{"id":"https://openalex.org/W4366133647","doi":"https://doi.org/10.1016/j.foodres.2023.112849","title":"Whey protein isolate attenuates depression-like behavior developed in a mouse model of breast tumor","display_name":"Whey protein isolate attenuates depression-like behavior developed in a mouse model of breast tumor","publication_year":2023,"publication_date":"2023-04-18","ids":{"openalex":"https://openalex.org/W4366133647","doi":"https://doi.org/10.1016/j.foodres.2023.112849","pmid":"https://pubmed.ncbi.nlm.nih.gov/37254425"},"language":"en","primary_location":{"id":"doi:10.1016/j.foodres.2023.112849","doi":"https://doi.org/10.1016/j.foodres.2023.112849","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.foodres.2023.112849","pdf_url":null,"source":{"id":"https://openalex.org/S38919146","display_name":"Food Research International","issn_l":"0963-9969","issn":["0963-9969","1873-7145"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-c","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Food Research International","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5024571458","display_name":"Shufang Xia","orcid":"https://orcid.org/0000-0002-8977-4760","observed_orcids":["https://orcid.org/0000-0002-8977-4760"]},"institutions":[{"id":"https://openalex.org/I111599522","display_name":"Jiangnan University","ror":"https://ror.org/04mkzax54","country_code":"CN","type":"education","lineage":["https://openalex.org/I111599522"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Shufang Xia","raw_affiliation_strings":["Wuxi School of Medicine, Jiangnan University, Wuxi, Jiangsu, China. Electronic address: xiashufang@jiangnan.edu.cn","Wuxi School of Medicine, Jiangnan University, Wuxi, Jiangsu, China"],"raw_orcid":"https://orcid.org/0000-0002-8977-4760","affiliations":[{"raw_affiliation_string":"Wuxi School of Medicine, Jiangnan University, Wuxi, Jiangsu, China. Electronic address: xiashufang@jiangnan.edu.cn","institution_ids":["https://openalex.org/I111599522"]},{"raw_affiliation_string":"Wuxi School of Medicine, Jiangnan University, Wuxi, Jiangsu, China","institution_ids":["https://openalex.org/I111599522"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012788065","display_name":"Gusonghan Maitiniyazi","orcid":"https://orcid.org/0000-0002-5436-8156","observed_orcids":["https://orcid.org/0000-0002-5436-8156"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Gusonghan Maitiniyazi","raw_affiliation_strings":["Department of Nursing, College of Xinjiang Uyghur Medicine, Hetian, Xinjiang, China"],"raw_orcid":"https://orcid.org/0000-0002-5436-8156","affiliations":[{"raw_affiliation_string":"Department of Nursing, College of Xinjiang Uyghur Medicine, Hetian, Xinjiang, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043321507","display_name":"Yuan Liu","orcid":"https://orcid.org/0000-0003-2866-5138","observed_orcids":["https://orcid.org/0000-0003-2866-5138"]},"institutions":[{"id":"https://openalex.org/I111599522","display_name":"Jiangnan University","ror":"https://ror.org/04mkzax54","country_code":"CN","type":"education","lineage":["https://openalex.org/I111599522"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yuan Liu","raw_affiliation_strings":["Wuxi School of Medicine, Jiangnan University, Wuxi, Jiangsu, China"],"raw_orcid":"https://orcid.org/0000-0003-2866-5138","affiliations":[{"raw_affiliation_string":"Wuxi School of Medicine, Jiangnan University, Wuxi, Jiangsu, China","institution_ids":["https://openalex.org/I111599522"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100454833","display_name":"Yue Chen","orcid":"https://orcid.org/0000-0003-1298-7415","observed_orcids":["https://orcid.org/0000-0003-1298-7415"]},"institutions":[{"id":"https://openalex.org/I111599522","display_name":"Jiangnan University","ror":"https://ror.org/04mkzax54","country_code":"CN","type":"education","lineage":["https://openalex.org/I111599522"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yue Chen","raw_affiliation_strings":["Wuxi School of Medicine, Jiangnan University, Wuxi, Jiangsu, China"],"raw_orcid":"https://orcid.org/0000-0003-1298-7415","affiliations":[{"raw_affiliation_string":"Wuxi School of Medicine, Jiangnan University, Wuxi, Jiangsu, China","institution_ids":["https://openalex.org/I111599522"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103039177","display_name":"Mengting Guo","orcid":"https://orcid.org/0000-0001-8317-5823","observed_orcids":["https://orcid.org/0000-0001-8317-5823"]},"institutions":[{"id":"https://openalex.org/I4210127460","display_name":"Ningxia Medical University","ror":"https://ror.org/02h8a1848","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210127460"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Mengting Guo","raw_affiliation_strings":["College of Science, Ningxia Medical University, Yinchuan, Ningxia, China"],"raw_orcid":"https://orcid.org/0000-0001-8317-5823","affiliations":[{"raw_affiliation_string":"College of Science, Ningxia Medical University, Yinchuan, Ningxia, China","institution_ids":["https://openalex.org/I4210127460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101972061","display_name":"Jianyun He","orcid":"https://orcid.org/0000-0003-3548-1054","observed_orcids":["https://orcid.org/0000-0003-3548-1054"]},"institutions":[{"id":"https://openalex.org/I111599522","display_name":"Jiangnan