{"id":"https://openalex.org/W4367338928","doi":"https://doi.org/10.4103/idoj.idoj_472_22","title":"Hyper-immunoglobulin E syndrome: Case series of 6 children from India","display_name":"Hyper-immunoglobulin E syndrome: Case series of 6 children from India","publication_year":2023,"publication_date":"2023-01-01","ids":{"openalex":"https://openalex.org/W4367338928","doi":"https://doi.org/10.4103/idoj.idoj_472_22","pmid":"https://pubmed.ncbi.nlm.nih.gov/37266097","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/10231702"},"language":"en","primary_location":{"id":"doi:10.4103/idoj.idoj_472_22","doi":"https://doi.org/10.4103/idoj.idoj_472_22","is_oa":true,"landing_page_url":"https://doi.org/10.4103/idoj.idoj_472_22","pdf_url":null,"source":{"id":"https://openalex.org/S2754097677","display_name":"Indian Dermatology Online Journal","issn_l":"2229-5178","issn":["2229-5178","2249-5673"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","doyens","ki-jl-1","poland-20","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320448","host_organization_name":"Medknow","host_organization_lineage":["https://openalex.org/P4310320448","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Medknow","Wolters Kluwer"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Indian Dermatology Online Journal","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://doi.org/10.4103/idoj.idoj_472_22","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5066442707","display_name":"Sunmeet Sandhu","orcid":"https://orcid.org/0000-0002-9222-4006","observed_orcids":["https://orcid.org/0000-0002-9222-4006"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Sunmeet Sandhu","raw_affiliation_strings":["Department of Dermatology, Sree Mookambika Institute of Medical Sciences, Kulasekharam, Kanyakumari, Tamil Nadu, India","1Consultant Dermatologist, Edappal Hospitals Pvt Limited, Kerala, India; 2Department of Dermatology, Sree Mookambika Institute of Medical Sciences, Kulasekharam, Kanyakumari, Tamil Nadu, India; 3Department of Dermatology, 7 Air Force Hospital, Kanpur, India; 4Department of Dermatology, Base Hospital, Lucknow, Uttar Pradesh, India; This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike Alike 4.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dermatology, Sree Mookambika Institute of Medical Sciences, Kulasekharam, Kanyakumari, Tamil Nadu, India","institution_ids":[]},{"raw_affiliation_string":"1Consultant Dermatologist, Edappal Hospitals Pvt Limited, Kerala, India; 2Department of Dermatology, Sree Mookambika Institute of Medical Sciences, Kulasekharam, Kanyakumari, Tamil Nadu, India; 3Department of Dermatology, 7 Air Force Hospital, Kanpur, India; 4Department of Dermatology, Base Hospital, Lucknow, Uttar Pradesh, India; This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike Alike 4.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064167540","display_name":"Rohit Sanjay Kothari","orcid":"https://orcid.org/0000-0002-9875-2563","observed_orcids":["https://orcid.org/0000-0002-9875-2563"]},"institutions":[{"id":"https://openalex.org/I4210153078","display_name":"Command Hospital Air Force","ror":"https://ror.org/05cx69s52","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I2801959050","https://openalex.org/I4210153078"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Rohit Kothari","raw_affiliation_strings":["Department of Dermatology, Command Hospital Air Force, Bengaluru, Karnataka, India","1Consultant Dermatologist, Edappal Hospitals Pvt Limited, Kerala, India; 2Department of Dermatology, Sree Mookambika Institute of Medical Sciences, Kulasekharam, Kanyakumari, Tamil Nadu, India; 3Department of Dermatology, 7 Air Force Hospital, Kanpur, India; 4Department of Dermatology, Base Hospital, Lucknow, Uttar Pradesh, India; This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike Alike 4.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dermatology, Command Hospital Air Force, Bengaluru, Karnataka, India","institution_ids":["https://openalex.org/I4210153078"]},{"raw_affiliation_string":"1Consultant Dermatologist, Edappal Hospitals Pvt Limited, Kerala, India; 2Department of Dermatology, Sree Mookambika Institute of Medical Sciences, Kulasekharam, Kanyakumari, Tamil Nadu, India; 3Department of Dermatology, 7 Air Force Hospital, Kanpur, India; 4Department of Dermatology, Base Hospital, Lucknow, Uttar Pradesh, India; This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike Alike 4.