{"id":"https://openalex.org/W4367359372","doi":"https://doi.org/10.1615/critrevtherdrugcarriersyst.2023044994","title":"Copper Nanoclusters as Novel Podium for Cancer Detection, Imaging, and Therapy Applications","display_name":"Copper Nanoclusters as Novel Podium for Cancer Detection, Imaging, and Therapy Applications","publication_year":2023,"publication_date":"2023-04-28","ids":{"openalex":"https://openalex.org/W4367359372","doi":"https://doi.org/10.1615/critrevtherdrugcarriersyst.2023044994","pmid":"https://pubmed.ncbi.nlm.nih.gov/37938190"},"language":"en","primary_location":{"id":"doi:10.1615/critrevtherdrugcarriersyst.2023044994","doi":"https://doi.org/10.1615/critrevtherdrugcarriersyst.2023044994","is_oa":false,"landing_page_url":"https://doi.org/10.1615/critrevtherdrugcarriersyst.2023044994","pdf_url":null,"source":{"id":"https://openalex.org/S22829174","display_name":"Critical Reviews in Therapeutic Drug Carrier Systems","issn_l":"0743-4863","issn":["0743-4863","2162-660X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315730","host_organization_name":"Begell House","host_organization_lineage":["https://openalex.org/P4310315730"],"host_organization_lineage_names":["Begell House"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Critical Reviews\u2122 in Therapeutic Drug Carrier Systems","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Ranjita Misra","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I106826634","display_name":"Jain University","ror":"https://ror.org/01cnqpt53","country_code":"IN","type":"education","lineage":["https://openalex.org/I106826634"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"Ranjita Misra","raw_affiliation_strings":["Department of Biotechnology, School of Sciences, Jain University, Bangalore, Karnataka, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biotechnology, School of Sciences, Jain University, Bangalore, Karnataka, India","institution_ids":["https://openalex.org/I106826634"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026776388","display_name":"A. Sivaranjani","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405253052","display_name":"Advanced Institute for Wildlife Conservation","ror":"https://ror.org/008gcn350","country_code":"IN","type":"facility","lineage":["https://openalex.org/I4405253052"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"A. Sivaranjani","raw_affiliation_strings":["Advanced Institute for Wildlife Conservation, Chennai, Tamil Nadu, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Advanced Institute for Wildlife Conservation, Chennai, Tamil Nadu, India","institution_ids":["https://openalex.org/I4405253052"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058730974","display_name":"Suraiya Saleem","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I24676775","display_name":"Indian Institute of Technology Madras","ror":"https://ror.org/03v0r5n49","country_code":"IN","type":"education","lineage":["https://openalex.org/I24676775"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Suraiya Saleem","raw_affiliation_strings":["Department of Biotechnology, Indian Institute of Technology, Madras, Chennai 600036, Tamil Nadu, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biotechnology, Indian Institute of Technology, Madras, Chennai 600036, Tamil Nadu, India","institution_ids":["https://openalex.org/I24676775"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5026219057","display_name":"Bignya Rani Dash","orcid":"https://orcid.org/0000-0002-6062-9789","observed_orcids":["https://orcid.org/0000-0002-6062-9789"]},"institutions":[{"id":"https://openalex.org/I24676775","display_name":"Indian Institute of Technology Madras","ror":"https://ror.org/03v0r5n49","country_code":"IN","type":"education","lineage":["https://openalex.org/I24676775"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Bignya Rani Dash","raw_affiliation_strings":["Department of Chemistry, Indian Institute of Technology, Madras, Chennai 600036, Tamil Nadu, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Indian Institute of Technology, Madras, Chennai 600036, Tamil Nadu, India","institution_ids":["https://openalex.org/I24676775"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I106826634"],"apc_list":null,"apc_paid":null,"fwci":0.0772,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":{"value":0.04910714,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"41","issue":"2","first_page":"51","last_page":"80"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12149","display_name":"Nanocluster Synthesis and Applications","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T12149","display_name":"Nanocluster Synthesis and Applications","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10321","display_name":"Quantum Dots Synthesis And Properties","score":0.0010999999940395355,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11240","display_name":"Luminescence and Fluorescent Materials","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/copper-nanoclusters","display_name":"copper nanoclusters","score":1.0},{"id":"https://openalex.org/keywords/theranostics","display_name":"theranostics","score":0.7609999775886536},{"id":"https://openalex.org/keywords/cancer-detection","display_name":"cancer