{"id":"https://openalex.org/W4366083313","doi":"https://doi.org/10.15252/msb.202211490","title":"Multisite assessment of reproducibility in high\u2010content cell migration imaging data","display_name":"Multisite assessment of reproducibility in high\u2010content cell migration imaging data","publication_year":2023,"publication_date":"2023-04-17","ids":{"openalex":"https://openalex.org/W4366083313","doi":"https://doi.org/10.15252/msb.202211490","pmid":"https://pubmed.ncbi.nlm.nih.gov/37063090","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/10258559"},"language":"en","primary_location":{"id":"doi:10.15252/msb.202211490","doi":"https://doi.org/10.15252/msb.202211490","is_oa":true,"landing_page_url":"https://doi.org/10.15252/msb.202211490","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.15252/msb.202211490","source":{"id":"https://openalex.org/S200893805","display_name":"Molecular Systems Biology","issn_l":"1744-4292","issn":["1744-4292"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","oarl","poland-200","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Systems Biology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","datacite","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.15252/msb.202211490","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5020280480","display_name":"Jianjiang Hu","orcid":"https://orcid.org/0000-0001-5382-591X","observed_orcids":["https://orcid.org/0000-0001-5382-591X"]},"institutions":[{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Jianjiang Hu","raw_affiliation_strings":["Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden","institution_ids":["https://openalex.org/I28166907"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057682843","display_name":"Xavier Serra\u2010Picamal","orcid":"https://orcid.org/0000-0002-5786-1069","observed_orcids":["https://orcid.org/0000-0002-5786-1069"]},"institutions":[{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Xavier Serra-Picamal","raw_affiliation_strings":["Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden","institution_ids":["https://openalex.org/I28166907"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082642221","display_name":"Gert\u2010Jan Bakker","orcid":"https://orcid.org/0000-0003-3602-0014","observed_orcids":["https://orcid.org/0000-0003-3602-0014"]},"institutions":[{"id":"https://openalex.org/I2802934949","display_name":"Radboud University Medical Center","ror":"https://ror.org/05wg1m734","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2802934949"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Gert-Jan Bakker","raw_affiliation_strings":["Department of Cell Biology, Radboud University Medical Center, Nijmegen, The Netherlands","Department of Medical BioSciences Radboud University Medical Center Nijmegen The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cell Biology, Radboud University Medical Center, Nijmegen, The Netherlands","institution_ids":["https://openalex.org/I2802934949"]},{"raw_affiliation_string":"Department of Medical BioSciences Radboud University Medical Center Nijmegen The Netherlands","institution_ids":["https://openalex.org/I2802934949"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075879769","display_name":"Marleen Van Troys","orcid":"https://orcid.org/0000-0003-4283-8103","observed_orcids":["https://orcid.org/0000-0003-4283-8103"]},"institutions":[{"id":"https://openalex.org/I32597200","display_name":"Ghent University","ror":"https://ror.org/00cv9y106","country_code":"BE","type":"education","lineage":["https://openalex.org/I32597200"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Marleen Van Troys","raw_affiliation_strings":["Department of Biomolecular Medicine, Ghent University, Ghent, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomolecular Medicine, Ghent University, Ghent, Belgium","institution_ids":["https://openalex.org/I32597200"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089714336","display_name":"Sabina E. Winograd-Katz","orcid":"https://orcid.org/0000-0001-8157-2374","observed_orcids":["https://orcid.org/0000-0001-8157-2374"]},"institutions":[{"id":"https://openalex.org/I53964585","display_name":"Weizmann Institute of Science","ror":"https://ror.org/0316ej306","country_code":"IL","type":"education","lineage":["https://openalex.org/I53964585"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"Sabina Winograd-katz","raw_affiliation_strings":["Department of Immunology and Regenerative Biology, Weizmann Institute of Science, Rehovot, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Immunology and Regenerative Biology, Weizmann Institute of Science, Rehovot, Israel","institution_ids":["https://openalex.org/I53964585"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025194417","display_name":"Nil