Barts Health NHS Trust , London , UK","institution_ids":["https://openalex.org/I225661044"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5027742642"],"corresponding_institution_ids":["https://openalex.org/I2799869770"],"apc_list":{"value":2329,"currency":"GBP","value_usd":2897},"apc_paid":null,"fwci":9.3259,"has_fulltext":false,"cited_by_count":38,"citation_normalized_percentile":{"value":0.98651029,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":87,"max":100},"biblio":{"volume":"48","issue":"9","first_page":"1007","last_page":"1011"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10837","display_name":"Dermatology and Skin Diseases","score":0.9848999977111816,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10837","display_name":"Dermatology and Skin Diseases","score":0.9848999977111816,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11033","display_name":"Contact Dermatitis and Allergies","score":0.011300000362098217,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11334","display_name":"Psychosomatic Disorders and Their Treatments","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/topical-steroid-withdrawal","display_name":"topical steroid withdrawal","score":0.9599999785423279},{"id":"https://openalex.org/keywords/topical-corticosteroids","display_name":"topical corticosteroids","score":0.8289999961853027},{"id":"https://openalex.org/keywords/atopic-dermatitis","display_name":"atopic dermatitis","score":0.9419999718666077},{"id":"https://openalex.org/keywords/erythema","display_name":"erythema","score":0.6420000195503235},{"id":"https://openalex.org/keywords/psychodermatology","display_name":"psychodermatology","score":0.9229999780654907},{"id":"https://openalex.org/keywords/anxiety-and-depression","display_name":"anxiety and depression","score":0.828000009059906},{"id":"https://openalex.org/keywords/suicidal-ideation","display_name":"suicidal ideation","score":0.8100000023841858},{"id":"https://openalex.org/keywords/shared-decision-making","display_name":"shared decision-making","score":0.9020000100135803}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8278077840805054},{"id":"https://openalex.org/C2778715236","wikidata":"https://www.wikidata.org/wiki/Q55622662","display_name":"Discontinuation","level":2,"score":0.6649494171142578},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.5162713527679443},{"id":"https://openalex.org/C2776867660","wikidata":"https://www.wikidata.org/wiki/Q1814941","display_name":"Depression (economics)","level":2,"score":0.4898812174797058},{"id":"https://openalex.org/C558461103","wikidata":"https://www.wikidata.org/wiki/Q154430","display_name":"Anxiety","level":2,"score":0.4410303831100464},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.4288181960582733},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.35929104685783386},{"id":"https://openalex.org/C16005928","wikidata":"https://www.wikidata.org/wiki/Q171171","display_name":"Dermatology","level":1,"score":0.34548041224479675},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C139719470","wikidata":"https://www.wikidata.org/wiki/Q39680","display_name":"Macroeconomics","level":1,"score":0.0},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003876","descriptor_name":"Dermatitis, Atopic","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":true},{"descriptor_ui":"D003876","descriptor_name":"Dermatitis, Atopic","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D003879","descriptor_name":"Dermatologic Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D004890","descriptor_name":"Erythema","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":false},{"descriptor_ui":"D004890","descriptor_name":"Erythema","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011537","descriptor_name":"Pruritus","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D013256","descriptor_name":"Steroids","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1093/ced/llad161","doi":"https://doi.org/10.1093/ced/llad161","is_oa":false,"landing_page_url":"https://doi.org/10.1093/ced/llad161","pdf_url":null,"source":{"id":"https://openalex.org/S80252431","display_name":"Clinical and Experimental Dermatology","issn_l":"0307-6938","issn":["0307-6938","1365-2230"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical and Experimental