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112640147","display_name":"Muneer Mohamed","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210153078","display_name":"Command Hospital Air Force","ror":"https://ror.org/05cx69s52","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I2801959050","https://openalex.org/I4210153078"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Muneer Mohamed","raw_affiliation_strings":["Department of Dermatology, Command Hospital Air Force, Bengaluru, Karnataka, India","1Consultant Dermatologist, Edappal Hospitals Pvt Limited, Kerala, India; 2Department of Dermatology, Sree Mookambika Institute of Medical Sciences, Kulasekharam, Kanyakumari, Tamil Nadu, India; 3Department of Dermatology, 7 Air Force Hospital, Kanpur, India; 4Department of Dermatology, Base Hospital, Lucknow, Uttar Pradesh, India; This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike Alike 4.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dermatology, Command Hospital Air Force, Bengaluru, Karnataka, India","institution_ids":["https://openalex.org/I4210153078"]},{"raw_affiliation_string":"1Consultant Dermatologist, Edappal Hospitals Pvt Limited, Kerala, India; 2Department of Dermatology, Sree Mookambika Institute of Medical Sciences, Kulasekharam, Kanyakumari, Tamil Nadu, India; 3Department of Dermatology, 7 Air Force Hospital, Kanpur, India; 4Department of Dermatology, Base Hospital, Lucknow, Uttar Pradesh, India; This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike Alike 4.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5107565001","display_name":"K Vivekanandh","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"K Vivekanandh","raw_affiliation_strings":["Consultant Dermatologist, Edappal Hospitals Pvt Limited, Kerala, India","1Consultant Dermatologist, Edappal Hospitals Pvt Limited, Kerala, India; 2Department of Dermatology, Sree Mookambika Institute of Medical Sciences, Kulasekharam, Kanyakumari, Tamil Nadu, India; 3Department of Dermatology, 7 Air Force Hospital, Kanpur, India; 4Department of Dermatology, Base Hospital, Lucknow, Uttar Pradesh, India; This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike Alike 4.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Consultant Dermatologist, Edappal Hospitals Pvt Limited, Kerala, India","institution_ids":[]},{"raw_affiliation_string":"1Consultant Dermatologist, Edappal Hospitals Pvt Limited, Kerala, India; 2Department of Dermatology, Sree Mookambika Institute of Medical Sciences, Kulasekharam, Kanyakumari, Tamil Nadu, India; 3Department of Dermatology, 7 Air Force Hospital, Kanpur, India; 4Department of Dermatology, Base Hospital, Lucknow, Uttar Pradesh, India; This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike Alike 4.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102923419","display_name":"Preema Sinha","orcid":"https://orcid.org/0000-0002-8771-828X","observed_orcids":["https://orcid.org/0000-0002-8771-828X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Preema Sinha","raw_affiliation_strings":["Department of Dermatology, 7 Air Force Hospital, Kanpur, India","1Consultant Dermatologist, Edappal Hospitals Pvt Limited, Kerala, India; 2Department of Dermatology, Sree Mookambika Institute of Medical Sciences, Kulasekharam, Kanyakumari, Tamil Nadu, India; 3Department of Dermatology, 7 Air Force Hospital, Kanpur, India; 4Department of Dermatology, Base Hospital, Lucknow, Uttar Pradesh, India; This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike Alike 4.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dermatology, 7 Air Force Hospital, Kanpur, India","institution_ids":[]},{"raw_affiliation_string":"1Consultant Dermatologist, Edappal Hospitals Pvt Limited, Kerala, India; 2Department of Dermatology, Sree Mookambika Institute of Medical Sciences, Kulasekharam, Kanyakumari, Tamil Nadu, India; 3Department of Dermatology, 7 Air Force Hospital, Kanpur, India; 4Department of Dermatology, Base Hospital, Lucknow, Uttar Pradesh, India; This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike Alike 4.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5059875354","display_name":"Anuj Kumar Bhatnagar","orcid":"https://orcid.org/0000-0003-3573-0348","observed_orcids":["https://orcid.org/0000-0003-3573-0348"]},"institutions":[{"id":"https://openalex.org/I4210153078","display_name":"Command Hospital Air Force","ror":"https://ror.org/05cx69s52","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I2801959050","https://openalex.org/I4210153078"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Anuj Bhatnagar","raw_affiliation_strings":["Department of Dermatology, Command Hospital Air Force, Bengaluru, Karnataka, India","1Consultant Dermatologist, Edappal Hospitals Pvt Limited, Kerala, India; 2Department of Dermatology, Sree Mookambika Institute of Medical Sciences, Kulasekharam, Kanyakumari, Tamil Nadu, India; 3Department of Dermatology, 7 Air Force Hospital, Kanpur, India; 4Department of Dermatology, Base Hospital, Lucknow, Uttar Pradesh, India; This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike Alike 4.