{"id":"https://openalex.org/W4366740104","doi":"https://doi.org/10.1093/jnci/71.1.25","title":"Evaluation of a Radioimmunoassay for \u03b11-Acid Glycoprotein To Monitor Therapy of Cancer Patients 2 3","display_name":"Evaluation of a Radioimmunoassay for \u03b11-Acid Glycoprotein To Monitor Therapy of Cancer Patients 2 3","publication_year":1983,"publication_date":"1983-07-01","ids":{"openalex":"https://openalex.org/W4366740104","doi":"https://doi.org/10.1093/jnci/71.1.25","mag":"2336483923","pmid":"https://pubmed.ncbi.nlm.nih.gov/6575206"},"language":"en","primary_location":{"id":"doi:10.1093/jnci/71.1.25","doi":"https://doi.org/10.1093/jnci/71.1.25","is_oa":false,"landing_page_url":"https://doi.org/10.1093/jnci/71.1.25","pdf_url":null,"source":{"id":"https://openalex.org/S98010888","display_name":"JNCI Journal of the National Cancer Institute","issn_l":"0027-8874","issn":["0027-8874","1460-2105"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JNCI: Journal of the National Cancer Institute","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5103153387","display_name":"Patricia A. Ganz","orcid":"https://orcid.org/0000-0002-1841-4143","observed_orcids":["https://orcid.org/0000-0002-1841-4143"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Patricia A. Ganz, M.D.","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066125203","display_name":"William E. Shell","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"William E. Shell, M.D.","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5069416627","display_name":"Zolt\u00e1n A. T\u00f6k\u00e9s","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Zolt\u00e1n A. T\u00f6k\u00e9s, Ph.D.","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":5436,"currency":"USD","value_usd":5436},"apc_paid":null,"fwci":0.9947,"has_fulltext":false,"cited_by_count":31,"citation_normalized_percentile":{"value":0.79474295,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"71","issue":"1","first_page":"25","last_page":"30"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11355","display_name":"Inflammatory Biomarkers in Disease Prognosis","score":0.7813000082969666,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11355","display_name":"Inflammatory Biomarkers in Disease Prognosis","score":0.7813000082969666,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12379","display_name":"Cancer Diagnosis and Treatment","score":0.05900000035762787,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12322","display_name":"Animal health and immunology","score":0.033399999141693115,"subfield":{"id":"https://openalex.org/subfields/1103","display_name":"Animal Science and Zoology"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/alpha-1-acid-glycoprotein","display_name":"alpha-1-acid glycoprotein","score":0.9039999842643738},{"id":"https://openalex.org/keywords/radioimmunoassay","display_name":"radioimmunoassay","score":0.9190000295639038},{"id":"https://openalex.org/keywords/tumor-markers","display_name":"tumor markers","score":0.6819999814033508},{"id":"https://openalex.org/keywords/cancer-therapy-monitoring","display_name":"cancer treatment monitoring","score":0.8270000219345093},{"id":"https://openalex.org/keywords/plasma-protein-levels","display_name":"plasma protein levels","score":0.7179999947547913},{"id":"https://openalex.org/keywords/solid-tumors","display_name":"solid tumors","score":0.9819999933242798},{"id":"https://openalex.org/keywords/hematologic-malignancies","display_name":"hematologic malignancies","score":0.9940000176429749},{"id":"https://openalex.org/keywords/small-cell-lung-cancer","display_name":"small cell lung cancer","score":0.9330000281333923},{"id":"https://openalex.org/keywords/colon-cancer","display_name":"colon cancer","score":0.9419999718666077},{"id":"https://openalex.org/keywords/lymphoma","display_name":"lymphoma","score":0.9940000176429749},{"id":"https://openalex.org/keywords/non-small-cell-lung-cancer","display_name":"non-small cell lung cancer","score":0.9340000152587891},{"id":"https://openalex.org/keywords/metastatic-cancer","display_name":"metastatic cancer","score":0.906000018119812}],"concepts":[{"id":"https://openalex.org/C176685330","wikidata":"https://www.wikidata.org/wiki/Q857638","display_name":"Radioimmunoassay","level":2,"score":0.8262510299682617},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7502561807632446},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.6558047533035278},{"id":"https://openalex.org/C2776256026","wikidata":"https://www.wikidata.org/wiki/Q47912","display_name":"Lung