{"id":"https://openalex.org/W4366133286","doi":"https://doi.org/10.1016/j.clim.2023.109330","title":"Serum proteome and metabolome uncover novel biomarkers for the assessment of disease activity and diagnosing of systemic lupus erythematosus","display_name":"Serum proteome and metabolome uncover novel biomarkers for the assessment of disease activity and diagnosing of systemic lupus erythematosus","publication_year":2023,"publication_date":"2023-04-17","ids":{"openalex":"https://openalex.org/W4366133286","doi":"https://doi.org/10.1016/j.clim.2023.109330","pmid":"https://pubmed.ncbi.nlm.nih.gov/37075949"},"language":"en","primary_location":{"id":"doi:10.1016/j.clim.2023.109330","doi":"https://doi.org/10.1016/j.clim.2023.109330","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.clim.2023.109330","pdf_url":null,"source":{"id":"https://openalex.org/S37169408","display_name":"Clinical Immunology","issn_l":"1521-6616","issn":["1521-6616","1521-7035"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Immunology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5034172361","display_name":"Jingquan He","orcid":"https://orcid.org/0000-0002-9341-8750","observed_orcids":["https://orcid.org/0000-0002-9341-8750"]},"institutions":[{"id":"https://openalex.org/I4405273710","display_name":"Shenzhen Traditional Chinese Medicine Hospital","ror":"https://ror.org/00b16vp10","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4405273710"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jingquan He","raw_affiliation_strings":["Department of Radiotherapy, Shenzhen Traditional Chinese Medicine Hospital, The Forth Clinical Medical College, Guangzhou Traditional Chinese Medicine University, Shenzhen 518033, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiotherapy, Shenzhen Traditional Chinese Medicine Hospital, The Forth Clinical Medical College, Guangzhou Traditional Chinese Medicine University, Shenzhen 518033, China","institution_ids":["https://openalex.org/I4405273710"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078712216","display_name":"Donger Tang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I159948400","display_name":"Jinan University","ror":"https://ror.org/02xe5ns62","country_code":"CN","type":"education","lineage":["https://openalex.org/I159948400"]},{"id":"https://openalex.org/I3045169105","display_name":"Southern University of Science and Technology","ror":"https://ror.org/049tv2d57","country_code":"CN","type":"education","lineage":["https://openalex.org/I3045169105"]},{"id":"https://openalex.org/I4210105608","display_name":"ShenZhen People\u2019s Hospital","ror":"https://ror.org/01hcefx46","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210105608"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Donger Tang","raw_affiliation_strings":["Clinical Medical Research Center, Guangdong Provincial Engineering Research Center of Autoimmune Disease Precision Medicine, Shenzhen Engineering Research Center of Autoimmune Disease, The Second Clinical Medical College of Jinan University, The First Affiliated Hospital of Southern University of Science and Technology, Shenzhen People's Hospital, Shenzhen, Guangdong 518020, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Medical Research Center, Guangdong Provincial Engineering Research Center of Autoimmune Disease Precision Medicine, Shenzhen Engineering Research Center of Autoimmune Disease, The Second Clinical Medical College of Jinan University, The First Affiliated Hospital of Southern University of Science and Technology, Shenzhen People's Hospital, Shenzhen, Guangdong 518020, China","institution_ids":["https://openalex.org/I159948400","https://openalex.org/I3045169105","https://openalex.org/I4210105608"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032974160","display_name":"Dongzhou Jeffrey Liu","orcid":"https://orcid.org/0000-0003-3766-6562","observed_orcids":["https://orcid.org/0000-0003-3766-6562"]},"institutions":[{"id":"https://openalex.org/I159948400","display_name":"Jinan University","ror":"https://ror.org/02xe5ns62","country_code":"CN","type":"education","lineage":["https://openalex.org/I159948400"]},{"id":"https://openalex.org/I3045169105","display_name":"Southern University of Science and Technology","ror":"https://ror.org/049tv2d57","country_code":"CN","type":"education","lineage":["https://openalex.org/I3045169105"]},{"id":"https://openalex.org/I4210105608","display_name":"ShenZhen People\u2019s Hospital","ror":"https://ror.org/01hcefx46","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210105608"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Dongzhou Liu","raw_affiliation_strings":["Clinical Medical Research Center, Guangdong Provincial Engineering Research Center of Autoimmune Disease Precision Medicine, Shenzhen Engineering Research Center of Autoimmune Disease, The