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dermatology, Command Hospital Air Force, Bengaluru, Karnataka, India","institution_ids":["https://openalex.org/I4210153078"]},{"raw_affiliation_string":"1Consultant Dermatologist, Edappal Hospitals Pvt Limited, Kerala, India; 2Department of Dermatology, Sree Mookambika Institute of Medical Sciences, Kulasekharam, Kanyakumari, Tamil Nadu, India; 3Department of Dermatology, 7 Air Force Hospital, Kanpur, India; 4Department of Dermatology, Base Hospital, Lucknow, Uttar Pradesh, India; This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike Alike 4.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5066442707"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.4365,"has_fulltext":true,"cited_by_count":4,"citation_normalized_percentile":{"value":0.53333333,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":96},"biblio":{"volume":"14","issue":"3","first_page":"379","last_page":"379"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11725","display_name":"Immunodeficiency and Autoimmune Disorders","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11725","display_name":"Immunodeficiency and Autoimmune Disorders","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10837","display_name":"Dermatology and Skin Diseases","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12355","display_name":"Genetic and rare skin diseases.","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/primary-immunodeficiency","display_name":"primary immunodeficiency","score":0.7940000295639038},{"id":"https://openalex.org/keywords/atopic-dermatitis","display_name":"atopic dermatitis","score":0.9269999861717224},{"id":"https://openalex.org/keywords/recurrent-pulmonary-infection","display_name":"recurrent pulmonary infection","score":0.6600000262260437},{"id":"https://openalex.org/keywords/staphylococcal-skin-infections","display_name":"staphylococcal skin infections","score":0.9110000133514404},{"id":"https://openalex.org/keywords/serum-ige","display_name":"serum IgE","score":0.7390000224113464},{"id":"https://openalex.org/keywords/exon-deletion","display_name":"exon deletion","score":0.6520000100135803},{"id":"https://openalex.org/keywords/children","display_name":"children","score":0.5260000228881836},{"id":"https://openalex.org/keywords/diagnosis","display_name":"diagnosis","score":0.36800000071525574}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8567763566970825},{"id":"https://openalex.org/C141105273","wikidata":"https://www.wikidata.org/wiki/Q79455","display_name":"Immunoglobulin E","level":3,"score":0.7036731243133545},{"id":"https://openalex.org/C2778570526","wikidata":"https://www.wikidata.org/wiki/Q653197","display_name":"Rash","level":2,"score":0.6613002419471741},{"id":"https://openalex.org/C2778329239","wikidata":"https://www.wikidata.org/wiki/Q268667","display_name":"Atopic dermatitis","level":2,"score":0.5322978496551514},{"id":"https://openalex.org/C2779019163","wikidata":"https://www.wikidata.org/wiki/Q3043160","display_name":"Primary immunodeficiency","level":3,"score":0.5216677188873291},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.5062090754508972},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.4858262538909912},{"id":"https://openalex.org/C2910733768","wikidata":"https://www.wikidata.org/wiki/Q229256","display_name":"Eczematous dermatitis","level":2,"score":0.47863736748695374},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.38516169786453247},{"id":"https://openalex.org/C16005928","wikidata":"https://www.wikidata.org/wiki/Q171171","display_name":"Dermatology","level":1,"score":0.27946290373802185},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.09719890356063843}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.4103/idoj.idoj_472_22","doi":"https://doi.org/10.4103/idoj.idoj_472_22","is_oa":true,"landing_page_url":"https://doi.org/10.4103/idoj.idoj_472_22","pdf_url":null,"source":{"id":"https://openalex.org/S2754097677","display_name":"Indian Dermatology Online Journal","issn_l":"2229-5178","issn":["2229-5178","2249-5673"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","doyens","ki-jl-1","poland-20","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320448","host_organization_name":"Medknow","host_organization_lineage":["https://openalex.org/P4310320448","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Medknow","Wolters Kluwer"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Indian Dermatology Online Journal","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:10231702","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10231702","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10231702/pdf/IDOJ-14-379.