{"id":"https://openalex.org/W4367331399","doi":"https://doi.org/10.15407/cryo32.04.277","title":"Lyophilized Human Cord Blood Leukoconcentrate Affects Immune System of Rats with Ischemic Stroke","display_name":"Lyophilized Human Cord Blood Leukoconcentrate Affects Immune System of Rats with Ischemic Stroke","publication_year":2022,"publication_date":"2022-12-30","ids":{"openalex":"https://openalex.org/W4367331399","doi":"https://doi.org/10.15407/cryo32.04.277"},"language":"en","primary_location":{"id":"doi:10.15407/cryo32.04.277","doi":"https://doi.org/10.15407/cryo32.04.277","is_oa":true,"landing_page_url":"https://doi.org/10.15407/cryo32.04.277","pdf_url":"http://cryo.org.ua/journal/index.php/probl-cryobiol-cryomed/article/download/1823/1936","source":{"id":"https://openalex.org/S2764351852","display_name":"Problems of Cryobiology and Cryomedicine","issn_l":"2307-6143","issn":["2307-6143","2518-7376"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":["poland-20","russia-white-list-4"],"host_organization":"https://openalex.org/I4210166931","host_organization_name":"Institute for Problems of Cryobiology and Cryomedicine","host_organization_lineage":["https://openalex.org/I4210166931"],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Problems of Cryobiology and Cryomedicine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"http://cryo.org.ua/journal/index.php/probl-cryobiol-cryomed/article/download/1823/1936","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5052573467","display_name":"V. Lebedynets","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I149851306","display_name":"National Academy of Sciences of Ukraine","ror":"https://ror.org/00je4t102","country_code":"UA","type":"government","lineage":["https://openalex.org/I149851306"]},{"id":"https://openalex.org/I4210166931","display_name":"Institute for Problems of Cryobiology and Cryomedicine","ror":"https://ror.org/05sczh171","country_code":"UA","type":"facility","lineage":["https://openalex.org/I149851306","https://openalex.org/I4210166931"]},{"id":"https://openalex.org/I8765205","display_name":"V. N. Karazin Kharkiv National University","ror":"https://ror.org/03ftejk10","country_code":"UA","type":"education","lineage":["https://openalex.org/I8765205"]}],"countries":["UA"],"is_corresponding":false,"raw_author_name":"Volodymyr Lebedynets","raw_affiliation_strings":["Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv;   V.N. Karazin Kharkiv National University, Kharkiv","Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv","V.N. Karazin Kharkiv National University, Kharkiv"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv;   V.N. Karazin Kharkiv National University, Kharkiv","institution_ids":["https://openalex.org/I149851306","https://openalex.org/I4210166931","https://openalex.org/I8765205"]},{"raw_affiliation_string":"Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv","institution_ids":["https://openalex.org/I4210166931"]},{"raw_affiliation_string":"V.N. Karazin Kharkiv National University, Kharkiv","institution_ids":["https://openalex.org/I8765205"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001337814","display_name":"Ludmila Ostankova","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210166931","display_name":"Institute for Problems of Cryobiology and Cryomedicine","ror":"https://ror.org/05sczh171","country_code":"UA","type":"facility","lineage":["https://openalex.org/I149851306","https://openalex.org/I4210166931"]}],"countries":["UA"],"is_corresponding":false,"raw_author_name":"Ludmila Ostankova","raw_affiliation_strings":["Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv","institution_ids":["https://openalex.org/I4210166931"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090447963","display_name":"Mykola O. Bondarovych","orcid":"https://orcid.org/0000-0001-7977-0283","observed_orcids":["https://orcid.org/0000-0001-7977-0283"]},"institutions":[{"id":"https://openalex.org/I4210166931","display_name":"Institute for Problems of Cryobiology and Cryomedicine","ror":"https://ror.org/05sczh171","country_code":"UA","type":"facility","lineage":["https://openalex.org/I149851306","https://openalex.org/I4210166931"]}],"countries":["UA"],"is_corresponding":false,"raw_author_name":"Mykola