University","ror":"https://ror.org/04mkzax54","country_code":"CN","type":"education","lineage":["https://openalex.org/I111599522"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jianyun He","raw_affiliation_strings":["Wuxi School of Medicine, Jiangnan University, Wuxi, Jiangsu, China"],"raw_orcid":"https://orcid.org/0000-0003-3548-1054","affiliations":[{"raw_affiliation_string":"Wuxi School of Medicine, Jiangnan University, Wuxi, Jiangsu, China","institution_ids":["https://openalex.org/I111599522"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5117233249","display_name":"Wei Tao","orcid":"https://orcid.org/0000-0001-7549-9019","observed_orcids":["https://orcid.org/0000-0001-7549-9019"]},"institutions":[{"id":"https://openalex.org/I111599522","display_name":"Jiangnan University","ror":"https://ror.org/04mkzax54","country_code":"CN","type":"education","lineage":["https://openalex.org/I111599522"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wei Tao","raw_affiliation_strings":["Wuxi School of Medicine, Jiangnan University, Wuxi, Jiangsu, China"],"raw_orcid":"https://orcid.org/0000-0001-7549-9019","affiliations":[{"raw_affiliation_string":"Wuxi School of Medicine, Jiangnan University, Wuxi, Jiangsu, China","institution_ids":["https://openalex.org/I111599522"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100746583","display_name":"Ziyuan Li","orcid":"https://orcid.org/0000-0002-8972-5352","observed_orcids":["https://orcid.org/0000-0002-8972-5352"]},"institutions":[{"id":"https://openalex.org/I111599522","display_name":"Jiangnan University","ror":"https://ror.org/04mkzax54","country_code":"CN","type":"education","lineage":["https://openalex.org/I111599522"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ziyuan Li","raw_affiliation_strings":["Wuxi School of Medicine, Jiangnan University, Wuxi, Jiangsu, China"],"raw_orcid":"https://orcid.org/0000-0002-8972-5352","affiliations":[{"raw_affiliation_string":"Wuxi School of Medicine, Jiangnan University, Wuxi, Jiangsu, China","institution_ids":["https://openalex.org/I111599522"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5024571458"],"corresponding_institution_ids":["https://openalex.org/I111599522"],"apc_list":{"value":4030,"currency":"USD","value_usd":4030},"apc_paid":null,"fwci":2.0998,"has_fulltext":false,"cited_by_count":26,"citation_normalized_percentile":{"value":0.85472155,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":99},"biblio":{"volume":"169","issue":null,"first_page":"112849","last_page":"112849"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11337","display_name":"Tryptophan and brain disorders","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2803","display_name":"Biological Psychiatry"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11337","display_name":"Tryptophan and brain disorders","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2803","display_name":"Biological Psychiatry"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11071","display_name":"Treatment of Major Depression","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/whey-protein-isolate","display_name":"whey protein isolate","score":1.0},{"id":"https://openalex.org/keywords/depression-like-behavior","display_name":"depression-like behavior","score":0.8149999976158142},{"id":"https://openalex.org/keywords/breast-cancer","display_name":"breast cancer","score":0.6610000133514404},{"id":"https://openalex.org/keywords/4t1-mammary-carcinoma","display_name":"4T1 mammary carcinoma","score":0.9430000185966492},{"id":"https://openalex.org/keywords/tryptophan-metabolism","display_name":"tryptophan metabolism","score":0.9829999804496765},{"id":"https://openalex.org/keywords/serotonin","display_name":"serotonin","score":0.6850000023841858},{"id":"https://openalex.org/keywords/gut-microbiota","display_name":"gut microbiota","score":0.7990000247955322},{"id":"https://openalex.org/keywords/kynurenine-pathway","display_name":"kynurenine pathway","score":0.8679999709129333},{"id":"https://openalex.org/keywords/serotonin-transporter","display_name":"serotonin transporter","score":0.8209999799728394},{"id":"https://openalex.org/keywords/indoleamine-2-3-dioxygenase","display_name":"indoleamine 2,3-dioxygenase","score":0.9959999918937683},{"id":"https://openalex.org/keywords/hippocampus","display_name":"hippocampus","score":0.6290000081062317},{"id":"https://openalex.org/keywords/depression-in-cancer-patients","display_name":"cancer-related depression","score":0.8190000057220459},{"id":"https://openalex.org/keywords/antidepressant-effects","display_name":"antidepressant effects","score":0.7839999794960022}],"concepts":[{"id":"https://openalex.org/C2779085643","wikidata":"https://www.wikidata.org/wiki/Q7096029","display_name":"Open field","level":2,"score":0.5820589065551758},{"id":"https://openalex.org/C539455810","wikidata":"https://www.wikidata.org/wiki/Q739734","display_name":"Gut flora","level":2,"score":0.5686436891555786},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5159593224525452},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5068994164466858},{"id":"https://openalex.org/C2775900134","wikidata":"https://www.wikidata.org/wiki/Q424430","display_name":"Whey protein