{"id":"https://openalex.org/W4366201625","doi":"https://doi.org/10.53350/pjmhs2023172623","title":"Possible Association of Female-Pattern Hair Loss with Alteration in Serum 25-Hydroxyvitamin D Levels","display_name":"Possible Association of Female-Pattern Hair Loss with Alteration in Serum 25-Hydroxyvitamin D Levels","publication_year":2023,"publication_date":"2023-03-26","ids":{"openalex":"https://openalex.org/W4366201625","doi":"https://doi.org/10.53350/pjmhs2023172623"},"language":"en","primary_location":{"id":"doi:10.53350/pjmhs2023172623","doi":"https://doi.org/10.53350/pjmhs2023172623","is_oa":true,"landing_page_url":"http://dx.doi.org/10.53350/pjmhs2023172623","pdf_url":"https://pjmhsonline.com/index.php/pjmhs/article/download/4399/4349","source":{"id":"https://openalex.org/S4306521916","display_name":"Pakistan Journal of Medical and Health Sciences","issn_l":"1996-7195","issn":["1996-7195","2957-899X"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":["poland-20"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pakistan Journal of Medical and Health Sciences","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://pjmhsonline.com/index.php/pjmhs/article/download/4399/4349","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5074908401","display_name":"Raef Hailat","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210134505","display_name":"Primary Health Care","ror":"https://ror.org/03djtgh02","country_code":"QA","type":"government","lineage":["https://openalex.org/I4210134505"]}],"countries":["QA"],"is_corresponding":false,"raw_author_name":"Raef Hailat","raw_affiliation_strings":["MD Primary Health Care Corporation , Qatar","MD Primary Health Care Corporation, Qatar"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"MD Primary Health Care Corporation , Qatar","institution_ids":["https://openalex.org/I4210134505"]},{"raw_affiliation_string":"MD Primary Health Care Corporation, Qatar","institution_ids":["https://openalex.org/I4210134505"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Hira Mughal","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4388446382","display_name":"Bilawal Medical College","ror":"https://ror.org/04b786w92","country_code":null,"type":"education","lineage":["https://openalex.org/I4388446382"]}],"countries":[],"is_corresponding":false,"raw_author_name":"Hira Mughal","raw_affiliation_strings":["Senior Registrar, Department of Dermatology Bilawal Medical College for Boys , LUMHS Jamshoro","Senior Registrar, Department of Dermatology Bilawal Medical College for Boys, LUMHS Jamshoro"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Senior Registrar, Department of Dermatology Bilawal Medical College for Boys , LUMHS Jamshoro","institution_ids":["https://openalex.org/I4388446382"]},{"raw_affiliation_string":"Senior Registrar, Department of Dermatology Bilawal Medical College for Boys, LUMHS Jamshoro","institution_ids":["https://openalex.org/I4388446382"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008096559","display_name":"Tooba Malik","orcid":"https://orcid.org/0000-0002-2144-2815","observed_orcids":["https://orcid.org/0000-0002-2144-2815"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Tooba Malik","raw_affiliation_strings":["Classified Dermatologist PNS Rahat Hospital Karachi / Assistant Professor of Dermatology BUM&DC , Karachi","Classified Dermatologist PNS Rahat Hospital Karachi/ Assistant Professor of Dermatology BUM&DC, Karachi"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Classified Dermatologist PNS Rahat Hospital Karachi / Assistant Professor of Dermatology BUM&DC , Karachi","institution_ids":[]},{"raw_affiliation_string":"Classified Dermatologist PNS Rahat Hospital Karachi/ Assistant Professor of Dermatology BUM&DC, Karachi","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081262349","display_name":"Afshan Sagheer","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Afshan Sagheer","raw_affiliation_strings":["Assistant Physician , Department of Dermatology , Federal Govt Polyclinic Hospital (PGMI) , Islamabad","Assistant Physician, Department of Dermatology, Federal Govt Polyclinic Hospital (PGMI), Islamabad"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Assistant Physician , Department of Dermatology , Federal Govt Polyclinic Hospital (PGMI) , Islamabad","institution_ids":[]},{"raw_affiliation_string":"Assistant Physician, Department of Dermatology, Federal Govt Polyclinic Hospital (PGMI), Islamabad","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113244806","display_name":"Asma Javed","orcid":"https://orcid.org/0009-0001-3181-6016","observed_orcids":["https://orcid.org/0009-0001-3181-6016"]},"institutions":[{"id":"https://openalex.org/I1318157472","display_name":"Liaquat University of Medical & Health Sciences","ror":"https://ror.org/015jxh185","country_code":"PK","type":"education","lineage":["https://openalex.org/I1318157472"]},{"id":"https://openalex.org/I152236710","display_name":"Foundation University Islamabad","ror":"https://ror.org/0130a6s10","country_code":"PK","type":"education","lineage":["https://openalex.org/I152236710"]}],"countries":["PK"],"is_corresponding":false,"raw_author_name":"Asma Javed","raw_affiliation_strings":["Assistant Professor of Dermatology , Foundation University Islamabad , Fauji Foundation Hospital ,","Senior Registrar, Liaquat University of Medical and Health Science (LUMHS) , Jamshoro","Assistant Professor of Dermatology, Foundation University Islamabad, Fauji Foundation Hospital,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Assistant Professor of Dermatology , Foundation University Islamabad , Fauji Foundation Hospital ,","institution_ids":["https://openalex.org/I152236710"]},{"raw_affiliation_string":"Senior Registrar, Liaquat University of Medical and Health Science (LUMHS) , Jamshoro","institution_ids":["https://openalex.org/I1318157472"]},{"raw_affiliation_string":"Assistant Professor of Dermatology, Foundation University Islamabad, Fauji Foundation Hospital,","institution_ids":["https://openalex.org/I152236710"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5035738143","display_name":"Quratulain Memon","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1318157472","display_name":"Liaquat University of Medical & Health Sciences","ror":"https://ror.org/015jxh185","country_code":"PK","type":"education","lineage":["https://openalex.org/I1318157472"]}],"countries":["PK"],"is_corresponding":false,"raw_author_name":"Quratulain Memon","raw_affiliation_strings":["Senior Registrar, Liaquat University of Medical and Health Science (LUMHS), Jamshoro"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Senior Registrar, Liaquat University of Medical and Health Science (LUMHS), Jamshoro","institution_ids":["https://openalex.org/I1318157472"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5081262349"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.7854,"has_fulltext":true,"cited_by_count":3,"citation_normalized_percentile":{"value":0.70527682,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"17","issue":"2","first_page":"623","last_page":"625"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11167","display_name":"Hair Growth and Disorders","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2748","display_name":"Urology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11167","display_name":"Hair Growth and Disorders","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2748","display_name":"Urology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10277","display_name":"Vitamin D Research Studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10390","display_name":"Ovarian function and disorders","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/female-pattern-hair-loss","display_name":"female pattern hair loss","score":0.9940000176429749},{"id":"https://openalex.org/keywords/25-hydroxyvitamin-d","display_name":"25-hydroxyvitamin D","score":0.906000018119812},{"id":"https://openalex.org/keywords/vitamin-d-deficiency","display_name":"vitamin D deficiency","score":0.9810000061988831},{"id":"https://openalex.org/keywords/diffuse-hair-loss","display_name":"diffuse hair loss","score":0.7269999980926514},{"id":"https://openalex.org/keywords/vitamin-d-status","display_name":"vitamin D status","score":0.3319999873638153},{"id":"https://openalex.org/keywords/women-s-health","display_name":"women's health","score":0.6729999780654907},{"id":"https://openalex.org/keywords/seasonal-variation-in-vitamin-d","display_name":"seasonal