{"id":"https://openalex.org/W4363673038","doi":"https://doi.org/10.1111/hiv.13493","title":"Efficacy, durability, and tolerability of bictegravir/emtricitabine/tenofovir alafenamide for the treatment of HIV in a real\u2010world setting in Belgium","display_name":"Efficacy, durability, and tolerability of bictegravir/emtricitabine/tenofovir alafenamide for the treatment of HIV in a real\u2010world setting in Belgium","publication_year":2023,"publication_date":"2023-04-10","ids":{"openalex":"https://openalex.org/W4363673038","doi":"https://doi.org/10.1111/hiv.13493","pmid":"https://pubmed.ncbi.nlm.nih.gov/37038245"},"language":"en","primary_location":{"id":"doi:10.1111/hiv.13493","doi":"https://doi.org/10.1111/hiv.13493","is_oa":true,"landing_page_url":"https://doi.org/10.1111/hiv.13493","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/hiv.13493","source":{"id":"https://openalex.org/S56736983","display_name":"HIV Medicine","issn_l":"1464-2662","issn":["1464-2662","1468-1293"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"HIV Medicine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/hiv.13493","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5044983238","display_name":"Rakan Nasreddine","orcid":"https://orcid.org/0000-0002-1265-1500","observed_orcids":["https://orcid.org/0000-0002-1265-1500"]},"institutions":[{"id":"https://openalex.org/I4210154425","display_name":"Centre Hospitalier Universitaire de Saint-Pierre","ror":"https://ror.org/05cmp5q80","country_code":"BE","type":"healthcare","lineage":["https://openalex.org/I4210154425"]}],"countries":["BE"],"is_corresponding":true,"raw_author_name":"Rakan Nasreddine","raw_affiliation_strings":["Saint-Pierre University Hospital, Brussels, Belgium"],"raw_orcid":"https://orcid.org/0000-0002-1265-1500","affiliations":[{"raw_affiliation_string":"Saint-Pierre University Hospital, Brussels, Belgium","institution_ids":["https://openalex.org/I4210154425"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074588238","display_name":"\u00c9ric Florence","orcid":"https://orcid.org/0000-0002-7004-9120","observed_orcids":["https://orcid.org/0000-0002-7004-9120","https://orcid.org/0000-0001-8317-7917"]},"institutions":[{"id":"https://openalex.org/I78281549","display_name":"Instituut voor Tropische Geneeskunde","ror":"https://ror.org/03xq4x896","country_code":"BE","type":"nonprofit","lineage":["https://openalex.org/I78281549"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Eric Florence","raw_affiliation_strings":["Institute of Tropical Medicine, Antwerp, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Tropical Medicine, Antwerp, Belgium","institution_ids":["https://openalex.org/I78281549"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062754596","display_name":"Jean Cyr Yombi","orcid":"https://orcid.org/0000-0001-8424-2346","observed_orcids":["https://orcid.org/0000-0001-8424-2346"]},"institutions":[{"id":"https://openalex.org/I1315288073","display_name":"Cliniques Universitaires Saint-Luc","ror":"https://ror.org/03s4khd80","country_code":"BE","type":"healthcare","lineage":["https://openalex.org/I1315288073"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Jean Cyr Yombi","raw_affiliation_strings":["Cliniques Universitaires Saint-Luc, Brussels, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cliniques Universitaires Saint-Luc, Brussels, Belgium","institution_ids":["https://openalex.org/I1315288073"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075732653","display_name":"Sophie Henrard","orcid":"https://orcid.org/0000-0001-9486-5547","observed_orcids":["https://orcid.org/0000-0001-9486-5547"]},"institutions":[{"id":"https://openalex.org/I2802054198","display_name":"Erasmus Hospital","ror":"https://ror.org/05j1gs298","country_code":"BE","type":"healthcare","lineage":["https://openalex.org/I2802054198"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Sophie Henrard","raw_affiliation_strings":["University Clinics of Brussels \u2013 Erasme Hospital  Brussels Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University Clinics of Brussels \u2013 Erasme Hospital  Brussels Belgium","institution_ids":["https://openalex.org/I2802054198"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022228517","display_name":"Gilles Darcis","orcid":"https://orcid.org/0000-0001-8192-1351","observed_orcids":["https://orcid.org/0000-0001-8192-1351"]},"institutions":[{"id":"https://openalex.org/I4210134544","display_name":"Centre