{"id":"https://openalex.org/W4366000494","doi":"https://doi.org/10.1016/j.heares.2023.108769","title":"A new paradigm of hearing loss and preservation with cochlear implants: Learnings from fundamental studies and clinical research","display_name":"A new paradigm of hearing loss and preservation with cochlear implants: Learnings from fundamental studies and clinical research","publication_year":2023,"publication_date":"2023-04-16","ids":{"openalex":"https://openalex.org/W4366000494","doi":"https://doi.org/10.1016/j.heares.2023.108769","pmid":"https://pubmed.ncbi.nlm.nih.gov/37120894"},"language":"en","primary_location":{"id":"doi:10.1016/j.heares.2023.108769","doi":"https://doi.org/10.1016/j.heares.2023.108769","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.heares.2023.108769","pdf_url":null,"source":{"id":"https://openalex.org/S82774605","display_name":"Hearing Research","issn_l":"0378-5955","issn":["0378-5955","1878-5891"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Hearing Research","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1016/j.heares.2023.108769","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5084616366","display_name":"Jonathon R. Kirk","orcid":"https://orcid.org/0000-0003-4945-4399","observed_orcids":["https://orcid.org/0000-0003-4945-4399"]},"institutions":[{"id":"https://openalex.org/I116431938","display_name":"Cochlear (Australia)","ror":"https://ror.org/04hvmsy06","country_code":"AU","type":"company","lineage":["https://openalex.org/I116431938"]},{"id":"https://openalex.org/I99043593","display_name":"Macquarie University","ror":"https://ror.org/01sf06y89","country_code":"AU","type":"education","lineage":["https://openalex.org/I99043593"]}],"countries":["AU"],"is_corresponding":true,"raw_author_name":"Jonathon R. Kirk","raw_affiliation_strings":["Cochlear Limited, 1 University Avenue, Macquarie University, NSW 2109, Australia. Electronic address: JKirk@cochlear.com","Cochlear Limited, 1 University Avenue, Macquarie University, NSW 2109, Australia"],"raw_orcid":"https://orcid.org/0000-0003-4945-4399","affiliations":[{"raw_affiliation_string":"Cochlear Limited, 1 University Avenue, Macquarie University, NSW 2109, Australia. Electronic address: JKirk@cochlear.com","institution_ids":["https://openalex.org/I116431938","https://openalex.org/I99043593"]},{"raw_affiliation_string":"Cochlear Limited, 1 University Avenue, Macquarie University, NSW 2109, Australia","institution_ids":["https://openalex.org/I99043593"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Daniel Smyth","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I99043593","display_name":"Macquarie University","ror":"https://ror.org/01sf06y89","country_code":"AU","type":"education","lineage":["https://openalex.org/I99043593"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Daniel Smyth","raw_affiliation_strings":["Cochlear Limited, 1 University Avenue, Macquarie University, NSW 2109, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cochlear Limited, 1 University Avenue, Macquarie University, NSW 2109, Australia","institution_ids":["https://openalex.org/I99043593"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5020166516","display_name":"Wolfram F. Dueck","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I99043593","display_name":"Macquarie University","ror":"https://ror.org/01sf06y89","country_code":"AU","type":"education","lineage":["https://openalex.org/I99043593"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Wolfram F. Dueck","raw_affiliation_strings":["Cochlear Limited, 1 University Avenue, Macquarie University, NSW 2109, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cochlear Limited, 1 University Avenue, Macquarie University, NSW 2109, Australia","institution_ids":["https://openalex.org/I99043593"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5084616366"],"corresponding_institution_ids":["https://openalex.org/I116431938","https://openalex.org/I99043593"],"apc_list":{"value":4010,"currency":"USD","value_usd":4010},"apc_paid":{"value":4010,"currency":"USD","value_usd":4010},"fwci":0.6454,"has_fulltext":false,"cited_by_count":11,"citation_normalized_percentile":{"value":0.53037383,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"433","issue":null,"first_page":"108769","last_page":"108769"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10283","display_name":"Hearing Loss and Rehabilitation","score":0.9926999807357788,"subfield":{"id":"https://openalex.org/subfields/3616","display_name":"Speech and Hearing"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10283","display_name":"Hearing Loss and Rehabilitation","score":0.9926999807357788,"subfield":{"id":"https://openalex.org/subfields/3616","display_name":"Speech and Hearing"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10334","display_name":"Hearing, Cochlea, Tinnitus, Genetics","score":0.006000000052154064,"subfield":{"id":"https://openalex.org/subfields/2809","display_name":"Sensory Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10861","display_name":"Ear Surgery and Otitis Media","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2733","display_name":"Otorhinolaryngology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cochlear-implants","display_name":"cochlear