cancer","level":2,"score":0.6183891296386719},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6031664609909058},{"id":"https://openalex.org/C108625454","wikidata":"https://www.wikidata.org/wiki/Q187126","display_name":"Glycoprotein","level":2,"score":0.5188285708427429},{"id":"https://openalex.org/C2779338263","wikidata":"https://www.wikidata.org/wiki/Q208414","display_name":"Lymphoma","level":2,"score":0.5140095949172974},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.36392390727996826},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.3356436491012573},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.12532994151115417},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.06788939237594604}],"mesh":[{"descriptor_ui":"D005069","descriptor_name":"Evaluation Studies as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005770","descriptor_name":"Gastrointestinal Neoplasms","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007938","descriptor_name":"Leukemia","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D007938","descriptor_name":"Leukemia","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D008223","descriptor_name":"Lymphoma","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D008223","descriptor_name":"Lymphoma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D009961","descriptor_name":"Orosomucoid","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D011863","descriptor_name":"Radioimmunoassay","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1093/jnci/71.1.25","doi":"https://doi.org/10.1093/jnci/71.1.25","is_oa":false,"landing_page_url":"https://doi.org/10.1093/jnci/71.1.25","pdf_url":null,"source":{"id":"https://openalex.org/S98010888","display_name":"JNCI Journal of the National Cancer Institute","issn_l":"0027-8874","issn":["0027-8874","1460-2105"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JNCI: Journal of the National Cancer Institute","raw_type":"journal-article"},{"id":"pmid:6575206","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/6575206","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the National Cancer Institute","raw_type":"Journal Article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.924.4318","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.924.4318","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://jnci.oxfordjournals.org/content/71/1/25.full.pdf","raw_type":"text"},{"id":"mag:2336483923","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/6575206","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2336483923","https://openalex.org/W7099782350","https://openalex.org/W2429319696","https://openalex.org/W2606793825","https://openalex.org/W2283149094","https://openalex.org/W7113751348","https://openalex.org/W7208640033","https://openalex.org/W2972770655","https://openalex.org/W2067674360","https://openalex.org/W113923349"],"abstract_inverted_index":{"A":[0],"new":[1],"radioimmunoassay":[2],"for":[3,8,102],"alpha":[4],"1-acid":[5],"glycoprotein":[6,21],"(AGP)":[7],"monitoring":[9,103],"the":[10,56,63],"therapy":[11,104],"of":[12,19,49,55,62,79,92,97],"cancer":[13,85],"patients":[14,30,37,43,59,64,80],"was":[15],"evaluated.":[16],"Plasma":[17,47],"levels":[18,48],"this":[20],"were":[22,51],"measured":[23],"in":[24,53,105],"49":[25],"normal":[26,87],"healthy":[27],"volunteers,":[28],"71":[29],"with":[31,38,44,65,81],"illnesses":[32,82],"other":[33,83],"than":[34,84],"cancer,":[35,112,114],"190":[36],"solid":[39,57],"tumors,":[40],"and":[41,60,86,116],"58":[42],"hematologic":[45,66],"neoplasms.":[46],"AGP":[50,98],"elevated":[52],"89%":[54],"tumor":[58,107],"87%":[61],"neoplasms":[67],"who":[68],"had":[69,90],"newly":[70],"diagnosed,":[71],"locally":[72],"recurrent,":[73],"or":[74],"metastatic":[75],"cancer.":[76,119],"Only":[77],"18%":[78],"renal":[88],"function":[89],"elevations":[91],"plasma":[93],"AGP.":[94],"Serial":[95],"measurements":[96],"may":[99],"be":[100],"useful":[101],"several":[106],"types,":[108],"including":[109],"small-cell":[110],"lung":[111,118],"colon":[113],"lymphoma,":[115],"non-small-cell":[117]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2023-04-24T00:00:00"}