Hospitalier Universitaire de Li\u00e8ge","ror":"https://ror.org/044s61914","country_code":"BE","type":"healthcare","lineage":["https://openalex.org/I4210134544"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Gilles Darcis","raw_affiliation_strings":["Li\u00e8ge University Hospital  Li\u00e8ge Belgium"],"raw_orcid":"https://orcid.org/0000-0001-8192-1351","affiliations":[{"raw_affiliation_string":"Li\u00e8ge University Hospital  Li\u00e8ge Belgium","institution_ids":["https://openalex.org/I4210134544"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027439624","display_name":"Jens Tomas Van Praet","orcid":"https://orcid.org/0000-0002-7125-7001","observed_orcids":["https://orcid.org/0000-0002-7125-7001"]},"institutions":[{"id":"https://openalex.org/I4210123377","display_name":"AZ Sint-Jan","ror":"https://ror.org/030h1vb90","country_code":"BE","type":"healthcare","lineage":["https://openalex.org/I4210123377"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Jens Van Praet","raw_affiliation_strings":["AZ Sint-Jan Brugge-Oostende, Brugge, Belgium"],"raw_orcid":"https://orcid.org/0000-0002-7125-7001","affiliations":[{"raw_affiliation_string":"AZ Sint-Jan Brugge-Oostende, Brugge, Belgium","institution_ids":["https://openalex.org/I4210123377"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076699359","display_name":"Linos Vandekerckhove","orcid":"https://orcid.org/0000-0002-8600-1631","observed_orcids":["https://orcid.org/0000-0002-8600-1631"]},"institutions":[{"id":"https://openalex.org/I2801227569","display_name":"Ghent University Hospital","ror":"https://ror.org/00xmkp704","country_code":"BE","type":"healthcare","lineage":["https://openalex.org/I2801227569"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Linos Vandekerckhove","raw_affiliation_strings":["Ghent University Hospital, Ghent, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ghent University Hospital, Ghent, Belgium","institution_ids":["https://openalex.org/I2801227569"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063541183","display_name":"Sabine Danielle Allard","orcid":"https://orcid.org/0000-0002-1565-7318","observed_orcids":["https://orcid.org/0000-0002-1565-7318"]},"institutions":[{"id":"https://openalex.org/I4210126764","display_name":"Universitair Ziekenhuis Brussel","ror":"https://ror.org/038f7y939","country_code":"BE","type":"healthcare","lineage":["https://openalex.org/I4210126764"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Sabine D. Allard","raw_affiliation_strings":["Universitair Ziekenhuis Brussel, Brussels, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universitair Ziekenhuis Brussel, Brussels, Belgium","institution_ids":["https://openalex.org/I4210126764"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033329287","display_name":"R\u00e9my P. Demeester","orcid":"https://orcid.org/0000-0002-2979-4321","observed_orcids":["https://orcid.org/0000-0002-2979-4321"]},"institutions":[{"id":"https://openalex.org/I4210152698","display_name":"Grand Charleroi Hospital","ror":"https://ror.org/05ma41w62","country_code":"BE","type":"healthcare","lineage":["https://openalex.org/I4210152698"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"R\u00e9my Demeester","raw_affiliation_strings":["University Hospital of Charleroi, Lodelinsart, Charleroi, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University Hospital of Charleroi, Lodelinsart, Charleroi, Belgium","institution_ids":["https://openalex.org/I4210152698"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091764159","display_name":"Peter Messiaen","orcid":"https://orcid.org/0000-0001-9619-1291","observed_orcids":["https://orcid.org/0000-0001-9619-1291"]},"institutions":[{"id":"https://openalex.org/I4210095612","display_name":"Jessa Hospital","ror":"https://ror.org/00qkhxq50","country_code":"BE","type":"healthcare","lineage":["https://openalex.org/I4210095612"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Peter Messiaen","raw_affiliation_strings":["Jessa Hospital, Hasselt, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Jessa Hospital, Hasselt, Belgium","institution_ids":["https://openalex.org/I4210095612"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038033666","display_name":"Nathalie Ausselet","orcid":"https://orcid.org/0000-0002-4094-7923","observed_orcids":["https://orcid.org/0000-0002-4094-7923"]},"institutions":[{"id":"https://openalex.org/I4210093617","display_name":"CHU Dinant Godinne UCL