variation in vitamin D","score":0.6140000224113464},{"id":"https://openalex.org/keywords/vitamin-d-toxicity","display_name":"vitamin D toxicity","score":0.5789999961853027},{"id":"https://openalex.org/keywords/vitamin-d-supplementation","display_name":"vitamin D supplementation","score":0.4399999976158142}],"concepts":[{"id":"https://openalex.org/C2776360568","wikidata":"https://www.wikidata.org/wiki/Q2697787","display_name":"Hair loss","level":2,"score":0.8203933238983154},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7088764905929565},{"id":"https://openalex.org/C124490489","wikidata":"https://www.wikidata.org/wiki/Q7936963","display_name":"Vitamin D and neurology","level":2,"score":0.5088491439819336},{"id":"https://openalex.org/C2781179581","wikidata":"https://www.wikidata.org/wiki/Q2857712","display_name":"Family history","level":2,"score":0.5055270195007324},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3949345350265503},{"id":"https://openalex.org/C42407357","wikidata":"https://www.wikidata.org/wiki/Q521","display_name":"Physiology","level":1,"score":0.37198394536972046},{"id":"https://openalex.org/C16005928","wikidata":"https://www.wikidata.org/wiki/Q171171","display_name":"Dermatology","level":1,"score":0.3588781952857971},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.33537209033966064}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.53350/pjmhs2023172623","doi":"https://doi.org/10.53350/pjmhs2023172623","is_oa":true,"landing_page_url":"http://dx.doi.org/10.53350/pjmhs2023172623","pdf_url":"https://pjmhsonline.com/index.php/pjmhs/article/download/4399/4349","source":{"id":"https://openalex.org/S4306521916","display_name":"Pakistan Journal of Medical and Health Sciences","issn_l":"1996-7195","issn":["1996-7195","2957-899X"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":["poland-20"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pakistan Journal of Medical and Health Sciences","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.53350/pjmhs2023172623","doi":"https://doi.org/10.53350/pjmhs2023172623","is_oa":true,"landing_page_url":"http://dx.doi.org/10.53350/pjmhs2023172623","pdf_url":"https://pjmhsonline.com/index.php/pjmhs/article/download/4399/4349","source":{"id":"https://openalex.org/S4306521916","display_name":"Pakistan Journal of Medical and Health Sciences","issn_l":"1996-7195","issn":["1996-7195","2957-899X"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":["poland-20"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pakistan Journal of Medical and Health Sciences","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.6899999976158142}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4366201625.pdf","grobid_xml":"https://content.openalex.org/works/W4366201625.grobid-xml"},"referenced_works_count":26,"referenced_works":["https://openalex.org/W115193909","https://openalex.org/W1974280043","https://openalex.org/W1987491399","https://openalex.org/W2299802183","https://openalex.org/W2329165653","https://openalex.org/W2345440529","https://openalex.org/W2514841356","https://openalex.org/W2518862288","https://openalex.org/W2521185045","https://openalex.org/W2568330843","https://openalex.org/W2609069380","https://openalex.org/W2735655123","https://openalex.org/W2764339060","https://openalex.org/W2771597004","https://openalex.org/W2772492634","https://openalex.org/W2775684989","https://openalex.org/W2782248798","https://openalex.org/W2796637346","https://openalex.org/W2806560778","https://openalex.org/W2884636588","https://openalex.org/W2901646890","https://openalex.org/W2940129544","https://openalex.org/W3015559713","https://openalex.org/W3109269000","https://openalex.org/W4312765563","https://openalex.org/W4313517599"],"related_works":["https://openalex.org/W4248956811","https://openalex.org/W3177294835","https://openalex.org/W4210861261","https://openalex.org/W2543427153","https://openalex.org/W2284519374","https://openalex.org/W2324183690","https://openalex.org/W2902825968","https://openalex.org/W2003686112","https://openalex.org/W1961711772","https://openalex.org/W1978243905"],"abstract_inverted_index":{"Background":[0],"and":[1,62,84,100,121,133,140,195,237,275,282,306,315,323],"Aim:":[2],"Most":[3],"women":[4,340],"who":[5],"experience