{"id":"https://openalex.org/W4366262986","doi":"https://doi.org/10.1016/j.tacc.2023.101238","title":"High flow nasal oxygen (HFNO) in the treatment of COVID-19 infection of adult patients from \u2013 An emergency perspective: A systematic review and meta-analysis","display_name":"High flow nasal oxygen (HFNO) in the treatment of COVID-19 infection of adult patients from \u2013 An emergency perspective: A systematic review and meta-analysis","publication_year":2023,"publication_date":"2023-04-18","ids":{"openalex":"https://openalex.org/W4366262986","doi":"https://doi.org/10.1016/j.tacc.2023.101238","pmid":"https://pubmed.ncbi.nlm.nih.gov/38620122","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/10111871"},"language":"en","primary_location":{"id":"doi:10.1016/j.tacc.2023.101238","doi":"https://doi.org/10.1016/j.tacc.2023.101238","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.tacc.2023.101238","pdf_url":null,"source":{"id":"https://openalex.org/S2764716574","display_name":"Trends in Anaesthesia and Critical Care","issn_l":"2210-8440","issn":["2210-8440","2210-8467"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","norway-1","poland-40","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Trends in Anaesthesia and Critical Care","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","datacite","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1016/j.tacc.2023.101238","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5077482722","display_name":"Nabil Adbelhamid Shallik","orcid":"https://orcid.org/0000-0002-8247-4394","observed_orcids":["https://orcid.org/0000-0002-8247-4394"]},"institutions":[{"id":"https://openalex.org/I21376657","display_name":"Tanta University","ror":"https://ror.org/016jp5b92","country_code":"EG","type":"education","lineage":["https://openalex.org/I21376657"]},{"id":"https://openalex.org/I4210152471","display_name":"Weill Cornell Medical College in Qatar","ror":"https://ror.org/05v5hg569","country_code":"QA","type":"education","lineage":["https://openalex.org/I4210152471"]},{"id":"https://openalex.org/I49828101","display_name":"Hamad Medical Corporation","ror":"https://ror.org/02zwb6n98","country_code":"QA","type":"nonprofit","lineage":["https://openalex.org/I49828101"]},{"id":"https://openalex.org/I60342839","display_name":"Qatar University","ror":"https://ror.org/00yhnba62","country_code":"QA","type":"education","lineage":["https://openalex.org/I60342839"]}],"countries":["EG","QA"],"is_corresponding":true,"raw_author_name":"Nabil Shallik","raw_affiliation_strings":["Anaesthesia, ICU and Perioperative Medicine Department, Hamad Medical Corporation, Doha, Qatar","Clinical Anaesthesia Department, College of Medicine Qatar University, Doha, Qatar","Clinical Anaesthesia Department, Weill Cornell Medical College in Qatar, Doha, Qatar","Clinical Anaesthesia and SICU Department, Tanta University, Tanta, Egypt"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Anaesthesia, ICU and Perioperative Medicine Department, Hamad Medical Corporation, Doha, Qatar","institution_ids":["https://openalex.org/I49828101"]},{"raw_affiliation_string":"Clinical Anaesthesia Department, College of Medicine Qatar University, Doha, Qatar","institution_ids":["https://openalex.org/I60342839"]},{"raw_affiliation_string":"Clinical Anaesthesia Department, Weill Cornell Medical College in Qatar, Doha, Qatar","institution_ids":["https://openalex.org/I4210152471"]},{"raw_affiliation_string":"Clinical Anaesthesia and SICU Department, Tanta University, Tanta, Egypt","institution_ids":["https://openalex.org/I21376657"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056120119","display_name":"Khalid Bashir","orcid":"https://orcid.org/0000-0003-4213-4667","observed_orcids":["https://orcid.org/0000-0003-4213-4667"]},"institutions":[{"id":"https://openalex.org/I49828101","display_name":"Hamad Medical Corporation","ror":"https://ror.org/02zwb6n98","country_code":"QA","type":"nonprofit","lineage":["https://openalex.org/I49828101"]},{"id":"https://openalex.org/I60342839","display_name":"Qatar University","ror":"https://ror.org/00yhnba62","country_code":"QA","type":"education","lineage":["https://openalex.org/I60342839"]}],"countries":["QA"],"is_corresponding":false,"raw_author_name":"Khalid