Namur","ror":"https://ror.org/00ntbvq76","country_code":"BE","type":"healthcare","lineage":["https://openalex.org/I4210093617"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Nathalie Ausselet","raw_affiliation_strings":["UCL University Hospital Namur-Godinne, Yvoir, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UCL University Hospital Namur-Godinne, Yvoir, Belgium","institution_ids":["https://openalex.org/I4210093617"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007869839","display_name":"Marc Delforge","orcid":"https://orcid.org/0000-0001-9002-0598","observed_orcids":["https://orcid.org/0000-0001-9002-0598"]},"institutions":[{"id":"https://openalex.org/I4210154425","display_name":"Centre Hospitalier Universitaire de Saint-Pierre","ror":"https://ror.org/05cmp5q80","country_code":"BE","type":"healthcare","lineage":["https://openalex.org/I4210154425"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Marc Delforge","raw_affiliation_strings":["Saint-Pierre University Hospital, Brussels, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Saint-Pierre University Hospital, Brussels, Belgium","institution_ids":["https://openalex.org/I4210154425"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5107842158","display_name":"St\u00e9phane De Wit","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210154425","display_name":"Centre Hospitalier Universitaire de Saint-Pierre","ror":"https://ror.org/05cmp5q80","country_code":"BE","type":"healthcare","lineage":["https://openalex.org/I4210154425"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"St\u00e9phane De Wit","raw_affiliation_strings":["Saint-Pierre University Hospital, Brussels, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Saint-Pierre University Hospital, Brussels, Belgium","institution_ids":["https://openalex.org/I4210154425"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":11,"corresponding_author_ids":["https://openalex.org/A5044983238"],"corresponding_institution_ids":["https://openalex.org/I4210154425"],"apc_list":{"value":3760,"currency":"USD","value_usd":3760},"apc_paid":null,"fwci":5.3739,"has_fulltext":true,"cited_by_count":29,"citation_normalized_percentile":{"value":0.96870206,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":95,"max":99},"biblio":{"volume":"24","issue":"8","first_page":"914","last_page":"924"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10526","display_name":"HIV/AIDS drug development and treatment","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10526","display_name":"HIV/AIDS drug development and treatment","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10082","display_name":"HIV/AIDS Research and Interventions","score":0.0017000000225380063,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10112","display_name":"HIV Research and Treatment","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/bictegravir-emtricitabine-tenofovir-alafenamide","display_name":"bictegravir/emtricitabine/tenofovir alafenamide","score":0.9909999966621399},{"id":"https://openalex.org/keywords/hiv-1","display_name":"HIV-1","score":0.5789999961853027},{"id":"https://openalex.org/keywords/antiretroviral-therapy","display_name":"antiretroviral therapy","score":0.8899999856948853},{"id":"https://openalex.org/keywords/viral-suppression","display_name":"viral suppression","score":0.9010000228881836},{"id":"https://openalex.org/keywords/drug-resistance","display_name":"drug resistance","score":0.5720000267028809},{"id":"https://openalex.org/keywords/treatment-discontinuation","display_name":"treatment discontinuation","score":0.5870000123977661},{"id":"https://openalex.org/keywords/tolerability","display_name":"tolerability","score":0.7300000190734863},{"id":"https://openalex.org/keywords/weight-gain","display_name":"weight gain","score":0.8820000290870667},{"id":"https://openalex.org/keywords/treatment-naive-and-treatment-experienced-patients","display_name":"treatment-naive and treatment-experienced patients","score":0.703000009059906},{"id":"https://openalex.org/keywords/real-world-effectiveness","display_name":"real-world effectiveness","score":0.6399999856948853},{"id":"https://openalex.org/keywords/belgium","display_name":"Belgium","score":0.8629999756813049},{"id":"https://openalex.org/keywords/integrase-strand-transfer-inhibitors","display_name":"integrase strand transfer inhibitors","score":0.6629999876022339},{"id":"https://openalex.org/keywords/nucleoside-reverse-transcriptase-inhibitors","display_name":"nucleoside