Second Clinical Medical College of Jinan University, The First Affiliated Hospital of Southern University of Science and Technology, Shenzhen People's Hospital, Shenzhen, Guangdong 518020, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Medical Research Center, Guangdong Provincial Engineering Research Center of Autoimmune Disease Precision Medicine, Shenzhen Engineering Research Center of Autoimmune Disease, The Second Clinical Medical College of Jinan University, The First Affiliated Hospital of Southern University of Science and Technology, Shenzhen People's Hospital, Shenzhen, Guangdong 518020, China","institution_ids":["https://openalex.org/I159948400","https://openalex.org/I3045169105","https://openalex.org/I4210105608"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001473358","display_name":"Xiaoping Hong","orcid":"https://orcid.org/0000-0002-2062-8394","observed_orcids":["https://orcid.org/0000-0002-2062-8394"]},"institutions":[{"id":"https://openalex.org/I159948400","display_name":"Jinan University","ror":"https://ror.org/02xe5ns62","country_code":"CN","type":"education","lineage":["https://openalex.org/I159948400"]},{"id":"https://openalex.org/I3045169105","display_name":"Southern University of Science and Technology","ror":"https://ror.org/049tv2d57","country_code":"CN","type":"education","lineage":["https://openalex.org/I3045169105"]},{"id":"https://openalex.org/I4210105608","display_name":"ShenZhen People\u2019s Hospital","ror":"https://ror.org/01hcefx46","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210105608"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaoping Hong","raw_affiliation_strings":["Clinical Medical Research Center, Guangdong Provincial Engineering Research Center of Autoimmune Disease Precision Medicine, Shenzhen Engineering Research Center of Autoimmune Disease, The Second Clinical Medical College of Jinan University, The First Affiliated Hospital of Southern University of Science and Technology, Shenzhen People's Hospital, Shenzhen, Guangdong 518020, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Medical Research Center, Guangdong Provincial Engineering Research Center of Autoimmune Disease Precision Medicine, Shenzhen Engineering Research Center of Autoimmune Disease, The Second Clinical Medical College of Jinan University, The First Affiliated Hospital of Southern University of Science and Technology, Shenzhen People's Hospital, Shenzhen, Guangdong 518020, China","institution_ids":["https://openalex.org/I159948400","https://openalex.org/I3045169105","https://openalex.org/I4210105608"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042505120","display_name":"Chiyu Ma","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I159948400","display_name":"Jinan University","ror":"https://ror.org/02xe5ns62","country_code":"CN","type":"education","lineage":["https://openalex.org/I159948400"]},{"id":"https://openalex.org/I3045169105","display_name":"Southern University of Science and Technology","ror":"https://ror.org/049tv2d57","country_code":"CN","type":"education","lineage":["https://openalex.org/I3045169105"]},{"id":"https://openalex.org/I4210105608","display_name":"ShenZhen People\u2019s Hospital","ror":"https://ror.org/01hcefx46","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210105608"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chiyu Ma","raw_affiliation_strings":["Clinical Medical Research Center, Guangdong Provincial Engineering Research Center of Autoimmune Disease Precision Medicine, Shenzhen Engineering Research Center of Autoimmune Disease, The Second Clinical Medical College of Jinan University, The First Affiliated Hospital of Southern University of Science and Technology, Shenzhen People's Hospital, Shenzhen, Guangdong 518020, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Medical Research Center, Guangdong Provincial Engineering Research Center of Autoimmune Disease Precision Medicine, Shenzhen Engineering Research Center of Autoimmune Disease, The Second Clinical Medical College of Jinan University, The First Affiliated Hospital of Southern University of Science and Technology, Shenzhen People's Hospital, Shenzhen, Guangdong 518020, China","institution_ids":["https://openalex.org/I159948400","https://openalex.org/I3045169105","https://openalex.org/I4210105608"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090699341","display_name":"Fengping Zheng","orcid":"https://orcid.org/0000-0002-6065-3500","observed_orcids":["https://orcid.org/0000-0002-6065-3500"]},"institutions":[{"id":"https://openalex.org/I159948400","display_name":"Jinan University","ror":"https://ror.org/02xe5ns62","country_code":"CN","type":"education","lineage":["https://openalex.org/I159948400"]},{"id":"https://openalex.org/I3045169105","display_name":"Southern University of Science and