Bondarovych","raw_affiliation_strings":["Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv"],"raw_orcid":"https://orcid.org/0000-0001-7977-0283","affiliations":[{"raw_affiliation_string":"Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv","institution_ids":["https://openalex.org/I4210166931"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089404927","display_name":"Dmytro Lebedynets","orcid":"https://orcid.org/0000-0001-8508-9208","observed_orcids":["https://orcid.org/0000-0001-8508-9208"]},"institutions":[{"id":"https://openalex.org/I8765205","display_name":"V. N. Karazin Kharkiv National University","ror":"https://ror.org/03ftejk10","country_code":"UA","type":"education","lineage":["https://openalex.org/I8765205"]}],"countries":["UA"],"is_corresponding":false,"raw_author_name":"Dmytro Lebedynets","raw_affiliation_strings":["V.N. Karazin Kharkiv National University, Kharkiv"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"V.N. Karazin Kharkiv National University, Kharkiv","institution_ids":["https://openalex.org/I8765205"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083233956","display_name":"Maksim V. Ostankov","orcid":"https://orcid.org/0000-0001-8412-5262","observed_orcids":["https://orcid.org/0000-0001-8412-5262"]},"institutions":[{"id":"https://openalex.org/I4210166931","display_name":"Institute for Problems of Cryobiology and Cryomedicine","ror":"https://ror.org/05sczh171","country_code":"UA","type":"facility","lineage":["https://openalex.org/I149851306","https://openalex.org/I4210166931"]}],"countries":["UA"],"is_corresponding":false,"raw_author_name":"Maksym Ostankov","raw_affiliation_strings":["Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv"],"raw_orcid":"https://orcid.org/0000-0001-8412-5262","affiliations":[{"raw_affiliation_string":"Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv","institution_ids":["https://openalex.org/I4210166931"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025776710","display_name":"Olena D. Lutsenko","orcid":"https://orcid.org/0000-0003-3982-9687","observed_orcids":["https://orcid.org/0000-0003-3982-9687"]},"institutions":[{"id":"https://openalex.org/I149851306","display_name":"National Academy of Sciences of Ukraine","ror":"https://ror.org/00je4t102","country_code":"UA","type":"government","lineage":["https://openalex.org/I149851306"]},{"id":"https://openalex.org/I4210144782","display_name":"National Academy of Medical Sciences of Ukraine","ror":"https://ror.org/042dnf796","country_code":"UA","type":"government","lineage":["https://openalex.org/I4210144782"]},{"id":"https://openalex.org/I4210166931","display_name":"Institute for Problems of Cryobiology and Cryomedicine","ror":"https://ror.org/05sczh171","country_code":"UA","type":"facility","lineage":["https://openalex.org/I149851306","https://openalex.org/I4210166931"]}],"countries":["UA"],"is_corresponding":false,"raw_author_name":"Olena Lutsenko","raw_affiliation_strings":["Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv; Interdepartmental Scientific Center for Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Academy of Medical Sciences and Ministry of Health Care of Ukraine, Kharkiv","Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv","Interdepartmental Scientific Center for Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Academy of Medical Sciences and Ministry of Health Care of Ukraine, Kharkiv"],"raw_orcid":"https://orcid.org/0000-0003-3982-9687","affiliations":[{"raw_affiliation_string":"Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv; Interdepartmental Scientific Center for Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Academy of Medical Sciences and Ministry of Health Care of Ukraine, Kharkiv","institution_ids":["https://openalex.org/I149851306","https://openalex.org/I4210166931"]},{"raw_affiliation_string":"Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv","institution_ids":["https://openalex.org/I4210166931"]},{"raw_affiliation_string":"Interdepartmental Scientific Center for Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Academy of Medical Sciences and Ministry of Health Care of Ukraine, Kharkiv","institution_ids":["https://openalex.org/I149851306","https://openalex.org/I4210144782"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065568465","display_name":"Igor G. Grisha","orcid":"https://orcid.org/0000-0003-2875-910X","observed_orcids":["https://orcid.org/0000-0003-2875-910X"]},"institutions":[{"id":"https://openalex.org/I4210166931","display_name":"Institute