reverse transcriptase inhibitors","score":0.9430000185966492}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8877792358398438},{"id":"https://openalex.org/C2778375690","wikidata":"https://www.wikidata.org/wiki/Q7814214","display_name":"Tolerability","level":3,"score":0.8716970682144165},{"id":"https://openalex.org/C2779778239","wikidata":"https://www.wikidata.org/wiki/Q422604","display_name":"Emtricitabine","level":5,"score":0.8702515363693237},{"id":"https://openalex.org/C2911190787","wikidata":"https://www.wikidata.org/wiki/Q22075912","display_name":"Tenofovir alafenamide","level":5,"score":0.7880302667617798},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6271277666091919},{"id":"https://openalex.org/C197934379","wikidata":"https://www.wikidata.org/wiki/Q2047938","display_name":"Adverse effect","level":2,"score":0.5678231120109558},{"id":"https://openalex.org/C142462285","wikidata":"https://www.wikidata.org/wiki/Q2528140","display_name":"Viral load","level":3,"score":0.4743080139160156},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.3666032552719116},{"id":"https://openalex.org/C3013748606","wikidata":"https://www.wikidata.org/wiki/Q15787","display_name":"Human immunodeficiency virus (HIV)","level":2,"score":0.2989231050014496},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.2871997654438019},{"id":"https://openalex.org/C2993143319","wikidata":"https://www.wikidata.org/wiki/Q583050","display_name":"Antiretroviral therapy","level":4,"score":0.14157217741012573}],"mesh":[{"descriptor_ui":"D000068679","descriptor_name":"Emtricitabine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000068698","descriptor_name":"Tenofovir","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":false},{"descriptor_ui":"D000225","descriptor_name":"Adenine","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000409","descriptor_name":"Alanine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000577","descriptor_name":"Amides","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001530","descriptor_name":"Belgium","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004338","descriptor_name":"Drug Combinations","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006575","descriptor_name":"Heterocyclic Compounds, 3-Ring","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D006576","descriptor_name":"Heterocyclic Compounds, 4 or More Rings","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010879","descriptor_name":"Piperazines","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011728","descriptor_name":"Pyridones","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015331","descriptor_name":"Cohort Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019380","descriptor_name":"Anti-HIV Agents","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true}],"locations_count":9,"locations":[{"id":"doi:10.1111/hiv.13493","doi":"https://doi.org/10.1111/hiv.13493","is_oa":true,"landing_page_url":"https://doi.org/10.1111/hiv.13493","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/hiv.13493","source":{"id":"https://openalex.org/S56736983","display_name":"HIV Medicine","issn_l":"1464-2662","issn":["1464-2662","1468-1293"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"HIV Medicine","raw_type":"journal-article"},{"id":"pmid:37038245","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37038245","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"HIV medicine","raw_type":"Journal Article"},{"id":"pmh:oai:orbi.ulg.ac.be:2268/304048","doi":null,"is_oa":true,"landing_page_url":"https://orbi.uliege.be/handle/2268/304048","pdf_url":"https://orbi.uliege.be/bitstream/2268/304048/1/HIV%20Medicine%20-%202023%20-%20Nasreddine%20-%20Efficacy%20%20durability%20%20and%20tolerability%20of%20bictegravir%20emtricitabine%20tenofovir.pdf","source":{"id":"https://openalex.org/S4306401300","display_name":"ORBi (University of Li\u00e8ge)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I157674565","host_organization_name":"University of Li\u00e8ge","host_organization_lineage":["https://openalex.org/I157674565"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"HIV Medicine (2023-04-10)","raw_type":"http://purl.org/coar/resource_type/c_6501"},{"id":"pmh:oai:archive.ugent.be:01GY2HC4H4G5MZ3AS56VV1KKQP","doi":null,"is_oa":false,"landing_page_url":"https://biblio.ugent.be/publication/01GY2HC4H4G5MZ3AS56VV1KKQP","pdf_url":null,"source":{"id":"https://openalex.org/S4306400478","display_name":"Ghent