Technology","ror":"https://ror.org/049tv2d57","country_code":"CN","type":"education","lineage":["https://openalex.org/I3045169105"]},{"id":"https://openalex.org/I4210105608","display_name":"ShenZhen People\u2019s Hospital","ror":"https://ror.org/01hcefx46","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210105608"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Fengping Zheng","raw_affiliation_strings":["Clinical Medical Research Center, Guangdong Provincial Engineering Research Center of Autoimmune Disease Precision Medicine, Shenzhen Engineering Research Center of Autoimmune Disease, The Second Clinical Medical College of Jinan University, The First Affiliated Hospital of Southern University of Science and Technology, Shenzhen People's Hospital, Shenzhen, Guangdong 518020, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Medical Research Center, Guangdong Provincial Engineering Research Center of Autoimmune Disease Precision Medicine, Shenzhen Engineering Research Center of Autoimmune Disease, The Second Clinical Medical College of Jinan University, The First Affiliated Hospital of Southern University of Science and Technology, Shenzhen People's Hospital, Shenzhen, Guangdong 518020, China","institution_ids":["https://openalex.org/I159948400","https://openalex.org/I3045169105","https://openalex.org/I4210105608"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067444053","display_name":"Zhipeng Zeng","orcid":"https://orcid.org/0000-0003-3609-9287","observed_orcids":["https://orcid.org/0000-0003-3609-9287"]},"institutions":[{"id":"https://openalex.org/I159948400","display_name":"Jinan University","ror":"https://ror.org/02xe5ns62","country_code":"CN","type":"education","lineage":["https://openalex.org/I159948400"]},{"id":"https://openalex.org/I3045169105","display_name":"Southern University of Science and Technology","ror":"https://ror.org/049tv2d57","country_code":"CN","type":"education","lineage":["https://openalex.org/I3045169105"]},{"id":"https://openalex.org/I4210105608","display_name":"ShenZhen People\u2019s Hospital","ror":"https://ror.org/01hcefx46","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210105608"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhipeng Zeng","raw_affiliation_strings":["Clinical Medical Research Center, Guangdong Provincial Engineering Research Center of Autoimmune Disease Precision Medicine, Shenzhen Engineering Research Center of Autoimmune Disease, The Second Clinical Medical College of Jinan University, The First Affiliated Hospital of Southern University of Science and Technology, Shenzhen People's Hospital, Shenzhen, Guangdong 518020, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Medical Research Center, Guangdong Provincial Engineering Research Center of Autoimmune Disease Precision Medicine, Shenzhen Engineering Research Center of Autoimmune Disease, The Second Clinical Medical College of Jinan University, The First Affiliated Hospital of Southern University of Science and Technology, Shenzhen People's Hospital, Shenzhen, Guangdong 518020, China","institution_ids":["https://openalex.org/I159948400","https://openalex.org/I3045169105","https://openalex.org/I4210105608"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101777167","display_name":"Yumei Chen","orcid":"https://orcid.org/0000-0002-0241-7577","observed_orcids":["https://orcid.org/0000-0002-0241-7577"]},"institutions":[{"id":"https://openalex.org/I159948400","display_name":"Jinan University","ror":"https://ror.org/02xe5ns62","country_code":"CN","type":"education","lineage":["https://openalex.org/I159948400"]},{"id":"https://openalex.org/I3045169105","display_name":"Southern University of Science and Technology","ror":"https://ror.org/049tv2d57","country_code":"CN","type":"education","lineage":["https://openalex.org/I3045169105"]},{"id":"https://openalex.org/I4210105608","display_name":"ShenZhen People\u2019s Hospital","ror":"https://ror.org/01hcefx46","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210105608"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yumei Chen","raw_affiliation_strings":["Clinical Medical Research Center, Guangdong Provincial Engineering Research Center of Autoimmune Disease Precision Medicine, Shenzhen Engineering Research Center of Autoimmune Disease, The Second Clinical Medical College of Jinan University, The First Affiliated Hospital of Southern University of Science and Technology, Shenzhen People's Hospital, Shenzhen, Guangdong 518020, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Medical Research Center, Guangdong Provincial Engineering Research Center of Autoimmune Disease Precision Medicine, Shenzhen Engineering Research Center of Autoimmune Disease, The Second Clinical Medical College of Jinan University, The First Affiliated Hospital of Southern University of Science and Technology, Shenzhen People's