for Problems of Cryobiology and Cryomedicine","ror":"https://ror.org/05sczh171","country_code":"UA","type":"facility","lineage":["https://openalex.org/I149851306","https://openalex.org/I4210166931"]}],"countries":["UA"],"is_corresponding":false,"raw_author_name":"Igor Grisha","raw_affiliation_strings":["Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv"],"raw_orcid":"https://orcid.org/0000-0003-2875-910X","affiliations":[{"raw_affiliation_string":"Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv","institution_ids":["https://openalex.org/I4210166931"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5065161671","display_name":"\u0410natoliy Goltsev","orcid":"https://orcid.org/0000-0002-5289-5876","observed_orcids":["https://orcid.org/0000-0002-5289-5876"]},"institutions":[{"id":"https://openalex.org/I149851306","display_name":"National Academy of Sciences of Ukraine","ror":"https://ror.org/00je4t102","country_code":"UA","type":"government","lineage":["https://openalex.org/I149851306"]},{"id":"https://openalex.org/I4210109132","display_name":"Ministry of Health","ror":"https://ror.org/01sxtx626","country_code":"UA","type":"government","lineage":["https://openalex.org/I4210109132"]},{"id":"https://openalex.org/I4210144782","display_name":"National Academy of Medical Sciences of Ukraine","ror":"https://ror.org/042dnf796","country_code":"UA","type":"government","lineage":["https://openalex.org/I4210144782"]},{"id":"https://openalex.org/I4210166931","display_name":"Institute for Problems of Cryobiology and Cryomedicine","ror":"https://ror.org/05sczh171","country_code":"UA","type":"facility","lineage":["https://openalex.org/I149851306","https://openalex.org/I4210166931"]}],"countries":["UA"],"is_corresponding":false,"raw_author_name":"Anatoliy Goltsev","raw_affiliation_strings":["Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv; Interdepartmental Scientific Center of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Academy of Medical Sciences of Ukraine and Ministry of Health of Ukraine","Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv","Interdepartmental Scientific Center of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Academy of Medical Sciences of Ukraine and Ministry of Health of Ukraine"],"raw_orcid":"https://orcid.org/0000-0002-5289-5876","affiliations":[{"raw_affiliation_string":"Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv; Interdepartmental Scientific Center of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Academy of Medical Sciences of Ukraine and Ministry of Health of Ukraine","institution_ids":["https://openalex.org/I149851306","https://openalex.org/I4210109132","https://openalex.org/I4210144782","https://openalex.org/I4210166931"]},{"raw_affiliation_string":"Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv","institution_ids":["https://openalex.org/I4210166931"]},{"raw_affiliation_string":"Interdepartmental Scientific Center of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Academy of Medical Sciences of Ukraine and Ministry of Health of Ukraine","institution_ids":["https://openalex.org/I149851306","https://openalex.org/I4210109132","https://openalex.org/I4210144782"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.1928,"has_fulltext":true,"cited_by_count":3,"citation_normalized_percentile":{"value":0.32919955,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"32","issue":"4","first_page":"277","last_page":"291"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10176","display_name":"Mesenchymal stem cell research","score":0.8213000297546387,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10176","display_name":"Mesenchymal stem cell research","score":0.8213000297546387,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11266","display_name":"Neuroinflammation and Neurodegeneration Mechanisms","score":0.05719999969005585,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10227","display_name":"Acute Ischemic Stroke Management","score":0.04360000044107437,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ischemic-stroke","display_name":"ischemic stroke","score":0.9670000076293945},{"id":"https://openalex.org/keywords/freeze-drying","display_name":"freeze-drying","score":0.8690000176429749},{"id":"https://openalex.org/keywords/cryopreservation","display_name":"cryopreservation","score":0.9990000128746033},{"id":"https://openalex.org/keywords/immunomodulation","display_name":"immunomodulation","score":0.7789999842643738},{"id":"https://openalex.org/keywords/lymphocyte-subsets","display_name":"lymphocyte