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Indian Dermatol Online J","raw_type":"Text"},{"id":"pmid:37266097","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37266097","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Indian dermatology online journal","raw_type":"Case Reports"},{"id":"pmh:oai:doaj.org/article:e9dc66c0f3f74a1087b809206bdca087","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/e9dc66c0f3f74a1087b809206bdca087","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Indian Dermatology Online Journal, Vol 14, Iss 3, Pp 379-382 (2023)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.4103/idoj.idoj_472_22","doi":"https://doi.org/10.4103/idoj.idoj_472_22","is_oa":true,"landing_page_url":"https://doi.org/10.4103/idoj.idoj_472_22","pdf_url":null,"source":{"id":"https://openalex.org/S2754097677","display_name":"Indian Dermatology Online Journal","issn_l":"2229-5178","issn":["2229-5178","2249-5673"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","doyens","ki-jl-1","poland-20","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320448","host_organization_name":"Medknow","host_organization_lineage":["https://openalex.org/P4310320448","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Medknow","Wolters Kluwer"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Indian Dermatology Online Journal","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/case-report","display_name":"Case Report"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":10,"referenced_works":["https://openalex.org/W1596039759","https://openalex.org/W1972868972","https://openalex.org/W2050152285","https://openalex.org/W2053401301","https://openalex.org/W2097149586","https://openalex.org/W2162721157","https://openalex.org/W2329293925","https://openalex.org/W2755141428","https://openalex.org/W2796216811","https://openalex.org/W3135200627"],"related_works":["https://openalex.org/W2948564549","https://openalex.org/W7202374759","https://openalex.org/W2342986091","https://openalex.org/W4386703830","https://openalex.org/W7125791492","https://openalex.org/W2738311728","https://openalex.org/W2292971120","https://openalex.org/W2075367037","https://openalex.org/W7120704049","https://openalex.org/W1969988509"],"abstract_inverted_index":{"Hyper-immunoglobulin":[0],"E":[1,110],"syndrome":[2,8,111,133],"is":[3,112,157],"a":[4,23,46],"rare":[5,132],"primary":[6],"immunodeficiency":[7],"characterized":[9],"by":[10],"severe":[11],"atopic":[12],"dermatitis,":[13],"recurrent":[14,60],"pulmonary":[15,70],"and":[16,31,72,117,128,144],"staphylococcal":[17],"skin":[18,119],"infections.":[19],"Its":[20],"diagnosis":[21],"requires":[22],"high":[24],"degree":[25],"of":[26,67,85,93,106,108,115,130,137,149],"suspicion,":[27],"typical":[28],"clinical":[29],"features,":[30],"not":[32,42],"mere":[33],"rise":[34],"in":[35,45,50,82,100,159],"serum":[36,74],"IgE":[37,75],"levels.":[38,76],"Genetic":[39],"studies":[40],"are":[41],"always":[43],"possible":[44],"resource":[47],"poor":[48],"setting":[49],"developing":[51],"countries.":[52],"In":[53],"this":[54,131],"case":[55,122],"series,":[56],"all":[57],"children":[58],"had":[59],"eczematoid":[61],"rash,":[62],"secondary":[63],"infections,":[64],"multiple":[65],"episodes":[66],"hospitalization":[68],"for":[69],"infection":[71],"raised":[73],"Diagnostic":[77],"genetic":[78],"study":[79],"was":[80],"feasible":[81],"only":[83],"one":[84],"the":[86,155],"cases":[87],"which":[88],"revealed":[89],"pathogenic":[90],"homozygous":[91],"deletions":[92],"exons":[94],"15":[95],"to":[96,146],"18":[97],"(Transcript:":[98],"NM_203447)":[99],"DOCK8":[101],"gene.":[102],"The":[103],"main":[104],"goal":[105],"management":[107,129],"hyper-immunoglobulin":[109],"aggressive":[113],"treatment":[114],"infections":[116],"optimum":[118],"care.":[120],"Our":[121],"series":[123],"highlights":[124],"various":[125],"characteristic,":[126],"presentations,":[127],"childhood":[134],"cases.":[135],"Awareness":[136],"these":[138],"manifestations":[139],"may":[140],"facilitate":[141],"early":[142],"identification":[143],"contribute":[145],"optimal":[147],"care":[148],"patients":[150],"as":[151],"representative":[152],"data":[153],"on":[154],"same":[156],"limited":[158],"literature.":[160]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":2}],"updated_date":"2026-10-29T09:56:32.521200","created_date":"2023-04-30T00:00:00"}