Bashir","raw_affiliation_strings":["Emergency Medicine Department, Hamad Medical Corporation, Doha, Qatar","The College of Medicine QU Health, Qatar University, Doha, Qatar"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Emergency Medicine Department, Hamad Medical Corporation, Doha, Qatar","institution_ids":["https://openalex.org/I49828101"]},{"raw_affiliation_string":"The College of Medicine QU Health, Qatar University, Doha, Qatar","institution_ids":["https://openalex.org/I60342839"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009609448","display_name":"Amr Mohammed Elmoheen","orcid":"https://orcid.org/0000-0002-5079-5353","observed_orcids":["https://orcid.org/0000-0002-5079-5353"]},"institutions":[{"id":"https://openalex.org/I49828101","display_name":"Hamad Medical Corporation","ror":"https://ror.org/02zwb6n98","country_code":"QA","type":"nonprofit","lineage":["https://openalex.org/I49828101"]},{"id":"https://openalex.org/I60342839","display_name":"Qatar University","ror":"https://ror.org/00yhnba62","country_code":"QA","type":"education","lineage":["https://openalex.org/I60342839"]}],"countries":["QA"],"is_corresponding":false,"raw_author_name":"Amr Elmoheen","raw_affiliation_strings":["Emergency Medicine Department, Hamad Medical Corporation, Doha, Qatar","The College of Medicine QU Health, Qatar University, Doha, Qatar"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Emergency Medicine Department, Hamad Medical Corporation, Doha, Qatar","institution_ids":["https://openalex.org/I49828101"]},{"raw_affiliation_string":"The College of Medicine QU Health, Qatar University, Doha, Qatar","institution_ids":["https://openalex.org/I60342839"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003710360","display_name":"Haris Iftikhar","orcid":"https://orcid.org/0000-0002-7091-1243","observed_orcids":["https://orcid.org/0000-0002-7091-1243"]},"institutions":[{"id":"https://openalex.org/I49828101","display_name":"Hamad Medical Corporation","ror":"https://ror.org/02zwb6n98","country_code":"QA","type":"nonprofit","lineage":["https://openalex.org/I49828101"]}],"countries":["QA"],"is_corresponding":false,"raw_author_name":"Haris Iftikhar","raw_affiliation_strings":["Emergency Medicine Department, Hamad Medical Corporation, Doha, Qatar"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Emergency Medicine Department, Hamad Medical Corporation, Doha, Qatar","institution_ids":["https://openalex.org/I49828101"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5080282788","display_name":"Hany A Zaki","orcid":"https://orcid.org/0000-0002-3994-7088","observed_orcids":["https://orcid.org/0000-0002-3994-7088"]},"institutions":[{"id":"https://openalex.org/I49828101","display_name":"Hamad Medical Corporation","ror":"https://ror.org/02zwb6n98","country_code":"QA","type":"nonprofit","lineage":["https://openalex.org/I49828101"]}],"countries":["QA"],"is_corresponding":false,"raw_author_name":"Hany A. Zaki","raw_affiliation_strings":["Emergency Medicine Department, Hamad Medical Corporation, Doha, Qatar"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Emergency Medicine Department, Hamad Medical Corporation, Doha, Qatar","institution_ids":["https://openalex.org/I49828101"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5077482722"],"corresponding_institution_ids":["https://openalex.org/I21376657","https://openalex.org/I4210152471","https://openalex.org/I49828101","https://openalex.org/I60342839"],"apc_list":{"value":2760,"currency":"USD","value_usd":2760},"apc_paid":{"value":2760,"currency":"USD","value_usd":2760},"fwci":0.3521,"has_fulltext":true,"cited_by_count":8,"citation_normalized_percentile":{"value":0.33424583,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":96},"biblio":{"volume":"50","issue":null,"first_page":"101238","last_page":"101238"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10322","display_name":"Respiratory Support and Mechanisms","score":0.9926999807357788,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10322","display_name":"Respiratory Support and Mechanisms","score":0.9926999807357788,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10041","display_name":"COVID-19 Clinical Research Studies","score":0.003800000064074993,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10830","display_name":"Airway