Ege","orcid":"https://orcid.org/0000-0002-3441-3706","observed_orcids":["https://orcid.org/0000-0002-3441-3706"]},"institutions":[{"id":"https://openalex.org/I2801081054","display_name":"The Francis Crick Institute","ror":"https://ror.org/04tnbqb63","country_code":"GB","type":"facility","lineage":["https://openalex.org/I2801081054"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Nil Ege","raw_affiliation_strings":["The Francis Crick Institute, London, United Kingdom","The Francis Crick Institute London UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Francis Crick Institute, London, United Kingdom","institution_ids":["https://openalex.org/I2801081054"]},{"raw_affiliation_string":"The Francis Crick Institute London UK","institution_ids":["https://openalex.org/I2801081054"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084203107","display_name":"Xiaowei Gong","orcid":"https://orcid.org/0000-0002-5120-8587","observed_orcids":["https://orcid.org/0000-0002-5120-8587"]},"institutions":[{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Xiaowei Gong","raw_affiliation_strings":["Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden","institution_ids":["https://openalex.org/I28166907"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073387535","display_name":"Yuliia Didan","orcid":"https://orcid.org/0000-0003-3678-0742","observed_orcids":["https://orcid.org/0000-0003-3678-0742"]},"institutions":[{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Yuliia Didan","raw_affiliation_strings":["Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden","institution_ids":["https://openalex.org/I28166907"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090939146","display_name":"Inna Grosheva","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I53964585","display_name":"Weizmann Institute of Science","ror":"https://ror.org/0316ej306","country_code":"IL","type":"education","lineage":["https://openalex.org/I53964585"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"Inna Grosheva","raw_affiliation_strings":["Department of Immunology and Regenerative Biology, Weizmann Institute of Science, Rehovot, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Immunology and Regenerative Biology, Weizmann Institute of Science, Rehovot, Israel","institution_ids":["https://openalex.org/I53964585"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003331916","display_name":"Omer Polansky","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I53964585","display_name":"Weizmann Institute of Science","ror":"https://ror.org/0316ej306","country_code":"IL","type":"education","lineage":["https://openalex.org/I53964585"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"Omer Polansky","raw_affiliation_strings":["Department of Immunology and Regenerative Biology, Weizmann Institute of Science, Rehovot, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Immunology and Regenerative Biology, Weizmann Institute of Science, Rehovot, Israel","institution_ids":["https://openalex.org/I53964585"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090012984","display_name":"Karima Bakkali","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I32597200","display_name":"Ghent University","ror":"https://ror.org/00cv9y106","country_code":"BE","type":"education","lineage":["https://openalex.org/I32597200"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Karima Bakkali","raw_affiliation_strings":["Department of Biomolecular Medicine, Ghent University, Ghent, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomolecular Medicine, Ghent University, Ghent, Belgium","institution_ids":["https://openalex.org/I32597200"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051090070","display_name":"Evelien Van Hamme","orcid":"https://orcid.org/0000-0001-6136-4711","observed_orcids":["https://orcid.org/0000-0001-6136-4711","https://orcid.org/0000-0001-8815-5485"]},"institutions":[{"id":"https://openalex.org/I4210139803","display_name":"VIB-UGent Center for Inflammation Research","ror":"https://ror.org/04q4ydz28","country_code":"BE","type":"facility","lineage":["https://openalex.org/I2802017950","https://openalex.org/I32597200","https://openalex.org/I4210139803"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Evelien Van Hamme","raw_affiliation_strings":["Bio Imaging Core, VIB Center for Inflammation Research, Ghent, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bio Imaging Core, VIB Center for Inflammation Research, Ghent, Belgium","institution_ids":["https://openalex.org/I4210139803"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067213239","display_name":"Merijn van Erp","orcid":"https://orcid.org/0000-0002-9642-9789","observed_orcids":["https://orcid.org/0000-0002-9642-9789"]},"institutions":[{"id":"https://openalex.org/I2802934949","display_name":"Radboud