isolate","level":3,"score":0.4877813458442688},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4611819386482239},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3688775897026062},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3052932620048523},{"id":"https://openalex.org/C2777897731","wikidata":"https://www.wikidata.org/wiki/Q424430","display_name":"Whey protein","level":2,"score":0.19421043992042542},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.1809805929660797}],"mesh":[{"descriptor_ui":"D000067816","descriptor_name":"Whey Proteins","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003863","descriptor_name":"Depression","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":true},{"descriptor_ui":"D003863","descriptor_name":"Depression","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006916","descriptor_name":"5-Hydroxytryptophan","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007737","descriptor_name":"Kynurenine","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012701","descriptor_name":"Serotonin","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014364","descriptor_name":"Tryptophan","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.foodres.2023.112849","doi":"https://doi.org/10.1016/j.foodres.2023.112849","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.foodres.2023.112849","pdf_url":null,"source":{"id":"https://openalex.org/S38919146","display_name":"Food Research International","issn_l":"0963-9969","issn":["0963-9969","1873-7145"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-c","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Food Research International","raw_type":"journal-article"},{"id":"pmid:37254425","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37254425","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Food research international (Ottawa, Ont.)","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9940000176429749,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1298635192","display_name":null,"funder_award_id":"2017M620191","funder_id":"https://openalex.org/F4320321543","funder_display_name":"China Postdoctoral Science Foundation"},{"id":"https://openalex.org/G5774542746","display_name":null,"funder_award_id":"1701099B","funder_id":"https://openalex.org/F4320335473","funder_display_name":"Postdoctoral Science Foundation of Jiangsu Province"},{"id":"https://openalex.org/G8349605836","display_name":null,"funder_award_id":"81703222","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320321543","display_name":"China Postdoctoral Science Foundation","ror":"https://ror.org/0426zh255"},{"id":"https://openalex.org/F4320326180","display_name":"Jiangsu Postdoctoral Research Foundation","ror":null},{"id":"https://openalex.org/F4320335473","display_name":"Postdoctoral Science Foundation of Jiangsu Province","ror":null}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":51,"referenced_works":["https://openalex.org/W936804720","https://openalex.org/W1951255236","https://openalex.org/W1972237932","https://openalex.org/W1977804070","https://openalex.org/W2000058430","https://openalex.org/W2011522805","https://openalex.org/W2056398440","https://openalex.org/W2064855192","https://openalex.org/W2107457791","https://openalex.org/W2134247733","https://openalex.org/W2138144859","https://openalex.org/W2187173798","https://openalex.org/W2325284965","https://openalex.org/W2337277326","https://openalex.org/W2553511812","https://openalex.org/W2590245531","https://openalex.org/W2695471189","https://openalex.org/W2766569434","https://openalex.org/W2793344219","https://openalex.org/W2807728333","https://openalex.org/W2807729355","https://openalex.org/W2905367379","https://openalex.org/W2911817614","https://openalex.org/W2917230209","https://openalex.org/W2935972832","https://openalex.org/W2945858280","https://openalex.org/W2948144072","https://openalex.org/W2955693266","https://openalex.org/W3008564122","https://openalex.org/W3012313023","https://openalex.org/W3047073943","https://openalex.org/W3092306005","https://openalex.org/W3093719193","https://openalex.org/W3111686686","https://openalex.org/W3121283682","https://openalex.org/W3128646645","https://openalex.org/W3157629070","https://openalex.org/W3173868212","https://openalex.org/W3180636651","https://openalex.org/W3197099864","https://openalex.org/W4205598291","https://openalex.org/W4205915757","https://openalex.org/W4220662863","https://openalex.org/W4220866692","https://openalex.org/W4225152036","https://openalex.org/W4288051145","https://openalex.org/W4297826660","https://openalex.org/W4308498690","https://openalex.org/W6679817727","https://openalex.org/W6686699945","https://openalex.org/W6790598159"],"related_works":["https://openalex.org/W4415080579","https://openalex.org/W4407813037","https://openalex.org/W4283789776","https://openalex.org/W4412602767","https://openalex.org/W2899509681","https://openalex.org/W4402654921","https://openalex.org/W3044453503","https://openalex.org/W4402822353","https://openalex.org/W2948144072","https://openalex.org/W4410213546"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":7},{"year":2025,"cited_by_count":14},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":2}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2023-04-19T00:00:00"}