Management and Intubation Techniques","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/2703","display_name":"Anesthesiology and Pain Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/high-flow-nasal-cannula","display_name":"high-flow nasal cannula","score":0.9350000023841858},{"id":"https://openalex.org/keywords/covid-19","display_name":"COVID-19 pandemic","score":0.9990000128746033},{"id":"https://openalex.org/keywords/sars-cov-2","display_name":"SARS-CoV-2","score":0.9819999933242798},{"id":"https://openalex.org/keywords/oxygen-therapy","display_name":"oxygen therapy","score":0.5870000123977661},{"id":"https://openalex.org/keywords/mortality","display_name":"mortality","score":0.8109999895095825},{"id":"https://openalex.org/keywords/intubation","display_name":"intubation","score":0.824999988079071},{"id":"https://openalex.org/keywords/rox-index","display_name":"ROX index","score":0.9330000281333923},{"id":"https://openalex.org/keywords/pao2-fio2-ratio","display_name":"PaO2/FiO2 ratio","score":0.9470000267028809},{"id":"https://openalex.org/keywords/spo2-fio2-ratio","display_name":"SpO2/FiO2 ratio","score":0.8560000061988831},{"id":"https://openalex.org/keywords/respiratory-rate","display_name":"respiratory rate","score":0.8690000176429749},{"id":"https://openalex.org/keywords/adult-patients","display_name":"adult patients","score":0.6399999856948853},{"id":"https://openalex.org/keywords/emergency-care","display_name":"emergency care","score":0.781000018119812},{"id":"https://openalex.org/keywords/non-invasive-ventilation","display_name":"non-invasive ventilation","score":0.5450000166893005},{"id":"https://openalex.org/keywords/avoidance-of-mechanical-ventilation","display_name":"mechanical ventilation avoidance","score":0.5059999823570251},{"id":"https://openalex.org/keywords/hypoxemia","display_name":"hypoxemia","score":0.5699999928474426},{"id":"https://openalex.org/keywords/hypercapnia","display_name":"hypercapnia","score":0.4659999907016754}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9049144983291626},{"id":"https://openalex.org/C95190672","wikidata":"https://www.wikidata.org/wiki/Q815382","display_name":"Meta-analysis","level":2,"score":0.6304398775100708},{"id":"https://openalex.org/C3008058167","wikidata":"https://www.wikidata.org/wiki/Q84263196","display_name":"Coronavirus disease 2019 (COVID-19)","level":4,"score":0.5705248117446899},{"id":"https://openalex.org/C2776478404","wikidata":"https://www.wikidata.org/wiki/Q1105187","display_name":"Cochrane Library","level":3,"score":0.5659759044647217},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.501178503036499},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.43117833137512207},{"id":"https://openalex.org/C2780630273","wikidata":"https://www.wikidata.org/wiki/Q1988216","display_name":"Oxygen therapy","level":2,"score":0.42693769931793213},{"id":"https://openalex.org/C2778716859","wikidata":"https://www.wikidata.org/wiki/Q939018","display_name":"Intubation","level":2,"score":0.4184529781341553},{"id":"https://openalex.org/C179755657","wikidata":"https://www.wikidata.org/wiki/Q58702","display_name":"Mortality rate","level":2,"score":0.4137577414512634},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.32824358344078064},{"id":"https://openalex.org/C524204448","wikidata":"https://www.wikidata.org/wiki/Q788926","display_name":"Infectious disease (medical specialty)","level":3,"score":0.2620816230773926},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.21640396118164062}],"mesh":[],"locations_count":7,"locations":[{"id":"doi:10.1016/j.tacc.2023.101238","doi":"https://doi.org/10.1016/j.tacc.2023.101238","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.tacc.2023.101238","pdf_url":null,"source":{"id":"https://openalex.org/S2764716574","display_name":"Trends in Anaesthesia and Critical Care","issn_l":"2210-8440","issn":["2210-8440","2210-8467"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","norway-1","poland-40","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Trends in Anaesthesia and Critical Care","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:10111871","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10111871","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10111871/pdf/main.