":[6],"diffuse":[7],"hair":[8,13,40,50,162,331,349],"loss":[9,14,51,163,332],"suffer":[10],"from":[11,86,138],"female-pattern":[12,49],"(FPHL).":[15],"Several":[16],"mechanisms":[17],"other":[18,39],"than":[19,256],"androgen":[20],"have":[21,345],"been":[22,36],"suggested":[23],"as":[24,110,145,220,317,319],"contributing":[25],"to":[26,46,89,177],"the":[27,48,118,159,296,356,379],"process.":[28],"Serum":[29,242,391],"25-hydroxy":[30,392],"vitamin":[31,265,290,342,393],"D":[32,59,244,266,291,343,368,394],"[25-(OH)":[33],"D]":[34],"has":[35],"associated":[37],"with":[38,54,96,182,274,341],"disorders.":[41],"The":[42,208,263,288,326],"present":[43,327],"study":[44,66,328],"aimed":[45],"assess":[47],"possible":[52],"association":[53],"variation":[55],"in":[56,82,224,229,234,246,257,355,365,378],"serum":[57,366],"25-hydroxyvitamin":[58],"levels.":[60],"Patients":[61,142],"Methods:":[63],"This":[64],"case-control":[65],"was":[67,115,202,212],"conducted":[68],"on":[69,154],"72":[70,105],"FPHL":[71,128,152,247],"diagnosed":[72],"female":[73],"patients":[74,218,248,273],"attending":[75],"dermatology":[76],"department":[77],"of":[78,158,161,172,217,348,381],"Tertiary":[79],"Care":[80],"Hospitals":[81],"Jamshoro":[83],"Karachi":[85],"November":[87],"2021":[88],"October":[90],"2022.":[91],"Females":[92,181],"aged":[93],"18-40":[94],"years":[95],"skin":[97],"prototypes":[98],"III":[99,151],"IV":[101],"were":[102,108,136,143,175,187,219,249],"enrolled.":[103],"About":[104],"healthy":[106],"females":[107],"considered":[109],"control":[111],"group.":[112],"Study":[113],"protocol":[114],"approved":[116],"by":[117,361],"institutional":[119],"research":[120],"ethical":[122],"committee.":[123],"Careful":[124],"history,":[125,130,132],"socioeconomic":[126],"status,":[127],"family":[129,277],"menstrual":[131],"drug":[134],"intake":[135],"recorded":[137],"cases":[139],"control.":[141],"classified":[144],"having":[146],"stage":[147],"I,":[148],"II,":[149],"or":[150,372],"based":[153],"a":[155,170,376],"clinical":[156],"evaluation":[157],"pattern":[160],"using":[164],"Ludwig's":[165,298],"scale.":[166],"25-OHD":[167,183],"levels":[168,184,245],"over":[169],"period":[171],"4":[173],"months":[174],"measured":[176],"minimize":[178],"seasonal":[179],"bias.":[180],"<20":[185],"ng/ml":[186],"deficient,":[188],"insufficient":[189],"21\u201329":[190],"ng/ml,":[191,194,286,310],"sufficient":[192],">30":[193],"intoxication":[196],">150":[197],"ng/ml.":[198],"SPSS":[199],"version":[200],"26":[201],"used":[203],"for":[204],"data":[205],"analysis.":[206],"Results:":[207],"overall":[209],"mean":[210,264,289],"age":[211,337,357],"28.6\u00b12.4":[213],"years.":[214,241],"Age-wise":[215],"distribution":[216],"follows:":[221],"9":[222],"(12.5%)":[223],"18-25":[225],"years,":[226,231,236],"24":[227],"(33.3%)":[228],"26-30":[230],"21":[232],"(29.2%)":[233],"31-35":[235],"18":[238],"(25%)":[239],"36-40":[240],"25-(OH)":[243,367],"significantly":[250,271,294,334],"lower":[251],"(15.4":[252],"\u00b1":[253,260,280,284,301,304,308],"8.25":[254],"ng/ml)":[255],"controls":[258],"(46.42":[259],"19.92":[261],"ng/ml).":[262],"level":[267,292],"did":[268],"not":[269],"differ":[270],"between":[272,295,312,320],"without":[276],"history":[278],"(14.46":[279],"8.62":[281],"13.9":[283],"8.24":[285],"respectively.":[287],"differed":[293],"three":[297],"degrees":[299,313,321],"(13.15":[300],"8.49,":[302],"14.23":[303],"6.74,":[305],"24.9":[307],"6.42":[309],"respectively):":[311],"I":[314],"III,":[316],"well":[318],"II":[322],"III.":[324],"Conclusion:":[325],"showed":[329],"that":[330],"varied":[333],"across":[335],"all":[336],"groups.":[338],"Premenopausal":[339],"deficiency":[344],"higher":[346],"rates":[347],"loss,":[350],"which":[351],"is":[352],"most":[353],"profound":[354],"groups":[358],"26-30,":[359],"followed":[360],"25-30.":[362],"Furthermore,":[363],"changes":[364],"levels,":[369],"whether":[370],"deficient":[371],"sufficient,":[373],"may":[374],"play":[375],"role":[377],"etiology":[380],"FPHL.":[382],"Keywords:":[383],"Female":[384],"Pattern":[385],"Hair":[386],"Loss":[387],"(FPHL),":[388],"Vitamin":[389],"D,":[390]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1}],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2025-10-10T00:00:00"}