detection","score":0.8610000014305115},{"id":"https://openalex.org/keywords/tumor-imaging","display_name":"tumor imaging","score":0.8240000009536743},{"id":"https://openalex.org/keywords/cancer-therapy","display_name":"cancer therapy","score":0.9330000281333923},{"id":"https://openalex.org/keywords/nanocluster-synthesis","display_name":"nanocluster synthesis","score":0.9150000214576721},{"id":"https://openalex.org/keywords/surface-modification","display_name":"surface modification","score":0.9800000190734863},{"id":"https://openalex.org/keywords/luminescence-regulation","display_name":"luminescence regulation","score":0.6320000290870667}],"concepts":[{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.7720867395401001},{"id":"https://openalex.org/C2778402822","wikidata":"https://www.wikidata.org/wiki/Q22302226","display_name":"Nanoclusters","level":2,"score":0.5567831993103027},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.41502317786216736},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.36150872707366943}],"mesh":[{"descriptor_ui":"D000554","descriptor_name":"Ambulatory Care Facilities","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003300","descriptor_name":"Copper","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003952","descriptor_name":"Diagnostic Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009353","descriptor_name":"Zinostatin","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D014131","descriptor_name":"Trace Elements","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1615/critrevtherdrugcarriersyst.2023044994","doi":"https://doi.org/10.1615/critrevtherdrugcarriersyst.2023044994","is_oa":false,"landing_page_url":"https://doi.org/10.1615/critrevtherdrugcarriersyst.2023044994","pdf_url":null,"source":{"id":"https://openalex.org/S22829174","display_name":"Critical Reviews in Therapeutic Drug Carrier Systems","issn_l":"0743-4863","issn":["0743-4863","2162-660X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315730","host_organization_name":"Begell House","host_organization_lineage":["https://openalex.org/P4310315730"],"host_organization_lineage_names":["Begell House"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Critical Reviews\u2122 in Therapeutic Drug Carrier Systems","raw_type":"journal-article"},{"id":"pmid:37938190","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37938190","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Critical reviews in therapeutic drug carrier systems","raw_type":"Review"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9391000270843506,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":132,"referenced_works":["https://openalex.org/W1491466439","https://openalex.org/W1834998094","https://openalex.org/W1955748210","https://openalex.org/W1966857466","https://openalex.org/W1967165672","https://openalex.org/W1968877074","https://openalex.org/W1971191584","https://openalex.org/W1972461780","https://openalex.org/W1974204042","https://openalex.org/W1975666741","https://openalex.org/W1976734180","https://openalex.org/W1978733293","https://openalex.org/W1988436608","https://openalex.org/W1992612475","https://openalex.org/W1995508516","https://openalex.org/W1999401096","https://openalex.org/W2003212162","https://openalex.org/W2004040475","https://openalex.org/W2015598344","https://openalex.org/W2029325023","https://openalex.org/W2030488176","https://openalex.org/W2030522563","https://openalex.org/W2040933290","https://openalex.org/W2043010740","https://openalex.org/W2043402257","https://openalex.org/W2045435533","https://openalex.org/W2045893033","https://openalex.org/W2051904939","https://openalex.org/W2053080832","https://openalex.org/W2055571564","https://openalex.org/W2059312061","https://openalex.org/W2061590003","https://openalex.org/W2066324249","https://openalex.org/W2068677870","https://openalex.org/W2070003597","https://openalex.org/W2072453414","https://openalex.org/W2075846064","https://openalex.org/W2077519904","https://openalex.org/W2079722732","https://openalex.org/W2089881610","https://openalex.org/W2090800146","https://openalex.org/W2093329874","https://openalex.org/W2093760220","https://openalex.org/W2094627594","https://openalex.org/W2100173894","https://openalex.org/W2102119006","https://openalex.org/W2108090591","https://openalex.org/W2135362692","https://openalex.org/W2135917319","https://openalex.org/W2138091227","https://openalex.org/W2140583024","https://openalex.org/W2148628717","https://openalex.org/W2154274753","https://openalex.org/W2156496648","https://openalex.org/W2158546379","https://openalex.org/W2161032693","https://openalex.org/W2161946327","https://openalex.org/W2169625143","https://openalex.org/W2169633689","https://openalex.org/W2176055767","https://openalex.org/W2271271971","https://openalex.org/W2298480233","https://openalex.org/W2316139568","https://openalex.org/W2318577761","https://openalex.org/W2327517604","https://openalex.org/W2343538534","https://openalex.org/W2396078929","https://openalex.org/W2415528931","https://openalex.org/W2423276331","https://openalex.org/W2516640651","https://openalex.org/W2522786024