University Academic Bibliography (Ghent University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I32597200","host_organization_name":"Ghent University","host_organization_lineage":["https://openalex.org/I32597200"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ISSN: 1468-1293","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:dial.uclouvain.be:boreal:281457","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/2078.1/281457","pdf_url":null,"source":{"id":"https://openalex.org/S4306400166","display_name":"Digital Access to Libraries","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2800384882","host_organization_name":"Harris County Public Library","host_organization_lineage":["https://openalex.org/I2800384882"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"HIV medicine, Vol. 24, no.8, p. 914-924 (2023)","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:documentserver.uhasselt.be:1942/38926","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/1942/38926","pdf_url":null,"source":{"id":"https://openalex.org/S4306401926","display_name":"Document Server@UHasselt (UHasselt)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I878454856","host_organization_name":"Hasselt University","host_organization_lineage":["https://openalex.org/I878454856"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:documentserver.uhasselt.be:1942/40272","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/1942/40272","pdf_url":null,"source":{"id":"https://openalex.org/S4306401926","display_name":"Document Server@UHasselt (UHasselt)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I878454856","host_organization_name":"Hasselt University","host_organization_lineage":["https://openalex.org/I878454856"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:lirias2repo.kuleuven.be:20.500.12942/741706","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37038245","pdf_url":null,"source":{"id":"https://openalex.org/S4306401954","display_name":"Lirias (KU Leuven)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I99464096","host_organization_name":"KU Leuven","host_organization_lineage":["https://openalex.org/I99464096"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"HIV Medicine, vol. 24 (8), (914-924)","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:vubissmart:VUBISSMART:2000:264824","doi":null,"is_oa":false,"landing_page_url":"https://biblio.vub.ac.be/vubir/efficacy-durability-and-tolerability-of-bictegraviremtricitabinetenofovir-alafenamide-for-the-treatment-of-hiv-in-a-realworld-setting-in-belgium(7c5ea2e4-8187-4c48-8352-8a81bc26f88c).html","pdf_url":null,"source":{"id":"https://openalex.org/S4306402573","display_name":"VUBIR (Vrije Universiteit Brussel)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I13469542","host_organization_name":"Vrije Universiteit Brussel","host_organization_lineage":["https://openalex.org/I13469542"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article"}],"best_oa_location":{"id":"doi:10.1111/hiv.13493","doi":"https://doi.org/10.1111/hiv.13493","is_oa":true,"landing_page_url":"https://doi.org/10.1111/hiv.13493","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/hiv.13493","source":{"id":"https://openalex.org/S56736983","display_name":"HIV Medicine","issn_l":"1464-2662","issn":["1464-2662","1468-1293"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"HIV Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320308573","display_name":"Gilead Sciences","ror":"https://ror.org/056546b03"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4363673038.pdf","grobid_xml":"https://content.openalex.org/works/W4363673038.grobid-xml"},"referenced_works_count":34,"referenced_works":["https://openalex.org/W1985369236","https://openalex.org/W2102925901","https://openalex.org/W2113255660","https://openalex.org/W2123179942","https://openalex.org/W2142344105","https://openalex.org/W2588766650","https://openalex.org/W2752494178","https://openalex.org/W2753489952","https://openalex.org/W2800690991","https://openalex.org/W2807835948","https://openalex.org/W2807931585","https://openalex.org/W2893518254","https://openalex.org/W2915372808","https://openalex.org/W2944376193","https://openalex.org/W2969479109","https://openalex.org/W2979917028","https://openalex.org/W2980839050","https://openalex.org/W2990136673","https://openalex.org/W3005312287","https://openalex.org/W3042726352","https://openalex