subsets","score":0.6029999852180481},{"id":"https://openalex.org/keywords/immunoglobulins","display_name":"immunoglobulins","score":0.8560000061988831},{"id":"https://openalex.org/keywords/circulating-immune-complexes","display_name":"circulating immune complexes","score":0.8640000224113464},{"id":"https://openalex.org/keywords/middle-cerebral-artery-occlusion","display_name":"middle cerebral artery occlusion","score":0.906000018119812},{"id":"https://openalex.org/keywords/cell-therapy","display_name":"cell therapy","score":0.5740000009536743},{"id":"https://openalex.org/keywords/neurodegenerative-diseases","display_name":"neurodegenerative diseases","score":0.652999997138977}],"concepts":[{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.8045133352279663},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6211408376693726},{"id":"https://openalex.org/C179933525","wikidata":"https://www.wikidata.org/wiki/Q1144664","display_name":"Cryopreservation","level":3,"score":0.6118837594985962},{"id":"https://openalex.org/C2780914630","wikidata":"https://www.wikidata.org/wiki/Q914952","display_name":"Cord blood","level":2,"score":0.5873115062713623},{"id":"https://openalex.org/C2780645631","wikidata":"https://www.wikidata.org/wiki/Q671554","display_name":"Stroke (engine)","level":2,"score":0.535304844379425},{"id":"https://openalex.org/C167672396","wikidata":"https://www.wikidata.org/wiki/Q417800","display_name":"CD8","level":3,"score":0.5034021735191345},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.4593120217323303},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.42109888792037964},{"id":"https://openalex.org/C2781462264","wikidata":"https://www.wikidata.org/wiki/Q78482053","display_name":"CD16","level":5,"score":0.41713446378707886},{"id":"https://openalex.org/C16685009","wikidata":"https://www.wikidata.org/wiki/Q335057","display_name":"Andrology","level":1,"score":0.3337790369987488},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.3300866484642029},{"id":"https://openalex.org/C114684123","wikidata":"https://www.wikidata.org/wiki/Q419458","display_name":"CD3","level":4,"score":0.31872305274009705},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2537369132041931},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.05769240856170654},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C78519656","wikidata":"https://www.wikidata.org/wiki/Q101333","display_name":"Mechanical engineering","level":1,"score":0.0},{"id":"https://openalex.org/C196843134","wikidata":"https://www.wikidata.org/wiki/Q33196","display_name":"Embryo","level":2,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.15407/cryo32.04.277","doi":"https://doi.org/10.15407/cryo32.04.277","is_oa":true,"landing_page_url":"https://doi.org/10.15407/cryo32.04.277","pdf_url":"http://cryo.org.ua/journal/index.php/probl-cryobiol-cryomed/article/download/1823/1936","source":{"id":"https://openalex.org/S2764351852","display_name":"Problems of Cryobiology and Cryomedicine","issn_l":"2307-6143","issn":["2307-6143","2518-7376"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":["poland-20","russia-white-list-4"],"host_organization":"https://openalex.org/I4210166931","host_organization_name":"Institute for Problems of Cryobiology and Cryomedicine","host_organization_lineage":["https://openalex.org/I4210166931"],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Problems of Cryobiology and Cryomedicine","raw_type":"journal-article"},{"id":"pmh:oai:cryo.org.ua/journal:article/1823","doi":null,"is_oa":true,"landing_page_url":"https://cryo.org.ua/journal/index.php/probl-cryobiol-cryomed/article/view/1823","pdf_url":"https://cryo.org.ua/journal/index.php/probl-cryobiol-cryomed/article/download/1823/1936","source":{"id":"https://openalex.org/S2764351852","display_name":"Problems of Cryobiology and Cryomedicine","issn_l":"2307-6143","issn":["2307-6143","2518-7376"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":["poland-20","russia-white-list-4"],"host_organization":"https://openalex.org/I4210166931","host_organization_name":"Institute for Problems of Cryobiology and