Dermatology","raw_type":"journal-article"},{"id":"pmid:37119282","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37119282","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical and experimental dermatology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":12,"referenced_works":["https://openalex.org/W1973233731","https://openalex.org/W2081818133","https://openalex.org/W2755054086","https://openalex.org/W2808929939","https://openalex.org/W2895660476","https://openalex.org/W2913463065","https://openalex.org/W3024469835","https://openalex.org/W3196097628","https://openalex.org/W3196862253","https://openalex.org/W4220775283","https://openalex.org/W4239555317","https://openalex.org/W4285390130"],"related_works":["https://openalex.org/W4391558946","https://openalex.org/W4382025400","https://openalex.org/W7124530559","https://openalex.org/W4413109105","https://openalex.org/W4416958197","https://openalex.org/W7137832946","https://openalex.org/W4410945645","https://openalex.org/W4417458417","https://openalex.org/W7118159240","https://openalex.org/W7166127491"],"abstract_inverted_index":{"BACKGROUND:":[0],"Topical":[1],"steroid":[2],"withdrawal":[3],"(TSW)":[4],"is":[5,32],"a":[6,142],"newly":[7],"described":[8],"disease":[9],"characterized":[10],"by":[11,159,196],"erythema":[12],"and":[13,58,83,105,137,147,216,228],"burning":[14],"following":[15],"discontinuation":[16],"of":[17,20,37,62,72,98,145,165,179,187,213,226],"prolonged":[18],"use":[19],"mid-":[21],"to":[22,44,89,203,223],"high-potency":[23],"topical":[24,45],"corticosteroids.":[25],"No":[26],"consensus":[27],"diagnostic":[28],"criterion":[29],"exists.":[30],"TSW":[31,51,99,227],"frequently":[33,122],"interpreted":[34],"as":[35],"flaring":[36],"the":[38,60,162,177,211],"underlying":[39],"disorder":[40],"or":[41],"contact":[42],"allergy":[43],"treatment.":[46],"OBJECTIVES:":[47],"To":[48],"better":[49],"characterize":[50],"symptomatology,":[52],"detail":[53],"our":[54,77],"experience":[55],"with":[56,93,149,170,183,231],"management":[57,189],"assess":[59],"proportion":[61],"patients":[63,91,151,193],"who":[64],"pursue":[65],"nonconventional":[66],"management.":[67],"METHODS:":[68],"A":[69],"retrospective":[70],"review":[71],"case":[73],"notes":[74],"collected":[75],"from":[76,206],"multidisciplinary":[78],"service":[79],"between":[80],"January":[81],"2019":[82],"June":[84],"2021":[85],"was":[86,141],"carried":[87],"out":[88],"identify":[90],"presenting":[92],"TSW.":[94],"RESULTS:":[95],"Nineteen":[96],"cases":[97],"were":[100,111,125,157,174],"identified,":[101],"15":[102],"in":[103,107,176],"females":[104],"4":[106],"males.":[108],"The":[109,120],"majority":[110],"<":[112],"35":[113],"years":[114],"old.":[115],"Eighteen":[116],"had":[117],"atopic":[118],"dermatitis.":[119],"most":[121],"reported":[123],"features":[124],"redness,":[126],"skin":[127,131,134],"pain":[128],"(typically":[129],"'burning'),":[130],"sensitivity,":[132],"excessive":[133],"flaking,":[135],"insomnia":[136],"severe":[138],"itching.":[139],"There":[140],"high":[143],"burden":[144,212],"anxiety":[146],"depression,":[148],"three":[150],"expressing":[152],"suicidal":[153],"thoughts.":[154],"Nonconventional":[155],"treatments":[156],"pursued":[158],"approximately":[160],"half":[161],"cohort,":[163],"some":[164],"whom":[166],"sought":[167],"private":[168],"consultation":[169],"international":[171],"dermatologists.":[172],"Improvements":[173],"noted":[175],"context":[178],"open":[180],"psychodermatology":[181],"consultations":[182],"an":[184],"earlier":[185],"introduction":[186],"conventional":[188],"options.":[190],"CONCLUSIONS:":[191],"Many":[192],"report":[194],"dismissal":[195],"dermatology":[197],"healthcare":[198,220],"professionals,":[199],"often":[200],"driving":[201],"them":[202],"seek":[204],"help":[205],"unregulated":[207],"online":[208],"sources,":[209],"heightening":[210],"mental,":[214],"social":[215],"physical":[217],"morbidity.":[218],"Dermatology":[219],"professionals":[221],"need":[222],"be":[224],"aware":[225],"offer":[229],"support":[230],"shared":[232],"decision-making":[233],"when":[234],"considering":[235],"treatments.":[236]},"counts_by_year":[{"year":2026,"cited_by_count":8},{"year":2025,"cited_by_count":19},{"year":2024,"cited_by_count":10},{"year":2021,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2023-04-30T00:00:00"}