Hospital, Shenzhen, Guangdong 518020, China","institution_ids":["https://openalex.org/I159948400","https://openalex.org/I3045169105","https://openalex.org/I4210105608"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006036686","display_name":"Jie Du","orcid":"https://orcid.org/0000-0003-2821-2497","observed_orcids":["https://orcid.org/0000-0003-2821-2497"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jie Du","raw_affiliation_strings":["Biotree Metabolomics Research Center, Biotree, Jiading District, Shanghai 201800, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biotree Metabolomics Research Center, Biotree, Jiading District, Shanghai 201800, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Lin Kang","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Lin Kang","raw_affiliation_strings":["Biotree Metabolomics Research Center, Biotree, Jiading District, Shanghai 201800, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biotree Metabolomics Research Center, Biotree, Jiading District, Shanghai 201800, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100451123","display_name":"Lianghong Yin","orcid":"https://orcid.org/0000-0002-5005-5304","observed_orcids":["https://orcid.org/0000-0002-5005-5304"]},"institutions":[{"id":"https://openalex.org/I4210162753","display_name":"First Affiliated Hospital of Jinan University","ror":"https://ror.org/05d5vvz89","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210162753"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lianghong Yin","raw_affiliation_strings":["Department of Nephrology, The First Affiliated Hospital of Jinan University, Guangzhou 510630, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nephrology, The First Affiliated Hospital of Jinan University, Guangzhou 510630, China","institution_ids":["https://openalex.org/I4210162753"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069923833","display_name":"Qianjin Lu","orcid":"https://orcid.org/0000-0002-4192-4897","observed_orcids":["https://orcid.org/0000-0002-4192-4897","https://orcid.org/0000-0002-1504-4896"]},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]},{"id":"https://openalex.org/I4210153856","display_name":"Second Xiangya Hospital of Central South University","ror":"https://ror.org/053v2gh09","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210153856"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qianjin Lu","raw_affiliation_strings":["Department of Dermatology, Second Xiangya Hospital, Central South University, Hunan Key Laboratory of Medical Epigenomics, Changsha, Hunan 410011, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dermatology, Second Xiangya Hospital, Central South University, Hunan Key Laboratory of Medical Epigenomics, Changsha, Hunan 410011, China","institution_ids":["https://openalex.org/I139660479","https://openalex.org/I4210153856"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5032341066","display_name":"Yong Dai","orcid":"https://orcid.org/0000-0002-6840-9158","observed_orcids":["https://orcid.org/0000-0002-6840-9158"]},"institutions":[{"id":"https://openalex.org/I159948400","display_name":"Jinan University","ror":"https://ror.org/02xe5ns62","country_code":"CN","type":"education","lineage":["https://openalex.org/I159948400"]},{"id":"https://openalex.org/I3045169105","display_name":"Southern University of Science and Technology","ror":"https://ror.org/049tv2d57","country_code":"CN","type":"education","lineage":["https://openalex.org/I3045169105"]},{"id":"https://openalex.org/I4210105608","display_name":"ShenZhen People\u2019s Hospital","ror":"https://ror.org/01hcefx46","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210105608"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Yong Dai","raw_affiliation_strings":["Clinical Medical Research Center, Guangdong Provincial Engineering Research Center of Autoimmune Disease Precision Medicine, Shenzhen Engineering Research Center of Autoimmune Disease, The Second Clinical Medical College of Jinan University, The First Affiliated Hospital of Southern University of Science and Technology, Shenzhen People's Hospital, Shenzhen, Guangdong 518020, China. Electronic address: daiyong22@aliyun.com","Clinical Medical Research Center, Guangdong Provincial Engineering Research Center of Autoimmune Disease Precision Medicine, Shenzhen Engineering Research Center of Autoimmune Disease, The Second Clinical Medical College of Jinan University, The First Affiliated Hospital of Southern University of Science and Technology, Shenzhen People's Hospital, Shenzhen, Guangdong 518020, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Medical Research Center, Guangdong Provincial Engineering Research Center of Autoimmune Disease Precision Medicine, Shenzhen Engineering Research Center of Autoimmune Disease, The Second Clinical Medical College of Jinan University, The