implants","score":0.8149999976158142},{"id":"https://openalex.org/keywords/cochlear-implantation","display_name":"cochlear implantation","score":0.6370000243186951},{"id":"https://openalex.org/keywords/research-program-planning","display_name":"research program planning","score":0.37599998712539673}],"concepts":[{"id":"https://openalex.org/C2780493683","wikidata":"https://www.wikidata.org/wiki/Q16035842","display_name":"Hearing loss","level":2,"score":0.7102000117301941},{"id":"https://openalex.org/C548259974","wikidata":"https://www.wikidata.org/wiki/Q569965","display_name":"Audiology","level":1,"score":0.6717269420623779},{"id":"https://openalex.org/C4438859","wikidata":"https://www.wikidata.org/wiki/Q186117","display_name":"Timeline","level":2,"score":0.6672204732894897},{"id":"https://openalex.org/C2778882171","wikidata":"https://www.wikidata.org/wiki/Q724965","display_name":"Cochlear implant","level":2,"score":0.6293015480041504},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.6045781373977661},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.4199331998825073},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.36421358585357666},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.15086963772773743},{"id":"https://openalex.org/C95457728","wikidata":"https://www.wikidata.org/wiki/Q309","display_name":"History","level":0,"score":0.07003343105316162},{"id":"https://openalex.org/C166957645","wikidata":"https://www.wikidata.org/wiki/Q23498","display_name":"Archaeology","level":1,"score":0.0},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D003054","descriptor_name":"Cochlear Implants","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003638","descriptor_name":"Deafness","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D006309","descriptor_name":"Hearing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019929","descriptor_name":"Cochlear Implantation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D034381","descriptor_name":"Hearing Loss","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.heares.2023.108769","doi":"https://doi.org/10.1016/j.heares.2023.108769","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.heares.2023.108769","pdf_url":null,"source":{"id":"https://openalex.org/S82774605","display_name":"Hearing Research","issn_l":"0378-5955","issn":["0378-5955","1878-5891"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Hearing Research","raw_type":"journal-article"},{"id":"pmid:37120894","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37120894","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Hearing research","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1016/j.heares.2023.108769","doi":"https://doi.org/10.1016/j.heares.2023.108769","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.heares.2023.108769","pdf_url":null,"source":{"id":"https://openalex.org/S82774605","display_name":"Hearing Research","issn_l":"0378-5955","issn":["0378-5955","1878-5891"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Hearing Research","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9476000070571899,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":135,"referenced_works":["https://openalex.org/W283176880","https://openalex.org/W568902033","https://openalex.org/W607656508","https://openalex.org/W1458323655","https://openalex.org/W1519628569","https://openalex.org/W1523259102","https://openalex.org/W1554908537","https://openalex.org/W1575834180","https://openalex.org/W1580331775","https://openalex.org/W1704469293","https://openalex.org/W1766466668","https://openalex.org/W1871656056","https://openalex.org/W1963993218","https://openalex.org/W1964542888","https://openalex.org/W1968494648","https://openalex.org/W1970495458","https://openalex.org/W1984048709","https://openalex.org/W1984809704","https://openalex.org/W1990003093","https://openalex.org/W1995473057","https://openalex.org/W2003233994","https://openalex.org/W2004668928","https://openalex.org/W2007331949","https://openalex.org/W2007420822","https://openalex.org/W2012609656","https://openalex.org/W2017669080","https://openalex.org/W2021963181","https://openalex.org/W2023575573","https://openalex.org/W2023577994","https://openalex.org/W2029701757","https://openalex.org/W2032018201","https://openalex.org/W2044483083","https://openalex.org/W2045630063","https://openalex.org/W2046124242","https://openalex.org/W2052039751","https://openalex.org/W2055554933","https://openalex.org/W2058468490","https://openalex.org/W2059279864","https://openalex.org/W2065467282","https://openalex.org/W2065850580","https://openalex.org/W2066557022","https://openalex.org/W2071827440","https://openalex.org/W2074330247","https://openalex.org/W2077443590","https://openalex.org/W2083029508","https://openalex.org/W2085793489","https://openalex.org/W2092599789","https://openalex.org/W2093770309","https://openalex.org/W2099136382","https://openalex.org/W2107533694","https://openalex.org/W2112118897","https://openalex.org/W2150120937","https://openalex.org/W2290885260","https://openalex.org/W2296601275","https://openalex.org