","https://openalex.org/W2556338331","https://openalex.org/W2557289526","https://openalex.org/W2582730147","https://openalex.org/W2587356623","https://openalex.org/W2589632813","https://openalex.org/W2598621934","https://openalex.org/W2601126877","https://openalex.org/W2606450799","https://openalex.org/W2613645383","https://openalex.org/W2620539488","https://openalex.org/W2748930387","https://openalex.org/W2753179766","https://openalex.org/W2768006516","https://openalex.org/W2774780937","https://openalex.org/W2777003222","https://openalex.org/W2789311359","https://openalex.org/W2794786066","https://openalex.org/W2807410315","https://openalex.org/W2884126108","https://openalex.org/W2899702190","https://openalex.org/W2901748905","https://openalex.org/W2903556724","https://openalex.org/W2907439950","https://openalex.org/W2944013591","https://openalex.org/W2969178261","https://openalex.org/W2981823300","https://openalex.org/W2990983561","https://openalex.org/W2995156266","https://openalex.org/W3001273987","https://openalex.org/W3003771063","https://openalex.org/W3011048460","https://openalex.org/W3039337614","https://openalex.org/W3040705835","https://openalex.org/W3042647781","https://openalex.org/W3083971058","https://openalex.org/W3084062066","https://openalex.org/W3087198975","https://openalex.org/W3096050902","https://openalex.org/W3102722916","https://openalex.org/W3111035599","https://openalex.org/W3131802816","https://openalex.org/W3143320972","https://openalex.org/W3157953730","https://openalex.org/W3159482184","https://openalex.org/W3160952750","https://openalex.org/W3172754262","https://openalex.org/W3184072950","https://openalex.org/W3187397380","https://openalex.org/W3194316507","https://openalex.org/W4200110282","https://openalex.org/W4205548856","https://openalex.org/W4220867345","https://openalex.org/W4226480458","https://openalex.org/W4229024610","https://openalex.org/W4250860551","https://openalex.org/W4255924897","https://openalex.org/W4288447991","https://openalex.org/W4296037858","https://openalex.org/W4302027597","https://openalex.org/W4309246517","https://openalex.org/W4313419247"],"related_works":["https://openalex.org/W3001273987","https://openalex.org/W4205548856","https://openalex.org/W4377013633","https://openalex.org/W2944013591","https://openalex.org/W4293069798","https://openalex.org/W2997715079","https://openalex.org/W3024435796","https://openalex.org/W3135183420","https://openalex.org/W4281726181","https://openalex.org/W2221369375"],"abstract_inverted_index":{"Nanoclusters":[0],"(NCs)":[1],"are":[2,25,39,59],"meticulously":[3],"small,":[4],"kinetically":[5],"stable,":[6],"crystalline":[7],"materials":[8,44],"which":[9],"hold":[10],"immense":[11],"potential":[12,123,196],"as":[13,42,45,61,197],"multifaceted":[14],"catalysts":[15],"for":[16,102,209],"a":[17,98],"broad":[18],"range":[19,32],"of":[20,33,36,73,119,152,156,175,192],"biomedical":[21],"applications.":[22],"Metal":[23],"NCs":[24,57],"atomically":[26],"precise":[27],"and":[28,81,93,116,150,159,171,178,194,207,225],"exist":[29],"within":[30],"the":[31,66,89,110,113,137,145,165,173,189,205,216,219],"Fermi":[34],"wavelength":[35],"electrons.":[37],"They":[38],"highly":[40,76],"advantageous":[41],"functional":[43],"their":[46,195],"physicochemical":[47],"properties":[48],"can":[49,105,221],"be":[50,106,222],"customized":[51],"to":[52,65,91,169,187,218],"meet":[53],"specific":[54],"requirements.":[55],"Copper":[56],"(CuNCs)":[58],"emerging":[60,198],"an":[62],"efficient":[63],"substitute":[64],"other":[67],"existing":[68,211],"metal":[69],"NCs.":[70],"The":[71,141],"synthesis":[72],"CuNCs":[74,131,153,193,214],"is":[75,97,202],"methodical,":[77],"fast,":[78],"cost":[79],"effective":[80],"does":[82],"not":[83],"involve":[84],"any":[85],"complicated":[86],"manipulation.":[87],"On":[88],"contrary":[90],"gold":[92],"silver":[94],"NCs,":[95],"copper":[96,120],"vital":[99],"trace":[100],"element":[101],"humans":[103],"that":[104,204],"excreted":[107],"easily":[108],"out":[109],"body.":[111],"Further,":[112],"relatively":[114],"inexpensiveness":[115],"easy":[117],"availability":[118],"aids":[121],"in":[122,126,144,154,164,213],"nanotechnological":[124],"applications":[125,191],"large":[127],"quantity.":[128],"As":[129],"such,":[130],"have":[132,161,180],"attracted":[133],"great":[134],"interest":[135],"among":[136],"research":[138],"community":[139],"recently.":[140],"modern":[142],"developments":[143,212],"strategy,":[146],"synthesis,":[147],"surface":[148],"modifications,":[149],"use":[151],"diagnosis":[155],"disease,":[157],"imaging":[158],"treatment":[160],"been":[162,182],"discussed":[163],"present":[166],"review.":[167],"Approaches":[168],"regulate":[170],"augment":[172],"emission":[174],"CuNCs,":[176],"challenges":[177],"drawbacks":[179],"also":[181],"considered.":[183],"This":[184],"review":[185],"brings":[186],"light":[188],"multifarious":[190],"theranostic":[199],"agents.":[200],"It":[201],"anticipated":[203],"visions":[206],"directions":[208],"translating":[210],"from":[215],"laboratory":[217],"clinic":[220],"further":[223],"improved":[224],"enhanced.":[226]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2023-04-30T00:00:00"}