First Affiliated Hospital of Southern University of Science and Technology, Shenzhen People's Hospital, Shenzhen, Guangdong 518020, China. Electronic address: daiyong22@aliyun.com","institution_ids":["https://openalex.org/I159948400","https://openalex.org/I3045169105","https://openalex.org/I4210105608"]},{"raw_affiliation_string":"Clinical Medical Research Center, Guangdong Provincial Engineering Research Center of Autoimmune Disease Precision Medicine, Shenzhen Engineering Research Center of Autoimmune Disease, The Second Clinical Medical College of Jinan University, The First Affiliated Hospital of Southern University of Science and Technology, Shenzhen People's Hospital, Shenzhen, Guangdong 518020, China","institution_ids":["https://openalex.org/I159948400","https://openalex.org/I3045169105","https://openalex.org/I4210105608"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5032341066"],"corresponding_institution_ids":["https://openalex.org/I159948400","https://openalex.org/I3045169105","https://openalex.org/I4210105608"],"apc_list":{"value":4090,"currency":"USD","value_usd":4090},"apc_paid":null,"fwci":7.5273,"has_fulltext":false,"cited_by_count":36,"citation_normalized_percentile":{"value":0.98114782,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":93,"max":100},"biblio":{"volume":"251","issue":null,"first_page":"109330","last_page":"109330"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10308","display_name":"Systemic Lupus Erythematosus Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10308","display_name":"Systemic Lupus Erythematosus Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10836","display_name":"Metabolomics and Mass Spectrometry Studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11330","display_name":"Systemic Sclerosis and Related Diseases","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/systemic-lupus-erythematosus","display_name":"systemic lupus erythematosus","score":1.0},{"id":"https://openalex.org/keywords/serum-proteome","display_name":"serum proteome","score":0.8159999847412109},{"id":"https://openalex.org/keywords/serum-metabolome","display_name":"serum metabolome","score":0.996999979019165},{"id":"https://openalex.org/keywords/biomarkers","display_name":"biomarkers","score":0.7889999747276306},{"id":"https://openalex.org/keywords/disease-activity-assessment","display_name":"disease activity assessment","score":0.968999981880188},{"id":"https://openalex.org/keywords/diagnosis","display_name":"diagnosis","score":0.7879999876022339},{"id":"https://openalex.org/keywords/apolipoprotein-a-iv","display_name":"apolipoprotein A-IV","score":0.9039999842643738},{"id":"https://openalex.org/keywords/arachidonic-acid","display_name":"arachidonic acid","score":0.8939999938011169},{"id":"https://openalex.org/keywords/renal-function","display_name":"renal function","score":0.7409999966621399},{"id":"https://openalex.org/keywords/thrombospondin-1","display_name":"thrombospondin-1","score":0.9990000128746033},{"id":"https://openalex.org/keywords/serpinc1","display_name":"SERPINC1","score":1.0},{"id":"https://openalex.org/keywords/random-forest","display_name":"random forest","score":0.4699999988079071}],"concepts":[{"id":"https://openalex.org/C135870905","wikidata":"https://www.wikidata.org/wiki/Q903667","display_name":"Metabolome","level":3,"score":0.8204100131988525},{"id":"https://openalex.org/C2777477808","wikidata":"https://www.wikidata.org/wiki/Q407595","display_name":"Metabolite","level":2,"score":0.6465805172920227},{"id":"https://openalex.org/C21565614","wikidata":"https://www.wikidata.org/wiki/Q12149006","display_name":"Metabolomics","level":2,"score":0.6367749571800232},{"id":"https://openalex.org/C104397665","wikidata":"https://www.wikidata.org/wiki/Q860947","display_name":"Proteome","level":2,"score":0.5844312310218811},{"id":"https://openalex.org/C124535831","wikidata":"https://www.wikidata.org/wiki/Q4915074","display_name":"Biomarker discovery","level":4,"score":0.570634663105011},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.5541243553161621},{"id":"https://openalex.org/C2776912625","wikidata":"https://www.wikidata.org/wiki/Q1485","display_name":"Systemic lupus erythematosus","level":3,"score":0.5231291651725769},{"id":"https://openalex.org/C2781197716","wikidata":"https://www.wikidata.org/wiki/Q864574","display_name":"Biomarker","level":2,"score":0.48840636014938354},{"id":"https://openalex.org/C46111723","wikidata":"https://www.wikidata.org/wiki/Q471857","display_name":"Proteomics","level":3,"score":0.4787682592868805},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4302997887134552},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.4279324412345886},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.36698201298713684},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3608035147190094},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.33254069089889526},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.3300202488899231},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.19042626023292542},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D001327","descriptor_name":"Autoimmune