University Medical Center","ror":"https://ror.org/05wg1m734","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2802934949"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Merijn Van Erp","raw_affiliation_strings":["Department of Cell Biology, Radboud University Medical Center, Nijmegen, The Netherlands","Department of Medical BioSciences Radboud University Medical Center Nijmegen The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cell Biology, Radboud University Medical Center, Nijmegen, The Netherlands","institution_ids":["https://openalex.org/I2802934949"]},{"raw_affiliation_string":"Department of Medical BioSciences Radboud University Medical Center Nijmegen The Netherlands","institution_ids":["https://openalex.org/I2802934949"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015020958","display_name":"Manon Vullings","orcid":"https://orcid.org/0000-0002-9557-0406","observed_orcids":["https://orcid.org/0000-0002-9557-0406"]},"institutions":[{"id":"https://openalex.org/I2802934949","display_name":"Radboud University Medical Center","ror":"https://ror.org/05wg1m734","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2802934949"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Manon Vullings","raw_affiliation_strings":["Department of Cell Biology, Radboud University Medical Center, Nijmegen, The Netherlands","Department of Medical BioSciences Radboud University Medical Center Nijmegen The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cell Biology, Radboud University Medical Center, Nijmegen, The Netherlands","institution_ids":["https://openalex.org/I2802934949"]},{"raw_affiliation_string":"Department of Medical BioSciences Radboud University Medical Center Nijmegen The Netherlands","institution_ids":["https://openalex.org/I2802934949"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005005771","display_name":"Felix Wei\u00df","orcid":"https://orcid.org/0000-0002-4224-9344","observed_orcids":["https://orcid.org/0000-0002-4224-9344"]},"institutions":[{"id":"https://openalex.org/I2802934949","display_name":"Radboud University Medical Center","ror":"https://ror.org/05wg1m734","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2802934949"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Felix Weiss","raw_affiliation_strings":["Department of Cell Biology, Radboud University Medical Center, Nijmegen, The Netherlands","Department of Medical BioSciences Radboud University Medical Center Nijmegen The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cell Biology, Radboud University Medical Center, Nijmegen, The Netherlands","institution_ids":["https://openalex.org/I2802934949"]},{"raw_affiliation_string":"Department of Medical BioSciences Radboud University Medical Center Nijmegen The Netherlands","institution_ids":["https://openalex.org/I2802934949"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020007621","display_name":"Jarama Clucas","orcid":"https://orcid.org/0009-0002-2041-5652","observed_orcids":["https://orcid.org/0009-0002-2041-5652"]},"institutions":[{"id":"https://openalex.org/I2801081054","display_name":"The Francis Crick Institute","ror":"https://ror.org/04tnbqb63","country_code":"GB","type":"facility","lineage":["https://openalex.org/I2801081054"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Jarama Clucas","raw_affiliation_strings":["The Francis Crick Institute, London, United Kingdom","The Francis Crick Institute London UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Francis Crick Institute, London, United Kingdom","institution_ids":["https://openalex.org/I2801081054"]},{"raw_affiliation_string":"The Francis Crick Institute London UK","institution_ids":["https://openalex.org/I2801081054"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046857526","display_name":"Anna M. Dowbaj","orcid":"https://orcid.org/0000-0002-6278-8011","observed_orcids":["https://orcid.org/0000-0002-6278-8011"]},"institutions":[{"id":"https://openalex.org/I2801081054","display_name":"The Francis Crick Institute","ror":"https://ror.org/04tnbqb63","country_code":"GB","type":"facility","lineage":["https://openalex.org/I2801081054"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Anna M. Dowbaj","raw_affiliation_strings":["The Francis Crick Institute, London, United Kingdom","The Francis Crick Institute London UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Francis Crick Institute, London, United Kingdom","institution_ids":["https://openalex.org/I2801081054"]},{"raw_affiliation_string":"The Francis Crick Institute London UK","institution_ids":["https://openalex.org/I2801081054"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078706868","display_name":"Erik A. Sahai","orcid":"https://orcid.org/0000-0002-3932-5086","observed_orcids":["https://orcid.org/0000-0002-3932-5086"]},"institutions":[{"id":"https://openalex.org/I2801081054","display_name":"The