/W2301820414","https://openalex.org/W2318546625","https://openalex.org/W2341921791","https://openalex.org/W2466589982","https://openalex.org/W2475269466","https://openalex.org/W2507184518","https://openalex.org/W2508274723","https://openalex.org/W2513280892","https://openalex.org/W2519829019","https://openalex.org/W2546797394","https://openalex.org/W2550748697","https://openalex.org/W2565482321","https://openalex.org/W2588292152","https://openalex.org/W2599525239","https://openalex.org/W2606971413","https://openalex.org/W2612527067","https://openalex.org/W2616941053","https://openalex.org/W2619168127","https://openalex.org/W2622795564","https://openalex.org/W2720576945","https://openalex.org/W2746428632","https://openalex.org/W2783228688","https://openalex.org/W2788233716","https://openalex.org/W2790893948","https://openalex.org/W2791331695","https://openalex.org/W2803838570","https://openalex.org/W2805632780","https://openalex.org/W2903812818","https://openalex.org/W2908743779","https://openalex.org/W2912841648","https://openalex.org/W2923326318","https://openalex.org/W2937906090","https://openalex.org/W2949892392","https://openalex.org/W2961712808","https://openalex.org/W2970210969","https://openalex.org/W2983950665","https://openalex.org/W2987261481","https://openalex.org/W2994873915","https://openalex.org/W3004699808","https://openalex.org/W3006439130","https://openalex.org/W3007098053","https://openalex.org/W3007234150","https://openalex.org/W3008931792","https://openalex.org/W3009445037","https://openalex.org/W3013980313","https://openalex.org/W3021404129","https://openalex.org/W3035775262","https://openalex.org/W3046154099","https://openalex.org/W3046293793","https://openalex.org/W3080451311","https://openalex.org/W3089083862","https://openalex.org/W3112846248","https://openalex.org/W3120107140","https://openalex.org/W3127833309","https://openalex.org/W3128914402","https://openalex.org/W3154658958","https://openalex.org/W3157107723","https://openalex.org/W3158792639","https://openalex.org/W3189644576","https://openalex.org/W3198378337","https://openalex.org/W3199277512","https://openalex.org/W3200541145","https://openalex.org/W3200737628","https://openalex.org/W4200069281","https://openalex.org/W4200545795","https://openalex.org/W4213122661","https://openalex.org/W4221099272","https://openalex.org/W4226413517","https://openalex.org/W4281484158","https://openalex.org/W4283013848","https://openalex.org/W4283071956","https://openalex.org/W4283217040","https://openalex.org/W4286506086","https://openalex.org/W4288069885","https://openalex.org/W4298008086","https://openalex.org/W4302424875","https://openalex.org/W4304943043","https://openalex.org/W4306811609","https://openalex.org/W4307570304","https://openalex.org/W4320856832","https://openalex.org/W6723120759"],"related_works":["https://openalex.org/W2012482813","https://openalex.org/W4380186014","https://openalex.org/W2469337514","https://openalex.org/W4200069281","https://openalex.org/W2528380498","https://openalex.org/W2066160189","https://openalex.org/W1766466668","https://openalex.org/W6908833430","https://openalex.org/W2766554451","https://openalex.org/W4396609524"],"abstract_inverted_index":{"In":[0],"2010":[1],"Cochlear":[2],"initiated":[3],"a":[4,83],"coordinated":[5],"preclinical":[6],"research":[7,124,141],"program":[8,30,142],"to":[9,56,149,152],"identify":[10],"the":[11,29,39,50,53,61,64,78,96,137,140],"factors":[12,111,150],"and":[13,23,109,126,156],"underlying":[14],"mechanisms":[15],"of":[16,41,46,52,60,63,136,139,146],"acoustic":[17,42,147],"hearing":[18,69,92,148],"loss":[19,40],"following":[20],"cochlear":[21,79,154],"implantation":[22],"device":[24],"use.":[25],"At":[26],"its":[27],"inception":[28],"was":[31,74],"structured":[32],"around":[33],"several":[34],"major":[35],"hypotheses":[36],"implicated":[37],"in":[38,67,89,99,129],"hearing.":[43],"The":[44],"understanding":[45],"causes":[47],"evolved":[48],"over":[49],"course":[51],"program,":[54],"leading":[55],"an":[57,90],"increased":[58],"appreciation":[59],"role":[62],"biological":[65],"response":[66],"post-implant":[68],"loss.":[70],"A":[71],"systematic":[72],"approach":[73,118],"developed":[75],"which":[76],"mapped":[77],"implant":[80],"journey":[81],"along":[82],"timeline":[84],"that":[85],"considers":[86],"all":[87],"events":[88],"individual's":[91],"history.":[93],"By":[94],"evaluating":[95],"available":[97],"data":[98],"this":[100],"context,":[101],"rather":[102],"than":[103],"by":[104],"discrete":[105],"hypothesis":[106],"testing,":[107],"causative":[108],"associated":[110],"may":[112,127],"be":[113],"more":[114,122],"readily":[115],"detected.":[116],"This":[117],"presents":[119],"opportunities":[120],"for":[121,133,158],"effective":[123],"management":[125],"aid":[128],"identifying":[130],"new":[131],"prospects":[132],"intervention.":[134],"Many":[135],"outcomes":[138],"apply":[143],"beyond":[144],"preservation":[145],"important":[151],"overall":[153],"health":[155],"considerations":[157],"future":[159],"therapies.":[160]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":3},{"year":2022,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2023-04-17T00:00:00"}