.org/W3045364765","https://openalex.org/W3091955100","https://openalex.org/W3118597679","https://openalex.org/W3120317043","https://openalex.org/W3120425997","https://openalex.org/W3131503802","https://openalex.org/W3148155971","https://openalex.org/W3173127938","https://openalex.org/W3190062572","https://openalex.org/W3198977227","https://openalex.org/W4206346925","https://openalex.org/W4239572789","https://openalex.org/W4244459571","https://openalex.org/W4247873649"],"related_works":["https://openalex.org/W4417397248","https://openalex.org/W4397290515","https://openalex.org/W4206346925","https://openalex.org/W7204592865","https://openalex.org/W7125206005","https://openalex.org/W4367835252","https://openalex.org/W4411371017","https://openalex.org/W3198063430","https://openalex.org/W7005631447","https://openalex.org/W6996346777"],"abstract_inverted_index":{"OBJECTIVES:":[0],"Our":[1],"objective":[2],"was":[3,23,53,142,172,210,234,247,278,282],"to":[4,187,240],"evaluate":[5],"the":[6,108,149,201,206,216],"efficacy,":[7],"durability,":[8],"and":[9,33,46,69,95,112,116,166,194,224,242,280],"tolerability":[10,104],"of":[11,55,77,85,97,102,105,118,139,179,251,268,274],"bictegravir/emtricitabine/tenofovir":[12],"alafenamide":[13],"(BIC/FTC/TAF)":[14],"in":[15,19,114,148,174,249,264],"a":[16,24,121,243,265],"real-world":[17,257],"setting":[18],"Belgium.":[20],"METHODS:":[21],"This":[22],"retrospective,":[25],"multicentre":[26],"cohort":[27],"study":[28,110],"involving":[29],"adult":[30],"treatment-na\u00efve":[31],"(TN)":[32],"treatment-experienced":[34],"(TE)":[35],"people":[36],"living":[37],"with":[38,144,181,215,270],"HIV":[39],"receiving":[40],"BIC/FTC/TAF":[41,106,259],"between":[42],"1":[43],"January":[44],"2019":[45],"30":[47],"September":[48],"2020.":[49],"The":[50,71],"primary":[51],"outcome":[52],"rate":[54,138],"virological":[56,78,140,262],"suppression":[57,79,141],"(plasma":[58],"HIV-1":[59],"viral":[60,83],"load":[61],"<50":[62],"copies/mL;":[63],"on-treatment":[64],"analysis)":[65],"at":[66,100,125,168,231],"weeks":[67],"24":[68],"48.":[70,127],"main":[72],"secondary":[73],"outcomes":[74],"included":[75],"loss":[76],"(LVS;":[80],"two":[81],"consecutive":[82],"loads":[84],">200":[86],"copies/mL":[87],"after":[88],"being":[89,219],"virologically":[90],"suppressed)":[91],"by":[92],"week":[93,126,232],"48":[94,135,233],"analysis":[96],"resistance-associated":[98,185],"mutations":[99,186],"time":[101],"LVS;":[103],"over":[107],"48-week":[109],"period;":[111],"change":[113],"weight":[115,123,229,245],"proportion":[117],"participants":[119,131],"reporting":[120],">10%":[122,244],"gain":[124,230],"RESULTS:":[128],"Overall,":[129],"2001":[130],"were":[132],"included.":[133],"Through":[134],"weeks,":[136],"overall":[137],"93.5%,":[143],"similar":[145],"results":[146],"observed":[147,173,248],"following":[150],"subgroups:":[151],"age":[152],"\u226550":[153],"years":[154],"(92.7%),":[155],"women":[156],"(92.8%),":[157],"Black":[158],"sub-Saharan":[159],"African":[160],"(91%),":[161],"TN":[162],"(94%),":[163],"TE":[164],"(93.2%),":[165],"non-suppressed":[167],"baseline":[169],"(86.6%).":[170],"LVS":[171],"0.7%":[175],"(n":[176],"=":[177],"14)":[178],"participants,":[180],"one":[182],"participant":[183],"developing":[184],"nucleoside":[188],"reverse":[189],"transcriptase":[190],"inhibitors":[191,198],"(184":[192],"V)":[193],"integrase":[195],"strand":[196],"transfer":[197],"(263KR).":[199],"Of":[200],"131":[202],"(6.5%)":[203],"treatment":[204,281],"discontinuations,":[205],"most":[207,217],"common":[208],"reason":[209],"an":[211],"adverse":[212],"event":[213],"(2.4%),":[214],"frequent":[218],"central":[220],"nervous":[221],"system/psychiatric":[222],"(0.4%)":[223,226],"gastrointestinal":[225],"toxicity.":[227],"Median":[228],"2":[235],"kg":[236],"(interquartile":[237],"range":[238],"-1":[239],"5),":[241],"increase":[246],"11.6%":[250],"participants.":[252],"CONCLUSION:":[253],"In":[254],"this":[255],"large":[256],"cohort,":[258],"showed":[260],"excellent":[261],"efficacy":[263],"diverse":[266],"population":[267],"patients":[269],"HIV.":[271],"Rare":[272],"occurrence":[273],"emergent":[275],"drug":[276],"resistance":[277],"observed,":[279],"well":[283],"tolerated.":[284]},"counts_by_year":[{"year":2026,"cited_by_count":7},{"year":2025,"cited_by_count":9},{"year":2024,"cited_by_count":10},{"year":2023,"cited_by_count":3}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2023-04-11T00:00:00"}