Francis Crick Institute","ror":"https://ror.org/04tnbqb63","country_code":"GB","type":"facility","lineage":["https://openalex.org/I2801081054"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Erik Sahai","raw_affiliation_strings":["The Francis Crick Institute, London, United Kingdom","The Francis Crick Institute London UK"],"raw_orcid":"https://orcid.org/0000-0002-3932-5086","affiliations":[{"raw_affiliation_string":"The Francis Crick Institute, London, United Kingdom","institution_ids":["https://openalex.org/I2801081054"]},{"raw_affiliation_string":"The Francis Crick Institute London UK","institution_ids":["https://openalex.org/I2801081054"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041982680","display_name":"Christophe Amp\u00e8","orcid":"https://orcid.org/0000-0002-8554-3594","observed_orcids":["https://orcid.org/0000-0002-8554-3594"]},"institutions":[{"id":"https://openalex.org/I32597200","display_name":"Ghent University","ror":"https://ror.org/00cv9y106","country_code":"BE","type":"education","lineage":["https://openalex.org/I32597200"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Christophe Ampe","raw_affiliation_strings":["Department of Biomolecular Medicine, Ghent University, Ghent, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomolecular Medicine, Ghent University, Ghent, Belgium","institution_ids":["https://openalex.org/I32597200"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046264807","display_name":"Benjamin Geiger","orcid":"https://orcid.org/0000-0001-8559-6373","observed_orcids":["https://orcid.org/0000-0001-8559-6373"]},"institutions":[{"id":"https://openalex.org/I53964585","display_name":"Weizmann Institute of Science","ror":"https://ror.org/0316ej306","country_code":"IL","type":"education","lineage":["https://openalex.org/I53964585"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"Benjamin Geiger","raw_affiliation_strings":["Department of Immunology and Regenerative Biology, Weizmann Institute of Science, Rehovot, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Immunology and Regenerative Biology, Weizmann Institute of Science, Rehovot, Israel","institution_ids":["https://openalex.org/I53964585"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026527299","display_name":"Peter Friedl","orcid":"https://orcid.org/0000-0002-0119-4041","observed_orcids":["https://orcid.org/0000-0002-0119-4041"]},"institutions":[{"id":"https://openalex.org/I2802934949","display_name":"Radboud University Medical Center","ror":"https://ror.org/05wg1m734","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2802934949"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Peter Friedl","raw_affiliation_strings":["Department of Cell Biology, Radboud University Medical Center, Nijmegen, The Netherlands","Department of Medical BioSciences Radboud University Medical Center Nijmegen The Netherlands"],"raw_orcid":"https://orcid.org/0000-0002-0119-4041","affiliations":[{"raw_affiliation_string":"Department of Cell Biology, Radboud University Medical Center, Nijmegen, The Netherlands","institution_ids":["https://openalex.org/I2802934949"]},{"raw_affiliation_string":"Department of Medical BioSciences Radboud University Medical Center Nijmegen The Netherlands","institution_ids":["https://openalex.org/I2802934949"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062707573","display_name":"Matteo Bottai","orcid":"https://orcid.org/0000-0002-3531-2739","observed_orcids":["https://orcid.org/0000-0002-3531-2739"]},"institutions":[{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Matteo Bottai","raw_affiliation_strings":["Division of Biostatistics, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Biostatistics, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden","institution_ids":["https://openalex.org/I28166907"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5012387028","display_name":"Staffan Str\u00f6mblad","orcid":"https://orcid.org/0000-0002-1236-6339","observed_orcids":["https://orcid.org/0000-0002-1236-6339"]},"institutions":[{"id":"https://openalex.org/I28166907","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691","country_code":"SE","type":"education","lineage":["https://openalex.org/I28166907"]}],"countries":["SE"],"is_corresponding":true,"raw_author_name":"Staffan