Diseases","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001327","descriptor_name":"Autoimmune Diseases","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001327","descriptor_name":"Autoimmune Diseases","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008180","descriptor_name":"Lupus Erythematosus, Systemic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008180","descriptor_name":"Lupus Erythematosus, Systemic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008180","descriptor_name":"Lupus Erythematosus, Systemic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020543","descriptor_name":"Proteome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020543","descriptor_name":"Proteome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020543","descriptor_name":"Proteome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055442","descriptor_name":"Metabolome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055442","descriptor_name":"Metabolome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055442","descriptor_name":"Metabolome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.clim.2023.109330","doi":"https://doi.org/10.1016/j.clim.2023.109330","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.clim.2023.109330","pdf_url":null,"source":{"id":"https://openalex.org/S37169408","display_name":"Clinical Immunology","issn_l":"1521-6616","issn":["1521-6616","1521-7035"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Immunology","raw_type":"journal-article"},{"id":"pmid:37075949","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37075949","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical immunology (Orlando, Fla.)","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9940000176429749,"id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"display_name":"Life on land","score":0.5199999809265137,"id":"https://metadata.un.org/sdg/15"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":56,"referenced_works":["https://openalex.org/W168011033","https://openalex.org/W1598878817","https://openalex.org/W1886317935","https://openalex.org/W1930205043","https://openalex.org/W1966145904","https://openalex.org/W1982465307","https://openalex.org/W1990208187","https://openalex.org/W2006443808","https://openalex.org/W2022094838","https://openalex.org/W2037587773","https://openalex.org/W2043768205","https://openalex.org/W2048753387","https://openalex.org/W2064999867","https://openalex.org/W2087559924","https://openalex.org/W2089450428","https://openalex.org/W2101142880","https://openalex.org/W2103617764","https://openalex.org/W2107195787","https://openalex.org/W2133465414","https://openalex.org/W2159020137","https://openalex.org/W2159675211","https://openalex.org/W2167540852","https://openalex.org/W2317067718","https://openalex.org/W2321809676","https://openalex.org/W2336843185","https://openalex.org/W2475180165","https://openalex.org/W2514582747","https://openalex.org/W2551404503","https://openalex.org/W2559588208","https://openalex.org/W2586057598","https://openalex.org/W2700962337","https://openalex.org/W2786748810","https://openalex.org/W2800040534","https://openalex.org/W2802065039","https://openalex.org/W2802773414","https://openalex.org/W2806241232","https://openalex.org/W2824420502","https://openalex.org/W2900569176","https://openalex.org/W2901784931","https://openalex.org/W2912343508","https://openalex.org/W2942778916","https://openalex.org/W2949631571","https://openalex.org/W2950595506","https://openalex.org/W2965565685","https://openalex.org/W2972306758","https://openalex.org/W2983092890","https://openalex.org/W3009482910","https://openalex.org/W3023267770","https://openalex.org/W3037210404","https://openalex.org/W3043775031","https://openalex.org/W3046310046","https://openalex.org/W3080144556","https://openalex.org/W3088882900","https://openalex.org/W3091330129","https://openalex.org/W4308872802","https://openalex.org/W6756299060"],"related_works":["https://openalex.org/W1996644818","https://openalex.org/W1965468642","https://openalex.org/W2093500216","https://openalex.org/W2053588008","https://openalex.org/W2916376502","https://openalex.org/W2260452057","https://openalex.org/W3101161779","https://openalex.org/W423371831","https://openalex.org/W2777729175","https://openalex.org/W4295779760"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":12},{"year":2025,"cited_by_count":17},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":2}],"updated_date":"2026-10-22T09:42:04.148104","created_date":"2025-10-10T00:00:00"}