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Trends in Anaesthesia & Critical Care","raw_type":"Text"},{"id":"pmid:38620122","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38620122","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Trends in anaesthesia & critical care","raw_type":"Journal Article"},{"id":"pmh:oai:figshare.com:article/25117091","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/journal_contribution/High_flow_nasal_oxygen_HFNO_in_the_treatment_of_COVID-19_infection_of_adult_patients_from_An_emergency_perspective_A_systematic_review_and_meta-analysis/25117091","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:qspace.qu.edu.qa:10576/44613","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10576/44613","pdf_url":null,"source":{"id":"https://openalex.org/S4306400014","display_name":"Qatar University QSpace (Qatar University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I60342839","host_organization_name":"Qatar University","host_organization_lineage":["https://openalex.org/I60342839"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article"},{"id":"doi:10.60692/gw15t-ttz36","doi":"https://doi.org/10.60692/gw15t-ttz36","is_oa":true,"landing_page_url":"https://doi.org/10.60692/gw15t-ttz36","pdf_url":null,"source":{"id":"https://openalex.org/S7407051682","display_name":"Greater South Information System","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article-journal"},{"id":"doi:10.60692/jwbyg-k8m30","doi":"https://doi.org/10.60692/jwbyg-k8m30","is_oa":true,"landing_page_url":"https://doi.org/10.60692/jwbyg-k8m30","pdf_url":null,"source":{"id":"https://openalex.org/S7407051682","display_name":"Greater South Information System","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article-journal"}],"best_oa_location":{"id":"doi:10.1016/j.tacc.2023.101238","doi":"https://doi.org/10.1016/j.tacc.2023.101238","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.tacc.2023.101238","pdf_url":null,"source":{"id":"https://openalex.org/S2764716574","display_name":"Trends in Anaesthesia and Critical Care","issn_l":"2210-8440","issn":["2210-8440","2210-8467"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","norway-1","poland-40","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Trends in Anaesthesia and Critical Care","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Systematic Review","id":"https://openalex.org/study-designs/systematic-review"},{"display_name":"Meta-Analysis","id":"https://openalex.org/study-designs/meta-analysis"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320334468","display_name":"Qatar National Library","ror":"https://ror.org/02jv93662"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4366262986.pdf","grobid_xml":"https://content.openalex.org/works/W4366262986.grobid-xml"},"referenced_works_count":38,"referenced_works":["https://openalex.org/W1979112585","https://openalex.org/W2115412499","https://openalex.org/W2183974602","https://openalex.org/W2313296099","https://openalex.org/W2313356342","https://openalex.org/W2417078906","https://openalex.org/W2739506637","https://openalex.org/W2771181037","https://openalex.org/W2811464749","https://openalex.org/W2947792277","https://openalex.org/W2980667248","https://openalex.org/W3013598912","https://openalex.org/W3013671288","https://openalex.org/W3013907926","https://openalex.org/W3014213099","https://openalex.org/W3034033410","https://openalex.org/W3045097086","https://openalex.org/W3046804999","https://openalex.org/W3047272908","https://openalex.org/W3048002501","https://openalex.org/W3089710067","https://openalex.org/W3111429010","https://openalex.org/W3111500722","https://openalex.org/W3115768346","https://openalex.org/W3127627549","https://openalex.org/W3132359270","https://openalex.org/W3137551872","https://openalex.org/W3146846023","https://openalex.org/W3153082872","https://openalex.org/W3159486339","https://openalex.org/W3198104781","https://openalex.org/W3198531451","https://openalex.org/W3209377574","https://openalex.org/W4206435828","https://openalex.org/W4224862339","https://openalex.org/W4280537699","https://openalex.org/W6784509117","https://openalex.org/W6838906051"],"related_works":["https://openalex.org/W3165322336","https://openalex.org/W3205620304","https://openalex.org/W7148551199","https://openalex.org/W4200150725","https://openalex.org/W4224862339","https://openalex.org/W4312824215","https://openalex.org/W4214687464","https://openalex.org/W4205779747","https://openalex.org/W4406787870","https://openalex.org/W4416636007"],"abstract_inverted_index":{"Coronavirus":[0],"disease":[1,7,19,35],"2019":[2,141],"(COVID-19)":[3],"is":[4,263],"an":[5,322],"infectious":[6],"caused":[8],"by":[9,348],"SARS-CoV-2,":[10],"which":[11,156],"was":[12,107,126,173,194,198,272],"first":[13],"discovered":[14],"in":[15,31,148,204,274,308,325],"Wuhan,":[16],"China.":[17],"The":[18,34,144],"has":[20,69,224,317],"grown":[21],"into":[22],"a":[23,201,251],"global":[24],"pandemic":[25],"causing":[26],"mild":[27],"to":[28,72,75,92,138,142,320],"moderate":[29],"symptoms":[30],"most":[32],"people.":[33],"can":[36,333],"also":[37],"exhibit":[38],"serious":[39],"illnesses,":[40],"especially":[41],"for":[42,102,336],"patients":[43,312,338],"with":[44,200,247,265,340],"other":[45],"chronic":[46,53],"diseases":[47],"such":[48,59],"as":[49,131],"cardiovascular":[50],"diseases,":[51],"diabetes,":[52],"respiratory":[54,254],"disease,":[55],"or":[56,304],"cancer.":[57],"In":[58],"cases":[60],"of":[61,81,88,96,155,306],"severe":[62],"illness,":[63],"high":[64],"flow":[65],"nasal":[66],"oxygen":[67],"(HFNO)":[68],"been":[70,318],"used":[71],"provide":[73],"oxygenation":[74],"COVID-19":[76,139,310,337],"patients.":[77],"However,":[78,315],"the":[79,86,94,97,129,135,160,192,278,297,302],"efficiency":[80],"HFNO":[82,170,176,197,248,266,279,307,316,332],"remains":[83,313],"uncertain,":[84],"prompting":[85],"conduction":[87],"this":[89,149],"systematic":[90,150],"review":[91,151],"evaluate":[93],"effectiveness":[95],"therapy.":[98],"A":[99],"thorough":[100],"search":[101,130,145],"relevant":[103],"and":[104,120,163,184,206,214,237,281,328,343],"original":[105],"articles":[106,136],"carried":[108,346],"out":[109,347],"on":[110,296],"five":[111],"electronic":[112],"databases,":[113],"including":[114],"ScienceDirect,":[115],"PubMed,":[116],"Cochrane":[117],"Library,":[118],"Embase,":[119],"Google":[121],"Scholar.":[122],"No":[123,268],"time":[124],"limitation":[125],"placed":[127],"during":[128],"it":[132],"included":[133],"all":[134],"related":[137],"from":[140,299],"2022.":[143],"strategy":[146],"utilized":[147],"yielded":[152],"504":[153],"articles,":[154],"only":[157],"10":[158],"met":[159],"eligibility":[161],"criteria":[162],"were":[164],"included.":[165],"Our":[166,221],"meta-analysis":[167],"reveals":[168],"that":[169,226],"success":[171,280,303],"rate":[172,255],"higher":[174],"than":[175],"failure":[177,282,305],"rates":[178,208],"(0.52":[179],"(95%":[180,186,210,216],"CI;":[181,187,211,217],"0.47,":[182],"0.56)":[183],"0.48":[185],"0.44,":[188],"0.53),":[189],"respectively),":[190],"however,":[191],"difference":[193,271],"statistically":[195,269],"insignificant.":[196],"associated":[199,246,264],"significant":[202,270],"decrease":[203],"mortality":[205,327],"intubation":[207,329],"(0.28":[209],"0.19,":[212],"0.39)":[213],"0.28":[215],"0.18,":[218],"0.41),":[219],"respectively).":[220,294],"statistical":[222],"analysis":[223],"shown":[225,319],"significantly":[227,252],"lower":[228,253],"ROX":[229],"index":[230],"(5.07":[231],"\u00b1":[232,240,258,285,289],"1.66,":[233],"p":[234,242,260,291],"=":[235,243,261,292],"0.028)":[236],"PaO2/FiO2":[238],"(100":[239],"27.51,":[241],"0.031)":[244],"are":[245],"failure,":[249],"while":[250],"(RR)":[256],"(23.17":[257],"4.167,":[259],"0.006)":[262],"success.":[267],"observed":[273],"SpO2/FiO2":[275],"ratio":[276],"between":[277],"groups":[283],"(154.23":[284],"42.74":[286],"vs.":[287],"124.025":[288],"28.50,":[290],"0.62,":[293],"Based":[295],"results":[298],"our":[300],"meta-analysis,":[301],"treating":[309],"adult":[311],"uncertain.":[314],"be":[321,334,345],"effective":[323],"treatment":[324],"reducing":[326],"rates.":[330],"Therefore,":[331],"recommended":[335],"but":[339],"close":[341],"monitoring":[342],"should":[344],"experienced":[349],"healthcare":[350],"workers.":[351]},"counts_by_year":[{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":2}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2023-04-20T00:00:00"}