Str\u00f6mblad","raw_affiliation_strings":["Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden"],"raw_orcid":"https://orcid.org/0000-0002-1236-6339","affiliations":[{"raw_affiliation_string":"Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden","institution_ids":["https://openalex.org/I28166907"]}]}],"institutions":[],"countries_distinct_count":5,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5012387028"],"corresponding_institution_ids":["https://openalex.org/I28166907"],"apc_list":{"value":5300,"currency":"USD","value_usd":5300},"apc_paid":{"value":5300,"currency":"USD","value_usd":5300},"fwci":1.0558,"has_fulltext":true,"cited_by_count":9,"citation_normalized_percentile":{"value":0.72214156,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":98},"biblio":{"volume":"19","issue":"6","first_page":"e11490","last_page":"e11490"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11289","display_name":"Single-cell and spatial transcriptomics","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10379","display_name":"Cellular Mechanics and Interactions","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/reproducibility","display_name":"reproducibility","score":0.9369999766349792},{"id":"https://openalex.org/keywords/high-content-imaging","display_name":"high-content imaging","score":0.8159999847412109},{"id":"https://openalex.org/keywords/cell-migration","display_name":"cell migration","score":0.9909999966621399},{"id":"https://openalex.org/keywords/cell-morphology","display_name":"cell morphology","score":0.8429999947547913},{"id":"https://openalex.org/keywords/technical-variation","display_name":"technical variability","score":0.7279999852180481},{"id":"https://openalex.org/keywords/biological-variation","display_name":"biological variation","score":0.9150000214576721},{"id":"https://openalex.org/keywords/batch-effects","display_name":"batch effects","score":0.5429999828338623},{"id":"https://openalex.org/keywords/batch-effect-correction","display_name":"batch effect correction","score":0.7110000252723694},{"id":"https://openalex.org/keywords/meta-analysis","display_name":"meta-analysis","score":0.8019999861717224},{"id":"https://openalex.org/keywords/live-cell-imaging","display_name":"live-cell imaging","score":0.6690000295639038},{"id":"https://openalex.org/keywords/interlaboratory-variability","display_name":"inter-laboratory variability","score":0.6970000267028809},{"id":"https://openalex.org/keywords/perturbation-experiments","display_name":"perturbation experiments","score":0.781000018119812},{"id":"https://openalex.org/keywords/data-sharing","display_name":"data sharing","score":0.4300000071525574}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7996009588241577},{"id":"https://openalex.org/C9893847","wikidata":"https://www.wikidata.org/wiki/Q1425625","display_name":"Reproducibility","level":2,"score":0.7044485211372375},{"id":"https://openalex.org/C157044486","wikidata":"https://www.wikidata.org/wiki/Q5754482","display_name":"High-content screening","level":3,"score":0.5963979959487915},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.41376349329948425},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.27299368381500244},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.1423070728778839},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.12898778915405273},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.05710524320602417}],"mesh":[{"descriptor_ui":"D002465","descriptor_name":"Cell Movement","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":11,"locations":[{"id":"doi:10.15252/msb.202211490","doi":"https://doi.org/10.15252/msb.202211490","is_oa":true,"landing_page_url":"https://doi.org/10.15252/msb.202211490","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.15252/msb.202211490","source":{"id":"https://openalex.org/S200893805","display_name":"Molecular Systems Biology","issn_l":"1744-4292","issn":["1744-4292"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","oarl","poland-200","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Systems Biology","raw_type":"journal-article"},{"id":"doi:10.1101/2022.11.18.516878","doi":"https://doi.org/10.1101/2022.11.18.516878","is_oa":true,"landing_page_url":"https://doi.org/10.1101/2022.11.18.516878","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2022/11/20/2022.11.18.516878.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},{"id":"pmh:oai:pubmedcentral.nih.gov:10258559","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10258559","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10258559/pdf/MSB-19-e11490.