Cryomedicine","host_organization_lineage":["https://openalex.org/I4210166931"],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2307-6143","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.15407/cryo32.04.277","doi":"https://doi.org/10.15407/cryo32.04.277","is_oa":true,"landing_page_url":"https://doi.org/10.15407/cryo32.04.277","pdf_url":"http://cryo.org.ua/journal/index.php/probl-cryobiol-cryomed/article/download/1823/1936","source":{"id":"https://openalex.org/S2764351852","display_name":"Problems of Cryobiology and Cryomedicine","issn_l":"2307-6143","issn":["2307-6143","2518-7376"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":["poland-20","russia-white-list-4"],"host_organization":"https://openalex.org/I4210166931","host_organization_name":"Institute for Problems of Cryobiology and Cryomedicine","host_organization_lineage":["https://openalex.org/I4210166931"],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Problems of Cryobiology and Cryomedicine","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.98580002784729}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4367331399.pdf","grobid_xml":"https://content.openalex.org/works/W4367331399.grobid-xml"},"referenced_works_count":14,"referenced_works":["https://openalex.org/W1983719979","https://openalex.org/W2009188732","https://openalex.org/W2091594252","https://openalex.org/W2504472607","https://openalex.org/W2545427057","https://openalex.org/W2810407838","https://openalex.org/W2928435510","https://openalex.org/W2932292204","https://openalex.org/W2945642944","https://openalex.org/W2980352503","https://openalex.org/W2994839377","https://openalex.org/W3000460228","https://openalex.org/W3116738485","https://openalex.org/W4281748999"],"related_works":["https://openalex.org/W7217734739","https://openalex.org/W4281748999","https://openalex.org/W3013032377","https://openalex.org/W2771928680","https://openalex.org/W4282043618","https://openalex.org/W2995023786","https://openalex.org/W2886069599","https://openalex.org/W1575773419","https://openalex.org/W7215606555","https://openalex.org/W2406890068"],"abstract_inverted_index":{"Cerebrovascular":[0],"pathology,":[1],"especially":[2],"acute":[3],"cerebrovascular":[4],"accident":[5],"is":[6],"among":[7],"the":[8,15,35,72,103,114,139,196],"most":[9],"complicated":[10],"issues":[11],"in":[12,65,94,149,185,200],"medicine.":[13],"Therefore,":[14],"search":[16],"for":[17],"efficient":[18],"ways":[19],"to":[20,137],"treat":[21],"neurodegenerative":[22],"diseases":[23],"has":[24,56,171],"still":[25],"remained":[26],"topical.":[27],"In":[28,100],"experimental":[29,126],"model":[30,127],"of":[31,37,71,86,89,107,116,128,135,141,144,155,161,176,188,195],"ischemic":[32,61],"stroke":[33,62],"(IS),":[34],"impact":[36],"lyophilized":[38],"and":[39,46,53,78,105,119,133,157,165,182],"cryopreserved":[40],"human":[41],"cord":[42],"blood":[43,101],"leukoconcentrate":[44],"(lHCBL":[45],"cHCBL,":[47],"respectively)":[48],"on":[49,159],"immune":[50,121,162,197],"system":[51,163,198],"humoral":[52,166],"cell":[54,164],"components":[55,167],"been":[57,172],"comparatively":[58],"studied.":[59],"The":[60,76,125,174],"was":[63,147],"simulated":[64],"6-monthold":[66],"Wistar":[67],"rats":[68],"by":[69],"occlusion":[70],"middle":[73],"cerebral":[74],"artery.":[75],"lHCBL":[77,156],"cHCBL":[79,158,181],"were":[80,123],"administered":[81],"intraperitoneally":[82],"at":[83],"a":[84,191],"dose":[85],"0.5":[87],"ml":[88],"5":[90],"\u00d7":[91],"106":[92],"cells":[93],"6":[95],"hrs":[96],"after":[97],"surgery":[98],"(occlusion).":[99],"serum,":[102],"populations":[104],"subpopulations":[106],"lymphocytes":[108],"(CD3+,":[109],"CD4+,":[110],"CD8+,":[111],"CD16+,":[112],"CD4+CD25+),":[113],"content":[115],"total":[117],"immunoglobulins":[118],"circulating":[120],"complexes":[122],"determined.":[124],"IS":[129,169,189],"showed":[130],"both":[131],"lyophilization":[132],"cryopreservation":[134],"HCBL":[136,184],"ensure":[138],"preservation":[140],"immunomodulatory":[142],"potential":[143],"cells,":[145],"that":[146],"confirmed":[148],"vivo.":[150],"An":[151],"equivalent":[152],"corrective":[153],"effect":[154],"indices":[160,199],"during":[168],"development":[170],"established.":[173],"inclusion":[175],"lHCBL,":[177],"as":[178,180],"well":[179],"native":[183],"basic":[186],"therapy":[187],"promoted":[190],"more":[192],"rapid":[193],"recovery":[194],"animals.":[201]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2023-04-30T00:00:00"}