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mol Syst Biol","raw_type":"Text"},{"id":"pmid:37063090","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37063090","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular systems biology","raw_type":"Journal Article"},{"id":"pmh:oai:archive.ugent.be:01GY9PZ0V0VK56G044SKRRQKD8","doi":null,"is_oa":false,"landing_page_url":"https://biblio.ugent.be/publication/01GY9PZ0V0VK56G044SKRRQKD8","pdf_url":null,"source":{"id":"https://openalex.org/S4306400478","display_name":"Ghent University Academic Bibliography (Ghent University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I32597200","host_organization_name":"Ghent University","host_organization_lineage":["https://openalex.org/I32597200"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Systems Biology","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:archive.ugent.be:01GZECR8QWJ7F2D6B6QXJ670HX","doi":null,"is_oa":true,"landing_page_url":"https://biblio.ugent.be/publication/01GZECR8QWJ7F2D6B6QXJ670HX","pdf_url":"https://biblio.ugent.be/publication/01GZECR8QWJ7F2D6B6QXJ670HX/file/01GZECSW6PSPFGTX5K2YJMW3TH.pdf","source":{"id":"https://openalex.org/S4306400478","display_name":"Ghent University Academic Bibliography (Ghent University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I32597200","host_organization_name":"Ghent University","host_organization_lineage":["https://openalex.org/I32597200"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ISSN: 1744-4292","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:repository.ubn.ru.nl:2066/293806","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/2066/293806","pdf_url":"https://repository.ubn.ru.nl//bitstream/handle/2066/293806/293806.pdf","source":{"id":"https://openalex.org/S4306401067","display_name":"Radboud Repository (Radboud University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I145872427","host_organization_name":"Radboud University Nijmegen","host_organization_lineage":["https://openalex.org/I145872427"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article / Letter to editor"},{"id":"pmh:oai:doaj.org/article:732ee8bfa8294913a63eccb0f9aa6998","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/732ee8bfa8294913a63eccb0f9aa6998","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Molecular Systems Biology, Vol 19, Iss 6, Pp 1-15 (2023)","raw_type":"article"},{"id":"pmh:oai:figshare.com:article/23523351","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/journal_contribution/Multisite_assessment_of_reproducibility_in_high-content_cell_migration_imaging_data_/23523351","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:ru:oai:repository.ubn.ru.nl:2066/293806","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/2066/293806","pdf_url":null,"source":{"id":"https://openalex.org/S4306401067","display_name":"Radboud Repository (Radboud University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I145872427","host_organization_name":"Radboud University Nijmegen","host_organization_lineage":["https://openalex.org/I145872427"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Molecular Systems Biology, 19","raw_type":"info:eu-repo/semantics/article"},{"id":"doi:10.25418/crick.23523351.v1","doi":"https://doi.org/10.25418/crick.23523351.v1","is_oa":true,"landing_page_url":"https://doi.org/10.25418/crick.23523351.v1","pdf_url":null,"source":{"id":"https://openalex.org/S7407051354","display_name":"The Francis Crick Institute","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2801081054","host_organization_name":"The Francis Crick Institute","host_organization_lineage":["https://openalex.org/I2801081054"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"JournalArticle"}],"best_oa_location":{"id":"doi:10.15252/msb.202211490","doi":"https://doi.org/10.15252/msb.202211490","is_oa":true,"landing_page_url":"https://doi.org/10.15252/msb.202211490","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.15252/msb.202211490","source":{"id":"https://openalex.org/S200893805","display_name":"Molecular Systems Biology","issn_l":"1744-4292","issn":["1744-4292"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","oarl","poland-200","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Systems Biology","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G3763824025","display_name":"Capture, dissemination and analysis of multiscale cell migration data for biological and clinical applications (MULTIMOT)","funder_award_id":"634107","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G434337789","display_name":null,"funder_award_id":"HORIZON2020","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G4375366788","display_name":null,"funder_award_id":"634107 (PHC32\u20102014)","funder_id":"https://openalex.org/F4320332999","funder_display_name":"Horizon 2020 Framework Programme"},{"id":"https://openalex.org/G4700980730","display_name":null,"funder_award_id":"634107","funder_id":"https://openalex.org/F4320332999","funder_display_name":"Horizon 2020 Framework Programme"},{"id":"https://openalex.org/G6267418762","display_name":null,"funder_award_id":"CC2040","funder_id":"https://openalex.org/F4320312060","funder_display_name":"Francis Crick Institute"},{"id":"https://openalex.org/G8955509715","display_name":null,"funder_award_id":"ERC\u2010CoG\u2010617430\u2010DEEPINSIGHT","funder_id":"https://openalex.org/F4320334678","funder_display_name":"European Research Council"}],"funders":[{"id":"https://openalex.org/F4320312060","display_name":"Francis Crick Institute","ror":"https://ror.org/04tnbqb63"},{"id":"https://openalex.org/F4320320300","display_name":"European Commission","ror":"https://ror.org/00k4n6c32"},{"id":"https://openalex.org/F4320321013","display_name":"Radboud Universiteit","ror":"https://ror.org/016xsfp80"},{"id":"https://openalex.org/F4320321491","display_name":"Cancerfonden","ror":"https://ror.org/0527jb766"},{"id":"https://openalex.org/F4320322315","display_name":"Karolinska Institutet","ror":"https://ror.org/056d84691"},{"id":"https://openalex.org/F4320322581","display_name":"Vetenskapsr\u00e5det","ror":"https://ror.org/03zttf063"},{"id":"https://openalex.org/F4320322603","display_name":"Universiteit Gent","ror":"https://ror.org/00cv9y106"},{"id":"https://openalex.org/F4320332999","display_name":"Horizon 2020 Framework Programme","ror":"https://ror.org/00k4n6c32"},{"id":"https://openalex.org/F4320334678","display_name":"European Research Council","ror":"https://ror.org/0472cxd90"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4366083313.pdf","grobid_xml":"https://content.openalex.org/works/W4366083313.grobid-xml"},"referenced_works_count":34,"referenced_works":["https://openalex.org/W1777740471","https://openalex.org/W1951724000","https://openalex.org/W1983937653","https://openalex.org/W2012034410","https://openalex.org/W2033712039","https://openalex.org/W2062872865","https://openalex.org/W2064476731","https://openalex.org/W2066604159","https://openalex.org/W2080522575","https://openalex.org/W2096192437","https://openalex.org/W2110344693","https://openalex.org/W2141500002","https://openalex.org/W2167427729","https://openalex.org/W2170791918","https://openalex.org/W2181077957","https://openalex.org/W2183389629","https://openalex.org/W2289124684","https://openalex.org/W2498090354","https://openalex.org/W2641905542","https://openalex.org/W2766959028","https://openalex.org/W2805461684","https://openalex.org/W2883688299","https://openalex.org/W2950557897","https://openalex.org/W3002417351","https://openalex.org/W3028077246","https://openalex.org/W3113917069","https://openalex.org/W3158185367","https://openalex.org/W3204294504","https://openalex.org/W4205409093","https://openalex.org/W4212959882","https://openalex.org/W4221117452","https://openalex.org/W4237007432","https://openalex.org/W4308804054","https://openalex.org/W4313545069"],"related_works":["https://openalex.org/W4309442708","https://openalex.org/W7118015799","https://openalex.org/W2107267426","https://openalex.org/W2030148428","https://openalex.org/W966878717","https://openalex.org/W4294671636","https://openalex.org/W7204923576","https://openalex.org/W7052843169","https://openalex.org/W2803302343","https://openalex.org/W1946441807"],"abstract_inverted_index":{"High-content":[0],"image-based":[1,129],"cell":[2,71,138],"phenotyping":[3],"provides":[4],"fundamental":[5],"insights":[6],"into":[7],"a":[8],"broad":[9],"variety":[10],"of":[11,41,52,54,70,79,131,141],"life":[12],"science":[13],"disciplines.":[14],"Striving":[15],"for":[16,29],"accurate":[17],"conclusions":[18],"and":[19,34,39,43,46,50,73,92,144],"meaningful":[20],"impact":[21],"demands":[22],"high":[23],"reproducibility":[24,49],"standards,":[25],"with":[26,151],"particular":[27],"relevance":[28],"high-quality":[30],"open-access":[31],"data":[32,67,115],"sharing":[33],"meta-analysis.":[35],"However,":[36,119],"the":[37,48,77,114,125],"sources":[38,78],"degree":[40],"biological":[42],"technical":[44,89,96],"variability,":[45],"thus":[47],"usefulness":[51],"meta-analysis":[53,112,145],"results":[55],"from":[56,116],"live-cell":[57],"microscopy,":[58],"have":[59],"not":[60],"been":[61],"systematically":[62],"investigated.":[63],"Here,":[64],"using":[65],"high-content":[66,137],"describing":[68],"features":[69],"migration":[72],"morphology,":[74],"we":[75],"determine":[76],"variability":[80,97],"across":[81],"different":[82,117],"scales,":[83],"including":[84],"between":[85,99,105],"laboratories,":[86],"persons,":[87,106],"experiments,":[88],"repeats,":[90],"cells,":[91],"time":[93],"points.":[94],"Significant":[95],"occurred":[98],"laboratories":[100],"and,":[101],"to":[102,110,127],"lesser":[103],"extent,":[104],"providing":[107],"low":[108],"value":[109],"direct":[111],"on":[113,147],"laboratories.":[118],"batch":[120,152],"effect":[121],"removal":[122],"markedly":[123],"improved":[124],"possibility":[126],"combine":[128],"datasets":[130],"perturbation":[132,142],"experiments.":[133],"Thus,":[134],"reproducible":[135],"quantitative":[136],"image":[139],"analysis":[140],"effects":[143],"depend":[146],"standardized":[148],"procedures":[149],"combined":[150],"correction.":[153]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2023-04-19T00:00:00"}
